Abstract:
PURPOSE:Studies have shown a high prevalence of weight loss in older adults is associated with an increased risk of death. We investigated this in a population-based study. METHODS:Persons living in Beaver Dam, Wisconsin, participated in a baseline examination between 1988 and 1990 (n=4926). A medical examination and standardized questionnaire were administered. Weight loss was defined as percent loss in body weight from highest lifetime weight to measured weight at baseline. RESULTS:Weight loss was associated with older age, higher rates of diseases such as diabetes, and lower baseline levels of blood pressure and serum total cholesterol. After controlling for age, medical, and lifestyle factors, both men and women had higher mortality rates over a 10+ year period for increasing categories of weight loss (hazard ratio [ 95% CI]: 1.16 [1.06, 1.27] for men and 1.23 [1.13, 1.34] for women). Increased mortality rates with increasing weight loss was shown in stratified analyses of age, body mass index (BMI) at highest weight, smoking, and disease status, but did not always reach statistical significance. Persons on weight loss diets within the year prior to baseline did not have increased mortality with increasing weight loss. CONCLUSION:The strong association between weight loss (likely involuntary) and mortality may be a useful way of estimating overall risks to longevity in populations.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Knudtson MD,Klein BE,Klein R,Shankar Adoi
10.1016/j.annepidem.2004.12.003keywords:
subject
Has Abstractpub_date
2005-08-01 00:00:00pages
483-91issue
7eissn
1047-2797issn
1873-2585pii
S1047-2797(05)00004-9journal_volume
15pub_type
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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journal_title:Annals of epidemiology
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更新日期:2009-08-01 00:00:00
abstract:PURPOSE:To examine associations between racial discrimination, mood disorders, and cardiovascular disease (CVD) among Black Americans. METHODS:Weighted logistic regression analyses were performed on a nationally representative sample of Black Americans (n = 5022) in the National Survey of American Life (NSAL; 2001-200...
journal_title:Annals of epidemiology
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pub_type: 杂志文章
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pub_type: 历史文章,杂志文章
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更新日期:2019-09-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.09.003
更新日期:2012-01-01 00:00:00
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更新日期:2019-05-01 00:00:00
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2003.08.003
更新日期:2004-03-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2017.12.001
更新日期:2018-02-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2015-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:1994-07-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.07.003
更新日期:2011-12-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2007.10.008
更新日期:2008-03-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:1993-09-01 00:00:00
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更新日期:2010-02-01 00:00:00
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journal_title:Annals of epidemiology
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更新日期:2013-01-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2013-05-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2004.09.003
更新日期:2005-05-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2014.02.012
更新日期:2014-06-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2008.09.004
更新日期:2008-12-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2005.06.058
更新日期:2006-06-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(02)00271-5
更新日期:2003-04-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(99)00033-2
更新日期:2000-02-01 00:00:00
abstract:PURPOSE:To evaluate the association between active and passive smoking and frequency of colds in women. METHODS:Data on cigarette smoking and frequency and duration of colds were analyzed in the Women's Health Study (WHS), a randomized, double-blind, placebo-controlled trial of low-dose aspirin and vitamin E in the pr...
journal_title:Annals of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-05-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.10.011
更新日期:2012-02-01 00:00:00