Human serum amyloid P component binds to peripheral blood monocytes.

abstract：:Chronic hepatitis B virus (HBV) infection affects millions of people worldwide and about half a million people die every year. India represents the second largest pool of chronic HBV infections with an estimated 40 million chronically infected patients. Persistence or clearance of HBV infection mainly depends upon hos...

journal_title：Scandinavian journal of immunology

authors： Vyas AK,Jindal A,Hissar S,Ramakrishna G,Trehanpati N

更新日期：2017-07-01 00:00:00

abstract：:We have recently shown that a heat treatment of a murine target cell line, WEHI 164, induces resistance to lysis mediated by tumour necrosis factors alpha (TNF-alpha) and beta (TNF-beta). In the present study the effect of the heat shock of target cells on cytotoxicity mediated by natural killer cells (NK cells), lymp...

journal_title：Scandinavian journal of immunology

authors： Jäättelä M

更新日期：1990-02-01 00:00:00

abstract：:After 3-5 days of in vitro culture, peritoneal cells from untreated C3H mice produce autoantibodies specific for autoantigens in the membranes of mouse erythrocytes. The autoantigens are exposed in vitro by treating mouse erythrocytes with the proteolytic enzyme bromelain. Limiting-dilution cell culture techniques wer...

journal_title：Scandinavian journal of immunology

authors： Cox KO,Daenke S,Samcewicz B

更新日期：1984-12-01 00:00:00

abstract：:The tumour necrosis factor-α (TNF-α) promoter -308 A/G polymorphism plays an important role in the aetiology of systemic lupus erythematosus (SLE). Several studies have estimated the association between TNF-α -308 A/G and SLE risk. However, results were inconsistent. A case-control study was carried out to explore the...

journal_title：Scandinavian journal of immunology

authors： Yang ZC,Xu F,Tang M,Xiong X

更新日期：2017-03-01 00:00:00

abstract：:Cytokines produced by tumour and immune cells may play a significant role in a modulation of immune cells response against tumour. We investigated an ability of peripheral blood mononuclear cells (PBMC) of patients with early and advanced stages of ovarian cancer and from non-cancer patients to produce various cytokin...

journal_title：Scandinavian journal of immunology

authors： Nowak M,Klink M,Glowacka E,Sulowska Z,Kulig A,Szpakowski M,Szyllo K,Tchorzewski H

更新日期：2010-02-01 00:00:00

abstract：:The effect of adjuvant on induction of human papillomavirus type 16 E7 protein-specific cytotoxic T lymphocytes (CTL) and immunoglobulin G (IgG)2a antibody was studied in C57BL/6 J mice immunized with various adjuvants and E7 protein. Quil-A adjuvant, but not complete Freund's adjuvant (CFA) or Algammulin, induced a T...

journal_title：Scandinavian journal of immunology

authors： Fernando GJ,Stewart TJ,Tindle RW,Frazer IH

更新日期：1998-05-01 00:00:00

abstract：:T cells from immune guinea-pigs produce clusters in vitro with macrophages pulsed with soluble protein antigens. The formation of clusters is antigen-specific. Time-lapse cinephotomicrography was used to study the sequence of events leading to cluster formation and the kinetics of already formed clusters. The central ...

journal_title：Scandinavian journal of immunology

authors： Petri J,Braendstrup O,Werdelin O

更新日期：1979-01-01 00:00:00

abstract：:Cytokine-immunoglobulin (Ig)-fusion proteins have attracted increasing interest as antitumour agents. Here, we have investigated the antimetastatic and antitumour responses elicited in vivo by mammary adenocarcinoma cells (TS/A) engineered to secrete interleukin (IL)-2-IgG fusion proteins. TS/A cells were transfected ...

journal_title：Scandinavian journal of immunology

authors： Budagian V,Nanni P,Lollini PL,Musiani P,Di Carlo E,Bulanova E,Paus R,Bulfone-Paus S

更新日期：2002-05-01 00:00:00

abstract：:The pair of microH-chain and kappa L-chain transgenes encoding the Sp6 TNP/DNA-specific IgM was bred onto the rearrangement-deficient genetic background of RAG-2T mice, and onto the kappa L-chain expression-deficient background of iE kappa T mice. Bone marrow of Sp6 transgenic RAG-2T mice contained normal numbers of B...

journal_title：Scandinavian journal of immunology

authors： Andersson J,Melchers F,Rolink A

更新日期：1995-07-01 00:00:00

abstract：:We have analysed separately the role of B-cell receptor (BCR) stimulation and the soluble second signal in the T-cell-independent type 2 (TI-2) B-cell response. We were able to show that human B cells and macrophages (Mphi) could function together in TI-type microbial response. Interestingly, BCR cross-linking of peri...

journal_title：Scandinavian journal of immunology

authors： Mättö M,Raunio AR,Postila V,Huttunen K,Hirvonen MR,Pelkonen J

更新日期：2008-03-01 00:00:00

abstract：:The authors have established a new immunodeficient mouse strain on the genetic background of the diabetes prone non-obese diabetic (NOD) mouse. A deletion mutant of the RAG-2 gene was back crossed 10 generations onto the NOD/Bom strain background. The homozygous NODrag-2-/- mice lack functionally mature B and T lympho...

journal_title：Scandinavian journal of immunology

authors： Söderstrøm I,Bergman ML,Colucci F,Lejon K,Bergqvist I,Holmberg D

更新日期：1996-05-01 00:00:00

abstract：:Here we analyse the ability of soluble immune complexes (IC) prepared with cationized antibodies to induce cytotoxic responses mediated by neutrophils. While cationized IC induced high levels of cytotoxicity, control IC induced very low levels of response. Inhibition of cytotoxicity by catalase but not by three haemen...

journal_title：Scandinavian journal of immunology

authors： Geffner JR,Trevani AS,Malchiodi E,Serebrinsky GP,Isturiz MA

更新日期：1993-02-01 00:00:00

abstract：:The build-up of long-term immunological memory in the gut mucosal immune system may explain long-lasting protection against new attacks of cholera in convalescents from natural disease. We have looked for gut mucosal antitoxin immunological memory and memory cells in mice after oral immunization with cholera toxin. Ou...

journal_title：Scandinavian journal of immunology

authors： Lycke N,Holmgren J

更新日期：1986-05-01 00:00:00

abstract：:The restriction fragment length polymorphism of the human tumour necrosis factor (TNF alpha) region was investigated by means of 20 different restriction enzymes and a human TNF alpha cDNA probe. Only one of the enzymes, NcoI, revealed a polymorphic pattern consisting of fragments of 10.5 and 5.5 kb, which behaved as ...

journal_title：Scandinavian journal of immunology

authors： Fugger L,Morling N,Ryder LP,Platz P,Georgsen J,Jakobsen BK,Svejgaard A,Dalhoff K,Ranek L

更新日期：1989-08-01 00:00:00

abstract：:Infection with murine gammaherpesvirus 68 has become an accepted model for studying the virus/host interactions with regard to gammaherpesvirus infections. Previous studies using gene-deficient mice have revealed that neither IFNγ nor perforin is essential in controlling the outcome of infection or the virus load duri...

journal_title：Scandinavian journal of immunology

authors： Bartholdy C,Høgh-Petersen M,Storm P,Holst PJ,Orskov C,Christensen JP,Thomsen AR

更新日期：2014-06-01 00:00:00

abstract：:Physiological ageing is accompanied by decline in immune system function and immune alteration during ageing increases susceptibility to infections. We retrospectively analysed the data for complete blood count (CBC) and lymphocyte subsets from infant to elderly age groups to determine changes during ageing. Data from...

journal_title：Scandinavian journal of immunology

authors： Valiathan R,Ashman M,Asthana D

更新日期：2016-04-01 00:00:00

abstract：:In a previous work the authors demonstrated that immunization with Schistosoma mansoni 28-kDa glutathione-S-transferase (Sm28GST) was able to reduce hepatic damage in infected mice and that the adoptive transfer of Sm28GST-specific T cells reproduced the protective effect obtained with the recombinant molecule. In the...

journal_title：Scandinavian journal of immunology

authors： Pancré V,Gras-Masse H,Delanoye A,Herno J,Capron A,Auriault C

更新日期：1996-11-01 00:00:00

abstract：:Transgenic techniques in inbred mouse strains are powerful tools to investigate the specific roles of genes in biological pathways and disease models. However, there is increasing concern over the influence of a variable genetic background in such experiments. To date there have been few investigations of the immunolo...

journal_title：Scandinavian journal of immunology

authors： Johansson AC,Vestberg M,Holmdahl R

更新日期：2000-07-01 00:00:00

abstract：:Propagermanium is an organic germanium compound with immunopotentiating activity. We examined the hepatoprotective effect of propagermanium and its mechanism in an experimental animal model of acute liver injury induced with Corynebacterium parvum (C. parvum) and lipopolysaccharide (LPS) injection. Oral pretreatment w...

journal_title：Scandinavian journal of immunology

authors： Yokochi S,Ishiwata Y,Hashimoto H,Ninomiya F,Suzuki T

更新日期：1998-08-01 00:00:00

abstract：:Pemphigus vulgaris is a cutaneous autoimmune disease in which the occurrence of autoantibodies directed against desmoglein-3 and other self-antigens has been well established in patient sera. However, V-region interactions (connectivity) of serum IgG and IgM have not been analysed to date. In this report, it has been ...

journal_title：Scandinavian journal of immunology

authors： Pacheco-García U,Tovar-Rivera T,Padierna-Olivos L,Rojas-Espinosa O,Sánchez-Colón S,Gutiérrez-Armenta M,Rivera-Benítez C,Masso-Rojas F,Sánchez-García FJ

更新日期：1999-04-01 00:00:00

abstract：:The present investigation was designed to determine whether the heavy or the light immunoglobulin chain is involved in the non-immune binding of IgG F(ab')2 fragments to specific surface receptors on human group C and G streptococci. Purified human polyclonal IgG was mildly reduced with dithiothreitol and alkylated wi...

journal_title：Scandinavian journal of immunology

authors： Erntell M,Myhre EB,Kronvall G

更新日期：1985-02-01 00:00:00

abstract：:In a well-established murine abortion model, stress is thought to trigger fetal rejection by inducing a proinflammatory immune response via substance P (SP), being tumour necrosis factor (TNF)-alpha-producing CD8+ T cells involved. Interestingly, the SP metabolite SP5-11 also binds to SP receptors and mediates SP-like...

journal_title：Scandinavian journal of immunology

authors： Fest S,Zenclussen AC,Joachim R,Hagen E,Demuth HU,Hoffmann T

更新日期：2006-01-01 00:00:00

abstract：:Human endothelial cells (EC), cultured serum-free, synthesize de novo protein which increasingly bind to agarose beads (an alternative pathway activator), until a plateau phase is reached after 24-48 h. EC synthesize functional C3, C5, C6, C8 and C9, which were detected on co-cultured agarose beads, using relevant pol...

journal_title：Scandinavian journal of immunology

authors： Johnson E,Hetland G

更新日期：1991-06-01 00:00:00

abstract：:Purified human amyloid protein A (AA) or serum amyloid protein A (SAA) was incubated with normal human high-density lipoprotein (HDL). After ultracentrifugation the amount of AA or SAA associated with HDL was measured. It was found that the binding capacity of HDL for SAA was higher than that for AA. Incubation of the...

journal_title：Scandinavian journal of immunology

authors： Husebekk A,Skogen B,Husby G

更新日期：1988-12-01 00:00:00

abstract：:The CD45 molecule is a transmembrane tyrosine phosphatase that may be associated with the T-cell receptor (TCR). This has led to the suggestion that CD45 may be important for the regulation of signal transduction in T cells. This idea is supported by the finding that antibodies against CD45 are comitogenic in prolifer...

journal_title：Scandinavian journal of immunology

authors： Wolff H,Janeway C Jr

更新日期：1994-07-01 00:00:00

abstract：:There is convincing evidence that certain combinations of alleles within the human leucocyte antigen (HLA) complex, particularly within HLA-DQ, are associated with either resistance or susceptibility to insulin-dependent diabetes mellitus (IDDM). A previous study conducted on a large, well-defined group of patients de...

journal_title：Scandinavian journal of immunology

authors： Baisch JM,Capra JD

更新日期：1992-08-01 00:00:00

abstract：:Polymorphonuclear cell function tests were performed in 340 patients with recurrent unexplained infections. Serum-dependent defects in phagocytosis and intracellular killing of Candida albicans (Candida opsonin and procidin defects) were specifically associated with susceptibility to recurrent pyogenic infections, Can...

journal_title：Scandinavian journal of immunology

authors： Parkin JM,Bridges J,Sloper KS,Warner JO,Pinching AJ

更新日期：1991-01-01 00:00:00

abstract：:Immunoglobulin D (IgD) is the least studied of immunoglobulin classes. This study sought to investigate the potential relationship between demographic, metabolic, lifestyle and immunological factors, and serum IgD concentrations in a general adult population. We measured serum IgD concentrations by means of a commerci...

journal_title：Scandinavian journal of immunology

authors： Carballo I,Rabuñal N,Alvela L,Pérez LF,Vidal C,Alonso M,Sopeña B,Gude F,Gonzalez-Quintela A

更新日期：2017-04-01 00:00:00

abstract：:Native agarose beads (diameter 5-10 micron), activators of the alternative complement pathway, are slowly phagocytosed when incubated with human monocytes cultured under serum-free conditions. Agarose beads preincubated with monocyte cultures and then transferred to new cultures are more easily phagocytosed than nativ...

journal_title：Scandinavian journal of immunology

authors： Hetland G,Eskeland T

更新日期：1986-03-01 00:00:00

abstract：:This study investigates local alterations in T-cell and macrophage subsets that occur in cervical epithelial neoplasia (CIN), in the presence and absence of human immunodeficiency virus (HIV) infection. Ectocervical biopsies from 10 women with CIN who were infected with HIV, and 10 women with CIN but no HIV infection ...

journal_title：Scandinavian journal of immunology

authors： Ahmed SM,Al H,Reid WM,Johnson MA,Poulter LW

更新日期：2002-08-01 00:00:00