Abstract:
:In pediatric oncology, therapeutic decisions are made based on tumor response to chemotherapeutic agents. Sequential measurement of tumor bulk and its percent change on therapy must be accurately assessed. Will 3-dimensional (3-D) volumetric determination improve our ability to assess tumor response to therapy? Forty-five CT scans of pediatric patients with unresectable thoracic or abdominal neoplasia were assessed for tumor bulk by the standard "2-dimensional (2-D)" volume formula (cross-sectional area x length) and by 3-D volumetric analysis. Thirty-two examinations were performed in follow-up, and percent change in tumor size was calculated. The 2-D volume calculation overestimated tumor volume by more than 50% on all but two examinations when the 2-D volume was compared with the 3-D volume. In 28% of follow-up examinations, the 2-D calculation of percent change differed by more than 10% from the 3-D volume. Fifteen percent differed by over 25%. This changed the response category of one patient from "no response" to "partial response". 3-D volumetric analysis, easily performed by a trained technologist, will give more accurate assessment of the actual tumor bulk and its subsequent changes in size in response to therapy.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Eggli KD,Close P,Dillon PW,Umlauf M,Hopper KDdoi
10.1007/BF02020828subject
Has Abstractpub_date
1995-01-01 00:00:00pages
1-6issue
1eissn
0301-0449issn
1432-1998journal_volume
25pub_type
杂志文章abstract::Many pitfalls result from the limited ability of Doppler instruments to record low flow velocities. These include a misleading resistance or pulsatility index due to diastolic cut-off and taking no signal to equal no flow assuming that no signal means no flow. Comparison of actual flow velocities as measured in an in-...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02013161
更新日期:1990-01-01 00:00:00
abstract::We report a healthy, asymptomatic 15-year-old girl with a meandering right pulmonary vein draining to the left atrium. A meandering pulmonary vein may or may not be associated with the scimitar syndrome. The differential diagnosis with the scimitar syndrome and other forms of scimitar variants is discussed. ...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s002470050651
更新日期:1999-08-01 00:00:00
abstract::We report a rare case of atypical teratoid/rhabdoid tumor that presented with imaging findings similar to those of optic pathway glioma. The diagnosis of atypical teratoid/rhabdoid tumor was determined following surgical resection of the tumor by collective histologic and immunohistochemical staining, and cytogenetic ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-008-0923-9
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Subglottic haemangioma causes progressive and life-threatening stridor, typically manifesting at age 2-3 months. Standard diagnosis is by laryngoscopy. Larynx sonography is rarely used but allows assessment of the presence and extension of a mass that impinges on the subglottic airway. The additional use of ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-011-2213-1
更新日期:2011-11-01 00:00:00
abstract::A 10-year old, mentally and physically normally developed girl complained of back pain following an accident. Radiological findings revealed an inhomogeneous, coarse osteosclerosis along the endplates and posterior parts of the ovoid shaped vertebral bodies, in the proximal and distal femora-, proximal humeri and tibi...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02387669
更新日期:1989-01-01 00:00:00
abstract::Castleman's disease is a benign lymphoproliferative disorder characterised by enlarged hyperplastic lymph nodes. It is rare in children and usually presents as localised disease. Subpectoral involvement has not been previously described in multicentric Castleman's disease in children. We present the CT, US and Doppler...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-003-0947-0
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:Percutaneous retrograde gastrostomy has a high success rate, low morbidity, and can be performed under different levels of sedation or local anesthesia in children. Despite its favourable safety profile, major complications can occur. Few studies have examined peritonitis following percutaneous retrograde ga...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-016-3628-5
更新日期:2016-09-01 00:00:00
abstract::A 6-week-old girl presented with bronchiolitis secondary to respiratory syncytial virus. Eight days after admission she developed a Staphylococcus aureus infection at a previous intravenous cannula site. Despite antibiotic therapy this led to an anterior mediastinal staphylococcal abscess, which was drained surgically...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::Purpose. To determine the incidence of neurologic complications of cerebral angiography in children with moyamoya syndrome (MMS) as compared to children without MMS. Materials and methods. One-hundred-ninety consecutive cerebral angiograms obtained in 152 children were evaluated. Sixty of these angiograms were obtaine...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050474
更新日期:1998-11-01 00:00:00
abstract:BACKGROUND:Dose reduction by combined tube current modulation has not been evaluated in pediatric low-dose CT. OBJECTIVE:This study was performed to evaluate tube current reduction in non-ECG-gated heart CT angiography in children by combined tube current modulation, and to assess the effects of body weight, age, sex,...
journal_title:Pediatric radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00247-005-0105-y
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:Dual-energy absorptiometry (DXA) is the current reference standard for assessing pediatric osteoporosis; however due to its areal nature, it has limitations. Thus, quantitative ultrasound (QUS), a modality free of ionizing radiation, has been proposed as a potential surrogate for DXA. OBJECTIVE:To semi-quan...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-014-3041-x
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Assessment tools for early cystic fibrosis (CF) lung disease are limited. Detecting early pulmonary disease is crucial to increasing life expectancy by starting interventions to slow the progression of the pulmonary disease with the many treatment options available. OBJECTIVE:To compare the utility of lung ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-020-04638-9
更新日期:2020-06-01 00:00:00
abstract::Ferumoxytol is an ultra-small superparamagnetic iron oxide (USPIO) particle that is FDA-approved for parenteral treatment of iron deficiency anemia in adults with chronic kidney disease. Because of the association between gadolinium-based contrast agents and nephrogenic systemic fibrosis in patients with severe chroni...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-016-3605-z
更新日期:2016-08-01 00:00:00
abstract::Sonographic studies on 52 children with suspected peripheral vascular disease examined between January 1988 and December 1989 were retrospectively reviewed. A technique for examining the jugular, subclavian veins, and superior vena cava (SVC) was developed and is described. The technique for examining the extremities ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02011718
更新日期:1991-01-01 00:00:00
abstract::Part 1 of this series of two articles describes conventional and advanced MRI techniques that are useful for evaluating brainstem pathologies. In addition, it provides a review of the embryology, normal progression of myelination, and clinically and radiologically salient imaging anatomy of the normal brainstem. Final...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-020-04954-0
更新日期:2021-02-01 00:00:00
abstract::Gonadal dysgenesis and coarctation of the aorta were found in four patients to be associated with premature sternal fusion but possible etiologic relationship to shield chest deformity in suggested. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02386775
更新日期:1985-01-01 00:00:00
abstract::Cranial sonography plays an important role in the initial evaluation of infants with suspected bacterial meningitis and in monitoring for complications of the disease. Echogenic widening of the brain sulci, meningeal thickening and hyperemia suggest the diagnosis in an at-risk population. Sonography can identify the p...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-007-0538-6
更新日期:2008-02-01 00:00:00
abstract::Intussusception in the pediatric patient may have a varied clinical presentation depending on its location, presence of lead point, intermittent occurrence, or underlying systemic disease. Computed tomography (CT) may be used at times in the evaluation of children with complicated presentations. The purpose of this in...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01403699
更新日期:1996-01-01 00:00:00
abstract::As utilization of MRI for clinically suspected pediatric appendicitis becomes more common, there will be increased focus on case interpretation. The purpose of this pictorial essay is to share our institution's case interpretation experience. MRI findings of appendicitis include appendicoliths, tip appendicitis, intra...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2866-z
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Conventional MRI sequences are often affected in neuropediatric imaging by unavoidable movements. Therefore, children younger than 6 years usually have to be examined under sedation/anesthesia. A new real-time MRI technique with automatic slice advancement allows for motion-robust T2-weighted volume coverage...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-020-04771-5
更新日期:2020-11-01 00:00:00
abstract::Up to now, the presence of elevated intracranial pressure (ICP) in acute neurological disorders is suspected by clinical and neuroimaging findings, but its verification depends on invasive techniques. Based on our experimental findings of rapid dilatation of human optic nerve sheaths (ONS), we investigated whether thi...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01383384
更新日期:1996-10-01 00:00:00
abstract::In 30 children with renal allografts the diagnostic validity of pulsed Doppler (PD) versus colour coded Doppler (CD) sonography was assessed prospectively. 46 PD examinations were performed calculating the resistive index (RI) in the segmental arteries in comparison to 46 CD scans, where renal blood flow throughout th...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012486
更新日期:1992-01-01 00:00:00
abstract::A case of intramural esophageal pseudodiverticulosis in a five-year-old with a 16-year follow up is presented. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF00971777
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Unusual acute symptomatic and reversible early-delayed leukoencephalopathy has been reported to be induced by methotrexate (MTX). OBJECTIVE:We aimed to identify the occurrence of such atypical MTX neurotoxicity in children and document its MR presentation. MATERIALS AND METHODS:We retrospectively reviewed ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-005-0015-z
更新日期:2006-03-01 00:00:00
abstract::We report our observations made by conventional radiography, ultrasound, computerized tomography (CT), and magnetic resonance imaging (MRI) on a 3 1/2-year-old girl with Gaucher's disease. The interest of the case consists in the exceptional lungs involvement, the demonstration by MRI of the bone marrow involvement an...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02011620
更新日期:1992-01-01 00:00:00
abstract::Ureteral valves are an uncommon cause of upper urinary tract obstruction. The majority of cases are discovered only at surgery or autopsy. We report a case diagnosed by antegrade pyelography under sonographic guidance and we review the literature. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388420
更新日期:1988-01-01 00:00:00
abstract::A calcified thrombus in the inferior vena cava of infants and children may be imaged by computed tomography. The precise location of the calcification within the inferior vena cava may be confirmed by computed tomographic scanning during injection of intravenous contrast material. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01001751
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The neurocentral synchondrosis (NCS) is a cartilaginous growth plate that since the early 1900s has been implicated as a potential cause of adolescent idiopathic scoliosis (AIS). Previous studies have focused only on the closure age without characterizing normal NCS development. Using MRI, the...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-002-0771-y
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:New developments in processing of digital radiographs (DR), including multi-frequency processing (MFP), allow optimization of image quality and radiation dose. This is particularly promising in children as they are believed to be more sensitive to ionizing radiation than adults. OBJECTIVE:To examine whether...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-012-2385-3
更新日期:2012-09-01 00:00:00
abstract::Intramuscular myxoma (IM) is a true mesenchymal benign tumour which is rare in both adults and children. In children, it most commonly affects the heart, mandible or maxilla. We report a 5-year-old child with IM presenting as a posterolateral neck mass and review the literature. IM, although very rare, should be inclu...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-001-0603-5
更新日期:2002-02-01 00:00:00