Alternating chemotherapy with cyclophosphamide/adriamycin/vincristine (CAV) and cisplatin/etoposide (PVP) against small cell lung cancer. Eastern Shikoku Lung Cancer Chemotherapy Group.

abstract：:Human lymphoblastoid interferon-alpha was administered intramuscularly at a dose of 5 x 10(6) units/day to 20 metastatic renal cell carcinoma patients. For potentiating the antitumor effect of interferon, cimetidine was also given to them orally at a dose of 800 mg/day. The combination therapy obtained a complete resp...

journal_title：Japanese journal of clinical oncology

authors： Kotake T,Kinouchi T,Saiki S,Kuroda M,Miki T,Kiyohara H,Usami M

更新日期：1991-02-01 00:00:00

abstract：:Seventy metastatic breast adenocarcinoma patients, pretreated with standard hormonotherapy or chemotherapy, received continuous UFT at 10 mg/kg/day, orally, for at least two months. There were one complete response (1.5%), 12 partial responses (17%), one minor response and 37 disease stabilizations. The median duratio...

journal_title：Japanese journal of clinical oncology

authors： Daniels M,Díaz-Rubio E,Guillem V,Montero JM,García-Conde J,Estapé J,Martín M,Herranz C,Ordoñez A,Galán A

更新日期：1993-12-01 00:00:00

abstract：:Peripheral plasma prostaglandins (PGs) were assayed in 10 cases of gynecologic malignancies. In addition, fluctuations of PG levels during chemotherapeutically-induced gastrointestinal toxicity as well as those caused by a bolus infusion of steroid hormone were investigated. As a result, the level of PGE2 in most case...

journal_title：Japanese journal of clinical oncology

authors： Suzuki M,Ohwada M,Tamada T

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:Despite the clinical similarities triple-negative and basal-like breast cancer are not synonymous. Indeed, not all basal-like cancers are negative for estrogen receptor, progesterone receptor and HER2 expression while triple-negative also encompasses other cancer types. P53 protein appears heterogeneously exp...

journal_title：Japanese journal of clinical oncology

authors： Biganzoli E,Coradini D,Ambrogi F,Garibaldi JM,Lisboa P,Soria D,Green AR,Pedriali M,Piantelli M,Querzoli P,Demicheli R,Boracchi P,Nenci I,Ellis IO,Alberti S

更新日期：2011-02-01 00:00:00

abstract：:Advanced esophageal cancer patients with extensive lymph node metastases show extremely poor prognosis and the long-term outcome is poorer with the involvement of more lymph nodes. We report here a long-surviving case of advanced esophageal cancer with histologically 34 lymph node metastases, in which surgical resecti...

journal_title：Japanese journal of clinical oncology

authors： Shigemitsu K,Naomoto Y,Shirakawa Y,Haisa M,Gunduz M,Tanaka N

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:We conducted a dose-finding and feasibility study in which we administered a fixed dose 3-h infusion of paclitaxel and an escalating dose of cisplatin in Japanese patients with advanced non-small cell lung cancer. METHODS:Chemotherapy consisted of fixed dose (210 mg/m(2)) paclitaxel given over 3 h on day 1 ...

journal_title：Japanese journal of clinical oncology

authors： Watanabe H,Yamamoto N,Tamura T,Shimoyama T,Hotta K,Inoue A,Sawada M,Akiyama Y,Kusaba H,Nokihara H,Sekine I,Kunitoh H,Ohe Y,Kodama T,Saijo N

更新日期：2003-12-01 00:00:00

abstract：Background:Few studies have simultaneously collected quantitative data regarding the positive and negative effects of participating in post-bereavement surveys. Methods:We conducted a cross-sectional postal questionnaire survey in October 2013. Potential participants were caregivers for family members who had died in ...

journal_title：Japanese journal of clinical oncology

authors： Miyashita M,Aoyama M,Yoshida S,Yamada Y,Abe M,Yanagihara K,Shirado A,Shutoh M,Okamoto Y,Hamano J,Miyamoto A,Nakahata M

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To clarify the association between pre-treatment total bilirubin (PTB) level and severe toxicity in patients receiving cisplatin and irinotecan. METHODS:We analyzed retrospectively the relationships of grade 4 neutropenia or grade 3-4 diarrhea and clinical variables including PTB and pre-treatment neutrophil...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara Y,Sekine I,Ohe Y,Kunitoh H,Yamamoto N,Nokihara H,Simmyo Y,Fukui T,Yamada K,Tamura T

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Colorectal cancer is one of the most common carcinomas observed in humans. Recently we have reported that increased oxidative stress is associated with human colorectal cancer. There are few and controversial studies on the clinical relevance of the expression of heat shock protein 70 (HSP 70), a member of t...

journal_title：Japanese journal of clinical oncology

authors： Ozdemirler Erata G,Kanbağli O,Durlanik O,Bulut T,Toker G,Uysal M

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:A self-administered quantitative food frequency questionnaire (Qx) was developed for a population-based cohort study on cancer in Takayama, Japan. METHODS:The Qx was tested among 58 male and 59 female volunteers. Average daily nutrient intakes for the previous year calculated from the Qx were compared with ...

journal_title：Japanese journal of clinical oncology

authors： Shimizu H,Ohwaki A,Kurisu Y,Takatsuka N,Ido M,Kawakami N,Nagata C,Inaba S

更新日期：1999-01-01 00:00:00

abstract：:Subglottic carcinoma is rare and has a poor prognosis. It is usually treated with surgical resection, external beam irradiation (EBR) and/or a combination of both. Intraluminal irradiation (IR) as a curative treatment for subglottic carcinoma has never been reported. We report a case of subglottic carcinoma in a 66-ye...

journal_title：Japanese journal of clinical oncology

authors： Wakisaka M,Fuwa N,Matsumoto A,Tachibana H,Kodaira T,Furutani K,Kamata M,Mori H

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:This multicenter, open-label, single-arm, Phase II study assessed the efficacy of a neoadjuvant chemotherapy with docetaxel (75 mg/m(2) q3w) followed by 5-fluorouracil 500 mg/m(2), epirubicin 100 mg/m(2) and cyclophosphamide 500 mg/m(2) q3w in patients with early-stage breast cancer. METHODS:Women with resec...

journal_title：Japanese journal of clinical oncology

authors： Iwata H,Sato N,Masuda N,Nakamura S,Yamamoto N,Kuroi K,Kurosumi M,Tsuda H,Akiyama F,Ohashi Y,Toi M

更新日期：2011-07-01 00:00:00

abstract：:In Japan, lateral lymph node dissection (LLND) is generally performed for the treatment of T3-4 lower rectal carcinoma, and not for T1 lower rectal carcinoma, because of a low positive rate in patients with T1 lesion. We experienced a rare case of lateral pelvic lymph node recurrence after total mesorectal resection f...

journal_title：Japanese journal of clinical oncology

authors： Hara J,Yamamoto S,Fujita S,Akasu T,Moriya Y

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare tumor usually diagnosed at an advanced stage on invasion of or adherence to adjacent organs. We report surgical outcome of stage III and IV ACCs. METHODS:ACCs from seven patients at clinical stage II (n = 1), III (n = 4), or IV (n = 2) were resected. Combined resecti...

journal_title：Japanese journal of clinical oncology

authors： Ohwada S,Izumi M,Kawate S,Hamada K,Toya H,Togo N,Horiguchi J,Koibuchi Y,Takahashi T,Yamada M

更新日期：2007-02-01 00:00:00

abstract：:AMG 337, a selective small-molecule MET inhibitor, was evaluated in Asian patients with advanced solid tumors. Eligible patients orally self-administered AMG 337; the initial dose of 150 mg once daily (QD) was escalated to 300 mg QD (modified 3+3+3 design). Treatment continued until disease progression, intolerability...

journal_title：Japanese journal of clinical oncology

authors： Yasui H,Go N,Yang H,Amore BM,Jung AS,Doi T

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:As clinical trials for limited-disease small-cell lung cancer often exclude elderly patients due to comorbidities and a decline in organ function, the most suitable treatment for limited-disease small-cell lung cancer patients aged 75 years or older still remains unclear. METHODS:From July 2002 to June 2011...

journal_title：Japanese journal of clinical oncology

authors： Shukuya T,Takahashi T,Harada H,Ono A,Akamatsu H,Taira T,Kenmotsu H,Naito T,Murakami H,Endo M,Takahashi K,Yamamoto N

更新日期：2013-02-01 00:00:00

abstract：:Although recent progress in multi-drug chemotherapy has increased the median survival of patients with extensive Small cell lung cancer (SCLC) to 7 months, 2-year survivors are still exceptional. We describe a 40-year-old man with extensive SCLC involving the lungs and systemic nodes who was initially treated with 6 c...

journal_title：Japanese journal of clinical oncology

authors： Shimizu E,Takaue Y,Yamamoto A,Ogura T,Sone S

更新日期：1995-10-01 00:00:00

abstract：:To elucidate the relationship between the clinical features and pathologic findings of primary pulmonary lymphoma, we reviewed 24 patients with this disease. The pulmonary lymphomas were divided into four groups: (1) B-cell lymphoma composed of small to medium-sized lymphoid cells (19 cases); (2) B-cell lymphoma compo...

journal_title：Japanese journal of clinical oncology

authors： Tamura A,Komatsu H,Yanai N,Homma J,Nagase A,Nemoto E,Hirai T,Hashizume T,Kawata K,Ishikawa S

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:This study was performed to review retrospectively the clinical course of chronic rectal bleeding as a complication of external beam radiation therapy for localized prostate cancer and to analyze the relationship between technical parameters of radiation therapy and the complications. METHODS:Seventy-one pa...

journal_title：Japanese journal of clinical oncology

authors： Kitamura K,Shirato H,Suzuki K,Shinohara N,Demura T,Harabayashi T,Nishioka T,Kagei K,Takayama N,Shinno Y,Kawakura K,Koyanagi T,Miyasaka K

更新日期：2000-05-01 00:00:00

abstract：:Sarcoma of the hypopharynx has been reported very rarely in the literature, only six cases having been found among all head and neck malignancies reported to SEER (Surveillance, Epidemiology, and End Results) during 1973-1987. We report a 14-year-old boy with a huge malignant soft tissue sarcoma arising from the hypop...

journal_title：Japanese journal of clinical oncology

authors： Lin JC,Hsu CY,Kwan PC,Shen WC,Jan JS,Ho WL

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:Second primary malignancies have become the leading cause of death in retinoblastoma survivors. Although osteosarcoma is the most common second malignancy, little is known about its clinical and therapeutic features. METHODS:We retrospectively reviewed a database of patients with retinoblastoma and osteosarc...

journal_title：Japanese journal of clinical oncology

authors： Fujiwara T,Fujiwara M,Numoto K,Ogura K,Yoshida A,Yonemoto T,Suzuki S,Kawai A

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:In an interim analysis of a Phase II trial in Japanese patients with pancreatic neuroendocrine tumors (panNETs), sunitinib demonstrated antitumor activity with an objective response rate (ORR) of 50% (95% confidence interval [CI], 21-79) and a median progression-free survival (PFS) of 16.8 months (95% CI, 9....

journal_title：Japanese journal of clinical oncology

authors： Ito T,Tori M,Hashigaki S,Kimura N,Sato K,Ohki E,Sawaki A,Okusaka T

更新日期：2019-04-01 00:00:00

abstract：:Case 1: A 14-year-old boy with nasopharyngeal cancer (T4N0M0) was treated with stereotactic radiosurgery (SRS) as a boost therapy after conventional radiotherapy. Persistent residual tumor visible with MR remained after conventional radiotherapy comprising 59.6 Gy in total. We therefore performed SRS to add a further ...

journal_title：Japanese journal of clinical oncology

authors： Yokouchi J,Satani K,Kanesaka N,Abe K,Hasegawa T

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Phase I oncology trials have raised concerns that patients' 'unrealistic' optimism could compromise the validity of informed consent, and that patients often participate in trials to conform to physicians' or family members' recommendations. We aimed to determine whether patients or families-given the same in...

journal_title：Japanese journal of clinical oncology

authors： Shin DW,Cho J,Kim SY,Yang HK,Cho B,Shin DB,Chun MS,Min YJ,Kim YW,Park JH

更新日期：2016-12-01 00:00:00

abstract：:The clinical, hematological and pathological features of the adult T-cell leukemia (ATL)-related diseases and their cell membrane phenotypes in the Nagasaki district, one of the ATL-endemic areas, were delineated to compare them with those of adult T-cell leukemia-lymphoma (ATLL). In addition, the participation of ATL...

journal_title：Japanese journal of clinical oncology

authors： Kinoshita K,Amagasaki T,Yamada Y,Ikeda S,Momita S,Toriya K,Kamihira S,Ichimaru M

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to re-evaluate post-remission therapy outcomes after first remission according to years of patient enrollment in patients with core binding factor acute myeloid leukaemia. METHODS:We conducted a retrospective study on 138 patients aged less than 60 years diagnosed with core bind...

journal_title：Japanese journal of clinical oncology

authors： Shin HJ,Kim HJ,Sohn SK,Min YH,Won JH,Kim I,Yoon HJ,Lee JH,Jo DY,Joo YD,Jung CW,Lee KH,Korean Society of Hematology, AML\/MDS Working Party.,Chung JS,Ahn JS,Kim SJ,Lee JH,Choi SJ,Lee JH,Bae SH,Hong DS,Zang DY,K

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The Patterns of Care Study (USPCS) by the American College of Radiology (ACR) has made significant contributions to improvements in the procedures of care for patients with breast cancer in the USA. The purpose of this study was to identify problems associated with the process of care for patients undergoing...

journal_title：Japanese journal of clinical oncology

authors： Shikama N,Nishikawa A,Mitsumori M,Hiraoka M,Yamamoto T,Teshima T,Inoue T,Wilson F,Owen J

更新日期：2003-10-01 00:00:00

abstract：:Alendronate, a bisphosphonate compound, lowers serum calcium in patients with cancer-associated hypercalcemia through its inhibitory effect on bone resorption and as a result symptoms associated with hypercalcemia improve. This study was carried out to investigate the effects of alendronate in patients with hypercalce...

journal_title：Japanese journal of clinical oncology

authors： Ohnishi T,Takeda E,Yogita S,Miyake H,Kinoshita T,Terashima Y,Matsumoto T,Tashiro S

更新日期：2000-09-01 00:00:00

abstract：Objective:This study aims to reveal the present situation of changes in physical appearance induced by treatment, the effects of these changes on social activities, and support from medical staff in male cancer patients. Methods:A questionnaire survey was administered to 949 male patients (response rate: 90.1%) visiti...

journal_title：Japanese journal of clinical oncology

authors： Nozawa K,Tomita M,Takahashi E,Toma S,Arai Y,Takahashi M

更新日期：2017-08-01 00:00:00

abstract：:Most terminally ill cancer patients in our hospice ward are referred from hospitals for anticancer treatment. For identical terminally ill cancer patients referred from other hospitals, differences in the accuracy and characteristics of the prognostic prediction of survival by oncologists and palliative care physician...

journal_title：Japanese journal of clinical oncology

authors： Urahama N,Sono J,Yoshinaga K

更新日期：2018-07-01 00:00:00