Abstract:
:Sex-determination genes are among the most fluid features of the genome in many groups of animals. In some taxa the master sex-determining gene moves frequently between chromosomes, whereas in other taxa different genes have been recruited to determine the sex of the zygotes. There is a well developed theory for the origin of stable and highly dimorphic sex chromosomes seen in groups such as the eutherian mammals. In contrast, the evolutionary lability of genetic sex determination in other groups remains largely unexplained. In this theoretical study, we show that an autosomal gene under sexually antagonistic selection can cause the spread of a new sex-determining gene linked to it. The mechanism can account for the origin of new sex-determining loci, the transposition of an ancestral sex-determining gene to an autosome, and the maintenance of multiple sex-determining factors in species that lack heteromorphic sex chromosomes.
journal_name
Naturejournal_title
Natureauthors
van Doorn GS,Kirkpatrick Mdoi
10.1038/nature06178subject
Has Abstractpub_date
2007-10-18 00:00:00pages
909-12issue
7164eissn
0028-0836issn
1476-4687pii
nature06178journal_volume
449pub_type
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