Abstract:
:A 25-year-old female patient developed headache and papilledema under sulphasalazine treatment for ulcerative colitis. The patient met the International Headache Society's criteria for idiopathic intracranial hypertension. Sulphasalazine was discontinued and the patient was given azathioprine for ulcerative colitis and acetazolamide for intracranial hypertension. Three weeks later, her examination was normal and lumbar puncture revealed an opening pressure of 180-mm H(2)O. Sulphasalazine is a product of 5 aminosalicylate (5 ASA) and there seems to be a relationship between the administration of sulphasalazine and the onset of intracranial hypertension symptoms. Early diagnosis of intracranial hypertension is important in patients with ulcerative colitis receiving 5 ASA treatment to prevent visual complications.
journal_name
Headachejournal_title
Headacheauthors
Sevgi E,Yalcin G,Kansu T,Varli Kdoi
10.1111/j.1526-4610.2007.00992.xsubject
Has Abstractpub_date
2008-02-01 00:00:00pages
296-8issue
2eissn
0017-8748issn
1526-4610pii
HED992journal_volume
48pub_type
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