Abstract：
:Most of the evidence of formation of amblyopia is derived traditionally from electrophysiological studies. Recently, there have been many discoveries from genetics, histopathology, biochemistry, immunology and interventional studies. On the basis of evidence gathered in the last five years, the various types of amblyopia (strabismic and non-strabismic amblyopia) can be seen not only as disturbance of the development of the visual system at different points but as basically different pathologic processes. It is postulated here that strabismic amblyopia is initiated as a maladaptive differentiation in the ocular dominance columns, whereas the non-strabismic amblyopia may be initiated from the ganglion cell population of the amblyopic eye. The total clinical picture is confusing because of secondary changes in other parts of the central nervous system. The manifested features can be due to a slower, more enduring type of change (pooling, loss and re-wiring of the neurones) as well as a more transient, adaptive type of response (such as suppression of diplopia). Neurotransmitter replacement has a potential therapeutic application.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Tong LMdoi
10.1016/s0306-9877(97)90275-9subject
Has Abstractpub_date
1997-02-01 00:00:00pages
97-102issue
2eissn
0306-9877issn
1532-2777pii
S0306-9877(97)90275-9journal_volume
48pub_type
杂志文章abstract：:Acute carbon monoxide (CO) poisoning causes the neurologic symptoms and brain lesions during both acute and delayed phase. We propose that catecholamine crises in globus pallidus and deep white matter are the key pathophysiological factors causing acute and delayed brain injuries respectively. Increased sympathetic ac...
journal_title：Medical hypotheses
pub_type： 杂志文章
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journal_title：Medical hypotheses
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journal_title：Medical hypotheses
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2001-02-01 00:00:00
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journal_title：Medical hypotheses
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journal_title：Medical hypotheses
pub_type： 社论
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更新日期：2010-02-01 00:00:00
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更新日期：2015-04-01 00:00:00
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journal_title：Medical hypotheses
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doi：10.1016/j.mehy.2004.03.022
更新日期：2004-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.mehy.2005.06.021
更新日期：2005-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：1981-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：1987-06-01 00:00:00
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journal_title：Medical hypotheses
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更新日期：1997-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：1993-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2010.11.018
更新日期：2011-03-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/s0306-9877(02)00324-9
更新日期：2002-12-01 00:00:00
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doi：10.1016/j.mehy.2013.05.025
更新日期：2013-08-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2019-02-01 00:00:00
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journal_title：Medical hypotheses
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更新日期：2008-12-01 00:00:00
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pub_type： 社论
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journal_title：Medical hypotheses
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更新日期：1988-05-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：1995-11-01 00:00:00
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journal_title：Medical hypotheses
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更新日期：2003-05-01 00:00:00
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journal_title：Medical hypotheses
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doi：10.1016/j.mehy.2017.10.002
更新日期：2017-11-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2011.03.051
更新日期：2011-08-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2009.05.039
更新日期：2010-05-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章,评审
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更新日期：1991-06-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/s0306-9877(02)00296-7
更新日期：2002-12-01 00:00:00
