Abstract:
:During the 11-year period 1975 through 1985, 1,063 surgical procedures were performed on 795 Mayo Clinic patients 90 years of age or older. Preoperative conditions, surgical setting, and perioperative morbidity and mortality were analyzed in a comparison of the local residents of Olmsted County, Minnesota (N = 224), with patients from outside the county but within 250 miles (N = 456) or referrals from a distance of 250 miles or further (N = 115). In comparison with non-Olmsted County patients, Olmsted County patients were generally older, had more preoperative chronic diseases, and underwent more emergency operations. Patients who had traveled 250 miles or more to the Mayo Clinic were more likely to be men and referred for cancer-related surgical procedures. The risks of major morbidity and mortality within 48 hours postoperatively were increased in patients with more preoperative chronic diseases and those undergoing emergency procedures, characteristics most common in Olmsted County patients. Because of differences in these factors between groups, perioperative risks averaged over our entire patient series underestimated risks that would be expected from a population-based cohort such as Olmsted County residents. In general, data from tertiary medical centers probably do not accurately reflect overall practice or outcomes in community settings.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Warner MA,Hosking MP,Lobdell CM,Offord KP,Melton LJ 3rddoi
10.1016/s0025-6196(12)62742-6subject
Has Abstractpub_date
1990-09-01 00:00:00pages
1185-91issue
9eissn
0025-6196issn
1942-5546pii
S0025-6196(12)62742-6journal_volume
65pub_type
杂志文章abstract::Two cases are presented and a third is cited from the literature in which the onset of hyperthyroidism exacerbated acute weakness in previously undiagnosed myotonic dystrophy. In two of the cases a return to the euthyroid state after treatment was associated with marked clinical improvement in muscle weakness. In the ...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract:OBJECTIVE:To explore the current epidemiological profile of Marfan syndrome in a general population. PATIENTS AND METHODS:Patients who had received a diagnosis of Marfan syndrome were identified from the Taiwan National Health Insurance database records from January 1, 2000, through December 31, 2012 (average populati...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/j.mayocp.2013.08.022
更新日期:2014-01-01 00:00:00
abstract::Noninvasive ventilation refers to the delivery of assisted ventilatory support without the use of an endotracheal tube. Noninvasive positive pressure ventilation (NPPV) can be delivered by using a volume-controlled ventilator, a pressure-controlled ventilator, a bilevel positive airway pressure ventilator, or a contin...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.4065/74.8.817
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the rate of and potential risk factors for bloodstream infections (BSIs) using data from the REVEAL (Registry to Evaluate Early and Long-term Pulmonary Arterial Hypertension [PAH] Disease Management) REGISTRY(®), which provides current information about patients with PAH. PATIENTS AND METHODS:Pat...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,多中心研究
doi:10.1016/j.mayocp.2012.05.014
更新日期:2012-09-01 00:00:00
abstract::The metabolic syndrome is an insulin-resistant state characterized by a cluster of cardiovascular risk factors, including various combinations of abdominal obesity, glucose intolerance, hypertension, and atherogenic dyslipidemia (elevated triglyceride values, low high-density lipoprotein cholesterol levels, and small ...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.4065/81.12.1615
更新日期:2006-12-01 00:00:00
abstract::Pergolide is a potent dopamine agonist and is known to have anti-Parkinson properties. We administered pergolide to patients with suboptimal control of Parkinson's disease who had a short-duration response to carbidopa-levodopa in a 6-month, double-blind study. Pergolide added to the carbidopa-levodopa regimen resulte...
journal_title:Mayo Clinic proceedings
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0025-6196(12)64911-8
更新日期:1988-10-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy of brief couples support groups offered concurrently with in vitro fertilization (IVF) treatment. PATIENTS AND METHODS:Couples in IVF treatment were given the option of participating in a biweekly support group at the IVF clinic at Wilford Hall Medical Center, San Antonio, Tex. At leas...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/77.10.1060
更新日期:2002-10-01 00:00:00
abstract::Crohn's disease can involve any portion of the digestive tract, but isolated gastric Crohn's disease is a rare entity. In the few previously reported cases, the inflammatory disorder has involved only a portion of the stomach. Herein we describe a patient with diffuse involvement of the entire stomach and an associate...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)61750-9
更新日期:1989-07-01 00:00:00
abstract::Between Jan. 1, 1976, and Dec. 31, 1985, at our institution, 37 patients who had undergone prior complete surgical resection of non-small-cell lung cancer received definitive thoracic radiation therapy (TRT) for locally recurrent disease. Of the 37 recurrences, 33 were in the pulmonary parenchyma or the hilar, mediast...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)61141-0
更新日期:1992-12-01 00:00:00
abstract::There are a number of changes underway in modern clinical bacteriology laboratories. Panel-based molecular diagnostics are now available for numerous applications, including, but not limited to, detection of bacteria and select antibacterial resistance markers in positive blood culture bottles, detection of acute gast...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.mayocp.2016.06.020
更新日期:2016-10-01 00:00:00
abstract::Prompt and appropriate management measures are critical in order to achieve a favorable outcome after a major overdose of intrathecally (IT) administered methotrexate (MTX). Published information available to guide clinicians in the immediate management of this medical emergency is scant. Herein we describe a 6-year-o...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/71.2.161
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVE:To determine the percentage of metastatic and unexpected residual lung cancer at autopsy in patients considered for curative resection of non-small cell lung cancer during a time when computed tomography was available as a preoperative staging tool. MATERIAL AND METHODS:Clinical data and surgical and autopsy...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/79.11.1409
更新日期:2004-11-01 00:00:00
abstract::In this article, we describe an integrated approach for detection and evaluation of solitary pulmonary nodules. Initial evaluation of the solitary pulmonary nodule includes tomography, fluoroscopy, and comparison with previously obtained roentgenograms. Subsequently, thin-section computed tomography and phantom densit...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/s0025-6196(12)65012-5
更新日期:1990-02-01 00:00:00
abstract:OBJECTIVE:To assess the association between exercise capacity and the risk of developing atrial fibrillation (AF). PATIENTS AND METHODS:A symptom-limited exercise tolerance test was conducted to assess exercise capacity in 5962 veterans (mean age, 56.8±11.0 years) from the Veterans Affairs Medical Center, Washington, ...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/j.mayocp.2016.03.002
更新日期:2016-05-01 00:00:00
abstract::Data from animal experiments and human studies implicate added sugars (eg, sucrose and high-fructose corn syrup) in the development of diabetes mellitus and related metabolic derangements that raise cardiovascular (CV) risk. Added fructose in particular (eg, as a constituent of added sucrose or as the main component o...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.mayocp.2014.12.019
更新日期:2015-03-01 00:00:00
abstract::The source of the membranous materials that accumulate in distal axons of rats intoxicated with p-bromophenylacetylurea (BPAU) was studied by electron microscopy. 35S-Methionine was injected into the ventral horn of the spinal cord at 2, 14, and 35 days after injection of BPAU. Three days later, samples of the deep pe...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)61550-x
更新日期:1992-04-01 00:00:00
abstract::Genitourinary syndrome of menopause (GSM), previously known as atrophic vaginitis or vulvovaginal atrophy, affects more than half of postmenopausal women. Caused by low estrogen levels after menopause, it results in bothersome symptoms, including vaginal dryness, itching, dyspareunia, urinary urgency and increased fre...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.mayocp.2017.08.019
更新日期:2017-12-01 00:00:00
abstract::Migraine, an episodic headache disorder, is one of the most common complaints encountered by primary-care physicians and neurologists. Nevertheless, it remains underdiagnosed and undertreated. Rational migraine treatment necessitates an accurate diagnosis, identification and removal of potential triggering factors, an...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.4065/71.11.1055
更新日期:1996-11-01 00:00:00
abstract::There is overwhelming evidence that racial and ethnic minorities face multiple health care disparities. Recognizing and addressing cultural and religious/spiritual (RS) values is a critical aspect of providing goal-concordant care for patients facing a serious illness, especially at the end of life. Failure to address...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.1016/j.mayocp.2016.08.024
更新日期:2017-01-01 00:00:00
abstract::Although transthoracic two-dimensional echocardiography has been a procedure of choice for diagnosing cardiac mass lesions, the advent of transesophageal echocardiography (TEE) provided better visualization of cardiac structures, especially those at a considerable depth from the chest wall, and lesions that involve th...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)65788-7
更新日期:1991-11-01 00:00:00
abstract::Two cases of rare, catastrophic calcium emboli to the coronary arteries immediately after percutaneous mitral balloon valvuloplasty are presented. Preoperative echocardiographic findings may identify patients at risk for this complication. These cases should increase the awareness of calcium emboli and lead to conside...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/76.7.753
更新日期:2001-07-01 00:00:00
abstract::In order to test the safety of hot tub use for persons with heart disease, 15 men with clinically stable coronary artery disease underwent 15 minutes of immersion in a hot tube at 40 degrees C. On another day, they exercised on a cycle ergometer for 15 minutes; target heart rate was determined by standard methods. Tym...
journal_title:Mayo Clinic proceedings
pub_type: 临床试验,杂志文章
doi:10.1016/s0025-6196(12)60014-7
更新日期:1993-01-01 00:00:00
abstract::Epilepsy is one of the most common and challenging neurologic disorders affecting children. Although various modalities exist to treat pediatric-onset seizures, seizures in 25% of children who are diagnosed as having epilepsy remain refractory to available therapies. Of the 8 new antiepileptic drugs (AEDs) (felbamate,...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.4065/78.3.359
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:To describe clinical, radiological, and histopathologic features of diffuse bronchiolar disease due to chronic occult aspiration. PATIENTS AND METHODS:We identified 4 patients encountered from July 2001 to January 2004 who had persistent respiratory symptoms and lung Infiltrates and who were eventually diagn...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/81.2.172
更新日期:2006-02-01 00:00:00
abstract::Frequently, the presence of endocarditis is disguised. The emphasis of this description of the clinical manifestations of endocarditis is on the various modes of presentation, rather than on individual symptoms and signs. Endocarditis can manifest with cardiac, pulmonary, ophthalmic, central nervous system, renal, ort...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::A 27-year-old man was treated for an aggressive cerebellar medulloblastoma that, at operation, exhibited dural invasion. Six months after gross total resection and radiation therapy, a "surgical metastasis" developed in the lower portion of the surgical scar. The tumor grew rapidly down into the right side of his neck...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)62221-6
更新日期:1994-04-01 00:00:00
abstract:OBJECTIVE:To assess obesity rates during childhood and young adulthood in patients with attention-deficit/hyperactivity disorder (ADHD) and age- and sex-matched controls derived from a population-based birth cohort because cross-sectional studies suggest an association between ADHD and obesity. PATIENTS AND METHODS:St...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/j.mayocp.2015.09.017
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To study the direct physiological and emotional impact of an animal-assisted activity (AAA) session (a form of complementary and integrative medicine) in patients with fibromyalgia (FM). PATIENTS AND METHODS:The study population consisted of 221 participants with FM who were attending Mayo Clinic's Fibromyal...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.mayocp.2020.04.037
更新日期:2020-11-01 00:00:00
abstract::The clinical and morphologic findings of allergic granulomatosis and angiitis of Churg and Strauss in 21 men and 9 women were reviewed. The classic features are those of systemic vasculitis in a setting of bronchial asthma and eosinophilia. Pathologically there is necrotizing vasculitis of small arteries and veins wit...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1977-08-01 00:00:00
abstract::Advances in liver transplantation continue to evolve but are hampered by continued increasing shortages in donor organs. This has resulted in a high incidence of patients dying while on the United Network for Organ Sharing waiting list. Indeed, we continue to assess ways of expanding the donor pool by using marginal d...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
doi:10.4065/78.2.197
更新日期:2003-02-01 00:00:00