The asthma consultation: what is important?

abstract：OBJECTIVE:To compare injection site pain of subcutaneous (sc) epoetin beta and darbepoetin alfa in adult patients with chronic kidney disease. RESEARCH DESIGN AND METHODS:This was a multi-centre, randomised, two-arm, single-blind, cross-over study. Patients were randomised to receive weekly sc darbepoetin alfa 30 mug ...

journal_title：Current medical research and opinion

authors： Roger SD,Suranyi MG,Walker RG,Disney A,Isbel NM,Kairaitis L,Pollock CA,Brown FG,Chow J,Truman MI,Ulyate KA,COMFORT study group.

更新日期：2008-08-01 00:00:00

abstract：:Type 2 diabetes mellitus is a public health problem of epidemic proportions and its prevalence is on the rise. The typical American born today has a one in three chance of developing type 2 diabetes. This diagnosis is associated with an adverse cardiovascular prognosis and is considered the risk equivalent of establis...

journal_title：Current medical research and opinion

authors： Abuissa H,Bel DS,O'keefe JH Jr

更新日期：2005-07-01 00:00:00

abstract：:The most common side-effect of statins, mainly during dose titration, is liver toxicity, In these cases, sufficient control of low density lipoprotein cholesterol (LDL-C) in patients with heterozygous familial hypercholesterolaemia (HFH) becomes problematical. In patients with intolerance to resins as well, especially...

journal_title：Current medical research and opinion

authors： Athyros VG,Papageorgiou AA,Demitriadis DS,Kontopoulos AG

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The relationship between chronic pancreatitis (CP) and subsequent pyogenic liver abscess (PLA) is not well understood. METHODS:We investigated the risk of PLA in patients with CP using inpatient claims data from the Taiwan National Health Insurance Program for the period 2000-2010. We identified 17,810 pati...

journal_title：Current medical research and opinion

authors： Tseng CW,Chen YT,Lin CL,Liang JA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to quantify the incidence of thromboembolic events (specifically, deep vein thromboses [DVT] and pulmonary embolism [PE]) in patients with cancer, and to examine the effects of a major clinical trial design and execution factors on those incidence rates. RESEARCH DESIGN AND ME...

journal_title：Current medical research and opinion

authors： Reynolds MW,Shibata A,Zhao S,Jones N,Fahrbach K,Goodnough LT

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The Physician Payments Sunshine Act, enacted in 2010, is intended to increase the transparency of relationships between US physicians and teaching hospitals and manufacturers of drugs, biologics, and medical devices. We examined current opinion regarding the impact of the Sunshine Act on peer-reviewed medical...

journal_title：Current medical research and opinion

authors： Toroser D,Robinson M,Gegner J,Smith G,Nilsen J,Hyatt L,Johnson T,Hassan A,Gatchalian C

更新日期：2016-01-01 00:00:00

abstract：:The bioavailability of ofloxacin after a single dose of one of two tablet formulations (200 or 400 mg) or a liquid formulation (1.67 mg/ml) was investigated in 24 healthy male volunteers in an open randomized, crossover design study with a 5-day wash-out period between doses. Plasma concentrations of ofloxacin were de...

journal_title：Current medical research and opinion

authors： Flor S,Beals B

更新日期：1991-01-01 00:00:00

abstract：:A study was carried out in general practice to assess the clinical effectiveness and tolerability of the oral cephalosporin, cefuroxime axetil, in the treatment of 369 patients presenting with acute infections of the upper respiratory tract. The main diagnoses were tonsillitis, pharyngitis, sinusitis and otitis media....

journal_title：Current medical research and opinion

authors： Griffiths GK,VandenBurg MJ,Wight LJ,Gudgeon AC,Kelsey M

更新日期：1987-01-01 00:00:00

abstract：:One hundred and eight patients who had been taking phenytoin for a year or more, either alone or in combination with other drugs, were examined for gum hypertrophy by three observers independently. Approximately 90% of the patients showed either mild or no gum hypertrophy and severe swelling occurred in only 1%. The o...

journal_title：Current medical research and opinion

authors： Grant RH,Parsonage MJ,Barot MH

更新日期：1988-01-01 00:00:00

abstract：:A double-blind, parallel-group study was carried out to compare the efficacy and tolerability of a controlled-release tablet formulation of trazodone with the standard trazodone tablet. Three hundred and forty-seven general practice patients with depressive symptoms were recruited into the trial. Patients were randoml...

journal_title：Current medical research and opinion

authors： Moon CA,Laws D,Stott PC,Hayes G

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is the most common cancer. Most cases of BCCs are treated with only optimal surgical resection. However, unresectable, locally advanced or metastatic tumors might have potential to progress. In this patient group, there is no standardized treatment approach. Vismodegib is a new sel...

journal_title：Current medical research and opinion

authors： Erdem GU,Sendur MA,Ozdemir NY,Yazıcı O,Zengin N

更新日期：2015-04-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia seen in clinical practice and has attracted much attention due to its association with a substantial mortality and morbidity, particularly from stroke, thromboembolism and heart failure. This Editorial Commentary provides a brief overview of the ...

journal_title：Current medical research and opinion

authors： Khoo CW,Lip GY

更新日期：2009-05-01 00:00:00

abstract：:Fifty-two patients suffering from presumed viral pharyngeal infection or tonsillitis were treated with either benzydamine or placebo oral rinse as a gargle at 3-hourly intervals in a randomized double-blind study. Patients on the active preparation experienced faster resolution of pain and dysphagia and at 7 days 88% ...

journal_title：Current medical research and opinion

authors： Whiteside MW

更新日期：1982-01-01 00:00:00

abstract：:Six patients suffering from rheumatoid arthritis with massive knee joint effusions were treated with single daily doses of 600 mg pirazolac, a novel non-steroidal anti-inflammatory drug, for 3 days. Before the first dose, 3 hours after the second and the third dose, specimens of plasma and synovial fluid were drawn si...

journal_title：Current medical research and opinion

authors： Kurowski M,Dunky A,Geddawi M

更新日期：1987-01-01 00:00:00

abstract：:Forty patients with definite or classical rheumatoid arthritis were entered for 3 months in a double-blind trial, 20 patients each on 200 mg flurbiprofen or 4.0 g enteric-coated aspirin daily. Statistically significant improvements (Page Test, p less than 0.05) on flurbiprofen were reported during the course of the st...

journal_title：Current medical research and opinion

authors： Dequeker J,Mardjuardi A

更新日期：1981-01-01 00:00:00

abstract：:Neuroprotective agents inhibit reactions in the brain ischaemic injury cascade which lead to neuronal death. Gamma-aminobutyric acid (GABA) is a naturally occurring inhibitory neurotransmitter that increases chloride influx into the neuron and counteracts the toxic effects of glutamate. Clomethiazole is a GABA(A) agon...

journal_title：Current medical research and opinion

authors： Vaishnav A,Lutsep HL

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Tobacco smoking is a major risk factor for cardiovascular disease, respiratory disease and cancer and, for current smokers, smoking cessation is one of the most effective therapeutic interventions for reducing the risk of all-cause morbidity and mortality. However, smoking cessation causes nicotine withdrawa...

journal_title：Current medical research and opinion

authors： Aubin HJ

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Pharmaceutical preparations of human menopausal gonadotrophin (hMG), urine-derived follicle-stimulating hormone (u-FSH) and highly purified u-FSH (u-FSH-HP) have been available since the early 1960s and the mid 1980s and 1990s, respectively. Another commercial preparation of u-FSH-HP, Folyrmon P, was launched...

journal_title：Current medical research and opinion

authors： Bassett R,Ceccarelli D,Crisci C,di Tria AM,Mancinelli M,Martelli F,Mendola D,Pezzotti A

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Stroke is a major cause of disability. Certain experimental studies have suggested that a combination of almitrine + raubasine (Duxil) increases the supply of oxygen to cerebral tissues and may be beneficial in post-stroke rehabilitation. This multicentre clinical study was carried out in orde...

journal_title：Current medical research and opinion

authors： Li S,Long J,Ma Z,Xu Z,Li J,Zhang Z

更新日期：2004-03-01 00:00:00

abstract：:A clinical trial was undertaken in 50 patients with osteoarthritis of the knee to assess the therapeutic value of glycosaminoglycan-peptide complex in treatment. The first year consisted of a randomized, double-blind, placebo-controlled, parallel-group trial (25 patients in each group), after which all patients receiv...

journal_title：Current medical research and opinion

authors： Katona G

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the safety and clinical efficacy of alcaftadine 0.25% ophthalmic solution, a new topical anti-allergic agent for the prevention of the signs and symptoms of allergic conjunctivitis induced by conjunctival allergen challenge (CAC). STUDY DESIGN AND METHODS:This two-ar...

journal_title：Current medical research and opinion

authors： Torkildsen G,Shedden A

更新日期：2011-03-01 00:00:00

abstract：AIM:The aim of this case series was to report the use of 8% topical capsaicin patch (marketed under the trade name Qutenza®) a in the management of refractory neuropathic pain (NP) in adult patients with type 1 neurofibromatosis (NF1). METHODS:Capsaicin has been suggested for NF1 patients suffering from refractory per...

journal_title：Current medical research and opinion

authors： Bardo-Brouard P,Luizard C,Valeyrie-Allanore L,Goujon C,Do B,Colin A,Wolkenstein P,Paul M

更新日期：2018-05-01 00:00:00

abstract：:Objective: Type 2 diabetes (T2D) is a prevalent health problem. Oral agents, with the exception of metformin, are often discontinued with the initiation of insulin. The objective was to understand the proportion of patients discontinuing dipeptidyl peptidase-4 inhibitors (DPP-4is) and the reasons for the decision to d...

journal_title：Current medical research and opinion

authors： Fernandes G,Matos JE,Jaffe DH,Beyer G,Yang L,Iglay K,Gantz I,Rajpathak S

更新日期：2020-03-01 00:00:00

abstract：:A double-blind trial was carried out in 37 patients with osteoarthrosis to compare the efficacy and tolerance of 250 mg diflunisal twice daily with that of 400 mg ibuprofen 3-times daily over an 8-week period. Rating scale assessments were made, at the end of a preceding 1-week, wash-out period on placebo and at regul...

journal_title：Current medical research and opinion

authors： Bresnihan B,Hughes G,Essigman WK

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:To review published evidence on the impact of weight/BMI change on health-related quality of life (HRQoL) in adults from the US with overweight/obesity. METHODS:The systematic review was conducted in accordance with PRISMA guidelines. MEDLINE, Embase, EconLit, and Cochrane Library databases were reviewed usi...

journal_title：Current medical research and opinion

authors： Kroes M,Osei-Assibey G,Baker-Searle R,Huang J

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of intranasal fentanyl spray (INFS), oral transmucosal fentanyl citrate (OTFC), fentanyl buccal tablet (FBT) and oral morphine (OM) for the treatment of breakthrough cancer pain (BTCP). METHODS:A systematic literature review (Medline, EMBASE, BIOSIS; 1996-2007) identified six randomis...

journal_title：Current medical research and opinion

authors： Vissers D,Stam W,Nolte T,Lenre M,Jansen J

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:While arterial wall imaging has been used to characterize progression of atherosclerosis, there remain limitations to this approach. SCOPE:A selective overview of emerging modalities to image the artery wall and highlight how they may be used to evaluate emerging anti-atherosclerotic agents. FINDINGS:Ongoi...

journal_title：Current medical research and opinion

authors： Bayturan O,Uno K,Lavoie A,Nicholls SJ

更新日期：2010-03-01 00:00:00

abstract：:A randomized, double-blind study was carried out in 24 patients with stable angina pectoris to compare the efficacy of nadolol, a new beta-adrenoceptor antagonist, and propranolol. After a period on placebo, 14 patients received nadolol once daily and 10 patients propranolol 4-times daily over a 10-week dose-ranging p...

journal_title：Current medical research and opinion

authors： Furberg B,Dahlqvist A,Raak A,Wrege U

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Undetected/uncontrolled diabetes is associated with substantial morbidity and mortality and consequent costs. Early detection through screening identifies patients at risk, allowing for earlier treatment initiation. OBJECTIVES:To determine the economic impact of screening for type 2 diabetes (T2DM). DATA S...

journal_title：Current medical research and opinion

authors： Einarson TR,Bereza BG,Acs A,Jensen R

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:This survey assessed the impact of symptoms of COPD on patients' ability to perform activities throughout the day and the extent to which physicians provided advice including how medications may help maintain quality of life. METHODS:The survey had three inclusion criteria--physician's diagnosis of COPD, ag...

journal_title：Current medical research and opinion

authors： O'Hagan P,Chavannes NH

更新日期：2014-02-01 00:00:00