Abstract:
:High-density lipoproteins (HDLs) have been well established to protect against the development of atherosclerotic cardiovascular disease. It has become apparent that in addition to the promotion of reverse cholesterol transport, HDLs possess a number of additional functional properties that may contribute to their beneficial influence on the arterial wall. A number of exciting therapeutic strategies have been developed that target HDL and its ability to protect against the development of atherosclerotic plaque. This paper will review how the promotion of the functional properties of HDL inhibits the formation of atherosclerotic plaque and stabilises lesions in patients with established disease.
journal_name
Cell Resjournal_title
Cell researchauthors
Cutri BA,Hime NJ,Nicholls SJdoi
10.1038/sj.cr.7310097subject
Has Abstractpub_date
2006-10-01 00:00:00pages
799-808issue
10eissn
1001-0602issn
1748-7838pii
7310097journal_volume
16pub_type
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