Comparison of analgesic requirements after liver transplantation and cholecystectomy.


:In a prospective study of 10 patients who underwent liver transplantation and 10 patients who underwent cholecystectomy, we analyzed the postoperative analgesic requirements and the resultant plasma morphine concentrations. Analgesia was more intense, with less medication, and the plasma morphine concentration was significantly lower in the liver transplant group than in the cholecystectomy group. This finding is most likely attributable to endogenous factors rather than to altered morphine pharmacokinetics.


Mayo Clin Proc


Mayo Clinic proceedings


Eisenach JC,Plevak DJ,Van Dyke RA,Southorn PA,Danielson DR,Krom RA,Nagorney DM,Rettke SR




Has Abstract


1989-03-01 00:00:00














  • Barrett's esophagus occurring as a complication of scleroderma.

    abstract::Two patients had both scleroderma and a columnar epithelium-lined lower esophagus (Barrett esophagus). Features of Barrett's esophagus included high esophageal strictures in both patients and ulcer craters in the columnar area of one. Biopsy confirmed columnar epithelium in the lower esophagus of each patient. In thes...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Cameron AJ,Payne WS

    更新日期:1978-09-01 00:00:00

  • The necessity for clinical reasoning in the era of evidence-based medicine.

    abstract::Clinical decisions are increasingly driven by evidence-based recommendations of guideline groups, which aim to be based on the highest quality knowledge-randomized clinical trials (RCTs) and meta-analyses. Although RCTs provide the best assessment of the overall value of a therapy, high-quality evidence from RCTs is o...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Sniderman AD,LaChapelle KJ,Rachon NA,Furberg CD

    更新日期:2013-10-01 00:00:00

  • Long-term versus short-term treatment with recombinant interferon alfa-2a in patients with chronic hepatitis B: a prospective, randomized treatment trial.

    abstract::We conducted a prospective, randomized trial to study the efficacy and tolerance of long-term versus short-term treatment with recombinant interferon alfa-2a in patients with chronic hepatitis B. Ten patients were randomly assigned to a 6-month interferon regimen, and 10 patients were assigned to a 3-week interferon t...

    journal_title:Mayo Clinic proceedings

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Rakela J,Wood JR,Czaja AJ,O'Brien PC,Taswell HF,Bowyer BA,Lange SM,Anderson ML,Parent K

    更新日期:1990-10-01 00:00:00

  • Sequence of Splenectomy and Rituximab for the Treatment of Steroid-Refractory Immune Thrombocytopenia: Does It Matter?

    abstract:OBJECTIVE:To evaluate the impact of the sequence of treatment with rituximab and/or splenectomy on time to relapse for patients with steroid-refractory immune thrombocytopenia (ITP). PATIENTS AND METHODS:Patients 18 years or older with steroid-refractory immune thrombocytopenia who underwent treatment with splenectomy...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Hammond WA,Vishnu P,Rodriguez EM,Li Z,Dholaria B,Shreders AJ,Rivera CE

    更新日期:2019-11-01 00:00:00

  • Recent improvements in survival in primary systemic amyloidosis and the importance of an early mortality risk score.

    abstract:OBJECTIVE:To examine whether the outcome of patients with primary systemic amyloidosis (AL) has improved over time and to identify predictors of early mortality in patients with AL. PATIENTS AND METHODS:We studied 2 separate cohorts of patients. The first cohort, consisting of 1998 patients with AL seen at Mayo Clinic...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Kumar SK,Gertz MA,Lacy MQ,Dingli D,Hayman SR,Buadi FK,Short-Detweiler K,Zeldenrust SR,Leung N,Greipp PR,Lust JA,Russell SJ,Kyle RA,Rajkumar SV,Dispenzieri A

    更新日期:2011-01-01 00:00:00

  • Spasm in ectatic coronary arteries.

    abstract::Patients with ectatic coronary arteries often have occlusion of the affected arteries. Because ectatic arteries are considered to have medial damage, they are normally assumed to have little capacity to constrict; therefore, spasm has not been considered a factor in the occlusive process. In two patients who had diffu...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Bove AA,Vlietstra RE

    更新日期:1985-12-01 00:00:00

  • The impact of migraine and the effect of migraine treatment on workplace productivity in the United States and suggestions for future research.

    abstract::Evidence suggests that migraine is associated with decreased productivity. This article describes the results of a systematic literature review of peer-reviewed publications that measured the impact of migraine on workplace productivity in the United States and provides recommendations for future research. A MEDLINE s...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Burton WN,Landy SH,Downs KE,Runken MC

    更新日期:2009-05-01 00:00:00

  • Primarily resected meningiomas: outcome and prognostic factors in 581 Mayo Clinic patients, 1978 through 1988.

    abstract:OBJECTIVE:To establish prognostic factors for recurrence and outcome of surgical treatment, with or without postoperative radiation therapy, in patients with meningiomas. MATERIAL AND METHODS:From 1978 through 1988, 581 patients underwent initial resection of a previously untreated primary meningioma at Mayo Clinic Ro...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Stafford SL,Perry A,Suman VJ,Meyer FB,Scheithauer BW,Lohse CM,Shaw EG

    更新日期:1998-10-01 00:00:00

  • Causes and presenting features in 85 consecutive patients with hypersensitivity pneumonitis.

    abstract:OBJECTIVE:To assess the current spectrum of causes and clinical features associated with hypersensitivity pneumonitis (HP). PATIENTS AND METHODS:We studied consecutive patients with HP diagnosed at the Mayo Clinic in Rochester, Minn, from January 1, 1997, through December 31, 2002. Diagnostic criteria for HP included ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Hanak V,Golbin JM,Ryu JH

    更新日期:2007-07-01 00:00:00

  • Effect of intraoperative anesthetic events on postoperative patient satisfaction.

    abstract:OBJECTIVE:To assess overall perioperative and anesthetic care-specific patient satisfaction. DESIGN:We mailed questionnaires postoperatively to three groups of surgical patients (those who underwent anesthesia without complications, those who experienced airway management difficulties, and those who had cardiovascular...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Brown DL,Warner ME,Schroeder DR,Offord KP

    更新日期:1997-01-01 00:00:00

  • REM Sleep Behavior Disorder: Diagnosis, Clinical Implications, and Future Directions.

    abstract::Rapid eye movement sleep behavior disorder (RBD) is diagnosed by a clinical history of dream enactment accompanied by polysomnographic rapid eye movement sleep atonia loss (rapid eye movement sleep without atonia). Rapid eye movement sleep behavior disorder is strongly associated with neurodegenerative disease, especi...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: St Louis EK,Boeve BF

    更新日期:2017-11-01 00:00:00

  • Diagnosis of obesity by primary care physicians and impact on obesity management.

    abstract:OBJECTIVE:To evaluate whether primary care physicians document obesity as a diagnosis and formulate a management plan. PATIENTS AND METHODS:The Mayo Clinic primary care database was used to identify general medical examinations performed from November 1, 2004, to October 31, 2005, in a primary care clinic for obese pa...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Bardia A,Holtan SG,Slezak JM,Thompson WG

    更新日期:2007-08-01 00:00:00

  • Carotid Artery Intima-Media Thickness and Subclinical Atherosclerosis in Women With Remote Histories of Preeclampsia: Results From a Rochester Epidemiology Project-Based Study and Meta-analysis.

    abstract:OBJECTIVE:To measure carotid artery intima-media thickness (CIMT), a marker of subclinical atherosclerosis, in postmenopausal women with and without histories of preeclampsia and to synthesize these results with those from prior studies of CIMT performed 10 or more years after preeclamptic pregnancies. PATIENTS AND ME...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Garovic VD,Milic NM,Weissgerber TL,Mielke MM,Bailey KR,Lahr B,Jayachandran M,White WM,Hodis HN,Miller VM

    更新日期:2017-09-01 00:00:00

  • Focal sclerosing glomerulonephropathy: a clinicopathologic study.

    abstract::Forty cases of focal sclerosing glomerulonephropathy with nephrotic syndrome or proteinuria were studied retrospectively in regard to clinical presentation, response to steroid therapy and clinical course, and histopathology of the lesion. Morphologically there was a focal segmental and global sclerosis with subendot...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Velosa JA,Donadio JV Jr,Holley KE

    更新日期:1975-03-01 00:00:00

  • Cardiac Rehabilitation for Women: A Systematic Review of Barriers and Solutions.

    abstract::Cardiac rehabilitation (CR) services improve various clinical outcomes in patients with cardiovascular disease, but such services are underutilized, particularly in women. The aim of this study was to identify evidence-based barriers and solutions for CR participation in women. A literature search was carried out usin...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Supervía M,Medina-Inojosa JR,Yeung C,Lopez-Jimenez F,Squires RW,Pérez-Terzic CM,Brewer LC,Leth SE,Thomas RJ

    更新日期:2017-03-13 00:00:00

  • The adrenergic nervous system and hypertension state of the art.

    abstract::This discussion concerns an overview of our considerations of the adrenergic nervous system with respect to those areas of the nervous system that provide direct sensory input to the brain in control of arterial pressure; those brain centers that also participate in regulating arterial pressure; certain neurohumoral c...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Frohlich ED

    更新日期:1977-06-01 00:00:00

  • A contemporary conceptual model of hypochondriasis.

    abstract::Hypochondriasis (HC), which involves preoccupation with the fear of having a serious illness despite appropriate medical examination, is often encountered in medical settings. The most conspicuous feature of this disorder is seeking excessive reassurance from physicians, medical references, or self-inspection; however...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Abramowitz JS,Schwartz SA,Whiteside SP

    更新日期:2002-12-01 00:00:00

  • Transesophageal atrial pacing in the Wolff-Parkinson-White syndrome.

    abstract::In a patient with Wolff-Parkinson-White syndrome, protracted, disabling tachycardia occurred because of low left lateral accessory pathway refractoriness and rapid retrograde conduction, most likely by a septal pathway. Conventional medications, including intravenously administered lidocaine and procainamide, were ine...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Hartzler GO,Maoloney JD

    更新日期:1977-09-01 00:00:00

  • Electron beam computed tomography and coronary artery disease: scanning for coronary artery calcification.

    abstract:OBJECTIVE:To review the association of coronary artery calcification with coronary atherosclerosis and its potential clinical application as detected on electron beam computed tomography (EBCT). DESIGN:A literature review of coronary artery calcification, coronary artery disease, and EBCT is presented, and clinical ap...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Rumberger JA,Sheedy PF 2nd,Breen JF,Fitzpatrick LA,Schwartz RS

    更新日期:1996-04-01 00:00:00

  • Dehydroepiandrosterone replacement therapy in hypoadrenal women: protein anabolism and skeletal muscle function.

    abstract:OBJECTIVE:To determine whether dehydroepiandrosterone (DHEA) replacement therapy in hypoadrenal women improves performance, muscle protein accretion, and mitochondrial functions. PARTICIPANTS AND METHODS:Thirty-three hypoadrenal women were enrolled in the study from May 1, 2002, through May 31, 2003. Twenty-eight comp...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,随机对照试验


    authors: Dhatariya KK,Greenlund LJ,Bigelow ML,Thapa P,Oberg AL,Ford GC,Schimke JM,Nair KS

    更新日期:2008-11-01 00:00:00

  • Safety, diagnostic yield, and therapeutic implications of flexible bronchoscopy in patients with febrile neutropenia and pulmonary infiltrates.

    abstract:OBJECTIVE:To evaluate the safety, diagnostic yield, and therapeutic implications of flexible bronchoscopy with bronchoalveolar lavage (BAL) and transbronchial biopsy in patients with febrile neutropenia and pulmonary infiltrates. PATIENTS AND METHODS:We retrospectively reviewed the medical records of all patients with...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Peikert T,Rana S,Edell ES

    更新日期:2005-11-01 00:00:00

  • Carotid sinus hypersensitivity and syncope.

    abstract::The patient with a hypersensitive carotid sinus reflex and syncope may pose special challenges in evaluation and treatment. Specifically, although the finding of carotid sinus hypersensitivity may indeed indicate an exaggerated vagal tone that causes syncope, it may also be a chance association in a patient with synco...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Sugrue DD,Wood DL,McGoon MD

    更新日期:1984-09-01 00:00:00

  • Exercise Capacity and Atrial Fibrillation Risk in Veterans: A Cohort Study.

    abstract:OBJECTIVE:To assess the association between exercise capacity and the risk of developing atrial fibrillation (AF). PATIENTS AND METHODS:A symptom-limited exercise tolerance test was conducted to assess exercise capacity in 5962 veterans (mean age, 56.8±11.0 years) from the Veterans Affairs Medical Center, Washington, ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Faselis C,Kokkinos P,Tsimploulis A,Pittaras A,Myers J,Lavie CJ,Kyritsi F,Lovic D,Karasik P,Moore H

    更新日期:2016-05-01 00:00:00

  • Effectiveness of sumatriptan in reducing productivity loss due to migraine: results of a randomized, double-blind, placebo-controlled clinical trial.

    abstract:OBJECTIVE:To determine the effect of sumatriptan on migraine-related workplace productivity loss. PATIENTS AND METHODS:In this randomized, double-blind, placebo-controlled, parallel-group trial, adult migraineurs self-injected 6 mg of sumatriptan or matching placebo to treat a moderate or severe migraine within the fi...

    journal_title:Mayo Clinic proceedings

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Schulman EA,Cady RK,Henry D,Batenhorst AS,Putnam DG,Watson CB,O'Quinn SO

    更新日期:2000-08-01 00:00:00

  • Hypersensitivity pneumonitis associated with Mycobacterium avium complex and hot tub use.

    abstract::Many diseases, mainly infectious and inhalational, have been associated with the use of hot tubs. "Hot tub lung" is a recently described disease entity associated with Mycobacterium avium complex (MAC) and is thought to be either an infection or a hypersensitivity pneumonitis. We describe 2 patients with progressively...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Rickman OB,Ryu JH,Fidler ME,Kalra S

    更新日期:2002-11-01 00:00:00

  • Sympathetic neural mechanisms in human cardiovascular health and disease.

    abstract::The sympathetic nervous system plays a key role in regulating arterial blood pressure in humans. This review provides an overview of sympathetic neural control of the circulation and discusses the changes that occur in various disease states, including hypertension, heart failure, and obstructive sleep apnea. It focus...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Charkoudian N,Rabbitts JA

    更新日期:2009-09-01 00:00:00

  • Effect on hemoglobin A1 of rapid normalization of glycemia with an artificial endocrine pancreas.

    abstract::Six insulin-requiring chronically hyperglycemic diabetic patients underwent glucose control for 72 hours with an artificial endocrine pancreas, the Biostator Glucose Controller. Euglycemia was within 4 hours and was maintained (110 leads to 2 mg/dl) thereafter. The concentration of hemoglobin A (HbA) was elevated, at ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Service FJ,Fairbanks VF,Rizza RA

    更新日期:1981-06-01 00:00:00

  • Cheaper, simpler, and better: tips for treating seniors with Parkinson disease.

    abstract::Treatment of seniors with Parkinson disease is within the domain of primary care physicians and internists. A good working knowledge of carbidopa/levodopa principles should allow excellent care of most patients, at least during the early years of the disease. Even later, when levodopa responses become more complicated...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Ahlskog JE

    更新日期:2011-12-01 00:00:00

  • Cutaneous malignant melanoma.

    abstract::Skin cancer has become the most common neoplasm in the United States. With early diagnosis and appropriate management, most skin cancers have an overall 5-year survival rate of 95%. Cutaneous malignant melanoma (CMM), however, has a significantly higher morbidity and mortality, resulting in 65% of all skin cancer deat...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Cummins DL,Cummins JM,Pantle H,Silverman MA,Leonard AL,Chanmugam A

    更新日期:2006-04-01 00:00:00

  • Effect of β-blockers and other antihypertensive drugs on the risk of melanoma recurrence and death.

    abstract:OBJECTIVE:To verify preliminary studies on patients with melanoma exposed to β-blockers that suggested a reduced risk of disease recurrence and death. PATIENTS AND METHODS:Data were obtained from all consecutive patients diagnosed as having melanoma between January 1, 1993, and December 31, 2009, at the Department of ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: De Giorgi V,Gandini S,Grazzini M,Benemei S,Marchionni N,Geppetti P

    更新日期:2013-11-01 00:00:00