Complications after unintentional intra-arterial injection of drugs: risks, outcomes, and management strategies.

Abstract:

:Unintentional intra-arterial injection of medication, either iatrogenic or self-administered, is a source of considerable morbidity. Normal vascular anatomical proximity, aberrant vasculature, procedurally difficult situations, and medical personnel error all contribute to unintentional cannulation of arteries in an attempt to achieve intravenous access. Delivery of certain medications via arterial access has led to clinically important sequelae, including paresthesias, severe pain, motor dysfunction, compartment syndrome, gangrene, and limb loss. We comprehensively review the current literature, highlighting available information on risk factors, symptoms, pathogenesis, sequelae, and management strategies for unintentional intra-arterial injection. We believe that all physicians and ancillary personnel who administer Intravenous therapies should be aware of this serious problem.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Sen S,Chini EN,Brown MJ

doi

10.1016/S0025-6196(11)61533-4

keywords:

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

783-95

issue

6

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)61533-4

journal_volume

80

pub_type

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