Identification of novel genes in testicular cancer microenvironment based on ESTIMATE algorithm-derived immune scores.

abstract：:To determine if Chinese Hamster Ovary (CHO) cells in culture are able to metabolize steroids, CHO cells were incubated in defined medium with [14C]pregnenolone. As shown, [14C]pregnenolone is metabolized to progesterone and other delta 53 beta steroids; this steroidogenic response is appreciably enhanced upon exposure...

journal_title：Journal of cellular physiology

authors： Evain D,Anderson WB,Saez MJ

更新日期：1981-07-01 00:00:00

abstract：:Vascular endothelial cells receive proangiogenic or antiangiogenic signals from components of extracellular matrix (ECM) depending upon the situation and many molecular signals can have opposite effects in different vascular beds. Tissue inhibitor of metalloproteinase 1 is antiangiogenic in several tissues, but promot...

journal_title：Journal of cellular physiology

authors： Lima E Silva R,Kachi S,Akiyama H,Shen J,Aslam S,Yuan Gong Y,Khu NH,Hatara MC,Boutaud A,Peterson R,Campochiaro PA

更新日期：2006-07-01 00:00:00

abstract：:Mast cells are central regulators of allergic inflammation through production of various chemical mediators and cytokines. Bacterial infection occasionally worsens allergic inflammation. Although the exact mechanism of this phenomenon remains unclear, we have previously reported that LPS stimulates mast cells to produ...

journal_title：Journal of cellular physiology

authors： Chiba N,Masuda A,Yoshikai Y,Matsuguchi T

更新日期：2007-10-01 00:00:00

abstract：:An efficient regulation of fuel metabolism in response to internal and environmental stimuli is a vital task that requires an intact carnitine system. The carnitine system, comprehensive of carnitine, its derivatives, and proteins involved in its transformation and transport, is indispensable for glucose and lipid met...

journal_title：Journal of cellular physiology

authors： Peluso G,Nicolai R,Reda E,Benatti P,Barbarisi A,Calvani M

更新日期：2000-03-01 00:00:00

abstract：:We examined the effects of thrombin on thromboxane generation by sheep neutrophils and lymphocytes in vitro. Physiological concentration of thrombin (50 nM) resulted in thromboxane B2 generation from both neutrophils and lymphocytes, which was comparable to that obtained with zymosan activated serum challenge of the c...

journal_title：Journal of cellular physiology

authors： Bizios R,Lai L,Fenton JW 2nd,Malik AB

更新日期：1987-08-01 00:00:00

abstract：:The polyphenolic compounds curcumin and quercetin increased sensitivity of ovarian cancer cells (CAOV3 and SKOV3) to cisplatin. The effect was obtained when the compounds were added simultaneously with cisplatin, as well as when they were added 24 h before. High serum levels of certain cytokines, for example interleuk...

journal_title：Journal of cellular physiology

authors： Chan MM,Fong D,Soprano KJ,Holmes WF,Heverling H

更新日期：2003-01-01 00:00:00

abstract：:Retinoic acid inhibits proliferation of hormone-dependent, but not hormone-independent breast cancer cells. Retinoic acid-induced changes in cellular proliferation and differentiation are associated with disturbances in growth factor signaling and frequently with changes in protein kinase C expression. PKC delta, epsi...

journal_title：Journal of cellular physiology

authors： Cho Y,Tighe AP,Talmage DA

更新日期：1997-09-01 00:00:00

abstract：:Low-grade chronic inflammation is a salient feature of obesity and many associated disorders. This condition frequently occurs in central obesity and is connected to alterations of the visceral adipose tissue (AT) microenvironment. Understanding how obesity is related to inflammation may allow the development of thera...

journal_title：Journal of cellular physiology

authors： Petrangeli E,Coroniti G,Brini AT,de Girolamo L,Stanco D,Niada S,Silecchia G,Morgante E,Lubrano C,Russo MA,Salvatori L

更新日期：2016-03-01 00:00:00

abstract：:Cancer cell lines have contributed immensely in understanding the complex physiology of cancers. They are excellent material for studies as they offer homogenous samples without individual variations and can be utilised with ease and flexibility. Also, the number of assays and end-points one can study is almost limitl...

journal_title：Journal of cellular physiology

authors： Ravi M,Ramesh A,Pattabhi A

更新日期：2017-10-01 00:00:00

abstract：:Nucleotide receptors signaling affects cell proliferation, with possible implications on tumorigenic processes. However, molecular targets and action mechanisms of the extracellular nucleotides are still poorly elucidated. We have previously shown in ARO cells that APE1/Ref-1, a transcriptional coactivator responsible...

journal_title：Journal of cellular physiology

authors： Pines A,Bivi N,Vascotto C,Romanello M,D'Ambrosio C,Scaloni A,Damante G,Morisi R,Filetti S,Ferretti E,Quadrifoglio F,Tell G

更新日期：2006-10-01 00:00:00

abstract：:Hedgehog (Hh) family members are involved in multiple cellular processes including proliferation, migration, differentiation, and cell fate determination. Recently, the novel Hh agonists Hh-Ag 1.3 and 1.7 were identified in a high-throughput screening of small molecule compounds that activate the expression of Gli1, a...

journal_title：Journal of cellular physiology

authors： Nakamura T,Naruse M,Chiba Y,Komori T,Sasaki K,Iwamoto M,Fukumoto S

更新日期：2015-04-01 00:00:00

abstract：:Apoptosis is involved in both the cellular and humoral immune system destroying tumors. An apoptosis-inducing factor from HL-60 myeloid leukemia cells was obtained, purified, and sequenced. The protein found has been identified as a human complement factor B-derived fragment Bb, although it is known that factor B is a...

journal_title：Journal of cellular physiology

authors： Uwai M,Terui Y,Mishima Y,Tomizuka H,Ikeda M,Itoh T,Mori M,Ueda M,Inoue R,Yamada M,Hayasawa H,Horiuchi T,Niho Y,Matsumoto M,Ishizaka Y,Ikeda K,Ozawa K,Hatake K

更新日期：2000-11-01 00:00:00

abstract：:The growth response of cultured rat intestinal epithelial (RIE-1) cells to epidermal growth factor (EGF) depends on the cell population density. EGF stimulated the proliferation of RIE-1 cells in dense cultures, but inhibited the proliferation of cells growing at low population densities. In contrast, insulin enhanced...

journal_title：Journal of cellular physiology

authors： Blay J,Brown KD

更新日期：1986-12-01 00:00:00

abstract：:Mesenchymal stromal cells (MSCs) have been widely exploited for the treatment of several conditions due to their intrinsic regenerative and immunomodulatory properties. MSC have demonstrated to be particularly relevant for the treatment of ischemic diseases, where MSC-based therapies can stimulate angiogenesis and ind...

journal_title：Journal of cellular physiology

authors： Pinto DS,Ahsan T,Serra J,Fernandes-Platzgummer A,Cabral JMS,da Silva CL

更新日期：2020-10-01 00:00:00

abstract：:Protein-DNA interactions within the promoter of a cell cycle-regulated human H4 histone gene were examined by binding of 5'-end-labeled DNA segments to Western blots of nuclear protein fractions. Specific protein interactions were observed with DNA segments located between -500 bp and -1,070 bp upstream of the ATG ini...

journal_title：Journal of cellular physiology

authors： Pauli U,Chiu JF,Ditullio P,Kroeger P,Shalhoub V,Rowe T,Stein G,Stein J

更新日期：1989-05-01 00:00:00

abstract：:The influence upon different cellular and humoral parameters of hemopoiesis of three structurally unrelated, highly purified bacterial cell-wall components (BCWC) was investigated. The spleens of C57BL/6 mice assayed 6 days after the injection of either lipid A or outer-membrane lipoportein, but not murein, showed a m...

journal_title：Journal of cellular physiology

authors： Staber FG,Johnson GR

更新日期：1980-10-01 00:00:00

abstract：:The prevalence of chronic hyperglycemia and its complications, imposing a critical burden on the worldwide economy and the global healthcare system, is a pressing issue. Mounting evidence indicates that oxidative stress and hypoxia, two noticeable features of hyperglycemia, play a joint crucial role in mediating cellu...

journal_title：Journal of cellular physiology

authors： Huang YT,Liu CH,Yang YC,Aneja R,Wen SY,Huang CY,Kuo WW

更新日期：2019-08-01 00:00:00

abstract：:Proteolytic cleavage of extracellular matrix (ECM) and disruption of tissue architecture are fundamental features of tumor cell invasion. The proteolytic activity is focused in close proximity to the tumor cells. Here, we describe the possibility to quantify local proteolytic activity in the microenvironment of larger...

journal_title：Journal of cellular physiology

authors： Ludwig T,Püttmann S,Bertram H,Tatenhorst L,Paulus W,Oberleithner H,Senner V

更新日期：2005-03-01 00:00:00

abstract：:The extracellular matrix (ECM) is a dynamic component of tissue architecture that physically supports cells and actively influences their behavior. In the context of bone regeneration, cell-secreted ECMs have become of interest as they reproduce tissue-architecture and modulate the promising properties of mesenchymal ...

journal_title：Journal of cellular physiology

authors： Baroncelli M,van der Eerden BC,Kan YY,Alves RD,Demmers JA,van de Peppel J,van Leeuwen JP

更新日期：2018-01-01 00:00:00

abstract：:Immunotherapy has caused a paradigm shift in the treatment of several malignancies, particularly the blockade of programmed death-1 (PD-1) and its specific receptor/ligand PD-L1 that have revolutionized the treatment of a variety of malignancies, but significant durable responses only occur in a small percentage of pa...

journal_title：Journal of cellular physiology

authors： Rahimi Kalateh Shah Mohammad G,Ghahremanloo A,Soltani A,Fathi E,Hashemy SI

更新日期：2020-07-01 00:00:00

abstract：:Optical tweezers were used to scan individual Chronic Myelogenous Leukemia cells to determine if the cell death depends on the scanning conditions. Although increasing the scanning frequency or amplitude means greater force applied to the cells, their effects on cell death are not a simple increasing trend, as observe...

journal_title：Journal of cellular physiology

authors： Ng KS,Zhou ZL,Ngan AH

更新日期：2013-10-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS), characterized by acute hypoxic respiratory dysfunction or failure, is a manifestation of multiple organ failure in the lung, and the most common risk factor is sepsis. We previously showed that blocking α2 -adrenoceptor (α2 -AR) could attenuate lung injury induced by endotox...

journal_title：Journal of cellular physiology

authors： Cong Z,Li D,Tao Y,Lv X,Zhu X

更新日期：2020-10-01 00:00:00

abstract：:While mesenchymal stem cells (MSCs) have been widely used to repair radiation-induced bone damage, the molecular mechanism underlying the effects of MSCs in the maintenance of bone homeostasis under radiation stress remains largely unknown. In this study, the role and mechanisms of R-spondin 1 (Rspo1)-leucine-rich rep...

journal_title：Journal of cellular physiology

authors： Chen X,Chen L,Tan J,Zhang L,Xia J,Cheng B,Zhang W

更新日期：2021-01-16 00:00:00

abstract：:Optical indicators of the cationic, cyanine and anionic oxonol classes were used to evaluate the plasma membrane potential of animal cells in suspension and in monolayer culture. The optical signals were calibrated by using diffusion potentials either of K+ (in the presence of valinomycin) or of H+ (in the presence of...

journal_title：Journal of cellular physiology

authors： Bashford CL,Alder GM,Gray MA,Micklem KJ,Taylor CC,Turek PJ,Pasternak CA

更新日期：1985-06-01 00:00:00

abstract：:Epigallocatechin-3-gallate (EGCG) plays a crucial role in hepatic lipid metabolism. However, the underlying regulatory mechanism of hepatic lipid metabolism by EGCG in canine is unclear. Primary canine hepatocytes were treated with EGCG (0.01, 0.1, or 1 μM) and BML-275 (an AMP-activated protein kinase [AMPK] inhibitor...

journal_title：Journal of cellular physiology

authors： Ding H,Li Y,Li W,Tao H,Liu L,Zhang C,Kong T,Feng S,Li J,Wang X,Wu J

更新日期：2021-01-01 00:00:00

abstract：:Characteristic features like self-renewal, multilineage differentiation potential, and immune-modulatory/anti-inflammatory properties, besides the ability to mobilize and home distant tissues make stem cells (SCs) a lifeline for an individual. Stem cells (SCs) if could be harvested and expanded without any abnormal ch...

journal_title：Journal of cellular physiology

authors： Gugjoo MB,Amarpal,Fazili MR,Shah RA,Sharma GT

更新日期：2019-06-01 00:00:00

abstract：:Various types of anesthesia are being utilized to maintain physiologically secured surgical conditions. Nearly all categories of general anesthesia are characterized by various perioperative and postoperative complications. These shortcomings are important aspects that need to be considered by the anesthesiologist and...

journal_title：Journal of cellular physiology

authors： Alizadeh R,Fard ZA

更新日期：2019-08-01 00:00:00

abstract：:The profiles of actions of lipoxin A4 (LXA4) and lipoxin B4 (LXB4), two lipoxygenase-derived eicosanoids, were examined with human neutrophils. At nanomolar concentrations, LXA4 and LXB4 each stimulated the release of [1-14C]arachidonic acid from esterified sources in neutrophils. Lipoxin-induced release of [1-14C]ara...

journal_title：Journal of cellular physiology

authors： Nigam S,Fiore S,Luscinskas FW,Serhan CN

更新日期：1990-06-01 00:00:00

abstract：:We describe the isolation and characterization of a Chinese hamster ovary cell line selected for resistance to N-carbamoyloxyurea. Using the mammalian cell permeabilization assay developed in our laboratory, a detailed analysis of the target enzyme, ribonucleotide reductase (EC 1.17.4.1), was carried out. Both drug-re...

journal_title：Journal of cellular physiology

authors： Hards RG,Wright JA

更新日期：1981-02-01 00:00:00

abstract：:Fluorescence anisotropy measurements are widely used as sensitive indicators of cell membrane fluidity. 1-[4-(trimethylamino)phenyl]-6-phenyl hexa-1,3,5-triene (TMA-DPH) is a cationic fluorescent aromatic hydrocarbon that anchors at the lipid-water interface of membrane lipid bilayers. Its uptake into porcine pulmonar...

journal_title：Journal of cellular physiology

authors： Sheridan NP,Block ER

更新日期：1988-01-01 00:00:00