Abstract:
:The acrosome is a secretory vesicle located in the sperm head. The acrosome reaction consists in the fusion of the sperm plasma membrane with the external acrosomal membrane. It has been observed that this reaction does not take place in spermatozoa incubated in cervical mucus, hydrogel that contains high concentrations of oestradiol in the peri-ovulatory period. The objective of the present study was to analyse the influence of oestradiol on the acrosome reaction in human spermatozoa to evaluate the possible inhibitory effect of this hormone. Spermatozoa were incubated in progesterone (10.1 nmol l(-1)); oestradiol plus progesterone (oestradiol at 840 pmol l(-1) and progesterone at 10.1 nmol l(-1)), oestradiol (840 pmol l(-1)) and control (without steroidal hormones) for 30 min, 60 min, 240 min and 24 h. The acrosome reaction was evaluated by stain with Hoechst 33258 and fluorescein isothiocyanate-conjugated Pisum sativum agglutinin lectin. Progesterone-incubated spermatozoa showed the highest percentage of acrosome reaction (P < 0.05). Spermatozoa incubated with oestradiol and oestradiol plus progesterone showed the lowest percentage of acrosome reaction. The present study demonstrates the inhibitory role of oestradiol on the acrosome reaction, stimulated by progesterone in human spermatozoa under physiological conditions.
journal_name
Andrologiajournal_title
Andrologiaauthors
Vigil P,Toro A,Godoy Adoi
10.1111/j.1439-0272.2007.00814.xsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
146-51issue
3eissn
0303-4569issn
1439-0272pii
AND814journal_volume
40pub_type
杂志文章相关文献
ANDROLOGIA文献大全abstract::In cases of azoospermia especially after vasectomy the investigation of the seminal sediment investigation is necessary. Exclusive on this way it is possible to find some side dispersed spermatozoa. The described case deals with a pregnancy about 48 days following vasectomy. Postoperative the sperm sediment investigat...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1984-07-01 00:00:00
abstract::Various nuclear sperm alterations are reported in patients with syndromic teratozoospermia; however, this has not been clearly identified yet in total polymorphic teratozoospermia. The aim of this study was to analyse sperm aneuploidy, DNA integrity and chromatin packaging in 45 infertile patients with total polymorph...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13252
更新日期:2019-06-01 00:00:00
abstract::Corpus cavernosum smooth muscle cells (CCSMCs) are important functional cells for penile erection. We evaluated the effect of transforming growth factor β1 (TGFβ1) and hepatocyte growth factor (HGF) on the viability and apoptosis of CCSMCs in vitro. CCSMCs from healthy male Sprague Dawley rats were randomly divided in...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12372
更新日期:2015-11-01 00:00:00
abstract::The acrosome reaction of human spermatozoa was induced by changes of temperature. Spermatozoa were collected from fertile donors and a patient group, and selected by the "swim-up" method. The spermatozoa were treated in two different ways: Protocol I: 24 hours at room temperature followed by additional incubation at 3...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1991.tb02537.x
更新日期:1991-05-01 00:00:00
abstract::Infertility is a major health problem which affects approximately 22% of married couples in reproductive age. Chromosomal defects are the most common genetic abnormalities in infertile men, with an incidence of cytogenetic abnormalities ranging from 2.1% to 15.5%. We describe here the clinical and cytogenetic studies ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12120
更新日期:2014-05-01 00:00:00
abstract::On the basis of the concept that immunogenetic factors play a role in the incidence of unexplained male infertility, the so-called idiopathic infertility, HLA antigen analyses were performed for (1) azoospermia cases among the infertile males diagnosed by testicular biopsies as having germ cell aplasia and (2) unexpla...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1980.tb00638.x
更新日期:1980-07-01 00:00:00
abstract::Multiple number of techniques and devices have been described concerning circumcision method so far. One of them is thermocautery device, and it has been widely used. Although there is controversy that the penis may be damaged due to the heat generated during the use of the device, not enough histopathological studies...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13968
更新日期:2021-01-09 00:00:00
abstract::Previous studies have shown that alpha1-adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of the seminal fluid in normal...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2012.01324.x
更新日期:2013-04-01 00:00:00
abstract::This study aimed to evaluate the effect of N-acetyl cysteine on the male reproductive system and consensus and classification of data found from previous studies. It is undeniable that N-acetyl cysteine as a powerful antioxidant compound can medicate many diseases such as cardiovascular, kidney, liver and reproductive...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/and.13898
更新日期:2021-02-01 00:00:00
abstract::Previous studies showed that exposure to stress or nicotine induced reproductive impairment in male rats. Here, we assessed the effect of an antioxidant (vitamin E) on nicotine-, stress- and nicotine + stress-induced reproductive impairment in male rats. Forty-eight male albino Wistar rats were divided into eight grou...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13050
更新日期:2018-09-01 00:00:00
abstract::The RNA has been located and proportioned by a spectrophotometric method which absorbs the ultra-violet light. The technique used allows us to execute punctual dosage into the spermatozoon's tail. Each of these punctual dosages makes us realise the RNA localisation; and the sum of these dosages makes us realise the to...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is an intractable disease. This study aimed to assess the efficacy of cryotherapy in the therapy of CP/CPPS. One hundred and seventy-two patients with CP/CPPS were randomised to receive cryotherapy or sham cryotherapy. The follow-up assessments were done at we...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13920
更新日期:2020-12-24 00:00:00
abstract::This study was planned to determine the relationship between semen quality parameters and the levels of biochemical constituents of seminal plasma of Teddy (Capra hircus) buck semen. For this purpose, semen ejaculates were collected from five mature healthy Teddy bucks. All the experimental bucks were kept under natur...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12940
更新日期:2018-04-01 00:00:00
abstract::Morphologically normal spermatozoa from groups of men attending the infertility clinic with normal density and motility had subcellular elemental composition measurements from various parts of the spermatozoa compared with anatomically similar spermatozoa from semen with marked oligo- or asthenozoospermia. In the two ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1988.tb01060.x
更新日期:1988-05-01 00:00:00
abstract::Chronic prostatitis/chronic pelvic pain syndrome (CP⁄CPPS) is the prostate gland inflammation characterised as genitourinary pain in the pelvic region. The rat experimental autoimmune prostatitis (EAP) was achieved to mimic CP⁄CPPS. The expressions of transient receptor potential vanilloid 1 (TRPV1) in the prostate, b...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13302
更新日期:2019-09-01 00:00:00
abstract::Maturation arrest (MA) of spermatogenesis is diagnosed on histology as interruption of spermatogenesis before the final stage without impairment of Sertoli or Leydig cells. It is considered a condition of irreversible or absolute infertility. Varicocele, which represents impairment in the testicular venous drainage sy...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2010.01083.x
更新日期:2010-12-01 00:00:00
abstract::Androgen insensitivity syndrome (AIS) is an X-linked disorder due to mutations of androgen receptor (AR) gene. Various AR mutations have been identified, and the characterisation of these mutations greatly facilitates our understanding of AR structure-function. In this study, we have analysed an AR missense mutation (...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2011.01219.x
更新日期:2012-05-01 00:00:00
abstract::Epididymal sperm reserve was determined in 6 sexually mature fertile buffalo-bulls having normal process of spermatogenesis. The relative distribution of spermatozoa in the caput, corpus and cauda epididymidis averaged 5.42, 0.75 and 11.45 billion respectively. Total epididymal sperm reserve per bull averaged 36.2 bil...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1978.tb03076.x
更新日期:1978-11-01 00:00:00
abstract::Two esterases previously identified in seminal plasma, on the basis of their electrophoretic mobility, immunogenicity and sensitivity to organophosphorus esters were detected in various human external secretions and leucocyte extracts. alpha-Esterase was found to be abundant in urine and milk whereas this enzyme occur...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1976.tb01650.x
更新日期:1976-01-01 00:00:00
abstract::Varicocele is the most common cause of male infertility. Several theories have been proposed to explain how varicocele induces infertility. The role of epididymis in male infertility is not fully well established. Fibrinogen-like protein 2 is one of serine proteases and is a potent coagulant in membranous form and imm...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13626
更新日期:2020-07-01 00:00:00
abstract::Twenty infertile patients with normal tubal patency were inseminated intraperitoneally (11 once, seven twice, and two three times) with spermatozoa (mean 14 x 10(6), range 0.6-48 x 10(6)) prepared by the standard swim-up technique. The occurrence of immunization to spermatozoa was looked for by the Gelatin Agglutinati...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1993.tb02673.x
更新日期:1993-01-01 00:00:00
abstract::In order to correlate functional and biochemical parameters, frozen bovine sperm samples presenting diverse motility were studied. Specimens collected from four bulls (A, B, C and D) were graded according to motile spermatozoa percentage and vigour, regarding the sample from bull A as highest motility, those from bull...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1997.tb03146.x
更新日期:1997-01-01 00:00:00
abstract::Interchromosomal effect is a controversial phenomenon postulating that during gametogenesis of translocation carriers, aside from the unbalanced segregation of chromosomes involved in the translocation, other, structurally normal chromosomes might also be affected and segregated abnormally. Here, we present a balanced...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/and.13805
更新日期:2021-02-01 00:00:00
abstract::Sperm motility and vitality are decreased in male genital tract infection. Uropathogenic Escherichia coli (UPEC) are frequently associated with sperm parameter loss, but there are no reports to date regarding the effects of different E. coli isolates on human spermatozoa. The aim of this work was to compare the effect...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12167
更新日期:2014-10-01 00:00:00
abstract::The mammalian target of rapamycin (TOR) has been implicated in the control of different stressors, growth factors, nutrients and hormones, participating in the control of key cellular functions. Controlling this many pathways poses mTOR signalling as a potential new target in new treatment strategies for multiple canc...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12504
更新日期:2016-08-01 00:00:00
abstract::Testicular tissue and sex hormones are sensitive to the anabolic steroids (oxymetholone/OM) due to increased free radical damage and hormonal changes. The Nasturtium officinale L. have various antioxidant compounds. The aim of the present study was to investigate N. officinale effect on OM-induced oxidative injury in ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13294
更新日期:2019-08-01 00:00:00
abstract::In fertile men, the majority of epididymal spermatozoa acquire the potential to fertilize (assessed with sperm function assays) on passage into the corpus and cauda regions of the epididymis. Although secretions of the epididymal epithelium are clearly important for sperm maturation and survival, their role in this pr...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0272.1998.tb01165.x
更新日期:1998-08-01 00:00:00
abstract::The aim of this study was to evaluate the effect of Lepidium meyenii (maca) in chemically and physically subfertile mice. After 35 days, the following groups of mice were evaluated: control, sham, chemical subfertility, chemical subfertility-maca-supplemented, physical subfertility, physical subfertility-maca-suppleme...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12682
更新日期:2016-10-01 00:00:00
abstract::Tramadol, one of the most commonly abused drugs in Middle East, impacts spermatogenesis and disturbs reproductive hormones in animal studies. We aimed to investigate tramadol impact on sperm quality and on levels of testosterone, prolactin and gonadotropins, in tramadol abusers (n = 30) to age-matched control (n = 30)...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13026
更新日期:2018-08-01 00:00:00
abstract::Penile amputation is an uncommon condition for which immediate surgical replantation is warranted. This work aimed to represent intervention and management for an amputated penis by replantation and reconstruction. A 23-year-old man presented with traumatic penile amputation for 2 h where the penile proximal part was ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2009.00925.x
更新日期:2009-08-01 00:00:00