Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging.

abstract：:Clinical guidelines for instituting pharmacotherapy for the primary prevention of atherosclerotic cardiovascular disease (ASCVD), specifically lipid management and aspirin, have long been based on absolute risk. However, lipid management in the current era remains challenging to both patients and clinicians in the set...

journal_title：Mayo Clinic proceedings

authors： Michos ED,Blaha MJ,Blumenthal RS

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To study the relationship between body mass index (BMI) and central obesity and mortality in elderly patients with coronary artery disease (CAD). PATIENTS AND METHODS:We identified 7057 patients 65 years or older from 5 cohort studies assessing mortality risk using either waist circumference (WC) or waist-hi...

journal_title：Mayo Clinic proceedings

authors： Sharma S,Batsis JA,Coutinho T,Somers VK,Hodge DO,Carter RE,Sochor O,Kragelund C,Kanaya AM,Zeller M,Park JS,Køber L,Torp-Pedersen C,Lopez-Jimenez F

更新日期：2016-03-01 00:00:00

abstract：:Extending a study of the period 1935-1964, we determined the incidence rates of leukemia in Olmsted County during the decade 1965-1974. In this decade, the overall crude annual incidence rate was 9.5 per 100,000. The ratio of males to females was 2.4 to 1; and the incidence rate was significantly higher among males th...

journal_title：Mayo Clinic proceedings

authors： Linos A,Kyle RA,Elveback LR,Kurland LT

更新日期：1978-11-01 00:00:00

abstract：:Myoclonus is defined as sudden, brief, shocklike, involuntary movements caused by muscular contractions or inhibitors. Myoclonic movements have now been recognized to have many possible variants and pathophysiologic features. Myoclonus may arise from several sites within the neuraxis, of which the cortex and brain ste...

journal_title：Mayo Clinic proceedings

authors： Caviness JN

更新日期：1996-07-01 00:00:00

abstract：:Between Jan. 1, 1976, and Dec. 31, 1985, at our institution, 37 patients who had undergone prior complete surgical resection of non-small-cell lung cancer received definitive thoracic radiation therapy (TRT) for locally recurrent disease. Of the 37 recurrences, 33 were in the pulmonary parenchyma or the hilar, mediast...

journal_title：Mayo Clinic proceedings

authors： Shaw EG,Brindle JS,Creagan ET,Foote RL,Trastek VF,Buskirk SJ

更新日期：1992-12-01 00:00:00

abstract：:B-cell chronic lymphocytic leukemia (B-CLL) is a relatively indolent hematologic malignant disease that, despite a good response to nonaggressive orally administered chemotherapy, currently remains incurable. The overall median duration of survival is more than 5 years, and the presence of anemia or thrombocytopenia a...

journal_title：Mayo Clinic proceedings

authors： Tefferi A,Phyliky RL

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the rate of and potential risk factors for bloodstream infections (BSIs) using data from the REVEAL (Registry to Evaluate Early and Long-term Pulmonary Arterial Hypertension [PAH] Disease Management) REGISTRY(®), which provides current information about patients with PAH. PATIENTS AND METHODS:Pat...

journal_title：Mayo Clinic proceedings

authors： Kitterman N,Poms A,Miller DP,Lombardi S,Farber HW,Barst RJ

更新日期：2012-09-01 00:00:00

abstract：:Considerable advances in the diagnosis and treatment of migraine headache have occurred during the past decade, but treatment options for acute migraine attacks have expanded at a faster rate than those for prophylaxis. We describe a patient whose migraine headaches responded dramatically to sustained-release niacin a...

journal_title：Mayo Clinic proceedings

authors： Velling DA,Dodick DW,Muir JJ

更新日期：2003-06-01 00:00:00

abstract：:Abdominal apoplexy is a clinical entity characterized by spontaneous intraperitoneal hemorrhage from rupture of a visceral vessel. We describe a 34-year-old man who presented with abdominal apoplexy due to rupture of an ileocolic aneurysm. Subsequent biochemical and genetic analysis confirmed the diagnosis of Ehlers-D...

journal_title：Mayo Clinic proceedings

authors： Hassan I,Rasmussen TE,Schwarze U,Rose PS,Whiteman DA,Gloviczki P

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To verify preliminary studies on patients with melanoma exposed to β-blockers that suggested a reduced risk of disease recurrence and death. PATIENTS AND METHODS:Data were obtained from all consecutive patients diagnosed as having melanoma between January 1, 1993, and December 31, 2009, at the Department of ...

journal_title：Mayo Clinic proceedings

authors： De Giorgi V,Gandini S,Grazzini M,Benemei S,Marchionni N,Geppetti P

更新日期：2013-11-01 00:00:00

abstract：:A 4 1/2-year-old girl is described in whom the portal vein is absent and the venous return from the gastrointestinal tract, spleen, and pancreas is through the left renal vein into the inferior vena cava. She had a hepatoblastoma, which was treated surgically by right hepatic lobectomy. Regeneration occurred in the re...

journal_title：Mayo Clinic proceedings

authors： Marois D,van Heerden JA,Carpenter HA,Sheedy PF 2nd

更新日期：1979-01-01 00:00:00

abstract：:For primary care physicians, obesity is one of the most challenging problems confronted in office practice. The disorder is Increasing in prevalence despite the efforts of both patients and physicians. Treatment requires a multimodality approach that addresses diet, physical activity, and behavioral issues. Medication...

journal_title：Mayo Clinic proceedings

authors： Thompson WG,Cook DA,Clark MM,Bardia A,Levine JA

更新日期：2007-01-01 00:00:00

abstract：:During the 1960s, the Mustard or Senning operation was the conventional palliative therapy for patients with transposition of the great arteries. Many of these patients are now adults, and the durability of the morphologic right ventricle to function as the systemic ventricle is being questioned. Surgical options for ...

journal_title：Mayo Clinic proceedings

authors： Cetta F,Bonilla JJ,Lichtenberg RC,Stasior C,Troman JE,Deleon SY

更新日期：1997-03-01 00:00:00

abstract：:Thirty-five patients with a diagnosis of pure ovarian dysgerminoma underwent assessment at our institution between 1950 and 1984. The median age of these patients was 21 years (range, 8 to 41 years). The surgical pathologic stages of the tumors were as follows: stage IA1 in 18 patients, stage IA2 in 2, stage IB1 in 2,...

journal_title：Mayo Clinic proceedings

authors： Buskirk SJ,Schray MF,Podratz KC,Lee RA,Stanhope CR,Gaffey TA,Weber FC,Earle JD,Naessens JM,Malkasian GD

更新日期：1987-12-01 00:00:00

abstract：:Effective antimicrobial therapy for most urinary tract infections has been available since the sulfonamide era. Innovations in chemotherapy now include single-dose treatment of acute bacterial cystitis and acute urethral syndrome and effective suppression of recurrent bacteriuria with low-dose antimicrobial agents. ...

journal_title：Mayo Clinic proceedings

authors： Keys TF,Edson RS

更新日期：1983-03-01 00:00:00

abstract：:Epilepsy is a common condition that affects 0.5 to 1% of all children. Although most children with epilepsy have well-controlled seizures with use of one antiepileptic drug (AED), some children have medically refractory seizures. This situation can be the result of inaccurate classification of the paroxysmal event, us...

journal_title：Mayo Clinic proceedings

authors： Zupanc ML

更新日期：1996-09-01 00:00:00

abstract：:In a prospective study of 10 patients who underwent liver transplantation and 10 patients who underwent cholecystectomy, we analyzed the postoperative analgesic requirements and the resultant plasma morphine concentrations. Analgesia was more intense, with less medication, and the plasma morphine concentration was sig...

journal_title：Mayo Clinic proceedings

authors： Eisenach JC,Plevak DJ,Van Dyke RA,Southorn PA,Danielson DR,Krom RA,Nagorney DM,Rettke SR

更新日期：1989-03-01 00:00:00

abstract：:This discussion concerns an overview of our considerations of the adrenergic nervous system with respect to those areas of the nervous system that provide direct sensory input to the brain in control of arterial pressure; those brain centers that also participate in regulating arterial pressure; certain neurohumoral c...

journal_title：Mayo Clinic proceedings

authors： Frohlich ED

更新日期：1977-06-01 00:00:00

abstract：:Pyoderma gangrenosum is a painful, noninfectious, ulcerating skin disorder often associated with systemic disease. Thalidomide has been used to treat many inflammatory dermatologic conditions and has been reintroduced in the United States to treat immune-modulated diseases such as pyoderma gangrenosum. The patient des...

journal_title：Mayo Clinic proceedings

authors： Federman GL,Federman DG

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To compare all-cause mortality rates across the severity range of white matter hyperintensities (WMH). PATIENTS AND METHODS:Between October 26, 2010, and October 5, 2017, the ongoing Mayo Clinic Florida Familial Cerebrovascular Diseases Registry prospectively enrolled 1011 diverse participants with and witho...

journal_title：Mayo Clinic proceedings

authors： Hasan TF,Barrett KM,Brott TG,Badi MK,Lesser ER,Hodge DO,Meschia JF

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:To evaluate, in this before-and-after study, the results of 5 strategies for improving attendance at medical grand rounds at a tertiary care academic medical center. METHODS:The strategies included (1) using electronic card readers to improve understanding of attendance patterns, (2) conducting yearly needs ...

journal_title：Mayo Clinic proceedings

authors： Mueller PS,Litin SC,Sowden ML,Habermann TM,LaRusso NF

更新日期：2003-05-01 00:00:00

abstract：:Thalamic deep brain stimulation is becoming increasingly popular for the control of drug-refractory tremor. Implantable cardiac pacemakers and defibrillators are commonly used therapeutic modalities. Concerns exist about the potential interactions between these 2 devices in the same patient, but no experience has been...

journal_title：Mayo Clinic proceedings

authors： Obwegeser AA,Uitti RJ,Turk MF,Wszolek UM,Flipse TR,Smallridge RC,Witte RJ,Wharen RE Jr

更新日期：2001-01-01 00:00:00

abstract：:Clopidogrel bisulfate, a widely used inhibitor of platelet aggregation, is considered at least as safe as aspirin. We describe a patient who developed a systemic inflammatory response syndrome consisting of high fever, tachycardia, cellulitis-like rash, impaired liver function, and mild leukopenia after receiving clop...

journal_title：Mayo Clinic proceedings

authors： Wolf I,Mouallem M,Rath S,Farfel Z

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVES:To document the prevalence of use of herbal products among adults in a large metropolitan area and to examine issues surrounding such use. SUBJECTS AND METHODS:Of people aged 18 years and older residing in the Minneapolis/St Paul, Minn, metropolitan area, 752 were randomly selected from Minnesota Department...

journal_title：Mayo Clinic proceedings

authors： Harnack LJ,Rydell SA,Stang J

更新日期：2001-07-01 00:00:00

abstract：:During the 11-year period 1975 through 1985, 1,063 surgical procedures were performed on 795 Mayo Clinic patients 90 years of age or older. Preoperative conditions, surgical setting, and perioperative morbidity and mortality were analyzed in a comparison of the local residents of Olmsted County, Minnesota (N = 224), w...

journal_title：Mayo Clinic proceedings

authors： Warner MA,Hosking MP,Lobdell CM,Offord KP,Melton LJ 3rd

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVE:To determine the effects of cardiac rehabilitation interventions on patients with hostility, or unexpressed anger, a coronary heart disease risk factor that adversely affects morbidity and mortality after major coronary heart disease events. METHODS:Using validated questionnaires to evaluate behavioral chara...

journal_title：Mayo Clinic proceedings

authors： Lavie CJ,Milani RV

更新日期：1999-10-01 00:00:00

abstract：:Aerobic exercise training has been used as part of the treatment for a variety of chronic disorders, most notably cardiovascular disease. In order to determine the feasibility and utility of regular exercise after renal transplantation, the responses of 10 patients to graded exercise testing were compared before train...

journal_title：Mayo Clinic proceedings

authors： Miller TD,Squires RW,Gau GT,Ilstrup DM,Frohnert PP,Sterioff S

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:To assess the frequency and significance of GB virus-C infection in type 1 autoimmune hepatitis. MATERIAL AND METHODS:Serum specimens from 94 patients with type 1 autoimmune hepatitis were tested for GB virus-C RNA by reverse transcription and polymerase chain reaction. Serum samples from 50 normal subjects ...

journal_title：Mayo Clinic proceedings

authors： Czaja AJ,Abdulkarim AS,Carpenter HA,Perez RG,Persing DH,Zein NN

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:The efficacy of fine-needle aspiration (FNA) biopsy and its role in the management of a nodular goiter are clearly established. The accuracy of cytologic diagnosis approaches 95%. FINDINGS:FNA biopsy is a reasonable approach to thyroid nodules; it has decreased costs substantially because it facilitates sel...

journal_title：Mayo Clinic proceedings

authors： Gharib H

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To identify and assess the impact of postoperative complications in patients with unrecognized or known obstructive sleep apnea syndrome (OSAS) undergoing hip replacement or knee replacement compared with control patients undergoing similar operations. Although OSAS is a risk factor for perioperative morbidit...

journal_title：Mayo Clinic proceedings

authors： Gupta RM,Parvizi J,Hanssen AD,Gay PC

更新日期：2001-09-01 00:00:00