Analysis of the protein glycosylation defect of a temperature-sensitive cell cycle mutant by the use of mutant cells overexpressing the human epidermal growth factor receptor after transfection of the gene.

abstract：:Cholangiocarcinoma (CCA) is a mortal cancer with gradually increasing incidences all over the world, whereas effective diagnosis and treatment for this disease are still lacking. As a classical long noncoding RNA (lncRNA), maternally expressed gene 3 (MEG3) has been reported to exhibit pivotal regulatory roles in the ...

journal_title：Journal of cellular physiology

authors： Li J,Jiang X,Li C,Liu Y,Kang P,Zhong X,Cui Y

更新日期：2019-12-01 00:00:00

abstract：:The platelet-derived growth factor (PDGF) binds via a defined amino acid sequence to heparin (Fager et al., 1992, In Vitro Cell. Dev. Biol., 28A:176-180) and the protein moiety of low density lipoproteins (LDL; apo B-100) via a similar sequence to chondroitin sulfate (Camejo et al., 1988, Arteriosclerosis Thromb., 8:3...

journal_title：Journal of cellular physiology

authors： Fager G,Camejo G,Olsson U,Ostergren-Lundén G,Lustig F,Bondjers G

更新日期：1995-05-01 00:00:00

abstract：:In this present study, Oreochromis mossambicus tilapia were transferred to cold water at 12°C for various time intervals (1, 4, 8, 24, and 48 hr) and its innate immune response was analyzed by studying cellular and humoral parameters. In vivo, alternative complement pathway activity in blood plasma was rapidly increas...

journal_title：Journal of cellular physiology

authors： Velmurugan BK,Chan CR,Weng CF

更新日期：2019-02-11 00:00:00

abstract：:Activated hepatic stellate cells promote hepatocellular carcinoma (HCC) progression. Hepatic stellate cells play a key role in retinoid metabolism, and activation of stellate cells increases retinoic acid (RA) in the liver. However, the role of RA in HCC proliferation remains unclear. We aimed to analyse the mechanism...

journal_title：Journal of cellular physiology

authors： Lin HH,Peng YJ,Tsai MJ,Wu YY,Tsai TN,Huang HH,Shih YL,Chang WK,Hsieh TY

更新日期：2020-02-01 00:00:00

abstract：:Hydrocortisone and dexamethasone produced a time-dependent increase [125I]epidermal growth factor [( 125I]EGF) binding in primary cultures of isolated rat hepatocytes. Maximally effective doses of glucocorticoids resulted in a 70-100% increase in binding. The effect was similar when hepatocytes were maintained on coll...

journal_title：Journal of cellular physiology

authors： Lin Q,Blaisdell J,O'Keefe E,Earp HS

更新日期：1984-06-01 00:00:00

abstract：:Ack1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. It integrates signals from plethora of ligand-activated receptor tyrosine kinases (RTKs), for example, MERTK, EGFR, HER2, PDGFR and insulin receptor to initiate intra...

journal_title：Journal of cellular physiology

authors： Mahajan K,Mahajan NP

更新日期：2010-08-01 00:00:00

abstract：:Control of the terminal event in cellular differentiation is an important normal regulatory process, and the expression of defects in the control of this process has been implicated in the pathogenesis of cancer. To determine if tumor necrosis factor (TNF), which is an important biological response modifier, can inhib...

journal_title：Journal of cellular physiology

authors： Filipak M,Sparks RL,Tzen CY,Scott RE

更新日期：1988-11-01 00:00:00

abstract：:Pyroptosis, a type of programmed cell death mediated by gasdermin, is characterized by the swelling and rupture of cells, release of cellular contents and a strong inflammatory response, which is critical for controlling microbial infection. Pattern recognition receptors recognize the intracellular and extracellular p...

journal_title：Journal of cellular physiology

authors： Xia X,Wang X,Zheng Y,Jiang J,Hu J

更新日期：2019-06-01 00:00:00

abstract：:A new system for studying growth of normal human mammary epithelial cells in an in vivo environment using athymic nude mice is described. Human mammary epithelial cells dissociated from reduction mammoplasty specimens were embedded within collagen gels and subsequently transplanted subcutaneously into nude mice. Histo...

journal_title：Journal of cellular physiology

authors： Popnikolov NK,Yang J,Guzman RC,Swanson SM,Thordarson G,Collins G,Talamantes F,Nandi S

更新日期：1995-04-01 00:00:00

abstract：:Selenium has been associated with cancer prevention. Despite vast knowledge of selenium effect on various health conditions, functional characterization of selenium metabolic enzymes on cellular physiology has been limited. Therefore, to gain insight into the mechanisms underlying cancer prevention by selenium, we inv...

journal_title：Journal of cellular physiology

authors： Chung HJ,Yoon SI,Shin SH,Koh YA,Lee SJ,Lee YS,Bae S

更新日期：2006-10-01 00:00:00

abstract：:Human neutrophils labeled with chlortetracycline (CTC), commonly used as a probe of membrane-bound calcium, release lysosomal enzymes and exhibit a rapid decrease in fluorescence when exposed to the chemotactic peptide fMet-Leu-Phe or the lectin Con A. This decrease has been attributed to the release of calcium from a...

journal_title：Journal of cellular physiology

authors： Smolen JE,Noble P,Freed R,Weissmann G

更新日期：1983-12-01 00:00:00

abstract：:BP3T3, a clonal benzo(a)pyrene-transformed BALB/c-3T3 cell line, is conditionally responsive to growth factor stimulation. Density arrested cell populations deprived of growth factors by pretreatment with 0.5% platelet-poor plasma synthesized DNA both in response to ng/ml concentrations of PDGF, EGF, and somatomedin C...

journal_title：Journal of cellular physiology

authors： Whipple AP,Furlanetto RW,Scher CD

更新日期：1987-02-01 00:00:00

abstract：:The tumor-promoting phorbol ester, 12-0-tetradecanoyl-phorbol-13-acetate (TPA), stimulates starch-elicited mouse peritoneal macrophages to undergo DNA synthesis in vitro, apparently without the generation of an endogenous macrophage growth factor (MGF). No evidence was found for any synergistic interaction between TPA...

journal_title：Journal of cellular physiology

authors： Hamilton JA

更新日期：1983-04-01 00:00:00

abstract：:Chronic hyperglycemia and activation of receptor for advanced glycation end products (RAGE) are known risk factors for microvascular disease development in diabetic retinopathy. Thioredoxin-interacting protein (TXNIP), an endogenous inhibitor of antioxidant thioredoxin (TRX), plays a causative role in diabetes and its...

journal_title：Journal of cellular physiology

authors： Perrone L,Devi TS,Hosoya K,Terasaki T,Singh LP

更新日期：2009-10-01 00:00:00

abstract：:Melatonin, the major pineal secretory product, has a significant impact on the female reproductive system. Recently, the beneficial effects of melatonin on mammalian oocyte maturation and embryonic development have drawn increased attention. However, the exact underlying mechanisms remain to be fully elucidated. This ...

journal_title：Journal of cellular physiology

authors： He B,Yin C,Gong Y,Liu J,Guo H,Zhao R

更新日期：2018-01-01 00:00:00

abstract：:The differentiation of mesenchymal stem cells (MSCs) into type II alveolar epithelial (AT II) cells in vivo and in vitro, is critical for reepithelization and recovery in acute lung injury (ALI), but the mechanisms responsible for differentiation are unclear. In the present study, we investigated the role of the canon...

journal_title：Journal of cellular physiology

authors： Liu AR,Liu L,Chen S,Yang Y,Zhao HJ,Liu L,Guo FM,Lu XM,Qiu HB

更新日期：2013-06-01 00:00:00

abstract：:Lithium has been used or explored to treat psychiatric and neurodegenerative diseases that are frequently associated with an abnormal immune status. It is likely that lithium may work through modulation of immune responses in these patients. Because dendritic cells (DC) play a central role in regulating immune respons...

journal_title：Journal of cellular physiology

authors： Liu KJ,Lee YL,Yang YY,Shih NY,Ho CC,Wu YC,Huang TS,Huang MC,Liu HC,Shen WW,Leu SJ

更新日期：2011-02-01 00:00:00

abstract：:The Toll and Toll-like receptor signaling pathways are evolutionarily conserved pathways that regulate innate immunity in insects and mammals. While efforts have been made to clarify the signal transduction events that occur during infection, much less is known about the components that maintain immune quiescence. Her...

journal_title：Journal of cellular physiology

authors： Zhou B,Yun EY,Ray L,You J,Ip YT,Lin X

更新日期：2014-04-01 00:00:00

abstract：:Simian Virus 40 (SV40), a monkey polyomavirus, was administered to human populations by early anti-poliomylitis vaccines contaminated by this small DNA tumor virus. Data on SV40 infection in humans remain controversial. Elderly subjects represent an interesting cohort to investigate, because they were not immunized wi...

journal_title：Journal of cellular physiology

authors： Mazzoni E,Guerra G,Casali MV,Pietrobon S,Bononi I,Puozzo A,Tagliapietra A,Nocini PF,Tognon M,Martini F

更新日期：2017-01-01 00:00:00

abstract：:Biosensors are composed of (bio)receptors, transducers, and detection systems and are able to convert the biological stimulus into a measurable signal. This systematic review evaluates the current state of the art of innovation and research in this field, identifying the biosensors that in vitro monitor the musculoske...

journal_title：Journal of cellular physiology

authors： Veronesi F,Tschon M,Visani A,Fini M

更新日期：2019-12-01 00:00:00

abstract：:Using a recently described technique of electron spin resonance spectroscopy, we determined the rate of transbilayer mobility (flip) of the four major simian-erythrocyte phospholipids in the erythrocyte membrane after infection by Plasmodium knowlesi. The development of the malarial parasite induces a very large incre...

journal_title：Journal of cellular physiology

authors： Beaumelle BD,Vial HJ,Bienvenüe A

更新日期：1988-04-01 00:00:00

abstract：:Alkaptonuria (AKU) is an ultra-rare genetic disease, in which the accumulation of a toxic metabolite, homogentisic acid (HGA) leads to the systemic development of ochronotic aggregates. These aggregates cause severe complications mainly at the level of joints with extensive degradation of the articular cartilage. Prim...

journal_title：Journal of cellular physiology

authors： Gambassi S,Geminiani M,Thorpe SD,Bernardini G,Millucci L,Braconi D,Orlandini M,Thompson CL,Petricci E,Manetti F,Taddei M,Knight MM,Santucci A

更新日期：2017-11-01 00:00:00

abstract：:Previously, serum miR-188-5p is differentially expressed in breast cancer, but the diagnostic potential of circulating miR-188-5p as well as its regulatory mechanism in breast cancer remain uncertain. Herein, serum miR-188-5p was detected by real-time polymerase chain reaction in patients with breast cancer, breast fi...

journal_title：Journal of cellular physiology

authors： Wang M,Zhang H,Yang F,Qiu R,Zhao X,Gong Z,Yu W,Zhou B,Shen B,Zhu W

更新日期：2020-05-01 00:00:00

abstract：:Baculoviral IAP repeat containing 5 (BIRC5) gene encodes the important protein as survivin, a multifunctional protein, which is involved in cellular and molecular networks, progression of cell cycle, homeostasis, developmental morphogenesis, and apoptosis. The proximal BIRC5 promoter possesses specific binding sites f...

journal_title：Journal of cellular physiology

authors： Pahlavan Y,Kahroba H,Samadi N,Karimi A,Ansarin K,Khabbazi A

更新日期：2019-11-01 00:00:00

abstract：:The addition of anti-laminin IgG to the basal surfaces of rat Sertoli cells in culture in a two-chambered assembly results in a perturbation of F-actin arrangements, including disruption of the pericellular circumferal rings, impairments of the Sertoli cell permeability barrier, and subsequently focal defoliation, fol...

journal_title：Journal of cellular physiology

authors： Tung PS,Fritz IB

更新日期：1993-07-01 00:00:00

abstract：:This study is performed to examine the impacts of microRNA-218 (miR-218) on cardiac microvascular endothelial cells (CMECs) injury induced by coronary artery disease (CAD). Reverse-transcription quantitative polymerase chain reaction (RT-qPCR) was applied for detecting miR-218 expression in serum of patients with CAD ...

journal_title：Journal of cellular physiology

authors： Gao W,Cui H,Li Q,Zhong H,Yu J,Li P,He X

更新日期：2020-03-01 00:00:00

abstract：:Estrogen has been shown to protect osteoblastic cells from apoptosis. Similarly, estrogen treatment preceding heat shock elevates heat shock protein 27 (hsp27) expression and increases thermoresistance in the murine estrogen receptor-transformed SMER14 osteoblastic cell line. Forced expression of hsp27 expression in o...

journal_title：Journal of cellular physiology

authors： Cooper LF,Tiffee JC,Griffin JP,Hamano H,Guo Z

更新日期：2000-12-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha) is a pleiotropic cytokine produced by activated macrophages. IL-6 is a multifunctional cytokine that plays a central role in both innate and acquired immune responses. We investigated the signaling pathway involved in IL-6 production stimulated by TNF-alpha in cultured myoblasts...

journal_title：Journal of cellular physiology

authors： Tseng WP,Su CM,Tang CH

更新日期：2010-05-01 00:00:00

abstract：:Acute lung injury (ALI) is a severe acute inflammatory reaction of the lungs caused by a variety of factors, which can lead to a high mortality rate. MicroRNAs are a novel therapeutic molecule that play a vital role in many diseases. However, its mechanism of action in lipopolysaccharide (LPS)-induced mouse ALI is not...

journal_title：Journal of cellular physiology

authors： Guo S,Chen Y,Liu J,Yang J,Yang C,Zhang T,Jiang K,Wu Z,Shaukat A,Deng G

更新日期：2019-12-01 00:00:00

abstract：:We have characterized the physiological and biochemical properties of the Na(+)/K(+) pump and its molecular expression in L8 rat muscle cells. Pump properties were measured by [(3)H]ouabain binding and (86)Rb uptake. Scatchard plot analysis of specific ouabain binding indicated the presence of a single family of bindi...

journal_title：Journal of cellular physiology

authors： Sharabani-Yosef O,Bak A,Nir U,Sampson SR

更新日期：2001-06-01 00:00:00