Association of IgA secretory component sialylation with leucocytospermia of infertile men - a pilot study.

Abstract:

:The aim of our pilot study was to check whether the differences in IgA secretory component (SC) sialylation are associated with leucocytospermia. In normozoospermic and leucocytospermic seminal plasmas, 78-kDa and 63-kDa SC immunoreactive bands were observed. The SC sialylation was analysed by lectin blotting, using sialo-specific lectins MAA (Maackia amurensis agglutinin) and SNA (Sambucus nigra agglutinin). Specific reactivity of 63-kDa SC with MAA and SNA was higher than 78-kDa SC in both analysed seminal groups. The analysis of seminal SC sialylation might be a valuable diagnosis tools for the evaluation of fertility problems related with leucocytospermia.

journal_name

Andrologia

journal_title

Andrologia

authors

Kratz EM,Ferens-Sieczkowska M

doi

10.1111/and.12213

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

1200-2

issue

10

eissn

0303-4569

issn

1439-0272

journal_volume

46

pub_type

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