Microbial transformation of macrocyclic trichothecenes.

Abstract:

:A resting culture of Rhizopus arrhizus (ATCC 11145) transformed verrucarin A into 16-hydroxyverrucarin A, whereas R. arrhizus transformed verrucarin B into a mixture of 16-hydroxyverrucarin B and 3'-hydroxyverrucarin A. Relative to verrucarins A and B, the 16-hydroxy derivatives showed marked increases in activity, as tested in vivo against P388 mouse leukemia.

journal_name

Appl Environ Microbiol

authors

Pavanasasivam G,Jarvis BB

doi

10.1128/AEM.46.2.480-483.1983

keywords:

subject

Has Abstract

pub_date

1983-08-01 00:00:00

pages

480-3

issue

2

eissn

0099-2240

issn

1098-5336

journal_volume

46

pub_type

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