Genetically engineered mice in understanding the basis of neonatal lung disease.

abstract：:Neonatal hyperbilirubinemia is a normal postnatal phenomenon resulting from a transitional imbalance between the production and elimination of bilirubin in the neonate. Bilirubin has been shown to be not only a potent antioxidant, but also toxic at excessive concentrations. As a result, the biology of bilirubin, its p...

journal_title：Seminars in perinatology

authors： Stevenson DK,Vreman HJ,Wong RJ,Contag CH

更新日期：2001-04-01 00:00:00

abstract：:Medical and psychological indications for lactation suppression are discussed, and methods for lactation suppression are evaluated. Medical indications for lactation suppression include 1) maternal anatomical abnormalities, such as inadequate secretory tissue and inverted nipples; 2) maternal breast infections and tu...

journal_title：Seminars in perinatology

authors： Harrison RG

更新日期：1979-07-01 00:00:00

abstract：:Twin birth rates have increased dramatically over the past three decades, and twins currently account for 3% of all pregnancies. Twin pregnancies of any type are at risk for prematurity. In addition, monochorionic twin pregnancies (25-30% of all twin pregnancies) are predisposed to a specific set of complications, inc...

journal_title：Seminars in perinatology

authors： Paepe ME

更新日期：2015-02-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs are frequently used during pregnancy (premature labor, polyhydramnios) and the immediate postnatal period (closure of patent ductus arteriosus). This article evaluates the renal effect of 3 nonspecific COX inhibitors (aspirin, indomethacin, and ibuprofen) in newborn rabbits. Five g...

journal_title：Seminars in perinatology

authors： Guignard JP

更新日期：2002-12-01 00:00:00

abstract：:Fetal and neonatal alloimmune thrombocytopenia is not a well-known disease, except among specialists in maternal-fetal medicine, neonatologists, and certain pediatricians (ie, hematologists). However, this is by far the most common cause of early severe thrombocytopenia in neonates and of intracranial hemorrhage in te...

journal_title：Seminars in perinatology

authors： Bussel JB,Sola-Visner M

更新日期：2009-02-01 00:00:00

abstract：:The rapid rise of novel coronavirus disease 2019 (COVID-19) cases led the American Society for Reproductive Medicine (ASRM) to recommend immediate cessation of all new fertility treatment cycles on March 17, 2020. Controversial from the start, providers and patients expressed their opposition through online petitions,...

journal_title：Seminars in perinatology

authors： Gemmell LC,Williams Z,Forman EJ

更新日期：2020-11-01 00:00:00

abstract：:Thyroid hormone plays an important role in regulating cardiovascular function during the transition to extrauterine physiology. Multiple mechanisms participate, ranging from transcriptional to more immediate nongenomic modes of regulation. ...

journal_title：Seminars in perinatology

authors： Portman MA

更新日期：2008-12-01 00:00:00

abstract：:Obstetric hemorrhage is often a sudden, life-threatening event. Successful management hinges on both preoperative preparation if hemorrhage is anticipated as well as knowledge of interventions. Uterine-sparing techniques, such as aggressive and early use of uterotonics, balloon tamponade, uterine compression sutures, ...

journal_title：Seminars in perinatology

authors： Shah M,Wright JD

更新日期：2009-04-01 00:00:00

abstract：:Determining approach to delivery after a previous cesarean is among the most contentious areas of obstetrics. We present a framework for ethically responsible guidelines and practice regarding vaginal birth after cesarean. We describe ethical complexities of 3 key issues that mark the debate: the cesarean delivery rat...

journal_title：Seminars in perinatology

authors： Lyerly AD,Little MO

更新日期：2010-10-01 00:00:00

abstract：:Concern over the influence of pregnancy-related alterations in hydration has prompted questions regarding the accuracy of using standard methods of determining body composition. We sought to investigate whether differences exist between body composition determined at 30 weeks and 39 weeks of gestation and postpartum, ...

journal_title：Seminars in perinatology

authors： Jaque-Fortunato SV,Khodiguian N,Artal R,Wiswell RA

更新日期：1996-08-01 00:00:00

abstract：:The genetic sonogram is a composite algorithm combining multiple individual markers to increase Down syndrome risk prediction. Transformation of sonographic information into a standard mathematical format represented an early challenge that has now been surmounted. Using increasingly sophisticated mathematical techniq...

journal_title：Seminars in perinatology

authors： Bahado-Singh RO,Oz UA,Mendilcioglu I,Mahoney MJ

更新日期：2005-08-01 00:00:00

abstract：:Poorly controlled maternal diabetes in pregnancy may delay fetal pulmonary maturation. However, diabetic women with good glycemic control have fetal lung maturation at the same gestational age as nondiabetic women. With modern ultrasound technology, gestational dates can be accurately assessed in the first or early se...

journal_title：Seminars in perinatology

authors： Piper JM

更新日期：2002-06-01 00:00:00

abstract：:The American Heart Association (AHA) categorizes pulmonary embolism (PE) into three main categories based on the presence or absence of hemodynamic changes and evidence of right ventricular dysfunction. The AHA characterizes massive PE as occurring in the setting of persistent hypotension, profound bradycardia, or pul...

journal_title：Seminars in perinatology

authors： Handal-Orefice RC,Moroz LA

更新日期：2019-06-01 00:00:00

abstract：:A large body of research indicates that children born very preterm are at increased risk for neurobehavioral impairments; however, research examining outcome for extremely preterm (EP) children is limited. This chapter will review the literature focusing on early development delay, general intellectual functioning, sp...

journal_title：Seminars in perinatology

authors： Anderson PJ,Doyle LW

更新日期：2008-02-01 00:00:00

abstract：:Late preterm infants (34-37 weeks postmenstrual age at birth) are intermediate between less mature preterm infants and infants born at 38 weeks or more in regard to autonomic brain stem maturation. Ventilatory responses to CO(2) in preterm infants born at 33 to 36 week are significantly higher than in infants born at ...

journal_title：Seminars in perinatology

authors： Hunt CE

更新日期：2006-04-01 00:00:00

abstract：:Cesarean birth (CB) rates are rising, globally. The global burden of CB is having a mixed effect on pregnancy outcomes and requires significant clinical and economic resources. The context of CB care in low- and middle-income countries is further complicated by barriers to facility-based care itself, followed by issue...

journal_title：Seminars in perinatology

authors： Harrison MS,Goldenberg RL

更新日期：2019-08-01 00:00:00

abstract：:The neurodevelopmental outcome of very low birth weight infants experiencing early-onset intraventricular hemorrhage (IVH) occurring within the first 6 postnatal hours was compared with that of their peers without early-onset IVH at 3 years corrected age. The 440 surviving preterm infants (birth weight 600 to 1,250 g)...

journal_title：Seminars in perinatology

authors： Vohr B,Allan WC,Scott DT,Katz KH,Schneider KC,Makuch RW,Ment LR

更新日期：1999-06-01 00:00:00

abstract：:Poor access to contraception can lead to several undesired health outcomes, including high rates of unintended pregnancy, high rates of teen pregnancy, spontaneous preterm delivery, preeclampsia and maternal death. Properly addressing these public health issues often require a coordinated response at the state governm...

journal_title：Seminars in perinatology

authors： Jackson AD,Sherpa ML

更新日期：2020-08-01 00:00:00

abstract：:Until recent years, prenatal genetic tests have been almost exclusively developed and implemented by academic physicians and laboratories. In the last several years, industry has led the development of novel prenatal genetic tests, funded clinical trials and implemented these tests into clinical practice. That these e...

journal_title：Seminars in perinatology

authors： Swanson A,Goldberg JD

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To describe inpatient management strategies and considerations for pregnant patients with severe acute respiratory syndrome coronavirus 2 infection. FINDINGS:The novel coronavirus has posed challenges to both obstetric patients and the staff caring for them, due to its variable presentation and current limit...

journal_title：Seminars in perinatology

authors： Aubey J,Zork N,Sheen JJ

更新日期：2020-11-01 00:00:00

abstract：:Preterm birth occurs in 7% to 12% of all deliveries, but accounts for over 85% of all perinatal morbidity and mortality. Although the ability of obstetric care providers to identify women at risk for preterm delivery has improved, the overall incidence of preterm birth has remained unchanged for the past 30 years. Pre...

journal_title：Seminars in perinatology

authors： Norwitz ER,Robinson JN

更新日期：2001-08-01 00:00:00

abstract：:Surviving extremely low-birth-weight infants are at risk of severe neurodevelopmental disability. Transfusion with packed red cells is almost universal in the care of these infants, but the hemoglobin threshold at which these transfusions should be given is unclear. Different clinical trials of restrictive (low hemogl...

journal_title：Seminars in perinatology

authors： Whyte RK

更新日期：2012-08-01 00:00:00

abstract：:Acute renal failure in the newborn is a common problem and is typically classified as prerenal, intrinsic renal disease including vascular insults, and obstructive uropathy. In the newborn, renal failure may have a prenatal onset in congenital diseases such as renal dysplasia with or without obstructive uropathy and i...

journal_title：Seminars in perinatology

authors： Andreoli SP

更新日期：2004-04-01 00:00:00

abstract：:Abruptio placentae is an important cause of vaginal bleeding in the latter half of pregnancy. The key factor in the pathophysiology is hemorrhage at the decidual-placental interface. Small episodes may escape clinical detection, but severe grades impact significantly on fetal and maternal morbidity and mortality, with...

journal_title：Seminars in perinatology

authors： Hall DR

更新日期：2009-06-01 00:00:00

abstract：:Before sounds originating outside the abdomen of pregnant women can reach the inner ear of the fetus, they must first pass through the tissues and fluids surrounding the fetal head. Low-frequency sound energy easily penetrates to the fetal head, less than 5 dB attenuation for frequencies below 500 Hz, whereas higher f...

journal_title：Seminars in perinatology

authors： Gerhardt KJ,Abrams RM

更新日期：1996-02-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a leading cause of severe maternal morbidity and mortality. While pregnancy alone is a risk factor for VTE, additional population-based risk factors such as obesity are becoming increasingly common, particularly in the developed world. Maternal death from VTE is amenable to prevention a...

journal_title：Seminars in perinatology

authors： Friedman AM,Ananth CV

更新日期：2016-03-01 00:00:00

abstract：:The intended and unintended effects of epidural labor analgesia are reviewed. Mothers randomized to epidural rather than parenteral opioid analgesia have better pain relief. Fetal oxygenation is not affected by analgesic method; however, neonates whose mothers received intravenous or intramuscular opioids rather than ...

journal_title：Seminars in perinatology

authors： Leighton BL,Halpern SH

更新日期：2002-04-01 00:00:00

abstract：:Cirrhosis and portal hypertension infrequently coincide with pregnancy but increase maternal and fetal morbidity and mortality when present. Chronic liver disease and portal hypertension are not contraindications to pregnancy but necessitate intensive monitoring throughout pregnancy. The complications of liver disease...

journal_title：Seminars in perinatology

authors： Russell MA,Craigo SD

更新日期：1998-04-01 00:00:00

abstract：:Minimally invasive surgery has been one of the most important surgical advances in the last 15 years. The development of smaller instruments has allowed pediatric surgeons to apply this rapidly evolving technology to neonates. Congenital neonatal deformities including tracheoesophageal fistula, patent ductus arteriosu...

journal_title：Seminars in perinatology

authors： Georgeson KE,Robertson DJ

更新日期：2004-06-01 00:00:00

abstract：:Extreme hyperbilirubinemia can cause bilirubin neurotoxicity. Infants with glucose-6-phosphate dehydrogenase (G6PD) deficiency can develop hemolysis and thus are at high risk. We evaluated a device that quantitatively measures G6PD activity kinetically using digital microfluidics (DMF). Intra- and inter-instrument and...

journal_title：Seminars in perinatology

authors： Wong RJ,Montiel C,Kunda M,Stevenson DK,Bhutani VK

更新日期：2021-02-01 00:00:00