Abstract:
:After a single injection of serum gonadotrophin (PMSG) at the dose of 15 IU/kg, i.m. into rams testosterone in the plasma of blood showed a significant rise between 4th and 7th day post-injection. At the same time (4th-7th day) the plasminogen activator activity (PAA) in seminal plasma was found to be increased, but the plasminogen activator inhibition (PAI) expressed against t-PA (anti-t-PA) showed an increase between 32nd and 46th day. In spermatozoa a marked increase of PAA was revealed between 32nd and 46th day post-injection, while an increase of PAI (anti-t-PA) was exhibited on the 74th day. Plasmin inhibition (PI) in seminal plasma and spermatozoa showed no change compared to controls. A positive correlation has been found between increased concentrations of testosterone and PAA or PAI (anti-t-PA) in spermatozoa and seminal plasma. The induced increase of PAA in spermatozoa under the effect of testosterone might be of physiological importance, since PAA is localized to sperm membranes and might participate in the whole process of fertilization.
journal_name
Andrologiajournal_title
Andrologiaauthors
Rekkas C,Belibasaki S,Taitzoglou I,Kokolis N,Smokovitis Adoi
10.1111/j.1439-0272.1991.tb02559.xsubject
Has Abstractpub_date
1991-07-01 00:00:00pages
273-8issue
4eissn
0303-4569issn
1439-0272journal_volume
23pub_type
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