Postural headache and cerebrospinal fluid leak: believing is seeing.


:A 33-year-old woman developed persistent postural headache following epidural anesthesia (L2-L3 level). Iohexol myelography (L5-S1 puncture) demonstrated no epidural extravasation of contrast material (Figure A), but subsequent computed tomography (CT) axial images (B, C) revealed leakage of dye through the needle track of the L5-S1 puncture (arrows). No leakage of contrast medium was found at the site of the L2-L3 epidural puncture.






Goadsby P,Jager HR





Has Abstract


2003-06-01 00:00:00


681; discussion 681














  • Childhood maltreatment and migraine (part III). Association with comorbid pain conditions.

    abstract:OBJECTIVE:To evaluate in a headache clinic population the relationship of childhood maltreatment on the prevalence of pain conditions comorbid with migraine. BACKGROUND:Childhood maltreatment is highly prevalent and has been frequently associated with recurrent headache. The relationship of maltreatment and pain has, ...


    pub_type: 杂志文章


    authors: Tietjen GE,Brandes JL,Peterlin BL,Eloff A,Dafer RM,Stein MR,Drexler E,Martin VT,Hutchinson S,Aurora SK,Recober A,Herial NA,Utley C,White L,Khuder SA

    更新日期:2010-01-01 00:00:00

  • Dihydroergotamine and its use in migraine with posterior fossa symptoms.

    abstract:BACKGROUND:Dihydroergotamine (DHE) has been used for decades to treat migraine, but is currently contraindicated in patients with hemiplegic migraine and basilar-type migraine (BTM). OBJECTIVE:To assess the safety of DHE in patients with symptoms of BTM that do not meet criteria for BTM. METHODS:Retrospective analysi...


    pub_type: 杂志文章


    authors: Whyte CA,Stillman MJ,Tepper SJ

    更新日期:2010-10-01 00:00:00

  • A controlled evaluation of the addition of cognitive therapy to a home-based biofeedback and relaxation treatment of vascular headache.

    abstract::Seventy-six patients with vascular (migraine or mixed migraine and tension) headache (HA) participated in a controlled evaluation of a minimal-therapist-contact, largely home-based, treatment program which combined relaxation (R) training with thermal biofeedback (TBF). One group received TBF + R administered in 3 off...


    pub_type: 临床试验,杂志文章


    authors: Blanchard EB,Appelbaum KA,Nicholson NL,Radnitz CL,Morrill B,Michultka D,Kirsch C,Hillhouse J,Dentinger MP

    更新日期:1990-05-01 00:00:00

  • Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study.

    abstract:OBJECTIVE:To assess the acute treatment of pregnant women presenting to a hospital with migraine. BACKGROUND:Migraine is a common problem in pregnancy; however, migraine treatment is challenging in pregnant women for fears of medication teratogenicity and lack of data in this population. To date, no study has directly...


    pub_type: 杂志文章


    authors: Hamilton KT,Robbins MS

    更新日期:2019-02-01 00:00:00

  • Longitudinal Analysis of Patient-Reported Outcomes From an Interdisciplinary Pediatric Pain Rehabilitation Program for Children With Chronic Migraine and Headache.

    abstract:BACKGROUND:Many children suffering from chronic headache and migraine present with comorbid functional disability, including physical, social, emotional, and academic activities. For children severely impaired by headache, intensive interdisciplinary pain rehabilitation treatment (IIPT) can improve functioning. However...


    pub_type: 杂志文章


    authors: Benore E,Webster EE,Wang L,Banez G

    更新日期:2018-11-01 00:00:00

  • Headache as only symptom in multiple cervical artery dissection.

    abstract::We describe a patient with atypical headache as the only presenting symptom of spontaneous triple cervical artery dissection. As the patient suffered from arterial hypertension, a causative relation between headache and arterial hypertension was initially taken into consideration. However, four-vessel arteriography di...


    pub_type: 杂志文章


    authors: Buyle M,Engelborghs S,Kunnen J,De Deyn PP

    更新日期:2001-05-01 00:00:00

  • Validation of the Portuguese version of ID-Migraine.

    abstract:BACKGROUND:Migraine is a highly prevalent disorder that imposes an important burden of disability to patients and has social and economic impact in developed countries. A good screening tool for migraine diagnosis is useful to improve disease identification and therapeutic approaches, hopefully reducing the burden of m...


    pub_type: 杂志文章


    authors: Gil-Gouveia R,Martins I

    更新日期:2010-03-01 00:00:00

  • Stimulation of Posterior Thalamic Nuclei Induces Photophobic Behavior in Mice.

    abstract:OBJECTIVE:A hallmark of migraine is photophobia. In mice, photophobia-like behavior is induced by calcitonin gene-related peptide (CGRP), a neuropeptide known to be a key player in migraine. In this study, we sought to identify sites within the brain from which CGRP could induce photophobia. DESIGN:We focused on the p...


    pub_type: 杂志文章


    authors: Sowers LP,Wang M,Rea BJ,Taugher RJ,Kuburas A,Kim Y,Wemmie JA,Walker CS,Hay DL,Russo AF

    更新日期:2020-10-01 00:00:00

  • Prevalence of migraine in patients with restless legs syndrome: a case-control study.

    abstract:OBJECTIVES:To assess and compare the prevalence of migraine in patients with restless legs syndrome (RLS) and matched controls. BACKGROUND:Recent studies have suggested an association between migraine and RLS. Our work is the first case-control study on this subject performed in an RLS population. METHODS:A case-cont...


    pub_type: 杂志文章


    authors: Fernández-Matarrubia M,Cuadrado ML,Sánchez-Barros CM,Martínez-Orozco FJ,Fernández-Pérez C,Villalibre I,Ramírez-Nicolás B,Porta-Etessam J

    更新日期:2014-09-01 00:00:00

  • Central sensitization theory of migraine: clinical implications.

    abstract::The clinical science of migraine headache continues to evolve. Theories of the pathophysiology of migraine have progressed from the early vascular basis of migraine to more complex current theories that emphasize the centrality of neuronal dysfunction. The most recently articulated theory of migraine is the central se...


    pub_type: 杂志文章,评审


    authors: Dodick D,Silberstein S

    更新日期:2006-11-01 00:00:00

  • Reduced sensitivity of lymphocyte beta-adrenergic receptors in migraine.

    abstract::Cyclic AMP (CAMP) accumulation induced by isoproterenol (IP) and forskolin in intact lymphocytes was determined in 12 patients with migraine and 12 healthy controls. Our data showed that IP CAMP accumulation (8.20 + 1.08 Pmol/million cells) was significantly (P = 0.033) lower than accumulation in the controls (14.39 +...


    pub_type: 杂志文章


    authors: Kuritzky A,Bennet E,Hering R,Ebstein R

    更新日期:1993-04-01 00:00:00

  • Understanding the patient with migraine: the evolution from episodic headache to chronic neurologic disease. A proposed classification of patients with headache.

    abstract::Traditionally, episodic primary headache disorders are characterized by a return of preheadache (normal) neurologic function between episodes of headache. In contrast, patients with chronic headache often do not return to normal neurologic function between headache attacks. This article proposes that the evolution fro...


    pub_type: 杂志文章


    authors: Cady RK,Schreiber CP,Farmer KU

    更新日期:2004-05-01 00:00:00

  • Reading problems in adult chronic headache sufferers.

    abstract::In a questionnaire survey we determined the prevalence of problems with reading, at present as well as in the past, in adult chronic headache sufferers as compared with age- and sex-matched controls. The reading problems inquired about were those with reading in general, reading quickly, prolonged reading and reading ...


    pub_type: 杂志文章


    authors: Cremins JJ,Spierings EL,Meltzer LJ,Messinger HB,Lebbink J

    更新日期:1991-04-01 00:00:00

  • Body mass index and adult weight gain among reproductive age women with migraine.

    abstract:OBJECTIVE:To evaluate the cross-sectional relationship between migraine and pregravid obesity; and to assess the risk of adult weight gain among women with history of a pediatric diagnosis of migraine. BACKGROUND:Obesity, comorbid with pain disorders including migraine, shares common pathophysiological characteristics...


    pub_type: 杂志文章,多中心研究


    authors: Vo M,Ainalem A,Qiu C,Peterlin BL,Aurora SK,Williams MA

    更新日期:2011-04-01 00:00:00

  • Respiratory sinus arrhythmia in cluster headache syndrome.

    abstract::Respiratory sinus arrhythmia is regarded as indicative of cardiac vagal integrity. A ratio of the longest R-R interval to the shortest R-R interval during deep breathing test (E:I ratio) was calculated in controls (n = 49), cluster headache (n = 33) and CPH (n = 4) patients. E:I ratio decreased with age but was not de...


    pub_type: 杂志文章


    authors: Kruszewski P

    更新日期:1993-02-01 00:00:00

  • Increasing prevalence of headache in 7-year-old schoolchildren.

    abstract::Reports of increased prevalence of headache in adults and clinical impressions of similar trends in children prompted this epidemiological study on migraine and other headaches. The first stage was carried out in 1974 in children starting school, and the second stage in 1992 using the identical study design, the same ...


    pub_type: 杂志文章


    authors: Sillanpää M,Anttila P

    更新日期:1996-09-01 00:00:00

  • Reduction in the intensity of abortive migraine drug use during coumarin therapy.

    abstract:OBJECTIVE:To investigate the impact of coumarin therapy on migraine attack frequency. BACKGROUND:Sporadic case reports and clinical studies have described beneficial effects of coumarin therapy on migraine severity. DESIGN AND METHODS:A retrospective follow-up study based on a prescription database covering a populat...


    pub_type: 杂志文章


    authors: Rahimtoola H,Egberts AC,Buurma H,Tijssen CC,Leufkens HG

    更新日期:2001-09-01 00:00:00

  • Migraine Headache Day Response Rates and the Implications to Patient Functioning: An Evaluation of 3 Randomized Phase 3 Clinical Trials of Galcanezumab in Patients With Migraine.

    abstract:OBJECTIVE:This post hoc study investigated the relationship between patient response in terms of migraine headache day reduction and patient-reported outcomes of health-related quality of life (HRQoL) and disability categories. BACKGROUND:Migraine causes considerable disease-related disability and negatively impacts H...


    pub_type: 杂志文章


    authors: Ford JH,Kurth T,Starling AJ,Ayer DW,Wietecha LA,Port MD,Rettiganti M,Ruff DD

    更新日期:2020-11-01 00:00:00

  • Rizatriptan tablet versus wafer: patient preference.

    abstract::After taking both conventional oral rizatriptan tablets and oral disintegrating rizatriptan tablets in the treatment of migraine with or without aura, patients were permitted to select their formulation preference. All adult patients who had requested continuation of rizatriptan during a 6-month period were included i...


    pub_type: 杂志文章


    authors: Adelman JU,Mannix LK,Von Seggern RL

    更新日期:2000-05-01 00:00:00

  • The Course of Headache in Patients With Moderate-to-Severe Headache Due to Aneurysmal Subarachnoid Hemorrhage: A Retrospective Cross-Sectional Study.

    abstract:OBJECTIVES:The purpose of this study was to evaluate the course of headache in patients with moderate-to-severe headache due to aneurysmal subarachnoid hemorrhage (aSAH) and to identify its predisposing factors. BACKGROUND:Little is known about the long-term course of headache in patients with aSAH. METHODS:Since Sep...


    pub_type: 杂志文章


    authors: Hong CK,Joo JY,Kim YB,Shim YS,Lim YC,Shin YS,Chung J

    更新日期:2015-07-01 00:00:00

  • Pathophysiology of chronic migraine and mode of action of preventive medications.

    abstract::Evidence has accumulated in recent years indicating structural, physiologic, and biochemical alterations in the brain of patients with chronic migraine (CM). Altered pharmacologic responses to opioids and other analgesics have also been reported. Structural or morphologic changes include reduced cortical gray matter o...


    pub_type: 杂志文章


    authors: Mathew NT

    更新日期:2011-07-01 00:00:00

  • Patients with chronic tension-type headache demonstrate increased mechano-sensitivity of the supra-orbital nerve.

    abstract:OBJECTIVE:This study aimed to establish whether increased sensitivity to mechanical stimuli is present in neural tissues in chronic tension-type headache (CTTH). BACKGROUND:Muscle hyperalgesia is a common finding in CTTH. No previous studies have investigated the sensitivity of peripheral nerves in patients with CTTH....


    pub_type: 临床试验,杂志文章


    authors: Fernández-de-Las-Peñas C,Coppieters MW,Cuadrado ML,Pareja JA

    更新日期:2008-04-01 00:00:00

  • Differences in Topographical Pressure Pain Sensitivity Maps of the Scalp Between Patients With Migraine and Healthy Controls.

    abstract:OBJECTIVE:To investigate differences in topographical pressure pain sensitivity maps of the scalp between patients with migraine and healthy controls considering the chronicity (episodic/chronic) and side (strictly unilateral/bilateral) of the symptoms. BACKGROUND:It seems that the trigeminal area is sensitized in mig...


    pub_type: 杂志文章


    authors: Barón J,Ruiz M,Palacios-Ceña M,Madeleine P,Guerrero ÁL,Arendt-Nielsen L,Fernández-de-Las-Peñas C

    更新日期:2017-02-01 00:00:00

  • Fasting headache: a review of the literature and new hypotheses.

    abstract::Headache is a common disorder in the general population. It is often highly debilitating for the people affected and highly costly to society. Although we know much about primary headaches, little is known about secondary headaches which, however,are a frequent occurrence in the general population. A study conducted o...


    pub_type: 杂志文章,评审


    authors: Torelli P,Evangelista A,Bini A,Castellini P,Lambru G,Manzoni GC

    更新日期:2009-05-01 00:00:00

  • Unilateral black hairy tongue in trigeminal neuralgia.

    abstract::Unilateral hairlike discoloration of the tongue is described in a patient with ipsilateral mandibular division trigeminal neuralgia. This unusual physical sign coincided with the patient's painful trigger zone and was attributed to hypertrophy of keratinized filiform papillae, where guarded avoidance of mechanical sti...


    pub_type: 杂志文章


    authors: Cheshire WP Jr

    更新日期:2004-10-01 00:00:00

  • Headache and electroconvulsive therapy.

    abstract::While headache is a documented side effect of electroconvulsive therapy (ECT), there is little information on this phenomenon. Studies of the mechanisms of ECT as a treatment for depression indicate that alterations in serotonergic neurotransmission appear to be related to its efficacy. While ECT and many of the antid...


    pub_type: 杂志文章


    authors: Weiner SJ,Ward TN,Ravaris CL

    更新日期:1994-03-01 00:00:00

  • Transient Global Amnesia Triggered by Migraine in a French Tertiary-Care Center: An 11-Year Retrospective Analysis.

    abstract:OBJECTIVE:The etiology of transient global amnesia (TGA) remains unclear, and flow disturbances in the mesial temporal lobes secondary to venous congestion have been proposed as a potential cause. The occurrence of TGA during a migraine attack is a rare condition. METHODS:This 11-year retrospective study in one French...


    pub_type: 杂志文章


    authors: Donnet A

    更新日期:2015-06-01 00:00:00

  • Disability in chronic migraine patients with medication overuse: treatment effects at 1-year follow-up.

    abstract:OBJECTIVE:To determine (1) the clinical course of a sample of chronic migraine patients with drug overuse 6 and 12 months following in-patient treatment and (2) whether functional impairment, assessed by the Migraine Disability Assessment (MIDAS) questionnaire, improved upon treatment. BACKGROUND:Patients with chronic...


    pub_type: 杂志文章


    authors: Grazzi L,Andrasik F,D'Amico D,Usai S,Kass S,Bussone G

    更新日期:2004-07-01 00:00:00

  • Internalizing Symptoms in Pediatric Migraine: A Systematic Review Protocol.

    abstract:OBJECTIVES:The primary objective of the proposed systematic review is to determine if there is an association between internalizing disorders and symptoms (ie, subclinical symptoms) and migraine in children and adolescents. METHODS:We will perform a peer-reviewed Peer Review of Electronic Search Strategies search of M...


    pub_type: 杂志文章


    authors: Falla K,Ronksley P,Noel M,Orr SL

    更新日期:2020-04-01 00:00:00

  • Persistent trigeminal artery causing "double" neurovascular conflict.

    abstract::We report the case of a 73-year-old woman who presented with right VI nerve palsy and homolateral atypical trigeminal neuralgia; standard neuroradiological investigation of orbital/retroorbital regions and intracranial arteries excluded the most commonly demonstrable underlying causes while brain magnetic resonance (T...


    pub_type: 杂志文章


    authors: Clerici AM,Merlo P,Rognone F,Noce M,Rognone E,Bono G

    更新日期:2009-03-01 00:00:00