Migraine without aura and reproductive life events: a clinical epidemiological study in 1300 women.

Abstract:

:A retrospective study was conducted on 1300 women suffering from migraine without aura referred to the Headache Centers of Parma and Pavia from 1984 to 1990. All the data concerning their reproductive life, and the modifications induced by it on the course of headache were obtained from record-charts. Migraine frequently started at menarche (10.7%); in 60% of cases the migraine attacks occurred mostly or exclusively in the perimenstrual period, in 67% of cases disappeared during pregnancy, and in 24.1% significantly (P < 0.0001) worsened with "pill" intake. This study also designated a migraine subgroup which is more influenced by changes in sexual hormones, i.e. migraine with onset at menarche. This form of migraine shows more frequently a menstrual periodicity, and usually improves during pregnancy. Furthermore, menstrual migraine patients show social and cultural characteristics with distinguish them from other women.

journal_name

Headache

journal_title

Headache

authors

Granella F,Sances G,Zanferrari C,Costa A,Martignoni E,Manzoni GC

doi

10.1111/j.1526-4610.1993.hed3307385.x

subject

Has Abstract

pub_date

1993-07-01 00:00:00

pages

385-9

issue

7

eissn

0017-8748

issn

1526-4610

journal_volume

33

pub_type

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