Potential pitfalls in diagnostic oral pathology: a review for the general surgical pathologist.

abstract：:Myoepithelial neoplasms represent a heterogeneous group of tumors of which classification is incomplete and evolving. Those of the soft tissues often form genetically distinct subgroups that differ from those arising within salivary glands. Soft-tissue myoepithelial tumors (including mixed tumors that show true glandu...

journal_title：Advances in anatomic pathology

authors： Thway K,Fisher C

更新日期：2014-11-01 00:00:00

abstract：:Approximately 25% of patients with stage I (node negative) breast cancer relapse at a rate similar to those with stage II disease. Inadvertent pathologic "understaging" of lymph node status is one plausible explanation for this phenomenon. While many studies have shown that additional sectioning +/- immunohistochemica...

journal_title：Advances in anatomic pathology

authors： Mies C,Schlesselman JJ

更新日期：2000-05-01 00:00:00

abstract：:Intraoperative consultation remains an invaluable tool in the initial evaluation of surgically excised specimens. Good communication is required between the pathologist and surgeon to obtain the best care for their mutual patient. Intraoperative consultation (frozen section, FS) provides a preliminary diagnosis for th...

journal_title：Advances in anatomic pathology

authors： Somerset HL,Kleinschmidt-DeMasters BK

更新日期：2011-11-01 00:00:00

abstract：:Anal squamous cell carcinoma and its precursor lesions are increasing in incidence in the United States and Europe. This trend predates human immunodeficiency virus/acquired immune deficiency syndrome and has been associated with persistent high-risk human papilloma virus (HPV) genotype infection, previous lower genit...

journal_title：Advances in anatomic pathology

authors： Longacre TA,Kong CS,Welton ML

更新日期：2008-09-01 00:00:00

abstract：:Endometriosis is a relatively common condition in which endometrial tissue is established in locations outside the uterus where, like the eutopic endometrium, it responds to hormonal stimuli and develops internal bleeding, inflammation, and fibrosis. These changes are associated with chronic and often debilitating cyc...

journal_title：Advances in anatomic pathology

authors： Arafah M,Rashid S,Akhtar M

更新日期：2021-01-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a broad term that includes liver diseases characterized by abnormal hepatocellular accumulations of lipid that cannot be related to alcohol abuse. It may be found in both adults and children, particularly those who are obese or have insulin resistance. Steatohepatitis is a ...

journal_title：Advances in anatomic pathology

authors： Aly FZ,Kleiner DE

更新日期：2011-07-01 00:00:00

abstract：:Paratesticular mesotheliomas are rare tumors with 223 cases described so far. The sole plausible causative factor so far ascertained in the pathogenesis of these tumors is asbestos, which however is found in only around 30% to 40% of such cases. The age range of affected individuals is wide, mostly adults and the elde...

journal_title：Advances in anatomic pathology

authors： Bisceglia M,Dor DB,Carosi I,Vairo M,Pasquinelli G

更新日期：2010-01-01 00:00:00

abstract：:Pancreatic cancer is an aggressive disease with a dismal prognosis in dire need of novel diagnostic and therapeutic approaches. The past decade has witnessed an explosion of data on the genetic alterations that occur in pancreatic cancer, as comprehensive next-generation sequencing analyses have been performed on samp...

journal_title：Advances in anatomic pathology

authors： Felsenstein M,Hruban RH,Wood LD

更新日期：2018-03-01 00:00:00

abstract：:IMP3 is a member of a family of RNA-binding proteins that consists of IMP1, IMP2 and IMP3. These proteins contain 2 RNA recognition motifs and 4 K-homology domains that allow them to bind RNAs strongly and specifically. IMP3 is an oncofetal protein involved in embryogenesis and its expression is associated with a numb...

journal_title：Advances in anatomic pathology

authors： Gong Y,Woda BA,Jiang Z

更新日期：2014-05-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is the most common form of kidney cancer in adults. RCC is a significant challenge for pathologic diagnosis and clinical management. The primary approach to diagnosis is by light microscopy, using the World Health Organization (WHO) classification system, which defines histopathologic tumor ...

journal_title：Advances in anatomic pathology

authors： Young AN,Master VA,Paner GP,Wang MD,Amin MB

更新日期：2008-01-01 00:00:00

abstract：:Nasopharyngeal angiofibromas (NA) are rare tumor-like lesions characterized by architecturally irregular vessels set in a fibrous stroma. The unique morphology, the strong predilection for male adolescents, and the uncertainty about its etiology contributes to significant confusion regarding the classification of NA, ...

journal_title：Advances in anatomic pathology

authors： Beham A,Beham-Schmid C,Regauer S,Auböck L,Stammberger H

更新日期：2000-01-01 00:00:00

abstract：:Fluorescence in-situ hybridization (FISH) has arisen as a novel ancillary test for the pathological diagnosis of melanoma. It is an outgrowth of studies using comparative genomic hybridization, a technique capable of surveying the entire genome for DNA copy number changes. An original report published in 2009 showed h...

journal_title：Advances in anatomic pathology

authors： Song J,Mooi WJ,Petronic-Rosic V,Shea CR,Stricker T,Krausz T

更新日期：2011-05-01 00:00:00

abstract：:Thyroid microcarcinoma, defined as a thyroid tumor measuring 1 cm or less, is an extremely indolent tumor. Papillary microcarcinoma, the most common subtype, is often identified incidentally in a thyroid removed for benign clinical nodules or diffuse processes (eg, thyroiditis). In this clinical situation, over 99% ar...

journal_title：Advances in anatomic pathology

authors： Baloch ZW,LiVolsi VA

更新日期：2006-03-01 00:00:00

abstract：:The topic of hereditary gynecologic malignancies readily evokes associations between Lynch syndrome and endometrial adenocarcinoma, or between BRCA mutations and tubo-ovarian serous carcinoma, but other familial associations are less well-known. Two hereditary syndromes are known to be related to uterine mesenchymal t...

journal_title：Advances in anatomic pathology

authors： Joehlin-Price AS,Garg K

更新日期：2018-03-01 00:00:00

abstract：:This review focuses on discussing the main modifications of the recently published 2017 WHO Classification of Neoplasms of the Neuroendocrine Pancreas (panNEN). Recent updates separate pancreatic neuroendocrine tumors into 2 broad categories: well-differentiated pancreatic neuroendocrine tumors (panNET) and poorly dif...

journal_title：Advances in anatomic pathology

authors： Guilmette JM,Nosé V

更新日期：2019-01-01 00:00:00

abstract：:As genomic characterization becomes increasingly necessary for accurate diagnosis of tumors of the central nervous system, identification of rapidly assessible biomarkers is equally important to avoid excessive cost and delay in initiation of therapy. This article reviews novel immunohistochemical markers that may be ...

journal_title：Advances in anatomic pathology

authors： Meredith DM

更新日期：2020-05-01 00:00:00

abstract：:Ewing Sarcoma is a developmental tumor characterized by balanced chromosomal translocations and formation of new fusion genes, which are the main hallmark of this rare entity. Despite the vast knowledge regarding the molecular aspects of this rare malignancy obtained in the last few years, including the discovery of n...

journal_title：Advances in anatomic pathology

authors： Amaral AT,Ordóñez JL,Otero-Motta AP,García-Domínguez DJ,Sevillano MV,de Álava E

更新日期：2014-01-01 00:00:00

abstract：:The main purpose of urine cytology is to detect high-grade urothelial carcinoma. With this principle in mind, The Paris System (TPS) Working Group, composed of cytopathologists, surgical pathologists, and urologists, has proposed and published a standardized reporting system that includes specific diagnostic categorie...

journal_title：Advances in anatomic pathology

authors： Barkan GA,Wojcik EM,Nayar R,Savic-Prince S,Quek ML,Kurtycz DF,Rosenthal DL

更新日期：2016-07-01 00:00:00

abstract：:The common sources of ionizing radiation exposure to the thyroid gland in humans are accidental environmental exposure and medical, therapeutic, or diagnostic irradiation. Radiation often induces notable histologic changes in the thyroid tissue and is a well-established risk factor for benign and malignant thyroid tum...

journal_title：Advances in anatomic pathology

authors： Nikiforov YE,Gnepp DR

更新日期：1999-03-01 00:00:00

abstract：:This manuscript reviews carcinomas of the upper aerodigestive tract associated with genetic rearrangements of the nuclear protein of the testis (NUT) gene, also known as NUT midline carcinomas. The literature is reviewed regarding all reported cases of NUT midline carcinomas and the clinicopathologic features are disc...

journal_title：Advances in anatomic pathology

authors： Stelow EB,French CA

更新日期：2009-03-01 00:00:00

abstract：:Epithelioid hemangioendothelioma is a vascular tumor of low to intermediate malignancy that was initially described in the soft tissue. Since then, epithelioid hemangioendothelioma has been described in various anatomic sites including parenchymal tissues and the bone. In the bone, these tumors must not only be distin...

journal_title：Advances in anatomic pathology

authors： Weissferdt A,Moran CA

更新日期：2014-07-01 00:00:00

abstract：:The development of small-molecule inhibitors of the epidermal growth factor receptor (EGFR) resulted in new therapeutic options for patients with advanced lung cancer. It was clear from the experience with targeted therapy for breast cancer that a new standardized assay procedure for assessing and predicting the effec...

journal_title：Advances in anatomic pathology

authors： Dacic S

更新日期：2008-07-01 00:00:00

abstract：:Inflammatory skin diseases encompass a vast array of conditions. The field continues to expand and evolve with resurgence of conditions, through newly recognized medication adverse effects, and via more detailed descriptions of known dermatoses. The importance of clinicopathologic correlation and an up to date knowled...

journal_title：Advances in anatomic pathology

authors： Penn L,Rothman L,Sutton AM,Brinster NK,Vidal CI

更新日期：2019-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) has distinct morphologic features and can be identified in the majority of cases by routine hematoxylin and eosin (H&E)-stained formalin-fixed paraffin-embedded sections. However, distinguishing a well-differentiated HCC from normal or regenerative tissue may be very difficult in some ca...

journal_title：Advances in anatomic pathology

authors： Varma V,Cohen C

更新日期：2004-09-01 00:00:00

abstract：:Gliomas are a large and diverse group of primary brain tumors that include those that are diffusely infiltrative and others that are well-circumscribed and low grade. Diffuse gliomas are currently classified by the World Health Organization as astrocytomas, oligodendrogliomas, or oligoastrocytomas and range in grade f...

journal_title：Advances in anatomic pathology

authors： Appin CL,Brat DJ

更新日期：2015-01-01 00:00:00

abstract：:The concept of Waldenstrom macroglobulinemia has evolved from the original description of a clinical syndrome to its more recent designation as a distinct clinicopathologic entity, that is, lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia (LPL/WM), in the World Health Organization (WHO) classification and by t...

journal_title：Advances in anatomic pathology

authors： Lin P,Medeiros LJ

更新日期：2005-09-01 00:00:00

abstract：:Tissue microarrays (TMAs) provide unique resources for rapid evaluation and validation of tissue biomarkers. The Canary Foundation Retrospective Prostate Tissue Microarray Resource used a rigorous statistical design, quota sampling, a variation of the case-cohort study, to select patients for inclusion in a multicente...

journal_title：Advances in anatomic pathology

authors： Hawley S,Fazli L,McKenney JK,Simko J,Troyer D,Nicolas M,Newcomb LF,Cowan JE,Crouch L,Ferrari M,Hernandez J,Hurtado-Coll A,Kuchinsky K,Liew J,Mendez-Meza R,Smith E,Tenggara I,Zhang X,Carroll PR,Chan JM,Gleave M,L

更新日期：2013-01-01 00:00:00

abstract：:Benign cartilaginous tumors of bones, intrinsic to their name, are tumors forming cartilaginous matrix with a clinically benign behavior. In this group, we recognize osteochondromas, (en)chondromas, chondroblastomas, and chondromyxoid fibromas. This group includes common tumors, that is, osteochondroma and (en)chondro...

journal_title：Advances in anatomic pathology

authors： Romeo S,Hogendoorn PC,Dei Tos AP

更新日期：2009-09-01 00:00:00

abstract：:Pathology has benefited from advanced innovation with novel technology to implement a digital solution. Whole slide imaging is a disruptive technology where glass slides are scanned to produce digital images. There have been significant advances in whole slide scanning hardware and software that have allowed for ready...

journal_title：Advances in anatomic pathology

authors： Hanna MG,Parwani A,Sirintrapun SJ

更新日期：2020-07-01 00:00:00

abstract：:Ovarian lesions composed of spindle cells comprise a heterogeneous group; most are neoplastic but several non-neoplastic conditions are also composed of spindle cells. This review discusses the main differential diagnoses of an ovarian spindle cell lesion, especially concentrating on the recent literature. The majorit...

journal_title：Advances in anatomic pathology

authors： Irving JA,McCluggage WG

更新日期：2007-09-01 00:00:00