Worldwide childhood type 1 diabetes incidence--what can we learn from epidemiology?

abstract：BACKGROUND:Pediatric diabetes clinics around the world rapidly adapted care in response to COVID-19. We explored provider perceptions of care delivery adaptations and challenges for providers and patients across nine international pediatric diabetes clinics. METHODS:Providers in a quality improvement collaborative com...

journal_title：Pediatric diabetes

authors： Cristello Sarteau A,Souris KJ,Wang J,Ramadan AA,Addala A,Bowlby D,Corathers S,Forsander G,King B,Law JR,Liu W,Malik F,Pihoker C,Seid M,Smart C,Sundberg F,Tandon N,Yao M,Headley T,Mayer-Davis E

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:Patient-reported outcomes have received increased attention as treatment outcomes and indicators of wellbeing. A1c has been criticized as lacking patient-centered relevance because individuals are often unaware of their A1c, and studies also often fail to show a benefit of intensive control on quality of life...

journal_title：Pediatric diabetes

authors： Kane NS,Hoogendoorn CJ,Commissariat PV,Schulder TE,Gonzalez JS

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To explore the outcomes of monthly video consultations for children with diabetes. METHODS:The Virtual Outpatient Diabetes Clinic for Children and Youth (VIDIKI) was a 6-month multicenter controlled clinical trial followed by an extension phase. The 240 participants (1-16 years), all using a CGM, were quasi-...

journal_title：Pediatric diabetes

authors： von Sengbusch S,Eisemann N,Mueller-Godeffroy E,Lange K,Doerdelmann J,Erdem A,Menrath I,Bokelmann J,Krasmann M,Kaczmarczyk P,Bertram B,Hiort O,Katalinic A,Frielitz FS

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:The Environmental Determinants of Diabetes in the Young (TEDDY) study is designed to identify environmental exposures triggering islet autoimmunity and type 1 diabetes (T1D) in genetically high-risk children. We describe the first 100 participants diagnosed with T1D, hypothesizing that (i) they are diagnosed ...

journal_title：Pediatric diabetes

authors： Elding Larsson H,Vehik K,Gesualdo P,Akolkar B,Hagopian W,Krischer J,Lernmark Å,Rewers M,Simell O,She JX,Ziegler A,Haller MJ,TEDDY Study Group.

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of initial insulin dosage on blood glucose (BG) dynamics, β-cell protection, and oxidative stress in type 1 diabetes mellitus. METHODS:Sixty newly diagnosed type 1 diabetes mellitus patients were randomly assigned to continuous subcutaneous insulin infusions of 0.6 ± 0.2 IU/kg/d (gr...

journal_title：Pediatric diabetes

authors： Wang Y,Gong C,Cao B,Meng X,Wei L,Wu D,Liang X,Li W,Liu M,Gu Y,Su C

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Studies indicate general psychological stress plays a role in the glycemic control of individuals with type 1 diabetes mellitus (T1DM). Disease-specific rather than general measures may be more closely related to measures of health outcomes. Therefore, measurement of diabetes-related stress is needed to advan...

journal_title：Pediatric diabetes

authors： Delamater AM,Patiño-Fernández AM,Smith KE,Bubb J

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To describe insulin pump use by youth since introduction of universal funding in Ontario, Canada and to explore the relationship between pump use and pediatric diabetes center characteristics and the relationship between discontinuation and center and patient characteristics. RESEARCH DESIGN AND METHODS:Obse...

journal_title：Pediatric diabetes

authors： Shulman R,Stukel TA,Miller FA,Newman A,Daneman D,Guttmann A

更新日期：2017-02-01 00:00:00

abstract：:Persistent 'IgE-mediated' insulin allergy (type 1 allergy) (1), unresponsive to changes in insulin type or the use of antihistamines, necessitates desensitization. A number of case reports (2-7) and recent reviews (8, 9) have demonstrated that desensitization can be achieved with continuous subcutaneous insulin infusi...

journal_title：Pediatric diabetes

authors： Neville KA,Verge CF,Wainstein BK,Woodhead HJ,Ziegler JB,Walker JL

更新日期：2008-08-01 00:00:00

abstract：:This review highlights the evidence of linking small for gestational age (SGA) with metabolic/cardiovascular disturbances (dysmetabolic syndrome) in later life. The metabolic and cardiovascular complications associated with in utero undernutrition have been identified during the past 10 yr. Reduced fetal growth is ind...

journal_title：Pediatric diabetes

authors： Levy-Marchal C,Jaquet D

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Type 2 Diabetes (T2DM) is increasing in childhood especially among females and South-Asians. Our objective was to report outcomes from a national cohort of children and adolescents with T2DM 1 year following diagnosis. METHODS:Clinician reported, 1-year follow-up of a cohort of children (<17 years...

journal_title：Pediatric diabetes

authors： Candler TP,Mahmoud O,Lynn RM,Majbar AA,Barrett TG,Shield JPH

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:It is unknown whether measurement site of visceral adipose tissue (VAT) influences the relationship between VAT and associated health risk in youth and if so, whether ethnic differences exist in this relationship. We examined the influence of the measurement site of VAT on the relationships between VAT and me...

journal_title：Pediatric diabetes

authors： Lee S,Kuk JL,Kim Y,Arslanian SA

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine the degree of left ventricular (LV) dysfunction and its determinants in adolescents with type 2 diabetes (T2D). We hypothesized that adolescents with T2D would display impaired LV diastolic function and that these cardiovascular complications would be exacerbated in youth exposed...

journal_title：Pediatric diabetes

authors： Guillemette L,Dart A,Wicklow B,Dolinsky VW,Cheung D,Jassal DS,Sellers EAC,Gelinas J,Eves ND,Balshaw R,Agarwal P,Duhamel TA,Gordon JW,McGavock JM

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Incidence rates of type 1 diabetes have long been on the rise across the globe, however, there is emerging evidence that the rate of rise may be slowing. The objective of this study was to describe trends in the incidence and prevalence of type 1 diabetes in a sample of Canadian children and yo...

journal_title：Pediatric diabetes

authors： Fox DA,Islam N,Sutherland J,Reimer K,Amed S

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To compare outcomes of diabetic ketoacidosis (DKA) 6 yrs before and 6 yrs after changing rehydration fluids from ½ normal saline to Lactated Ringer's and decreasing the total intended fluid volume administered in the first 24 hrs from 3500 mL/m(2) /d to ≤ 2500 mL/m(2) /d at Texas Children's Hospital (TCH) in ...

journal_title：Pediatric diabetes

authors： Hsia DS,Tarai SG,Alimi A,Coss-Bu JA,Haymond MW

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and carotid intima-medial thickness (CIMT) in Chinese youth and adolescents with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS:Ninety-eight subjects aged 10-24 yr with newly-diagnosed T2DM...

journal_title：Pediatric diabetes

authors： Li X,Deng YP,Yang M,Wu YW,Sun SX,Sun JZ

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Several intervention studies have convincingly demonstrated the importance of good glycemic control to avoid long-term diabetic complications, but the importance of other risk factors remains controversial. We previously reported a markedly reduced incidence of severe retinopathy and nephropathy during the p...

journal_title：Pediatric diabetes

authors： Nordwall M,Arnqvist HJ,Bojestig M,Ludvigsson J

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Obesity and pubertal insulin resistance worsen cardiovascular (CV) risk factors in youth. It is unclear how the relationships of obesity and insulin resistance with CV risk compare to adults. SUBJECTS AND METHODS:We evaluated 66 pubertal youth (mean ± SD: age 14.2 ± 2.0 years, body mass index [BMI] 36.6 ± 6...

journal_title：Pediatric diabetes

authors： RISE Consortium.

更新日期：2019-11-01 00:00:00

abstract：:The aim of this study was to examine secular trends in the incidence of type 1 diabetes in children aged 0-14 yr in Hungary over the period 1989-2009. Newly diagnosed children with type 1 diabetes aged 0-14 yr in Hungary were prospectively registered from 1989 to 2009. Primary ascertainment of cases was by prospective...

journal_title：Pediatric diabetes

authors： Gyurus EK,Patterson C,Soltesz G,Hungarian Childhood Diabetes Epidemiology Group.

更新日期：2012-02-01 00:00:00

abstract：AIMS:Children with type 1 diabetes (T1D) risk and islet autoantibodies are recruited to a secondary prevention study. The aims were to determine metabolic control in relation to human leukocyte antigen (HLA) genetic risk and islet autoantibodies in prepubertal children. METHODS:In 47 healthy children with GADA and at ...

journal_title：Pediatric diabetes

authors： Andersson C,Carlsson A,Cilio C,Cedervall E,Ivarsson SA,Jonsdottir B,Jönsson B,Larsson K,Neiderud J,Lernmark A,Elding Larsson H,DiAPREV-IT Study Group.

更新日期：2013-08-01 00:00:00

abstract：:Neonatal diabetes mellitus is a rare (1/400 000 newborns) but potentially devastating condition, which may be transient or permanent; typical symptoms occur within the first 4 wk of life. The transient form is a developmental insulin production disorder that resolves postnatally. Fifty to 60% of cases can be seen as t...

journal_title：Pediatric diabetes

authors： Goksen D,Darcan S,Coker M,Aksu G,Yildiz B,Kara S,Kültürsay N

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:To investigate if maternal diet during pregnancy is associated with occurrence of islet autoimmunity (IA) in the offspring. METHODS:Of 21 700 infants invited to the All Babies in South-east Sweden (ABIS) study, 16 004 screening questionnaires, including a 22-item food frequency questionnaire (FFQ) regarding ...

journal_title：Pediatric diabetes

authors： Brekke HK,Ludvigsson J

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To determine the roles of complement C4A and C4B gene copy-number variations and their plasma protein concentrations in residual insulin secretion and loss of pancreatic β-cell function in new-onset type 1 diabetes (T1D) patients. METHODS:We studied 34 patients of European ancestry with new-onset T1D, aged b...

journal_title：Pediatric diabetes

authors： Kingery SE,Wu YL,Zhou B,Hoffman RP,Yu CY

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:High serum uric acid (SUA) levels are present in patients with metabolic syndrome (MetS), when the latter is associated with endothelial dysfunction, inflammation, and hypertension. This increase in SUA levels may have a key role in cardiovascular diseases. OBJECTIVE:We aim to quantify the differences in in...

journal_title：Pediatric diabetes

authors： Valle M,Martos R,Cañete MD,Valle R,van Donkelaar EL,Bermudo F,Cañete R

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Children who inject insulin need clear guidelines as to the length of needle best for them. We studied the distance from surface to muscle in children in order to make needle choices which are evidence-based. METHODS:One hundred one children with type 1 diabetes were divided into three groups according to a...

journal_title：Pediatric diabetes

authors： Lo Presti D,Ingegnosi C,Strauss K

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Mechanisms underlying the role of non-human leukocyte antigen (HLA) genetic risk variants in type 1 diabetes (T1D) are poorly understood. We aimed to test the association between methylation and non-HLA genetic risk. METHODS:We conducted a methylation quantitative trait loci (mQTL) analysis in a nested case-...

journal_title：Pediatric diabetes

authors： Carry PM,Vanderlinden LA,Johnson RK,Dong F,Steck AK,Frohnert BI,Rewers M,Yang IV,Kechris K,Norris JM

更新日期：2020-06-01 00:00:00

abstract：:Slow wave sleep (SWS), or deep sleep, is thought to be the most restorative stage of sleep and may be of a particular interest in the pathophysiology of obesity. The aim of this study was to investigate differences in sleep architecture based on body mass index (BMI) among a pediatric population with type 1 diabetes m...

journal_title：Pediatric diabetes

authors： Elrokhsi SH,Bluez GP,Chin CN,Wheeler MD,Silva GE,Perfect MM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Insulin pump therapy is well established in the treatment of children and adolescents with type 1 diabetes. Most studies focus on outcome parameters like hemoglobin A1c (HbA1c), hypoglycemia, and quality of life, whereas few reports address patients who discontinue pump therapy. OBJECTIVE:This survey focuse...

journal_title：Pediatric diabetes

authors： Hofer SE,Heidtmann B,Raile K,Fröhlich-Reiterer E,Lilienthal E,Berghaeuser MA,Holl RW,DPV-Science-Initiative and the German working group for insulin pump treatment in pediatric patients.

更新日期：2010-03-01 00:00:00

abstract：:There are two peaks in the distribution of the age of onset of type 1 diabetes mellitus (T1DM)--the first in early childhood and the second at the time of puberty. Although T1DM results from the interaction of genetic and non-genetic factors, it has not been established which factors contribute to the bimodal distribu...

journal_title：Pediatric diabetes

authors： Felner EI,Klitz W,Ham M,Lazaro AM,Stastny P,Dupont B,White PC

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To evaluate an ambulatory, portable prototype, overnight automated closed-loop (CL) system and to explore optimal time of CL initiation. METHODS:We performed a randomized crossover study and compared automated overnight glucose control started at the time of an evening-meal or at bedtime. Eight young people ...

journal_title：Pediatric diabetes

authors： Elleri D,Allen JM,Biagioni M,Kumareswaran K,Leelarathna L,Caldwell K,Nodale M,Wilinska ME,Acerini CL,Dunger DB,Hovorka R

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The incidence of type 1 diabetes mellitus (T1DM) among children and adolescents increased during the last 50 yr. The T1DM incidence in Croatia was 8.87/100.000/yr over 1995-2003, with an annual increase of 9%, which placed Croatia among countries with moderate risk for T1DM. AIM:To investigate incidence rat...

journal_title：Pediatric diabetes

authors： Rojnic Putarek N,Ille J,Spehar Uroic A,Skrabic V,Stipancic G,Krnic N,Radica A,Marjanac I,Severinski S,Svigir A,Bogdanic A,Dumic M

更新日期：2015-09-01 00:00:00