Abstract：
:Two cases are presented and a third is cited from the literature in which the onset of hyperthyroidism exacerbated acute weakness in previously undiagnosed myotonic dystrophy. In two of the cases a return to the euthyroid state after treatment was associated with marked clinical improvement in muscle weakness. In the third case, severe bulbar and respiratory muscle weakness, which was apparently aggravated by the thyrotoxicosis, was followed by aspiration pneumonitis and death. Possible mechanisms for the effect of excessive thyroxine on muscle function are reviewed. Early diagnosis and aggressive treatment of the hyperthyroidism is extremely important.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Peterson DM,Bounds JV Jr,Karnes WEkeywords:
subject
Has Abstractpub_date
1976-03-01 00:00:00pages
176-9issue
3eissn
0025-6196issn
1942-5546journal_volume
51pub_type
杂志文章abstract：OBJECTIVE:To evaluate the outcomes of robotic mitral valve repair (MVr) by primary indication per American Heart Association guidelines for surgery: class I vs class IIa. PATIENTS AND METHODS:From January 1, 2008, through September 30, 2016, 603 patients underwent robotic MVr for severe primary mitral regurgitation. M...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2019.05.025
更新日期：2019-11-01 00:00:00
abstract：:Although transthoracic two-dimensional echocardiography has been a procedure of choice for diagnosing cardiac mass lesions, the advent of transesophageal echocardiography (TEE) provided better visualization of cardiac structures, especially those at a considerable depth from the chest wall, and lesions that involve th...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)65788-7
更新日期：1991-11-01 00:00:00
abstract：:Prompt and appropriate management measures are critical in order to achieve a favorable outcome after a major overdose of intrathecally (IT) administered methotrexate (MTX). Published information available to guide clinicians in the immediate management of this medical emergency is scant. Herein we describe a 6-year-o...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/71.2.161
更新日期：1996-02-01 00:00:00
abstract：OBJECTIVE:To assess whether patients with pancreatic cancer-associated pain living near a pain control center were more likely to undergo neurolytic celiac plexus block (NCPB) than those living at a distance and to determine the rationale of physicians at our institution for referring patients for NCPB. DESIGN:We retr...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/72.9.831
更新日期：1997-09-01 00:00:00
abstract：OBJECTIVE:To determine whether dehydroepiandrosterone (DHEA) replacement therapy in hypoadrenal women improves performance, muscle protein accretion, and mitochondrial functions. PARTICIPANTS AND METHODS:Thirty-three hypoadrenal women were enrolled in the study from May 1, 2002, through May 31, 2003. Twenty-eight comp...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,随机对照试验
doi：10.4065/83.11.1218
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVES:To characterize public perception of physicians' conflicts of interest (COIs) across medical and surgical specialties. PATIENTS AND METHODS:A cross-sectional 6-arm randomized survey of a nonprobability sample from Amazon's Mechanical Turk occurred on December 11 to 16, 2018. Survey respondents were randomly...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2019.07.009
更新日期：2019-12-01 00:00:00
abstract：:The clinical and morphologic findings of allergic granulomatosis and angiitis of Churg and Strauss in 21 men and 9 women were reviewed. The classic features are those of systemic vasculitis in a setting of bronchial asthma and eosinophilia. Pathologically there is necrotizing vasculitis of small arteries and veins wit...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1977-08-01 00:00:00
abstract：:Nine patients with a progressive neurologic disorder that was characterized by mental deterioration, supranuclear vertical gaze paresis, and foam cells or sea-blue histiocytes in the bone marrow are described and compared with patients who were previously described as having " neurovisceral storage disease with vertic...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)61464-5
更新日期：1984-06-01 00:00:00
abstract：OBJECTIVE:To investigate the hypothesis that an increasing intake of alcohol accelerates the course of chronic pancreatitis. PATIENTS AND METHODS:In this retrospective record analysis and subsequent prospective follow-up of 372 patients with chronic pancreatitis, we separately compared the clinical course of chronic p...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/76.3.242
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVE:To compare the indications for hospital admission between current, former, and never smokers and to compare their costs per hospital admission, testing the hypothesis that the cost per hospital admission would be higher for smokers than for former and never smokers. PATIENTS AND METHODS:This study used a ret...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2018.02.022
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:To assess whether amiodarone, as part of a strategy to achieve sinus rhythm, is safe and effective compared with a placebo or rate control drug in patients with persistent atrial fibrillation (AF) of more than 30 days' duration. METHODS:Randomized controlled trials comparing amiodarone with a placebo or rate...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,meta分析
doi：10.1016/S0025-6196(11)61140-3
更新日期：2009-03-01 00:00:00
abstract：:Parasitic diseases affect more than 2 billion people globally and cause substantial morbidity and mortality, particularly among the world's poorest people. This overview focuses on the treatment of the major protozoan and helminth infections in humans. Recent developments in antiparasitic therapy include the expansion...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/mcp.2011.0203
更新日期：2011-06-01 00:00:00
abstract：:The surgical treatment of Crohn's disease is necessitated by complications of the disease or by failure of medical therapy. Despite the fact that the patients with Crohn's disease who undergo operation have the most severe spectrum of problems, about half these patients may never need a further procedure, and the mort...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)61933-8
更新日期：1986-04-01 00:00:00
abstract：:Since the early 1970s, investigators have been interested in the relationship between dietary marine fish oils and plasma lipoproteins. Previous studies have shown that consumption of a diet rich in marine fatty acids results in altered lipid profiles, prolonged bleeding times, reduced platelet aggregation, and decrea...
journal_title：Mayo Clinic proceedings
pub_type： 临床试验,杂志文章,评审
doi：10.1016/s0025-6196(12)61879-5
更新日期：1987-02-01 00:00:00
abstract：:Three patients who had coryneform bacterial endocarditis affecting a prosthetic valve are presented and 64 case reports are reviewed. Diagnostic difficulties occur because coryneform bacteria often are fastidiuos, with long incubation periods, and often contaminate blood cultures. Although some coryneform bacteria are...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:Extending a study of the period 1935-1964, we determined the incidence rates of leukemia in Olmsted County during the decade 1965-1974. In this decade, the overall crude annual incidence rate was 9.5 per 100,000. The ratio of males to females was 2.4 to 1; and the incidence rate was significantly higher among males th...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
abstract：OBJECTIVE:To estimate the magnitude of association between intraoperative hyperglycemia and perioperative outcomes in patients who underwent cardiac surgery. PATIENTS AND METHODS:We conducted a retrospective observational study of consecutive adult patients who underwent cardiac surgery between June 10, 2002, and Augu...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/80.7.862
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:To prospectively assess the safety and effectiveness of the investigational phosphodiesterase 5 inhibitor avanafil to treat erectile dysfunction in men with diabetes mellitus. PATIENTS AND METHODS:This 12-week, multicenter, double-blind, placebo-controlled study conducted between December 15, 2008, and Febru...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.mayocp.2012.06.016
更新日期：2012-09-01 00:00:00
abstract：:We developed and validated a radioimmunoassay for circulating human parathyroid hormone-related peptide (PTHrP), based on a commercial antiserum to the synthetic 1-34 fragment of PTHrP, 125I-Tyr degrees-PTHrP(1-34) as radioligand, and prior extraction of the native peptide from plasma with C-2 cartridges. We determine...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)62163-6
更新日期：1990-11-01 00:00:00
abstract：OBJECTIVE:To describe management of patients with permanent pacemaker (PPM)- and implantable cardioverter-defibrillator (ICD)-related endocarditis. PATIENTS AND METHODS:We retrospectively reviewed all cases of infection involving PPMs and ICDs among patients presenting to Mayo Clinic's site in Rochester, MN, between J...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/83.1.46
更新日期：2008-01-01 00:00:00
abstract：:Health-care organizations have recognized the need to prepare physicians for various leadership and management positions within their own institutions. In the past, those who desired further education had to search beyond the boundaries of their practice to fulfill this need. The demands of a dynamic and changing heal...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/S0025-6196(11)63574-X
更新日期：1997-07-01 00:00:00
abstract：:The issue of whether patients who have invasive carcinoma in an otherwise benign polyp should undergo surgical resection of that bowel segment is controversial. We examined the records of 83 patients with such polyps that were removed endoscopically between 1978 and 1981. After exclusion of 18 patients from the study ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)65198-2
更新日期：1986-02-01 00:00:00
abstract：:Cirrhosis and its disease-related complications are the 12th leading cause of mortality among U.S. adults and are the 5th leading cause of death for individuals aged 45 to 54 years. Hospitalization costs for disease-related complications are estimated at 18,000 dollars per episode of care, and 10% of admitted patients...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/80.11.1501
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:To assess the frequency and clinical implications of positive autoimmune serologies in patients with biopsy-confirmed idiopathic pulmonary fibrosis (IPF). PATIENTS AND METHODS:We reviewed the records of patients at our institution with biopsy-confirmed usual interstitial pneumonia (UIP) from January 1, 1995,...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2013.11.018
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVE:To describe the Mayo Clinic experience with emergency video telemedicine consultations for high-risk newborn deliveries. PATIENTS AND METHODS:From March 26, 2013, through December 31, 2015, the Division of Neonatal Medicine offered newborn telemedicine consultations to 6 health system sites. A wireless table...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2016.08.006
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:To investigate whether patients with traumatic brain injury (TBI) have an increased risk of stroke or poststroke mortality. PARTICIPANTS AND METHODS:Using Taiwan's National Health Insurance Research Database, we conducted a retrospective cohort study of 30,165 patients with new TBI and 120,660 persons withou...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2013.09.019
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To obtain pilot prospective data regarding the efficacy and tolerability of gabapentin for alleviating hot flashes. PATIENTS AND METHODS:This prospective single-arm clinical trial was conducted between July 26, 2001, and November 30, 2001. Patients underwent a baseline week and then 4 weeks of gabapentin tre...
journal_title：Mayo Clinic proceedings
pub_type： 临床试验,杂志文章
doi：10.4065/77.11.1159
更新日期：2002-11-01 00:00:00
abstract：OBJECTIVE:To measure carotid artery intima-media thickness (CIMT), a marker of subclinical atherosclerosis, in postmenopausal women with and without histories of preeclampsia and to synthesize these results with those from prior studies of CIMT performed 10 or more years after preeclamptic pregnancies. PATIENTS AND ME...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2017.05.030
更新日期：2017-09-01 00:00:00
abstract：:Forty cases of focal sclerosing glomerulonephropathy with nephrotic syndrome or proteinuria were studied retrospectively in regard to clinical presentation, response to steroid therapy and clinical course, and histopathology of the lesion. Morphologically there was a focal segmental and global sclerosis with subendot...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：:Rapid eye movement sleep behavior disorder (RBD) is diagnosed by a clinical history of dream enactment accompanied by polysomnographic rapid eye movement sleep atonia loss (rapid eye movement sleep without atonia). Rapid eye movement sleep behavior disorder is strongly associated with neurodegenerative disease, especi...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/j.mayocp.2017.09.007
更新日期：2017-11-01 00:00:00
