The ultrastructure of MCF-10A acini.

abstract：:Urotensin II (UII), a vasoactive peptide modulates renal hemodynamics. However, the physiological functions of UII in glomerular cells are unclear. In particular, whether UII alters mesangial tone remains largely unknown. The present study investigates the physiological effects of UII on glomerular mesangial cells (GM...

journal_title：Journal of cellular physiology

authors： Adebiyi A

更新日期：2014-04-01 00:00:00

abstract：:Therapeutic application of stem cells and oncolytic viruses in cancer treatment has rapidly increased in the last decade. Oncolytic viruses are considered as a new class of anticancer agents because of their ability to selectively infect and destroy cancer cells. Furthermore, regarding the specific migratory capacity ...

journal_title：Journal of cellular physiology

authors： Zendedel E,Atkin SL,Sahebkar A

更新日期：2019-02-15 00:00:00

abstract：:A human osteosarcoma cell line, U-2 OS, cultured under serum-free conditions, was shown to produce a growth factor (osteosarcoma-derived growth factor, ODGF) for human-cultured glial cells, fibroblasts, and other cells. ODGF, collected from the spent medium of 2 OS cultures, was purified by a sequence involving hepari...

journal_title：Journal of cellular physiology

authors： Heldin CH,Westermark B,Wasteson A

更新日期：1980-11-01 00:00:00

abstract：:Biochemical events elicited by interleukin 1 (IL-1) were studied in Swiss 3T3 fibroblasts. One hour after its addition, IL-1 stimulated synthesis of prostaglandin E2 (PGE2), which continued to accumulate for 4 days. IL-1 also stimulated cAMP accumulation. Indomethacin blocked cAMP accumulation in response to IL-1, sug...

journal_title：Journal of cellular physiology

authors： Burch RM,White MF,Connor JR

更新日期：1989-04-01 00:00:00

abstract：:NEMO/IKKγ is the regulatory subunit of the IκB Kinase (IKK) complex, required for the activation of the NF-κB pathway, which is involved in a variety of key processes, including immunity, inflammation, differentiation, and cell survival. Termination of NF-κB activity on specific -κB responsive genes, which is crucial ...

journal_title：Journal of cellular physiology

authors： Esposito E,Napolitano G,Pescatore A,Calculli G,Incoronato MR,Leonardi A,Ursini MV

更新日期：2016-01-01 00:00:00

abstract：:Nicotinamide adenine dinucleotide phosphate [NAD(P)H] oxidase complex has been shown to be involved in the process of glucose-stimulated insulin secretion (GSIS). In this study, we examined the effect of palmitic acid on superoxide production and insulin secretion by rat pancreatic islets and the mechanism involved. R...

journal_title：Journal of cellular physiology

authors： Graciano MF,Santos LR,Curi R,Carpinelli AR

更新日期：2011-04-01 00:00:00

abstract：:Interleukin-34 (IL-34) shares a common receptor with macrophage colony-stimulating factor (M-CSF), and can bind to CSF-1R, induces lymphocytes differentiation, proliferation, and regulates the synthesis of inflammatory components. Recent findings reported aberrant expression of IL-34 in several autoimmune disorders, s...

journal_title：Journal of cellular physiology

authors： Xu WD,Huang AF,Fu L,Liu XY,Su LC

更新日期：2019-12-01 00:00:00

abstract：:Cancer cells acquire dysregulated gene expression to establish specific transcriptional dependencies and their underlying mechanisms that are ultimately responsible for this addictions have not been fully elucidated. Glucose-regulated protein 78 (GRP78) is a stress-inducible, multifunctional, prosurvival, endoplasmic ...

journal_title：Journal of cellular physiology

authors： Gopal U,Pizzo SV

更新日期：2020-08-31 00:00:00

abstract：:An analysis of which component of lipopolysaccharides (LPS), the lipid or the polysaccharide (PS), is active in stimulating the murine granulopoietic system has been performed. LPS with different structures, isolated from different mutant strains of Salmonella and chemical degradation products of lipopolysaccharides h...

journal_title：Journal of cellular physiology

authors： Apte RN,Galanos C,Pluznik DH

更新日期：1976-01-01 00:00:00

abstract：:Serine racemase (SR) is responsible for the biosynthesis of D-serine (D-Ser), an endogenous co-agonist for the glycine (Gly)-binding site on N-methyl-D-aspartate (NMDA) receptors, from L-Ser in the brain. We have previously demonstrated high expression of SR by chondrocytes in cartilage. In this study, we attempted to...

journal_title：Journal of cellular physiology

authors： Takarada T,Takahata Y,Iemata M,Hinoi E,Uno K,Hirai T,Yamamoto T,Yoneda Y

更新日期：2009-09-01 00:00:00

abstract：:We have previously shown that knockout of fibroblast growth factor-2 (FGF-2) and potential compensatory effects of other growth factors result in amelioration of disease symptoms in a transgenic mouse model of amyotrophic lateral sclerosis (ALS). ALS is a rapidly progressive neurological disorder leading to degenerati...

journal_title：Journal of cellular physiology

authors： Kefalakes E,Böselt S,Sarikidi A,Ettcheto M,Bursch F,Naujock M,Stanslowsky N,Schmuck M,Barenys M,Wegner F,Grothe C,Petri S

更新日期：2019-05-01 00:00:00

abstract：:Cancer-associated fibroblasts (CAFs) in the tumor microenvironment play major roles in supporting cancer progression. A previous report showed that SPIN90 downregulation is correlated with CAF activation and that SPIN90-deficient CAFs promote breast cancer progression. However, the mechanisms that mediate cancer-strom...

journal_title：Journal of cellular physiology

authors： Kwon A,Chae IH,You E,Kim SH,Ahn SY,Lee OJ,Park ZY,Rhee S,Huh YH,Song WK

更新日期：2020-05-01 00:00:00

abstract：:We have examined nucleoside transport (NT) in a cell line derived from primary day 7 murine bone marrow macrophages (S1 macrophages) in response to the macrophage growth factor, colony-stimulating factor 1 (CSF-1). Adenosine and uridine transport in quiescent S1 macrophages occurred primarily by two facilitated diffus...

journal_title：Journal of cellular physiology

authors： Meckling-Gill KA,Guilbert L,Cass CE

更新日期：1993-06-01 00:00:00

abstract：:Parkinsonism is one of the most common aging neurodegenerative disorders. This study aims to compare the therapeutic effect of stem cell versus its conditioned medium in the Parkinsonism model. Parkinsonism was induced by daily subcutaneous injection of 0.5 mg/kg of rotenone dissolved in dimethyl sulfoxide for 28 days...

journal_title：Journal of cellular physiology

authors： Abdelwahab S,Elsebay SAG,Fouli Gaber M,Abdel-Hafez SMN

更新日期：2021-01-01 00:00:00

abstract：:Histone deacetylases (HDACs) play a crucial role in the regulation of gene expression through remodeling of chromatin structures. However, the molecular mechanisms involved in this event remain unknown. In this study, we sought to examine whether HDAC inhibition-mediated protective effects involved HDAC4 sumoylation, ...

journal_title：Journal of cellular physiology

authors： Du J,Zhang L,Zhuang S,Qin GJ,Zhao TC

更新日期：2015-06-01 00:00:00

abstract：:Mesenchymal stem/stromal cells (MSCs) have gained considerable popularity owing to the vast possibilities and lack of ethical constraints and risks normally associated with other stem cells, such as embryonic stem cells. However, they are morphologically indistinguishable from fibroblasts. This review aims to assess t...

journal_title：Journal of cellular physiology

authors： Soundararajan M,Kannan S

更新日期：2018-12-01 00:00:00

abstract：:BP3T3, a clonal benzo(a)pyrene-transformed BALB/c-3T3 cell line, is conditionally responsive to growth factor stimulation. Density arrested cell populations deprived of growth factors by pretreatment with 0.5% platelet-poor plasma synthesized DNA both in response to ng/ml concentrations of PDGF, EGF, and somatomedin C...

journal_title：Journal of cellular physiology

authors： Whipple AP,Furlanetto RW,Scher CD

更新日期：1987-02-01 00:00:00

abstract：:Recent studies have indicated that endoplasmic reticulum stress, the unfolded protein response activation and altered GRP78 expression can play an important role in a variety of tumors development and progression. Very recently we reported for the first time that GRP78 is increased in endometrial tumors. However, whet...

journal_title：Journal of cellular physiology

authors： Calì G,Insabato L,Conza D,Bifulco G,Parrillo L,Mirra P,Fiory F,Miele C,Raciti GA,Di Jeso B,Terrazzano G,Beguinot F,Ulianich L

更新日期：2014-10-01 00:00:00

abstract：:In order to study the generation, factors controlling endogenous folate pools, and their functional importance, Friend erythroleukemia cells were grown in media containing 100; 1,000; and 10,000 ng/ml of tritiated pteroylglutamic acid (3H)PteGlu1 and then studied in unlabeled media with varying amounts of PteGlu1. The...

journal_title：Journal of cellular physiology

authors： Steinberg SE,Fonda S,Campbell CL,Hillman RS

更新日期：1983-02-01 00:00:00

abstract：:Sepsis, a complex and dynamic syndrome resulting from microbial invasion and immune system dysregulation, is associated with an increased mortality, reaching up to 35% worldwide. Cholesterol metabolism is often disturbed during sepsis, with low plasma cholesterol levels being associated with poor prognosis. Proprotein...

journal_title：Journal of cellular physiology

authors： Paciullo F,Fallarino F,Bianconi V,Mannarino MR,Sahebkar A,Pirro M

更新日期：2017-09-01 00:00:00

abstract：:Silibinin is the primary active compound in silymarin. It has been demonstrated to exert anti-carcinogenic effects and hepato-protective effects. However, the effects of silibinin on the maturation and immunostimulatory activities exhibited by dendritic cells (DCs) remain, for the most part, unknown. In this study, we...

journal_title：Journal of cellular physiology

authors： Lee JS,Kim SG,Kim HK,Lee TH,Jeong YI,Lee CM,Yoon MS,Na YJ,Suh DS,Park NC,Choi IH,Kim GY,Choi YH,Chung HY,Park YM

更新日期：2007-02-01 00:00:00

abstract：:Recent studies have suggested that interferons (IFNs) have an antifibrotic effect in the liver independent of their antiviral effect although its detailed mechanism remains largely unknown. Some microRNAs have been reported to regulate pathophysiological activities of hepatic stellate cells (HSCs). We performed analys...

journal_title：Journal of cellular physiology

authors： Sekiya Y,Ogawa T,Iizuka M,Yoshizato K,Ikeda K,Kawada N

更新日期：2011-10-01 00:00:00

abstract：:A temperature-sensitive mutant with a defect in glycoprotein synthesis and a cell cycle (G1)-specific arrest at the nonpermissive temperature (Tenner et al., J. Cell. Physiol., 90:145-160, 1977; Tenner and Scheffler, J. Cell. Physiol., 98:251-266, 1979) was investigated further after a human epidermal growth factor (E...

journal_title：Journal of cellular physiology

authors： Feige JJ,Scheffler IE

更新日期：1987-12-01 00:00:00

abstract：:Established RAW264.7 cell lines for osteoclastic differentiation has been widely engaged in bone homeostasis research, however, the efficacy of RANKL independently stimulating has rarely been defined, because protocols were usually developed and modified by various laboratories. Otherwise, problematic issues are also ...

journal_title：Journal of cellular physiology

authors： Song C,Yang X,Lei Y,Zhang Z,Smith W,Yan J,Kong L

更新日期：2019-07-01 00:00:00

abstract：:CRSBP-1 (mammalian LYVE-1) is a membrane glycoprotein highly expressed in lymphatic endothelial cells (LECs). It has multiple ligands, including hyaluronic acid (HA) and growth factors/cytokines (e.g., PDGF-BB and VEGF-A) containing CRS motifs (clusters of basic amino-acid residues). The ligand binding activities are ...

journal_title：Journal of cellular physiology

authors： Huang SS,Li YW,Wu JL,Johnson FE,Huang JS

更新日期：2018-04-01 00:00:00

abstract：:In fertilized echinoderm eggs, the male and female pronuclei fuse to form the diploid nucleus even in the presence of aphidicolin, a specific inhibitor of eukaryotic DNA polymerase-alpha. The subsequent first cleavage is independent of chromosomes but dependent on spindle and amphiaster. The fate of DNA originally exi...

journal_title：Journal of cellular physiology

authors： Yamada H,Hirai S,Ikegami S,Kawarada Y,Okuhara E,Nagano H

更新日期：1985-07-01 00:00:00

abstract：:The mechanisms by which mature myeloid cells are released from the bone marrow into the peripheral blood are not clearly understood. Glycosylation is likely to play an important role, as has been shown in the homing of lymphocytes to lymph nodes and of neutrophils to inflamed endothelia. Cell surface sialylation is an...

journal_title：Journal of cellular physiology

authors： Le Marer N,Skacel PO

更新日期：1999-06-01 00:00:00

abstract：:The polyphenolic compounds curcumin and quercetin increased sensitivity of ovarian cancer cells (CAOV3 and SKOV3) to cisplatin. The effect was obtained when the compounds were added simultaneously with cisplatin, as well as when they were added 24 h before. High serum levels of certain cytokines, for example interleuk...

journal_title：Journal of cellular physiology

authors： Chan MM,Fong D,Soprano KJ,Holmes WF,Heverling H

更新日期：2003-01-01 00:00:00

abstract：:A basic understanding of the recruitment of quiescent tumor cells into the cell cycle would be an important contribution to tumor biology and therapy. As a first step in pursuing this goal, we have investigated the regrowth kinetics of cells from different regions in multicellular spheroids of rodent and human origin....

journal_title：Journal of cellular physiology

authors： Freyer JP,Schor PL

更新日期：1989-02-01 00:00:00

abstract：:There is strong evidence that thyroid hormones through triiodothyronine (T3) regulate Sertoli cell proliferation and differentiation in the neonatal testis. However, the mechanism(s) by which they are able to control Sertoli cell proliferation is unclear. In the present study in vivo approaches (PTU-induced neonatal h...

journal_title：Journal of cellular physiology

authors： Gilleron J,Nebout M,Scarabelli L,Senegas-Balas F,Palmero S,Segretain D,Pointis G

更新日期：2006-10-01 00:00:00