Abstract:
BACKGROUND:The incidence of type 1 diabetes mellitus (T1DM) among children and adolescents increased during the last 50 yr. The T1DM incidence in Croatia was 8.87/100.000/yr over 1995-2003, with an annual increase of 9%, which placed Croatia among countries with moderate risk for T1DM. AIM:To investigate incidence rates and trends of T1DM from 2004 to 2012 in 0 to 14-yr-old Croatian children, and to compare the results with previous studies in Croatia and other European countries. METHODS:T1DM crude incidence rates are estimated for the entire group and three subgroups: 0-4, 5-9, and 10-14 yr. Standardized incidence is calculated using the method of direct standardization according to World Health Organization (WHO) standard world population. The incidence rates by gender, age groups, seasonality, and calendar year, and their interactions were analyzed using Poisson regression model. RESULTS:A total of 1066 cases were ascertained over 2004-2012. The standardized incidence was 17.23/100.000/yr (95% CI: 16.19-18.26), with no significant differences in incidence rates or trends between boys and girls. Statistically significant annual increase of 5.87% (p < 0.001) was found for the whole group, and for the subgroups 5-9 yr (6.82%; p < 0.001) and 10-14 yr (7.47%; p < 0.001). In the youngest subgroup (0-4 yr), annual increase was lower (2.43%; p = 0338) and not statistically significant. CONCLUSION:The incidence of childhood T1DM is increasing in Croatia, thus placing Croatia among countries with high risk for T1DM. The annual increment of 5.87% is considerably lower than 9.0% reported earlier, but still higher than the European average (3.9%). The increase in incidence ceased in youngest children.
journal_name
Pediatr Diabetesjournal_title
Pediatric diabetesauthors
Rojnic Putarek N,Ille J,Spehar Uroic A,Skrabic V,Stipancic G,Krnic N,Radica A,Marjanac I,Severinski S,Svigir A,Bogdanic A,Dumic Mdoi
10.1111/pedi.12197subject
Has Abstractpub_date
2015-09-01 00:00:00pages
448-53issue
6eissn
1399-543Xissn
1399-5448journal_volume
16pub_type
杂志文章abstract:OBJECTIVE:Mothers of youth with type 1 diabetes experience increased levels of stress and depression related to the burden of diabetes management, but the concept of diabetes distress, or distress linked specifically to diabetes and its management, has not been applied to mothers. The current study examined diabetes di...
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journal_title:Pediatric diabetes
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journal_title:Pediatric diabetes
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Pediatric diabetes
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doi:10.1046/j.1399-543x.2001.00000.x
更新日期:2001-03-01 00:00:00
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journal_title:Pediatric diabetes
pub_type: 已发布勘误
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doi:10.1111/j.1399-5448.2009.00601.x
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journal_title:Pediatric diabetes
pub_type: 杂志文章,评审
doi:10.1111/j.1399-5448.2007.00328.x
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:Dysglycemia is prevalent in cystic fibrosis (CF) but screening with annual oral glucose tolerance tests (OGTT) can be burdensome. We investigated alternate glycemic markers-hemoglobin A1c (HbA1c), 1,5-anhydroglucitol (1,5AG), fructosamine (FA), and glycated albumin (GA)-as screening tests for CF-related diabe...
journal_title:Pediatric diabetes
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journal_title:Pediatric diabetes
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journal_title:Pediatric diabetes
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journal_title:Pediatric diabetes
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更新日期:2006-10-01 00:00:00
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journal_title:Pediatric diabetes
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doi:10.1111/j.1399-5448.2008.00496.x
更新日期:2009-09-01 00:00:00
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journal_title:Pediatric diabetes
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更新日期:2017-08-01 00:00:00
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journal_title:Pediatric diabetes
pub_type: 杂志文章
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journal_title:Pediatric diabetes
pub_type: 杂志文章,评审
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更新日期:2004-03-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2006-08-01 00:00:00