Abstract：
:The possibility that fitness relationships associated with an inversion polymorphism in D. paulistorum were frequency dependent was investigated. Using allozymes of tetrazolium oxidase to mark inversions, the effects of genotype frequency, larval density, and culture conditions on fitness were assessed. The proportions of genotypes among egg-laying females were varied, thus changing the expected proportions of progeny produced in the absence of fecundity or viability selection. The genotypes of progeny were determined by electrophoresis and comparisons of the ratio of the numbers of the different genotypes produced to the expected ratio was used to evaluate fitness relationships. Fitness relationships were dependent on genotype frequency, larval density, and culture conditions. Selection was either absent, directional, frequency dependent (favoring rare types), or heterotic depending on density and culture conditions. It is implied that the adaptive value of genetic variants need not be apparent in all environments, or may change with changing conditions. There is evidence for different criteria for selection in the two sexes. These results add to the evidence supporting the importance of frequency-dependent selection. It is argued that for frequency dependence to be of general importance, selection must act on genes in groups, either as an inversion or as lengths of chromosome with integrity maintained by disequilibrium.
journal_name
Geneticsjournal_title
Geneticsauthors
Gromko MH,Richmond RCsubject
Has Abstractpub_date
1978-02-01 00:00:00pages
357-66issue
2eissn
0016-6731issn
1943-2631journal_volume
88pub_type
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