Abstract：
BACKGROUND:Pontine tumors carry the worst prognosis of all brain tumors. In most cases, the diagnosis is based solely on MR imaging, without biopsy. OBJECTIVE:To describe the MR findings of pontine tumors at diagnosis and during follow-up and correlate those with prognosis and to assess the value of MR imaging in patient management compared to clinical evaluation. MATERIALS AND METHODS:Ninety-one MR scans of 15 children with diffuse pontine tumors were reviewed at diagnosis and during follow-up. The parameters analyzed were as follows: tumor extent, area, and volume; encasement of the basilar artery; presence of exophytic component; necrosis; cysts; hydrocephalus; and intensity and enhancement. Findings were correlated to length of progression-free and overall survival. Trends of amelioration or worsening on imaging were compared with the clinical findings. RESULTS:Median length of progression-free survival was 10 months, and median survival was 20 months. Only hydrocephalus at presentation was associated with shorter progression-free survival (P=0.02). On the last examination of each patient, the craniocaudal diameter was significantly greater than at diagnosis (P=0.03). The concordance between the imaging and the clinical findings was good. CONCLUSION:MR is the mainstay for the diagnosis and management of pontine tumors. Cranial growth seems to be an ominous sign. However, the prognostic value of MR is limited. MR findings correlate well with the clinical examination.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Kornreich L,Schwarz M,Karmazyn B,Cohen IJ,Shuper A,Michovitz S,Yaniv I,Fenig E,Horev Gdoi
10.1007/s00247-005-1502-ykeywords:
subject
Has Abstractpub_date
2005-09-01 00:00:00pages
872-9issue
9eissn
0301-0449issn
1432-1998journal_volume
35pub_type
杂志文章,评审abstract：:Shaken-baby syndrome (SBS) is a type of child abuse caused by violent shaking of an infant, with or without impact, and characterized by subdural hematomas, retinal hemorrhages, and occult bone fractures. Parenchymal brain lesions in SBS may be missed or underestimated on CT scans, but can be detected at an earlier st...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-003-1025-3
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journal_title：Pediatric radiology
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doi：10.1007/s002470050206
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journal_title：Pediatric radiology
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journal_title：Pediatric radiology
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doi：10.1007/s00247-008-1003-x
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abstract：:A seven month old female having a single arterial trunk arising from the aortic arch is presented. The baby also had severe coarctation of the aorta and a patent ductus arteriosus. This anomaly cannot be explained by Edwards' embryonic double aortic arch model. However, it can be explained by persistence of the fifth ...
journal_title：Pediatric radiology
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journal_title：Pediatric radiology
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journal_title：Pediatric radiology
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journal_title：Pediatric radiology
pub_type： 杂志文章,评审
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journal_title：Pediatric radiology
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journal_title：Pediatric radiology
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更新日期：1995-01-01 00:00:00
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journal_title：Pediatric radiology
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journal_title：Pediatric radiology
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更新日期：1984-01-01 00:00:00
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journal_title：Pediatric radiology
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doi：10.1007/BF02343430
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journal_title：Pediatric radiology
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更新日期：2014-10-01 00:00:00
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journal_title：Pediatric radiology
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journal_title：Pediatric radiology
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journal_title：Pediatric radiology
pub_type： 杂志文章,已发布勘误
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更新日期：2019-03-01 00:00:00
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journal_title：Pediatric radiology
pub_type： 杂志文章,评审
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journal_title：Pediatric radiology
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更新日期：2018-09-01 00:00:00
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journal_title：Pediatric radiology
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更新日期：1999-09-01 00:00:00
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journal_title：Pediatric radiology
pub_type： 杂志文章
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更新日期：1986-01-01 00:00:00
