Analysis of the influences of the E5 transforming protein on kinetic parameters of epidermal growth factor binding and metabolism.

abstract：:We evaluated the role of CCL20 (MIP-3alpha) chemokine in cells directly involved in the remodeling of bone tissue (osteoblasts and osteoclasts) and we confirmed its expression in the subchondral bone tissue of rheumatoid arthritis (RA) patients. The expression of CCL20 and of its receptor CCR6 was evaluated in osteobl...

journal_title：Journal of cellular physiology

authors： Lisignoli G,Piacentini A,Cristino S,Grassi F,Cavallo C,Cattini L,Tonnarelli B,Manferdini C,Facchini A

更新日期：2007-03-01 00:00:00

abstract：:Acupuncture needle rotation has been previously shown to cause specific mechanical stimulation of subcutaneous connective tissue. This study uses acupuncture to investigate the role of mechanotransduction-based mechanisms in mechanically-induced cytoskeletal remodeling. The effect of acupuncture needle rotation was qu...

journal_title：Journal of cellular physiology

authors： Langevin HM,Bouffard NA,Badger GJ,Churchill DL,Howe AK

更新日期：2006-06-01 00:00:00

abstract：:Polyoma transformed hamster cells (PyBHK) and SV40 transformed mouse cells (SV3T3) were transferred in culture using crystalline trypsin followed by neutralisation with soybean trypsin inhibitor. Such cells were able to proliferate freely in defined medium without any serum supplement and without any intervening perio...

journal_title：Journal of cellular physiology

authors： Bush H,Shodell M

更新日期：1977-03-01 00:00:00

abstract：:When calcium is removed from culture medium, motility of cultured cells is decreased. The effect is rapid, reversible and pronounced. Decreased motility is observed with normal mouse Balb/c 3T3 cells, mouse L929 cells, rat kidney fibroblasts and chick embryo fibroblasts. The calcium dependence of movement can be obser...

journal_title：Journal of cellular physiology

authors： Moore L,Pastan I

更新日期：1979-10-01 00:00:00

abstract：:HeLa (substrain Ho) grown in serum free medium showed an increase in the specific activity of alkaline phosphatase when fetal calf serum (10%) was added to the medium (9.7 nmoles/sec/mg protein to 86.8). Under the same conditions, eight intracellular enzymes showed no increase in activity. Similar results were obtaine...

journal_title：Journal of cellular physiology

authors： Carlson CW

更新日期：1979-01-01 00:00:00

abstract：:The F-40 cell line, a stable variant of LM fibroblasts selected for its resistance to polyethylene glycol (PEG)-induced fusion (Roos and Davidson: Somatic Cell and Molecular Genetics 6:381-391, 1980), has a decreased capacity to internalize fluid-phase markers and nonspecifically surface-bound macromolecules. It is no...

journal_title：Journal of cellular physiology

authors： Ryser HJ,Li W,Mandel R,Shen WC

更新日期：1988-12-01 00:00:00

abstract：:Pyroptosis, a type of programmed cell death mediated by gasdermin, is characterized by the swelling and rupture of cells, release of cellular contents and a strong inflammatory response, which is critical for controlling microbial infection. Pattern recognition receptors recognize the intracellular and extracellular p...

journal_title：Journal of cellular physiology

authors： Xia X,Wang X,Zheng Y,Jiang J,Hu J

更新日期：2019-06-01 00:00:00

abstract：:The cellular basis of the membrane-limited state of glucose utilization and the mechanism of the endogenous regulation of hexose uptake in dense monolayers of C6 glioma cells were investigated. In an earlier study, it was shown that at high rates of glucose transport and phosphorylation combined with the inhibition of...

journal_title：Journal of cellular physiology

authors： Lange K,Brandt U,Keller K,Zimmermann B

更新日期：1989-07-01 00:00:00

abstract：:Cancer chemotherapy can cause significant damage to the bone marrow (BM) microvascular (sinusoidal) system. Investigations must now address whether and how BM sinusoidal endothelial cells (SECs) can be protected during chemotherapy. Herein we examined the potential protective effects of genistein, a soy-derived flavon...

journal_title：Journal of cellular physiology

authors： Hassanshahi M,Su YW,Khabbazi S,Fan CM,Chen KM,Wang JF,Qian A,Howe PR,Yan DW,Zhou HD,Xian CJ

更新日期：2019-07-01 00:00:00

abstract：:Brain arteriovenous malformations (bAVM) arise as congenital or sporadic focal lesions with a significant risk for intracerebral hemorrhage (ICH). A wide range of interindividual differences is present in the onset, progression, and severity of bAVM. A growing body of gene expression and polymorphism-based research st...

journal_title：Journal of cellular physiology

authors： Krithika S,Sumi S

更新日期：2020-12-20 00:00:00

abstract：:Chronic exposure of pancreatic beta-cells to supraphysiologic glucose causes adverse beta-cell dysfunction. Thus, the present study was aimed to investigate the hypothesis that oral administration of resveratrol attenuates hyperglycemia, proinflammatory cytokines and antioxidant competence and protects beta-cell ultra...

journal_title：Journal of cellular physiology

authors： Palsamy P,Subramanian S

更新日期：2010-08-01 00:00:00

abstract：:Parkinson's disease (PD) is one of the most common movement disorders with loss of dopaminergic neurons and the presence of Lewy bodies in certain brain areas. However, it is not clear how Lewy body (inclusion with protein aggregation) formation occurs. Mutations in leucine-rich repeat kinase 2 (LRRK2) can cause a gen...

journal_title：Journal of cellular physiology

authors： Thomas JM,Wang X,Guo G,Li T,Dai B,Nucifora LG,Nucifora FC Jr,Liu Z,Xue F,Liu C,Ross CA,Smith WW

更新日期：2020-10-01 00:00:00

abstract：:Data on the biological effects of some overexpressed oncogenes and their cooperation with cellular factors are, at least partially, contradictory. There are reports on the strong pro-apoptotic action of temperature-sensitive (ts) p53(135val) in transformed cells at permissive temperature. However, in our experience ve...

journal_title：Journal of cellular physiology

authors： Schmid G,Kramer MP,Wesierska-Gadek J

更新日期：2009-05-01 00:00:00

abstract：:Rat thyroid follicles in both the normal and the inverted configuration have been cultured in suspension. It has been found that normal follicles (i.e., those having a structural organization similar to the follicles in vivo) express most functional properties of the thyroid gland. They trap iodide, synthesize, secret...

journal_title：Journal of cellular physiology

authors： Tacchetti C,Zurzolo C,Monticelli A,Nitsch L

更新日期：1986-01-01 00:00:00

abstract：:The influence upon different cellular and humoral parameters of hemopoiesis of three structurally unrelated, highly purified bacterial cell-wall components (BCWC) was investigated. The spleens of C57BL/6 mice assayed 6 days after the injection of either lipid A or outer-membrane lipoportein, but not murein, showed a m...

journal_title：Journal of cellular physiology

authors： Staber FG,Johnson GR

更新日期：1980-10-01 00:00:00

abstract：:Methionine dependence is a metabolic defect found thus far only in transformed and malignant cells. The defect is manifested as the inability of cells to grow in media in which methionine (Met) is replaced by its immediate precursor homocysteine (Hcy). We have termed this Met- Hcy+ media. We demonstrate here that meth...

journal_title：Journal of cellular physiology

authors： Stern PH,Wallace CD,Hoffman RM

更新日期：1984-04-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common malignancies and is a serious threat to people's health worldwide. The prognosis of advanced HCC is dim if left untreated. In the clinic, the treatment options for advanced HCC include surgery, radiotherapy, transcatheter arterial chemoembolization, and so forth...

journal_title：Journal of cellular physiology

authors： Zhu J,Yin T,Xu Y,Lu XJ

更新日期：2019-08-01 00:00:00

abstract：:Although the mechanism is unknown, infiltration anesthetics are believed to have membrane-stabilizing action. We report here that such a most commonly used anesthetic, lidocaine, effectively inhibited the invasive ability of human cancer (HT1080, HOS, and RPMI-7951) cells at concentrations used in surgical operations ...

journal_title：Journal of cellular physiology

authors： Mammoto T,Higashiyama S,Mukai M,Mammoto A,Ayaki M,Mashimo T,Hayashi Y,Kishi Y,Nakamura H,Akedo H

更新日期：2002-09-01 00:00:00

abstract：:Secretion by neutrophils contributes to acute inflammation following injury or infection. Vimentin has been shown to be important for secretion by neutrophils but little is known about its dynamics during secretion, which is regulated by cyclin-dependent kinase 5 (Cdk5). In this study, we sought to examine the vimenti...

journal_title：Journal of cellular physiology

authors： Lee KY,Liu L,Jin Y,Fu SB,Rosales JL

更新日期：2012-02-01 00:00:00

abstract：:Activation of the receptor tyrosine kinase c-kit by the kit-ligand, also known as stem cell factor (SCF), is essential to melanocyte and germ cell development and during the early stages of hematopoiesis. Deregulated expression of c-kit has been reported in malignancies affecting these lineages, i.e., myeloid leukemia...

journal_title：Journal of cellular physiology

authors： Bellone G,Silvestri S,Artusio E,Tibaudi D,Turletti A,Geuna M,Giachino C,Valente G,Emanuelli G,Rodeck U

更新日期：1997-07-01 00:00:00

abstract：:NEAT1 is an important tumor oncogenic gene in various tumors. Nevertheless, its involvement remains poorly studied in cervical cancer. Our study explored the functional mechanism of NEAT1 in cervical cancer. NEAT1 level in several cervical cancer cells was quantified and we found NEAT1 was greatly upregulated in vitro...

journal_title：Journal of cellular physiology

authors： Yuan LY,Zhou M,Lv H,Qin X,Zhou J,Mao X,Li X,Xu Y,Liu Y,Xing H

更新日期：2019-08-01 00:00:00

abstract：:Hemodynamic forces influence many endothelial cell functions. The coupling between hemodynamic forces and cell function could be mediated by mechano-sensitive ion channels present in the plasma membrane of endothelial cells. Because one of these channels is permeable to Ca2+, we tested whether hemodynamic forces influ...

journal_title：Journal of cellular physiology

authors： Oliver JA,Chase HS Jr

更新日期：1992-04-01 00:00:00

abstract：:The anti-apoptosis protein, survivin, promotes cell survival and mitosis. Recent studies have demonstrated that survivin is expressed in normal gastric mucosa. Using an in vitro model, we examined whether survivin plays a role in the cytoprotection produced in gastric mucosa by mild irritant ethanol (ETOH) against sub...

journal_title：Journal of cellular physiology

authors： Jones MK,Padilla OR,Webb NA,Norng M

更新日期：2008-06-01 00:00:00

abstract：:Activation of hepatic progenitor cells (HPCs) is commonly observed in chronic liver disease and Wnt/β-catenin signaling plays a crucial role in the expansion of HPCs. However, the molecular mechanisms that regulate the activation of Wnt/β-catenin signaling in the liver, especially in HPCs, remain largely elusive. Here...

journal_title：Journal of cellular physiology

authors： Ding ZY,Liang HF,Jin GN,Chen WX,Wang W,Datta PK,Zhang MZ,Zhang B,Chen XP

更新日期：2014-05-01 00:00:00

abstract：:Several organic cations are actively transported by proximal renal tubules by mediated processes across both the apical and basolateral cell membranes. In order to evaluate this transport system in a cultured renal epithelium, uptake of 3H-tetraethylammonium (TEA) across the apical membrane was measured in LLCPK1 cell...

journal_title：Journal of cellular physiology

authors： McKinney TD,DeLeon C,Speeg KV Jr

更新日期：1988-12-01 00:00:00

abstract：:The components of unidirectional K influx and efflux have been investigated in the 3T3 cell and the SV40 transformed 3T3 cell in expontntial and stationary growth phase. Over the cell densities used for transport experiments the 3T3 cell goes from exponential growth to density dependent inhibition of growth (4 X 10(4)...

journal_title：Journal of cellular physiology

authors： Spaggiare S,Wallach MJ,Tupper JT

更新日期：1976-11-01 00:00:00

abstract：:Aberrations of DNA methylation are early events in the development of tumors. In this study, we investigated the DNA methylation status of growth hormone secretagogue receptor (GHSR), a promising pan-cancer biomarker, in gastric cancer (GC). Initially, data sets from DNA methylation and gene expression studies availab...

journal_title：Journal of cellular physiology

authors： Amini M,Foroughi K,Talebi F,Aghagolzade Haji H,Kamali F,Jandaghi P,Hoheisel JD,Manoochehri M

更新日期：2019-01-24 00:00:00

abstract：:Shear stress changes are associated with a repertory of signaling cascade modulating vascular phenotype. As shear stress-related tensional forces might be associated with pathophysiological susceptibility, a more comprehensive molecular map needs to be addressed. Thus, we subjected human umbilical vein endothelial cel...

journal_title：Journal of cellular physiology

authors： Pinto TS,Fernandes CJDC,da Silva RA,Gomes AM,Vieira JCS,Padilha PM,Zambuzzi WF

更新日期：2019-07-01 00:00:00

abstract：:Osteoclasts, bone resorbing cells, derive from monocyte/macrophage cell lineage. Increased osteoclast activity is responsible for bone destruction in diseases such as osteoporosis, periodontitis and rheumatoid arthritis. Transglutaminases (TGs), protein crosslinking enzymes, were recently found involved in osteoclasto...

journal_title：Journal of cellular physiology

authors： Sun H,Kaartinen MT

更新日期：2018-09-01 00:00:00

abstract：:Type IV collagenases are secreted as latent 92 and 72 kDa proenzymes which are then activated extracellularly. The mechanisms by which they are activated in vivo are not clear. We have studied the activation of porcine endothelial cell type IV collagenases by tissue and plasma kallikrein, and found that tissue kallikr...

journal_title：Journal of cellular physiology

authors： Desrivières S,Lu H,Peyri N,Soria C,Legrand Y,Ménashi S

更新日期：1993-12-01 00:00:00