Cocaine- and amphetamine-regulated transcript in the nucleus accumbens participates in the regulation of feeding behavior in rats.

abstract：:Sensory experience has a profound effect on neocortical neurons. Passive stimulation of whiskers or sensory deprivation from whiskers can induce long-lasting changes in neuronal responses or modify the receptive field in adult animals. We recorded barrel cortical neurons in urethane-anesthetized rats in layers 2/3 or ...

journal_title：Neuroscience

authors： Barros-Zulaica N,Castejon C,Nuñez A

更新日期：2014-12-05 00:00:00

abstract：:Immunohistochemistry for vanilloid receptor 1-like receptor (VRL-1), a candidate transducer for high-threshold noxious heat, was performed on rat trigeminal primary sensory neurons. The immunoreactivity was detected in 14% of the trigeminal ganglion cell bodies, while the neurons in the mesencephalic trigeminal tract ...

journal_title：Neuroscience

authors： Ichikawa H,Sugimoto T

更新日期：2000-01-01 00:00:00

abstract：:Exercise induces neuroplasticity in descending motor pathways facilitating motor learning, and as such it could be utilized as an intervention in neurorehabilitation, for example when re-learning motor skills after stroke. To date, however, the neurophysiological and molecular mechanisms underlying exercise-induced ne...

journal_title：Neuroscience

authors： Nicolini C,Michalski B,Toepp SL,Turco CV,D'Hoine T,Harasym D,Gibala MJ,Fahnestock M,Nelson AJ

更新日期：2020-06-15 00:00:00

abstract：:This study aimed to investigate the effects of regular treadmill exercise on nerve growth factor (NGF) expression, the improvement of cognitive function in the hippocampus of diabetic rats, and to understand the molecular mechanisms through which the relevant signaling factors act. We investigated the effects of regul...

journal_title：Neuroscience

authors： Chae CH,Jung SL,An SH,Park BY,Wang SW,Cho IH,Cho JY,Kim HT

更新日期：2009-12-29 00:00:00

abstract：:Many epidemiological studies support the notion that people who drink alcohol also smoke cigarettes and vice versa thereby suggesting a possible functional interaction between these two most widely used psychoactive substances. We have earlier demonstrated that direct intracerebellar (ICB) microinfusion of nicotine do...

journal_title：Neuroscience

authors： Taslim N,Al-Rejaie S,Saeed Dar M

更新日期：2008-11-11 00:00:00

abstract：:Curiosity surrounding the physiological relevance of neural insulin signaling has gradually developed since the discovery that nervous tissue contains both the hormone and its receptor. Similar to other receptor tyrosine kinases, ligand interaction with the insulin receptor (IR) activates a variety of intracellular si...

journal_title：Neuroscience

authors： Mielke JG,Taghibiglou C,Wang YT

更新日期：2006-11-17 00:00:00

abstract：:Histochemistry for cytochrome oxidase reveals a vibrissa-related pattern in trigeminal nucleus principalis, subnucleus interpolaris, and the magnocellular portion of subnucleus caudalis. This pattern is apparent in late fetal animals and is disrupted by transection of the infraorbital nerve on the day of birth. We rec...

journal_title：Neuroscience

authors： Chiaia NL,Bennett-Clarke CA,Rhoades RW

更新日期：1992-07-01 00:00:00

abstract：:Pain is processed in a large neural network that partially overlaps structures involved in emotion processing. Despite the fact that pain and emotion are known to share neural regions and interact in numerous clinical conditions, relatively little is known about the interaction of pain and emotion at the neural level....

journal_title：Neuroscience

authors： Orenius TI,Raij TT,Nuortimo A,Näätänen P,Lipsanen J,Karlsson H

更新日期：2017-05-04 00:00:00

abstract：:A variety of neurological diseases are characterized by disturbances of the blood-brain barrier (BBB) and its transporters. We recently introduced fibroblast growth factor treated cortical organotypic slice cultures of mice as a model for in vitro studies of the blood-brain barrier and have now further characterized t...

journal_title：Neuroscience

authors： Camenzind RS,Chip S,Gutmann H,Kapfhammer JP,Nitsch C,Bendfeldt K

更新日期：2010-09-29 00:00:00

abstract：:Seizures produced by pilocarpine given i.p. to rats provide an animal model for studying the initiation, spread and generalisation of convulsive activity within the forebrain. Pilocarpine, 380 mg/kg, produces a sequence of behavioural and electroencephalographic alterations indicative of motor limbic seizures and stat...

journal_title：Neuroscience

authors： Turski L,Cavalheiro EA,Turski WA,Meldrum BS

更新日期：1986-05-01 00:00:00

abstract：:Excessive inflammatory response produced after cardiac arrest and cardiopulmonary resuscitation (CA/CPR) is one of major causes of cerebral injury. High mobility group box 1 (HMGB1) is a pro-inflammatory cytokine and its role in brain injury after CA/CPR is unclear. Herein we investigated whether blocking HMGB1 signal...

journal_title：Neuroscience

authors： Shi X,Li M,Huang K,Zhou S,Hu Y,Pan S,Gu Y

更新日期：2017-09-30 00:00:00

abstract：:The localization of GABA and parvalbumin was studied in the developing cerebellum of human fetuses from 16 to 28 weeks of gestation. The avidin-biotin complex immunohistochemical method combined with silver staining were used to reveal the presence of GABA- and parvalbumin-positive neurons and nerve fibres. As early a...

journal_title：Neuroscience

authors： Yu MC,Cho E,Luo CB,Li WW,Shen WZ,Yew DT

更新日期：1996-01-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β (TGF-β) superfamily. BMPs, such as BMP2 and BMP4, exert its biological functions by interacting with membrane bound receptors belonging to the serine/threonine kinase family including bone morphogenetic protein receptor I (BMPRIA, BMPRI...

journal_title：Neuroscience

authors： Miyagi M,Mikawa S,Sato T,Hasegawa T,Kobayashi S,Matsuyama Y,Sato K

更新日期：2012-02-17 00:00:00

abstract：:Neurons in the superior paraolivary nucleus (SPON) of the rat respond to the offset of pure tones with a brief burst of spikes. Medial nucleus of the trapezoid body (MNTB) neurons, which inhibit the SPON, produce a sustained pure tone response followed by an offset response characterized by a period of suppressed spon...

journal_title：Neuroscience

authors： Kadner A,Berrebi AS

更新日期：2008-02-06 00:00:00

abstract：:The effect of systemic administration of domoic acid, a potent structural analogue of kainic acid, on the mouse hippocampus has been studied using light and electron microscopic techniques. Intraperitoneal injections of either domoic acid (4 mg/kg) or kainic acid (32 mg/kg) produced a series of behavioural changes inc...

journal_title：Neuroscience

authors： Strain SM,Tasker RA

更新日期：1991-01-01 00:00:00

abstract：:The amyloid beta precursor protein can exist as both a membrane-bound and a secreted protein, with the former having the potential to generate the amyloid beta peptide present in the neuritic plaques which are characteristic of Alzheimer's disease. In this study, we have used a clone of the AtT20 mouse pituitary cell ...

journal_title：Neuroscience

authors： McFarlane I,Georgopoulou N,Coughlan CM,Gillian AM,Breen KC

更新日期：1999-04-01 00:00:00

abstract：:The axonal transport of the molecular forms of acetylcholinesterase was investigated in regenerating facial nerves of guinea-pig and rat. Four forms were separated by velocity sedimentation corresponding to 16S (A12), 10S (G4), 6S (G2) and 4S (G1) acetylcholinesterase. They displayed species-specific changes, which ar...

journal_title：Neuroscience

authors： Engel AK,Tetzlaff W,Kreutzberg GW

更新日期：1988-02-01 00:00:00

abstract：:Nucleus raphe magnus contains a large population of raphe-spinal serotonergic neurons that are thought to be involved in descending control of pain transmission and the modulation of opioid analgesia. Intracellular recordings were made from nucleus raphe magnus neurons in the slice preparation. Cells were divided into...

journal_title：Neuroscience

authors： Pan ZZ,Wessendorf MW,Williams JT

更新日期：1993-05-01 00:00:00

abstract：:Our current knowledge of the sites of action of the centrally-acting antihypertensive drug clonidine is based almost entirely on experiments in anesthetized animals. The aim of this study was to determine, in conscious rabbits, the sites of action in the brainstem of systemically administered clonidine, as well as its...

journal_title：Neuroscience

authors： Li YW,Dampney RA

更新日期：1995-05-01 00:00:00

abstract：:The adverse consequences of early-life sleep deprivation on mental health are well recognized, yet many aspects remain unknown, therefore, animal studies can offer useful insights. Male Sprague-Dawley rats at postnatal day (PND) 19 were subjected to sleep deprivation (SD) for 14 days (6-8 hours/day). Control (CON) rat...

journal_title：Neuroscience

authors： Atrooz F,Liu H,Kochi C,Salim S

更新日期：2019-05-15 00:00:00

abstract：:The effect of transitory blockage of substantia nigra pars compacta glutamatergic inputs by intracranial injections of kynurenic acid were evaluated in two monkey treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The MPTP protocol was designed to mimic the gradual evolution of human Parkinson's disease...

journal_title：Neuroscience

authors： Bezard E,Boraud T,Bioulac B,Gross CE

更新日期：1997-11-01 00:00:00

abstract：:Sensory processing disturbances, as measured in the P50/sensory gating paradigm, have been linked to aberrant auditory information processing and sensory overload in schizophrenic patients. In this paradigm, the response to the second of paired-click stimuli is attenuated by an inhibitory effect of the first stimulus....

journal_title：Neuroscience

authors： de Bruin NM,Ellenbroek BA,van Luijtelaar EL,Cools AR,Stevens KE

更新日期：2001-01-01 00:00:00

abstract：:Electrical stimulation of the distal stump of cut peripheral nerves is a commonly accepted way to evoke neurogenic inflammation. Nevertheless, the modulatory effect of biogenic amines and vasoactive peptides released from efferent fibres can be excluded only if the dorsal roots are stimulated. The present study was fo...

journal_title：Neuroscience

authors： Pintér E,Szolcsányi J

更新日期：1995-09-01 00:00:00

abstract：:4-Aminopyridine (4-AP) is suggested to improve symptomatology of spinal injury patients because it may facilitate neuromuscular transmission, spinal impulse flow and the operation of the locomotor central pattern generator (CPG). Since 4-AP can also induce repetitive discharges from dorsal root afferents, this phenome...

journal_title：Neuroscience

authors： Taccola G,Nistri A

更新日期：2005-01-01 00:00:00

abstract：:I.v. injection of secretin activates neurons in brain areas controlling autonomic function and emotion. Peripheral administration of secretin inhibits gastric functions through a central mechanism that is mediated by vagal dependent pathways. We investigated whether the vagus nerve is involved in i.p. injection of sec...

journal_title：Neuroscience

authors： Yang H,Wang L,Wu SV,Tay J,Goulet M,Boismenu R,Czimmer J,Wang Y,Wu S,Ao Y,Taché Y

更新日期：2004-01-01 00:00:00

abstract：:Stress has long been associated with the development of neuropsychiatric and neurological disorders. The effects of stress vary depending upon the age during which the stress is incurred, the duration and severity of the stressor, and can further be influenced by levels of circulating gonadal hormones. To date, the ma...

journal_title：Neuroscience

authors： Bath KG,Schilit A,Lee FS

更新日期：2013-06-03 00:00:00

abstract：:The response to iontophoretic application of acetylcholine in the mouse neuroblastoma cell line N1E-115 was composed of three phases. The initial fast depolarizing phase was blocked by 10 microM d-tubocurarine, but not by 0.1 microM atropine. This phase was followed by a transient hyperpolarization which in turn was f...

journal_title：Neuroscience

authors： Kato E,Anwyl R,Quandt FN,Narahashi T

更新日期：1983-03-01 00:00:00

abstract：:Although many workers have appreciated the striking cytologic and neurochemical similarities of neostriatum, accumbens and olfactory tubercle, a compelling case for regarding these areas as territories in a striatal complex awaited the arguments made by Heimer and his colleagues based on their investigations of connec...

journal_title：Neuroscience

authors： Zahm DS,Brog JS

更新日期：1992-10-01 00:00:00

abstract：:The effects of two benzodiazepines, diazepam and triazolam, on long-term potentiation were tested in slices of hippocampus and piriform cortex. The drugs had little influence on baseline synaptic responses but both were very effective in blocking LTP elicited by theta pattern stimulation. The effects were fully revers...

journal_title：Neuroscience

authors： del Cerro S,Jung M,Lynch G

更新日期：1992-07-01 00:00:00

abstract：:Oxytocin and vasopressin binding sites were localized and characterized by quantitative autoradiography on consecutive sections of Long-Evans rat forebrains and pituitary glands, incubated in the presence of 5 nM [3H]oxytocin or 5 nM [3H]vasopressin. In the forebrain, two types of neurohypophysial hormone binding site...

journal_title：Neuroscience

authors： Freund-Mercier MJ,Stoeckel ME,Dietl MM,Palacios JM,Richard P

更新日期：1988-07-01 00:00:00