Comparison of analgesic requirements after liver transplantation and cholecystectomy.

Abstract:

:In a prospective study of 10 patients who underwent liver transplantation and 10 patients who underwent cholecystectomy, we analyzed the postoperative analgesic requirements and the resultant plasma morphine concentrations. Analgesia was more intense, with less medication, and the plasma morphine concentration was significantly lower in the liver transplant group than in the cholecystectomy group. This finding is most likely attributable to endogenous factors rather than to altered morphine pharmacokinetics.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Eisenach JC,Plevak DJ,Van Dyke RA,Southorn PA,Danielson DR,Krom RA,Nagorney DM,Rettke SR

doi

10.1016/s0025-6196(12)65257-4

subject

Has Abstract

pub_date

1989-03-01 00:00:00

pages

356-9

issue

3

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(12)65257-4

journal_volume

64

pub_type

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