Abstract:
:The efficacy of oxime (HI-6, toxogonin or PAM Cl) therapy against GF (cyclohexyl methylphosphonofluoridate) poisoning was assessed in mice. It was found that the combinations of atropine and either toxogonin or HI-6 were effective therapies against GF poisoning. PAM therapy was ineffective. HI-6 was the only oxime which reactivated GF inhibited acetylcholinesterase. This might explain the reason why the HI-6 treated mice appeared to recover more quickly from the incapacitating effects following GF poisoning.
journal_name
Arch Toxicoljournal_title
Archives of toxicologyauthors
Clement JGdoi
10.1007/BF02342509keywords:
subject
Has Abstractpub_date
1992-01-01 00:00:00pages
143-4issue
2eissn
0340-5761issn
1432-0738journal_volume
66pub_type
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