A potential novel mechanism involving connexin 43 gap junction for control of sertoli cell proliferation by thyroid hormones.

abstract：:Cultivation of human parotid glands in serum-free medium (Ca(2+) concentration, 0.2 mM) with growth supplements resulted in isolation of a homogeneous population of epithelial cells without any mesenchymal cells. The isolated cells showed an undifferentiated phenotype with scant cytoplasmic organelles, and low levels ...

journal_title：Journal of cellular physiology

authors： Hiraki A,Shirasuna K,Ikari T,Shinohara M,Garrod DR

更新日期：2002-10-01 00:00:00

abstract：:Arachidonic acid when added simultaneously with the chemotactic peptide formyl-methionyl-leucyl-phenylalanine (f-Met-Leu-Phe) inhibits the ability of the latter to initiate several but not all of its effects on rabbit peritoneal neutrophils. Stimulated neutrophil aggregation, calcium uptake, and increases in the stead...

journal_title：Journal of cellular physiology

authors： Naccache PH,Molski TF,Volpi M,Mackin WM,Becker EL,Sha'afi RI

更新日期：1983-06-01 00:00:00

abstract：:A mutant of BHK cells (ts422E) temperature-sensitive for processing 32S rRNA to 28S rRNA (Toniolo et al., '73) also loses the ability to synthesize polyamines and 5.8S rRNA when shifted to the non-permissive temperature (39 degrees). The activity of several enzymes not involved with polyamine synthesis, methylation of...

journal_title：Journal of cellular physiology

authors： Levin EG,Clark JL

更新日期：1979-12-01 00:00:00

abstract：:Optimal stimulation of signal transduction and biological functions by IGF-I in porcine smooth muscle cells (pSMC) requires ligand occupancy of the alphaVbeta3 integrin. Binding of heparin-binding domain (HBD) of vitronectin (VN) to the cysteine loop (C-loop) region of beta3 is required for pSMC to respond optimally t...

journal_title：Journal of cellular physiology

authors： Xi G,Maile LA,Yoo SE,Clemmons DR

更新日期：2008-02-01 00:00:00

abstract：:Liver regeneration involves not only hepatocyte replication but progenitor aggregation and scarring. Partial hepatectomy (PH), an established model for liver regeneration, reactivates transforming growth factor-β (TGF-β) signaling. Hepatic stellate cells (HSCs) are primarily responding cells for TGF-β and resident in ...

journal_title：Journal of cellular physiology

authors： Chen Z,Wan L,Jin X,Wang W,Li D

更新日期：2020-03-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most common malignancy in head and neck cancer and a global cause of cancer-related death. Due to the poor survival rates associated with OSCC, there is a growing need to develop novel technologies and predictive biomarkers to improve disease diagnosis. The identification of ...

journal_title：Journal of cellular physiology

authors： Wang Q,Zhi Y,Ren W,Li S,Dou Z,Xing X,Quan X,Wang Y,Jiang C,Liang X,Gao L,Zhi K

更新日期：2019-01-28 00:00:00

abstract：:The effect of hypoxia on 3T3-L1 cell differentiation was examined in confluent cultures incubated with differentiation medium (DM) followed by incubation in growth medium (GM). Control cultures remained in GM throughout the incubation period. Eight days after the incubation, cells were assessed either for changes in m...

journal_title：Journal of cellular physiology

authors： Sahai A,Patel MS,Zavosh AS,Tannen RL

更新日期：1994-07-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) is one of the critical infectious agents with thousands of newly infected people worldwide. High mutational capability and rapid diversification, inhibition of humoral and cellular immune responses, and thus inability for recognition of an immunogenic region in the viral envelope by ...

journal_title：Journal of cellular physiology

authors： Mazarzaei A,Vafaei M,Ghasemian A,Mirforughi SA,Rajabi Vardanjani H,Alwan NAS

更新日期：2019-02-18 00:00:00

abstract：:Construction of artificial organs and tissues by tissue engineering is strongly dependent on the availability of viable cells. For that reason, the viability and the physiological status of cells kept in culture must be evaluated before the cells can be used for clinical purposes. In this work, we determined the viabi...

journal_title：Journal of cellular physiology

authors： Alaminos M,Sanchez-Quevedo MC,Muñoz-Avila JI,García JM,Crespo PV,González-Andrades M,Campos A

更新日期：2007-06-01 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs) are considered as the main cell source for myelination in the central nervous system. Following demyelination, proliferation, migration, and differentiation capability of endogenous OPCs remarkably increase leading to remyelination in damaged areas. Despite the beneficial impacts...

journal_title：Journal of cellular physiology

authors： Yavarpour-Bali H,Nakhaei-Nejad M,Yazdi A,Ghasemi-Kasman M

更新日期：2020-03-01 00:00:00

abstract：:The E5 protein of the bovine papillomavirus induces cellular transformation when transfected into NIH 3T3 cells, and the extent of focal transformation is enhanced by cotransfection with the epidermal growth factor (EGF) receptor (Martin et al., Cell 59:21-32, 1989). To determine whether E5 affects EGF:receptor intera...

journal_title：Journal of cellular physiology

authors： Waters CM,Overholser KA,Sorkin A,Carpenter G

更新日期：1992-08-01 00:00:00

abstract：:Proliferation of human skin fibroblasts was stimulated significantly by the presence of L-ascorbic acid 2-phosphate (Asc 2-P). The presence of Asc 2-P (0.1-1.0 mM) in the culture medium for 3 weeks enhanced the relative rate of collagen synthesis to total protein synthesis 2-fold as well as cell growth 4-fold. Coexist...

journal_title：Journal of cellular physiology

authors： Hata R,Senoo H

更新日期：1989-01-01 00:00:00

abstract：:Activation of CD4+ T cells requires processing of exogenous protein antigens by antigen-presenting cells (APC). A macrophage hybridoma and B cell lymphoma were comparable in their ability to process hen egg lysozyme (HEL), which involves reduction of its disulfide bonds. The intracellular levels of cysteine and glutat...

journal_title：Journal of cellular physiology

authors： Gainey D,Short S,McCoy KL

更新日期：1996-08-01 00:00:00

abstract：:Over the past decade, a wide range of scientific investigations have been performed to reveal neuropathological aspects of cognitive disorders; however, only limited therapeutic approaches currently exist. The failures of conventional therapeutic options as well as the predicted dramatic rise in the prevalence of cogn...

journal_title：Journal of cellular physiology

authors： Farzaei MH,Bahramsoltani R,Abbasabadi Z,Braidy N,Nabavi SM

更新日期：2019-03-01 00:00:00

abstract：:This study examined the role of agonist-induced Rho kinase (ROCK) involvement in the morphological outcome of pulmonary-derived fibroblasts. Normal human lung fibroblasts (NHLF) spontaneously differentiate into network-like structures in a two-dimensional growth factor reduced Matrigel matrix-based assay. Sphingosine ...

journal_title：Journal of cellular physiology

authors： Harvey KA,Paranavitana CN,Zaloga GP,Siddiqui RA

更新日期：2007-05-01 00:00:00

abstract：:The components of 45calcium (Ca) uptake were studied in saponin skinned rat caudal artery. The steady-state Ca content increased when the free Ca concentration was varied from 10(-8) to 10(-4) M but was reduced by azide when the free Ca concentration exceeded 3.1 microM. The azide sensitivity and low affinity for Ca w...

journal_title：Journal of cellular physiology

authors： Stout MA

更新日期：1991-12-01 00:00:00

abstract：:Leukotriene C4 is an arachidonic acid metabolite and an important mediator of inflammation and anaphylaxis that is known to induce production of prostacyclin in endothelial cells. The goal of this study was to examine the signal transduction mechanisms activated by leukotriene C4 stimulation. Formation of inositol pho...

journal_title：Journal of cellular physiology

authors： Geirsson A,Halldórsson H,Magnúsdóttir K,Kjeld M,Thorgeirsson G

更新日期：1998-10-01 00:00:00

abstract：:The eukaryotic translation initiation factor 5A (eIF5A) contains a special amino acid residue named hypusine that is required for its activity, being produced by a post-translational modification using spermidine as substrate. Stem cells from rat skeletal muscles (satellite cells) were submitted to differentiation and...

journal_title：Journal of cellular physiology

authors： Luchessi AD,Cambiaghi TD,Hirabara SM,Lambertucci RH,Silveira LR,Baptista IL,Moriscot AS,Costa-Neto CM,Curi R

更新日期：2009-03-01 00:00:00

abstract：:Rap1 is a small GTP-binding protein (SMG) that exists in two 95% homologous isoforms, rap1A and rap1B. The functions of the rap1 proteins are not well understood. In this report we examined expression and function of rap1 in primary (HOKs) and immortalized (IHOKs) human oral keratinocytes under different growth condit...

journal_title：Journal of cellular physiology

authors： D'Silva NJ,Mitra RS,Zhang Z,Kurnit DM,Babcock CR,Polverini PJ,Carey TE

更新日期：2003-09-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor-γ coactivator-1 deficient (Pgc-1β-/- ) murine hearts model the increased, age-dependent, ventricular arrhythmic risks attributed to clinical conditions associated with mitochondrial energetic dysfunction. These were accompanied by compromised action potential (AP) upstroke ra...

journal_title：Journal of cellular physiology

authors： Ahmad S,Valli H,Smyth R,Jiang AY,Jeevaratnam K,Matthews HR,Huang CL

更新日期：2019-04-01 00:00:00

abstract：:Polyoma transformed hamster cells (PyBHK) and SV40 transformed mouse cells (SV3T3) were transferred in culture using crystalline trypsin followed by neutralisation with soybean trypsin inhibitor. Such cells were able to proliferate freely in defined medium without any serum supplement and without any intervening perio...

journal_title：Journal of cellular physiology

authors： Bush H,Shodell M

更新日期：1977-03-01 00:00:00

abstract：:The 94-kDa glucose-regulated protein (GRP94) is a glycoprotein in the endoplasmic reticulum (ER). It has been characterized as a Ca2+-binding protein and a molecular chaperone. In this report we show that highly purified GRP94 exhibits an active Mg2+-dependent serine kinase activity (termed 94-kinase). The 94-kinase c...

journal_title：Journal of cellular physiology

authors： Ramakrishnan M,Schönthal AH,Lee AS

更新日期：1997-02-01 00:00:00

abstract：:Secretion by neutrophils contributes to acute inflammation following injury or infection. Vimentin has been shown to be important for secretion by neutrophils but little is known about its dynamics during secretion, which is regulated by cyclin-dependent kinase 5 (Cdk5). In this study, we sought to examine the vimenti...

journal_title：Journal of cellular physiology

authors： Lee KY,Liu L,Jin Y,Fu SB,Rosales JL

更新日期：2012-02-01 00:00:00

abstract：:Hydatid cyst, the larval stage of the tapeworm Echinococcus granulosus and a causative agent of cystic echinococcosis, possesses a vast number of antigenic peptides that are constantly presented in the host immune system during infection. Here, we sought to provide more information about the cellular/humoral component...

journal_title：Journal of cellular physiology

authors： Vatankhah A,Ghaffari SMR,Vatankhah RG,Piurkó V,Tímár J,Avan A,Jazayeri MH

更新日期：2019-03-01 00:00:00

abstract：:Glycochenodeoxycholate (GCDA) is closely associated with carcinogenesis and chemoresistance of hepatocellular carcinoma (HCC). Signal transducer and activator of transcription 3 (STAT3), a transcription factor, is involved in various human tumors. Whether GCDA induces chemoresistance through STAT3 and the mechanism of...

journal_title：Journal of cellular physiology

authors： Wang J,Zhou M,Jin X,Li B,Wang C,Zhang Q,Liao M,Hu X,Yang M

更新日期：2020-03-01 00:00:00

abstract：:The polyamine analogue N1,N12bis(ethyl)spermine (BESpm) is a potent inhibitor of cell proliferation and is representative of a class of agents currently in clinical trials. Previous studies have demonstrated that BESpm treatment can produce a decrease in the mRNA levels of the protooncogene c-myc resulting from decrea...

journal_title：Journal of cellular physiology

authors： Berchtold CM,Tamez P,Kensler TW,Casero RA Jr

更新日期：1998-03-01 00:00:00

abstract：:Hyperthermia has long been known as a radio-sensitizing agent that displays anti-tumor effects, and has been developed as a therapeutic application. The mechanisms of hyperthermia-induced radio-sensitization are highly associated with inhibition of DNA repair. Our investigations aimed to show how hyperthermia inactiva...

journal_title：Journal of cellular physiology

authors： Genet SC,Fujii Y,Maeda J,Kaneko M,Genet MD,Miyagawa K,Kato TA

更新日期：2013-07-01 00:00:00

abstract：:A new system for studying growth of normal human mammary epithelial cells in an in vivo environment using athymic nude mice is described. Human mammary epithelial cells dissociated from reduction mammoplasty specimens were embedded within collagen gels and subsequently transplanted subcutaneously into nude mice. Histo...

journal_title：Journal of cellular physiology

authors： Popnikolov NK,Yang J,Guzman RC,Swanson SM,Thordarson G,Collins G,Talamantes F,Nandi S

更新日期：1995-04-01 00:00:00

abstract：:When calcium is removed from culture medium, motility of cultured cells is decreased. The effect is rapid, reversible and pronounced. Decreased motility is observed with normal mouse Balb/c 3T3 cells, mouse L929 cells, rat kidney fibroblasts and chick embryo fibroblasts. The calcium dependence of movement can be obser...

journal_title：Journal of cellular physiology

authors： Moore L,Pastan I

更新日期：1979-10-01 00:00:00

abstract：:The molecular weight of rat basic fibroblast growth factor is predicted to be 18 kDa when the amino acid sequence is read from the single AUG initiation codon found in the cDNA. DNA sequencing upstream of this AUG codon indicated, however, that there was an extended open reading frame. In vitro translation of the rat ...

journal_title：Journal of cellular physiology

authors： Powell PP,Klagsbrun M

更新日期：1991-08-01 00:00:00