Interleukin-6 (IL-6) and low O(2) concentration (1%) synergize to improve the maintenance of hematopoietic stem cells (pre-CFC).

abstract：:We have analyzed the regulation of transcription of integrated SV40 DNA and of five cellular genes during the cell cycle of two lines of SV40 transformed mouse 3T3 cells. These cells (ts SV3T3) are temperature sensitive for the expression of the transformed phenotype and at the nonpermissive temperature (39 degrees C)...

journal_title：Journal of cellular physiology

authors： La Bella F,Brown EH,Basilico C

更新日期：1983-10-01 00:00:00

abstract：:Liver regeneration involves not only hepatocyte replication but progenitor aggregation and scarring. Partial hepatectomy (PH), an established model for liver regeneration, reactivates transforming growth factor-β (TGF-β) signaling. Hepatic stellate cells (HSCs) are primarily responding cells for TGF-β and resident in ...

journal_title：Journal of cellular physiology

authors： Chen Z,Wan L,Jin X,Wang W,Li D

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Despite at the beginning known as a benign disease, endometriosis is defined as a risk factor for developing ovarian carcinoma. The effect of endometriosis on ovarian malignancy is known but its role in granulosa cell tumor is still unclear. METHODS AND MATERIALS:In this study, serum samples were collected ...

journal_title：Journal of cellular physiology

authors： Asghari S,Valizadeh Dizajeykan A,Ahmadi M,Barzegari A,Rikhtegar R,Dolati S,Danaii S,Abdollahi-Fard S,Nouri M,Mahdipour M,Yousefi M

更新日期：2019-07-01 00:00:00

abstract：:Obesity, a rising public health burden, is a multifactorial disease with an increased risk for patients to develop several pathological conditions including type 2 diabetes mellitus, hypertension, and cardiovascular disease. Increasing evidence suggests a relationship between the human brain-derived neurotrophic facto...

journal_title：Journal of cellular physiology

authors： Ieraci A,Barbieri SS,Macchi C,Amadio P,Sandrini L,Magni P,Popoli M,Ruscica M

更新日期：2020-12-01 00:00:00

abstract：:rac-1-O-Myristoyl-2-O-acetylglycerol, rac-1-O-palmitoyl-2-O-acetylglycerol, and rac-1-O-oleoyl-2-O-acetylglycerol acted like phorbol myristate acetate and mezerein in stimulating human neutrophil aggregation. Responses to these agents were equally influenced by cytochalasin B, extracellular calcium and magnesium, arac...

journal_title：Journal of cellular physiology

authors： O'Flaherty JT,Schmitt JD,Wykle RL,Redman JF Jr,McCall CE

更新日期：1985-11-01 00:00:00

abstract：:Development and improvement of in vitro culture system supporting self-renewal and unlimited proliferation of porcine pluripotent stem cells (pPSCs) is an indispensable process for the naïve pPSCs establishment. In this study, we modified the previous culture system and attempted to develop a novel chemically defined ...

journal_title：Journal of cellular physiology

authors： Zhang X,Xue B,Li Y,Wei R,Yu Z,Jin J,Zhang Y,Liu Z

更新日期：2019-01-30 00:00:00

abstract：:Lactoferrin, a single chain cationic glycoprotein, present in the secondary granules of neutrophils, acts as a negative feedback regulator of myelopoiesis. Specific receptors for lactoferrin were detected on the surface of different hematopoietic cell types. The influence of lactoferrin on cell growth in culture has b...

journal_title：Journal of cellular physiology

authors： Garré C,Bianchi-Scarrá G,Sirito M,Musso M,Ravazzolo R

更新日期：1992-12-01 00:00:00

abstract：:Sleep-disordered breathing with recurrent apnea (periodic cessation of breathing) results in chronic intermittent hypoxia (IH), which leads to cardiovascular and respiratory pathology. Molecular mechanisms underlying IH-evoked cardio-respiratory co-morbidities have not been delineated. Mice with heterozygous deficienc...

journal_title：Journal of cellular physiology

authors： Yuan G,Nanduri J,Khan S,Semenza GL,Prabhakar NR

更新日期：2008-12-01 00:00:00

abstract：:Galpha(i)-coupled receptors comprise a diverse family of receptors that induce transformation by largely unknown mechanisms. We previously found that the Galpha(i)-coupled dopamine-D2short (D2S) receptor transforms Balb-D2S cells via Gαi3. To identify new Gαi effectors, a yeast two-hybrid screen was done using constit...

journal_title：Journal of cellular physiology

authors： Laliberté B,Wilson AM,Nafisi H,Mao H,Zhou YY,Daigle M,Albert PR

更新日期：2010-11-01 00:00:00

abstract：:During wound healing, myofibroblasts play a central role in matrix formation and wound contraction. At the end of healing, there is evidence that myofibroblasts disappear via apoptotic pathways. Hypertrophic scars are a fibroproliferative disorder that leads to considerable morbidity. It has been postulated that a def...

journal_title：Journal of cellular physiology

authors： Moulin V,Larochelle S,Langlois C,Thibault I,Lopez-Vallé CA,Roy M

更新日期：2004-03-01 00:00:00

abstract：:Several proteases and their specific inhibitors modulate the interdependent processes of cell migration and matrix proteolysis as part of the global program of trauma repair. Expression of plasminogen activator inhibitor type-1 (PAI-1), a serine protease inhibitor (SERPIN) important in the control of barrier proteolys...

journal_title：Journal of cellular physiology

authors： Providence KM,Higgins PJ

更新日期：2004-08-01 00:00:00

abstract：:The main aim of this investigation was to determine whether a functional relationship existed between epidermal growth factor (EGF) and voltage-gated sodium channel (VGSC) upregulation, both associated with strongly metastatic prostate cancer cells. Incubation with EGF for 24 h more than doubled VGSC current density. ...

journal_title：Journal of cellular physiology

authors： Ding Y,Brackenbury WJ,Onganer PU,Montano X,Porter LM,Bates LF,Djamgoz MB

更新日期：2008-04-01 00:00:00

abstract：:Epithelial cells of the airways can, under pathological conditions, undergo squamous metaplasia. The accumulation of cholesterol sulfate has recently been described as a new marker for squamous cell differentiation in rabbit tracheal epithelial cells. We now report that normal human bronchial epithelial cells in cultu...

journal_title：Journal of cellular physiology

authors： Rearick JI,Hesterberg TW,Jetten AM

更新日期：1987-12-01 00:00:00

abstract：:The basic fibroblast growth factor (FGF) is a potent mitogen that has vascular endothelium as one of its principle target cells. Recent work has provided both the complete amino acid sequence of basic FGF and the nucleotide sequence of the genes for both human and bovine basic FGF. Although capillary endothelial cells...

journal_title：Journal of cellular physiology

authors： Hanneken A,Lutty GA,McLeod DS,Robey F,Harvey AK,Hjelmeland LM

更新日期：1989-01-01 00:00:00

abstract：:Keratin intermediate filaments play an important role in maintaining the integrity of the skin structure. Understanding the importance of this subject is possible with the investigation of keratin defects in epidermolysis bullosa simplex (EBS). Nowadays, in addition to clinical criteria, new molecular diagnostic metho...

journal_title：Journal of cellular physiology

authors： Khani P,Ghazi F,Zekri A,Nasri F,Behrangi E,Aghdam AM,Mirzaei H

更新日期：2018-01-01 00:00:00

abstract：:Testicular cancer is the most common solid malignancy among young men. We downloaded data of testicular cancer patients from The Cancer Genome Atlas database to find novel genes in the testicular cancer microenviroment based on ESTIMATE algorithm-derived immune scores. A total of 156 cases of testicular cancer were in...

journal_title：Journal of cellular physiology

authors： Ke ZB,Wu YP,Huang P,Hou J,Chen YH,Dong RN,Lin F,Wei Y,Xue XY,Ng CF,Xu N

更新日期：2021-01-01 00:00:00

abstract：:Increasing evidence supports the idea that the finite proliferative life span of normal fibroblasts is a differentiation-like phenomenon. If this were correct, an ordered sequence of differential gene expression should be associated with the in vitro progression of cells from low passage to high passage (senescence). ...

journal_title：Journal of cellular physiology

authors： Choi AM,Olsen DR,Cook KG,Deamond SF,Uitto J,Bruce SA

更新日期：1992-04-01 00:00:00

abstract：:Pulmonary fibrosis is a potentially fatal consequence of treatments for malignancy and is an increasing problem in bone marrow transplant patients and in cases of allogenic lung transplant. The fibrotic response is characterized by increases in lung fibroblast number and collagen synthesis. This laboratory previously ...

journal_title：Journal of cellular physiology

authors： Sempowski GD,Derdak S,Phipps RP

更新日期：1996-05-01 00:00:00

abstract：:Temperature-sensitive mutants have revealed a region of the herpes simplex virus 1 genome that affects both the uptake of hexose and the synthesis of heat shock proteins. Other inducers of heat-shock proteins, namely heat shock itself and arsenite, likewise induce an increased uptake of hexose. The increased uptake, l...

journal_title：Journal of cellular physiology

authors： Warren AP,James MH,Menzies DE,Widnell CC,Whitaker-Dowling PA,Pasternak CA

更新日期：1986-09-01 00:00:00

abstract：:These studies describe a liquid suspension culture system for normal myeloid cells derived from human foetal liver. A simple one-step fractionation procedure was employed to obtain a cell population capable of expanding into all stages of myeloid differentiation, including committed myeloid progenitor cells (GM-CFC). ...

journal_title：Journal of cellular physiology

authors： Toksoz D,Brown G

更新日期：1984-05-01 00:00:00

abstract：:We determined the mitogenic and comitogenic properties of tumor promoters in the indole alkaloid series; agents that differ structurally from 12-0-tetradecanoylphorbol-13-acetate (TPA), which is known to be a lymphocyte mitogen. Teleocidin and dihydroteleocidin B were mitogenic for human lymphocytes, and lyngbyatoxin ...

journal_title：Journal of cellular physiology

authors： Novogrodsky A,Patya M,Fujiki H,Rubin AL,Stenzel KH

更新日期：1984-07-01 00:00:00

abstract：:Minute virus of mice (MVM), a non-defective parvovirus, has been shown to infect cultures of non-pluripotent differentiated teratocarcinoma-derived cells, but pluripotent (and "nullipotent") embryonal carcinoma cells derived from the same teratocarcinoma resist MVN infection. Somatic cell hybrids between an embryonal ...

journal_title：Journal of cellular physiology

authors： Miller RA,Ward DC,Ruddle FH

更新日期：1977-06-01 00:00:00

abstract：:Tumor ischemia participates in angiogenesis and cancer progression through cellular responses to hypoxia and nutrient deprivation. However, the contribution of amino acids limitation to this process remains poorly understood. Using serum-free cell culture conditions, we tested the impact of L-glutamine deprivation on ...

journal_title：Journal of cellular physiology

authors： Drogat B,Bouchecareilh M,North S,Petibois C,Déléris G,Chevet E,Bikfalvi A,Moenner M

更新日期：2007-08-01 00:00:00

abstract：:Fetal brown adipocytes expressed uncoupling protein 1 (UCP1) mRNA, this expression being blunted throughout culture for 24 h in a serum-free medium. At physiological doses, either insulin-like growth factor I (IGF-I) or insulin turned out to be as potent as dibutyryl cAMP (dbcAMP) in increasing UCP1 gene transcription...

journal_title：Journal of cellular physiology

authors： Teruel T,Valverde AM,Navarro P,Benito M,Lorenzo M

更新日期：1998-07-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) is one of the critical infectious agents with thousands of newly infected people worldwide. High mutational capability and rapid diversification, inhibition of humoral and cellular immune responses, and thus inability for recognition of an immunogenic region in the viral envelope by ...

journal_title：Journal of cellular physiology

authors： Mazarzaei A,Vafaei M,Ghasemian A,Mirforughi SA,Rajabi Vardanjani H,Alwan NAS

更新日期：2019-02-18 00:00:00

abstract：:Eukaryotic translation initiation factor 5A (eIF5A) has a unique character: the presence of an unusual amino acid, hypusine, which is formed by post-translational modifications. Even before the identification of hypusination in eIF5A, the correlation between hypusine formation and protein synthesis, shifting cell prol...

journal_title：Journal of cellular physiology

authors： Parreiras-e-Silva LT,Luchessi AD,Reis RI,Oliver C,Jamur MC,Ramos RG,Oliveira EB,Curi R,Costa-Neto CM

更新日期：2010-11-01 00:00:00

abstract：:The components of the insulin-like growth factor (IGF) axis and their roles in regulating proliferation and differentiation of the human colon adenocarcinoma cell line, Caco-2, have been investigated. Caco-2 cells proliferated in serum-free medium at 75% the rate observed in medium containing 10% fetal bovine serum. I...

journal_title：Journal of cellular physiology

authors： Park JH,Corkins MR,Vanderhoof JA,Caruso NM,Hrbek MJ,Schaffer BS,Slentz DH,McCusker RH,MacDonald RG

更新日期：1996-02-01 00:00:00

abstract：:Heparin and related glycosaminoglycans are potent inhibitors of both in vivo and in vitro smooth muscle cell (SMC) proliferation. We have found that epidermal growth factor (EGF) reverses the antiproliferative effects of heparin. Other known SMC mitogens, including platelet-derived growth factor (PDGF), insulin-like g...

journal_title：Journal of cellular physiology

authors： Reilly CF,Fritze LM,Rosenberg RD

更新日期：1987-05-01 00:00:00

abstract：:Adhesion of human monocytes and granulocytes to vascular endothelium plays an important role in migration of these cells to inflammatory sites in tissues. A family of three human leukocyte heterodimeric surface molecules named Mo1, LFA-1, and p150,95 (LeuM5) has been shown to mediate leukocyte adhesion to confluent mo...

journal_title：Journal of cellular physiology

authors： Arnaout MA,Lanier LL,Faller DV

更新日期：1988-11-01 00:00:00

abstract：:A proliferation inducing ligand (APRIL or TALL-2 and TRDL-1) was first discovered as a cytokine over-expressed in many transformed cells and with the capacity to stimulate proliferation. APRIL was shown to bind two different receptors of the TNF receptor superfamily: B cell maturation antigen (BCMA) and transmembrane ...

journal_title：Journal of cellular physiology

authors： Kimberley FC,Hahne M,Medema JP

更新日期：2009-01-01 00:00:00