Melatonin-induced increase of lipid droplets accumulation and in vitro maturation in porcine oocytes is mediated by mitochondrial quiescence.

abstract：:The interaction between dietary lectins, especially wheat germ agglutinin (WGA), and intestinal cells has been implicated in the pathogenesis of celiac disease. The present study was undertaken to investigate the immediate effects following such an interaction. Direct WGA-stimulation of Intestine 407 cells leads to an...

journal_title：Journal of cellular physiology

authors： Sjölander A

更新日期：1988-03-01 00:00:00

abstract：:In previous studies on HeLa cells we demonstrated estrogen-responsiveness of the epidermal growth factor receptor (EGFR) gene, as 17beta-estradiol (E(2)) and selective estrogen receptor modulators (SERMs) genistein (G), daidzein (D), and 4-hydroxytamoxifen (4OH-T) modulated its transcription in a ligand- and estrogen ...

journal_title：Journal of cellular physiology

authors： Salvatori L,Caporuscio F,Coroniti G,Starace G,Frati L,Russo MA,Petrangeli E

更新日期：2009-07-01 00:00:00

abstract：:The effects of adenosine and two analogs, L-phenylisopropyladenosine (L-PIA) and 5'-N-ethylcarboxamidoadenosine (NECA), on cAMP production and on platelet-derived growth factor (PDGF)-stimulated initiation of DNA synthesis in growth-arrested cultures of rat arterial smooth muscle cells (SMC) were studied. The intracel...

journal_title：Journal of cellular physiology

authors： Jonzon B,Nilsson J,Fredholm BB

更新日期：1985-09-01 00:00:00

abstract：:Inhibition of insulin-induced 3T3-L1 preadipocyte differentiation by rapamycin has been attributed to a blockade of the early critical clonal expansion phase of the adipogenic program. Rapamycin binds to, and inhibits, mTOR (mammalian target of rapamycin), leading to diminution of p70 S6 kinase activity and eukaryotic...

journal_title：Journal of cellular physiology

authors： Gagnon A,Lau S,Sorisky A

更新日期：2001-10-01 00:00:00

abstract：:Lymphocytes depleted of ATP by incubation in iodoacetate (IAA) and nitrogen (N2) lost K and gained Na. Isotopic Na exchange showed a fast fraction and a slower exponential fraction, the latter conventionally assumed to reflect surface membrane properties. The gain of cell Na was not accounted for by a decrease in 22Na...

journal_title：Journal of cellular physiology

authors： Negendank W,Shaller C

更新日期：1982-03-01 00:00:00

abstract：:Arsenicosis induced by chronic exposure to arsenic is recognized as one of the main damaging effects on public health. Exposure to arsenic can cause hepatic fibrosis, but the molecular mechanisms by which this occurs are complex and elusive. It is not known if miRNAs are involved in arsenic-induced liver fibrosis. We ...

journal_title：Journal of cellular physiology

authors： Xue J,Xiao T,Wei S,Sun J,Zou Z,Shi M,Sun Q,Dai X,Wu L,Li J,Xia H,Tang H,Zhang A,Liu Q

更新日期：2021-01-22 00:00:00

abstract：:Cultures of HeLa cells, strains S3G (HeLa65) and S3K (HeLa71) were grown in plastic dishes until firmly attached and were then treated with sonic dispersions of Rosenthal's phospholipase inhibitor. A rapid increase in alkaline phosphatase activity occurred following this treatment in the S3G strain (low inducible alka...

journal_title：Journal of cellular physiology

authors： Melnykovych G,Lopez IC

更新日期：1977-07-01 00:00:00

abstract：:To study the role of noncollagenous proteins in bone formation, the synthesis and tissue distribution of BSP (bone sialoprotein), OPN (osteopontin) and SPARC (secreted protein acidic and rich in cysteine) were analyzed using pulse-chase and continuous labeling protocols during bone formation by cultures of rat calvari...

journal_title：Journal of cellular physiology

authors： Kasugai S,Nagata T,Sodek J

更新日期：1992-09-01 00:00:00

abstract：:The role of cyclic adenosine monophosphate (cAMP) is poorly understood in the regulation of normal and abnormal hepatic cell growth. In this study, we examined the regulation of intracellular cAMP levels and its effect on nuclear cAMP responsive elements (CREs) in a rat model of hepatocellular carcinoma (HCC). Tumorig...

journal_title：Journal of cellular physiology

authors： Kovach SJ,Price JA,Shaw CM,Theodorakis NG,McKillop IH

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Elevated microsatellite alteration at selected tetranucleotide repeats (EMAST) is a type of microsatellite instability that occurs in ∼60% of colorectal cancers (CRCs) and associated with MSH3 dysfunction. A 5-fluorouracil (5-FU)-related cytotoxicity is attenuated in MSH3-deficient colon cancer cells. Report...

journal_title：Journal of cellular physiology

authors： Mohammadpour S,Goodarzi HR,Jafarinia M,Porhoseingholi MA,Nazemalhosseini-Mojarad E

更新日期：2020-04-01 00:00:00

abstract：:We previously showed that fluid flow, which chondrocytes experience in vivo and which results in a variety of morphological and metabolic changes in cultured articular chondrocytes, can also stimulate a rise in intracellular calcium concentration ([Ca2+]i). However, the mechanism by which Ca2+ is mobilized in response...

journal_title：Journal of cellular physiology

authors： Yellowley CE,Jacobs CR,Donahue HJ

更新日期：1999-09-01 00:00:00

abstract：:Ack1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. It integrates signals from plethora of ligand-activated receptor tyrosine kinases (RTKs), for example, MERTK, EGFR, HER2, PDGFR and insulin receptor to initiate intra...

journal_title：Journal of cellular physiology

authors： Mahajan K,Mahajan NP

更新日期：2010-08-01 00:00:00

abstract：:Polyoma transformed hamster cells (PyBHK) and SV40 transformed mouse cells (SV3T3) were transferred in culture using crystalline trypsin followed by neutralisation with soybean trypsin inhibitor. Such cells were able to proliferate freely in defined medium without any serum supplement and without any intervening perio...

journal_title：Journal of cellular physiology

authors： Bush H,Shodell M

更新日期：1977-03-01 00:00:00

abstract：:Members of the transforming growth factor-β (TGF-β) family of cytokines are involved in diverse physiological processes. Although TGF-β is known to play multiple roles in the mammalian central nervous system (CNS), its role in neuronal development has not been explored. We have studied the effects of TGF-β1 on the ele...

journal_title：Journal of cellular physiology

authors： Zhuang JL,Wang CY,Zhou MH,Duan KZ,Mei YA

更新日期：2012-01-01 00:00:00

abstract：:Diabetic nephropathy (DN) is one of the most serious and dangerous chronic complications caused by diabetes mellitus, and the identification and development of novel biomarkers could be beneficial for the diagnosis and prognosis of DN patients. This study focused on researching the differently expressed pattern of the...

journal_title：Journal of cellular physiology

authors： Song X,Gong M,Chen Y,Liu H,Zhang J

更新日期：2019-02-01 00:00:00

abstract：:Arachidonic acid when added simultaneously with the chemotactic peptide formyl-methionyl-leucyl-phenylalanine (f-Met-Leu-Phe) inhibits the ability of the latter to initiate several but not all of its effects on rabbit peritoneal neutrophils. Stimulated neutrophil aggregation, calcium uptake, and increases in the stead...

journal_title：Journal of cellular physiology

authors： Naccache PH,Molski TF,Volpi M,Mackin WM,Becker EL,Sha'afi RI

更新日期：1983-06-01 00:00:00

abstract：:Matrix metalloproteinase-2 (MMP-2) is best understood for its biological actions outside the cell. However, MMP-2 also localizes to intracellular compartments and the cytosol where it has several substrates, including troponin I (TnI). Despite a growing list of cytosolic substrates, we currently do not know the mechan...

journal_title：Journal of cellular physiology

authors： Ali MA,Chow AK,Kandasamy AD,Fan X,West LJ,Crawford BD,Simmen T,Schulz R

更新日期：2012-10-01 00:00:00

abstract：:Electrophysiologic properties of cultured human keratinocytes were studied using the patch voltage-clamp technique. Undifferentiated, proliferative keratinocytes grown in low Ca2+ medium had an average resting membrane potential of -24 mV. Voltage-clamp experiments showed that these cells had two membrane ionic curren...

journal_title：Journal of cellular physiology

authors： Mauro TM,Pappone PA,Isseroff RR

更新日期：1990-04-01 00:00:00

abstract：:It is presently unclear what role elevations in intracellular calcium concentration ([Ca2+]i) play in the control of monokine secretion, or whether such alterations underlie the ability of physiologic stimuli to induce production of these important signalling molecules. To address these issues, we have performed exper...

journal_title：Journal of cellular physiology

authors： Marriott I,Bost KL,Mason MJ

更新日期：1998-11-01 00:00:00

abstract：:Cancer stem cells (CSCs), also called Tumor Initiating Cells (TICs), can be defined as cancer cells that are present within solid tumors or hematological cancers, which have characteristics associated with normal stem cells, but which can give rise to all cell types found in a particular cancer sample. CSCs, therefore...

journal_title：Journal of cellular physiology

authors： Brinckerhoff CE

更新日期：2017-10-01 00:00:00

abstract：:Oral administration of ajulemic acid (AjA), a cannabinoid acid devoid of psychoactivity, prevents joint tissue injury in rats with adjuvant induced arthritis. Because activation of osteoclasts is central to the pathogenesis of bone erosion in patients with rheumatoid arthritis (RA), we investigated the influence of Aj...

journal_title：Journal of cellular physiology

authors： George KL,Saltman LH,Stein GS,Lian JB,Zurier RB

更新日期：2008-03-01 00:00:00

abstract：:Balb/C3T3 cells entered the quiescent Go state following serum deprivation. On addition of fresh serum, more than 95% of the culture resumed growth, but with asynchronous kinetics. If hydroxyurea were added just before the first cells reached S phase, at at least 90% of the cells accumulated at the Gl/S border over th...

journal_title：Journal of cellular physiology

authors： Dooley DC,Ozer HL

更新日期：1977-02-01 00:00:00

abstract：:Several proteases and their specific inhibitors modulate the interdependent processes of cell migration and matrix proteolysis as part of the global program of trauma repair. Expression of plasminogen activator inhibitor type-1 (PAI-1), a serine protease inhibitor (SERPIN) important in the control of barrier proteolys...

journal_title：Journal of cellular physiology

authors： Providence KM,Higgins PJ

更新日期：2004-08-01 00:00:00

abstract：:Glutamine is the most abundant free amino acid in the body and is known to play a regulatory role in several cell specific processes including metabolism (e.g., oxidative fuel, gluconeogenic precursor, and lipogenic precursor), cell integrity (apoptosis, cell proliferation), protein synthesis, and degradation, contrac...

journal_title：Journal of cellular physiology

authors： Curi R,Lagranha CJ,Doi SQ,Sellitti DF,Procopio J,Pithon-Curi TC,Corless M,Newsholme P

更新日期：2005-08-01 00:00:00

abstract：:Polyploidy has been linked to tumorigenicity mainly due to the chromosomal aberrations. Elevated reactive oxygen species (ROS) generation, on the other hand, has also been associated with oncogenic transformation in most cancer cells. However, a possible link between ploidy and ROS is largely unexplored. Here we have ...

journal_title：Journal of cellular physiology

authors： Roh M,van der Meer R,Abdulkadir SA

更新日期：2012-02-01 00:00:00

abstract：:Hepatic expression of the protooncogenes c-fos and c-myc occurs within 2 h after partial hepatectomy, and these immediate early genes are thought to prime the hepatocytes for subsequent proliferation. To examine whether such gene activation occurred in the setting of hepatocyte proliferation after toxic liver injury, ...

journal_title：Journal of cellular physiology

authors： Schmiedeberg P,Biempica L,Czaja MJ

更新日期：1993-02-01 00:00:00

abstract：:Several papers report a hypoxia-induced upregulation of the endothelial nitric oxide synthase (eNOS) mRNA expression. Since there is no known hypoxia-sensitive element binding site in the eNOS promoter, we reasoned that the effect of hypoxia could be simulated by a metabolically elicited alteration of the redox state....

journal_title：Journal of cellular physiology

authors： Hoffmann A,Gloe T,Pohl U

更新日期：2001-07-01 00:00:00

abstract：:The effect of cell culture age and concomitant changes in cell density on the biosynthesis of sulfated-proteoglycan by rabbit articular chondrocytes in secondary monolayer culture was studied. Low density (LD, 2 d), middle density (MD, 5-7 d), and high density (HD, 12-15 d) cultures demonstrated changes in cellular mo...

journal_title：Journal of cellular physiology

authors： Malemud CJ,Papay RS

更新日期：1984-12-01 00:00:00

abstract：:Insulin was employed as a stimulant in our continuing investigations of the molecular mechanisms involved in the coordinate control of cellular metabolism and growth. Incubation of chicken embryo fibroblasts for 16 hours in media containing 0-0.1 U insulin/ml resulted in a 17-fold increase in the rate of 3H-thymidine ...

journal_title：Journal of cellular physiology

authors： Sanui H,Rubin AH

更新日期：1978-09-01 00:00:00

abstract：:Nucleoside transporter proteins are specialized proteins that mediate the transport of nucleosides and nucleoside analog drugs across the plasma membrane. The human equilibrative nucleoside transporter 1 (hENT1) is a member of these proteins and mediates cellular entry of gemcitabine, cytarabine, and fludarabine. The ...

journal_title：Journal of cellular physiology

authors： Santini D,Vincenzi B,Fratto ME,Perrone G,Lai R,Catalano V,Cass C,Ruffini PA,Spoto C,Muretto P,Rizzo S,Muda AO,Mackey JR,Russo A,Tonini G,Graziano F

更新日期：2010-05-01 00:00:00