Abstract：
:In the last decades, relevant efforts have been made to reduce the cancer incidence in the European Union. The prevention programmes against cancer have obtained satisfactory results except for colorectal cancer (CRC). Identification of risk factors is primordial to plan preventive strategies for CRC. We hypothesize that shellfish consumption is increasing CRC incidence. DSP toxins, present in some seafood products, seem to behave like tumour agents. There are no relevant studies on real health-risk of consuming DSP toxins, just some experimental and ecological evidence. Preventive interventions for reducing CRC risk must be approached through the collaboration of governmental, health and environmental sectors as a single regulatory agency. Sometimes, shellfish accumulates diarrhetic shellfish poisoning (DSP) toxins (i.e. okadaic acid and its derivatives) which provoke a gastrointestinal illness (DSP syndrome). Furthermore, DSP toxins are tumour promoters that could increase CRC risk. The current regulation about level of DSP toxins in shellfish meat is only centred on reduction of the gastrointestinal symptoms. Unfortunately, legal levels of DSP toxins in shellfish are enough to increase CRC risk. A review of legislation on DSP toxins is urgent.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Manerio E,Rodas VL,Costas E,Hernandez JMdoi
10.1016/j.mehy.2007.03.041subject
Has Abstractpub_date
2008-01-01 00:00:00pages
409-12issue
2eissn
0306-9877issn
1532-2777pii
S0306-9877(07)00349-0journal_volume
70pub_type
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