Abstract:
:The effects of castration and hormone treatment on cognitive performance were evaluated in male rats. Castrated animals received either testosterone or estradiol and were compared with gonadally intact animals and with castrated controls. Results revealed a dissociation between the effects of testosterone and estradiol on cognitive performance in male rats. Specifically, estradiol enhanced acquisition of a delayed matching-to-position spatial task, similar to previously published observations in females. In contrast, neither castration nor testosterone treatment had any significant effect on acquisition of the delayed matching-to-position task, but did appear to affect delay-dependent working memory. None of the treatments had any significant effect on acquisition of a configural association negative patterning task, suggesting that effects on the delayed matching-to-position task were not due to effects on motivational factors. These data demonstrate that, as in females, gonadal hormones influence cognitive performance in males and suggest that estradiol and testosterone affect distinct cognitive domains.
journal_name
Horm Behavjournal_title
Hormones and behaviorauthors
Gibbs RBdoi
10.1016/j.yhbeh.2005.03.005keywords:
subject
Has Abstractpub_date
2005-09-01 00:00:00pages
268-77issue
3eissn
0018-506Xissn
1095-6867pii
S0018-506X(05)00084-Xjournal_volume
48pub_type
杂志文章abstract::Ghrelin is an orexigenic hormone that regulates homeostatic and reward-related feeding behavior. Recent evidence indicates that acylation of ghrelin by the gut enzyme ghrelin O-acyl transferase (GOAT) is necessary to render ghrelin maximally active within its target tissues. Here we tested the hypothesis that GOAT act...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2012.08.009
更新日期:2012-11-01 00:00:00
abstract::Fighting behavior between male copperheads (Agkistrodon contortrix) occurs during the two mating periods (late summer/fall and spring) to gain priority of access to females. Fights are characterized by prominent vertical challenge displays, swaying, and a high degree of physical contact that does not involve biting. A...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1996.0009
更新日期:1996-03-01 00:00:00
abstract::The hormonal control of territorial aggression in male and female vertebrates outside the breeding season is still unresolved. Most vertebrates have regressed gonads when not breeding and do not secrete high levels of sex steroids. However, recent studies implicate estrogens in the regulation of non-breeding territori...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2003.08.002
更新日期:2004-01-01 00:00:00
abstract::Estrogen impairs performance on some striatum-sensitive tasks of learning and memory. Evidence indicates that it may have these impairing effects by creating a bias to use hippocampally based strategies to solve tasks whether or not it is advantageous to do so. Estrogen may also exert direct effects in the striatum to...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2005.05.001
更新日期:2006-01-01 00:00:00
abstract::The present study investigates the effects of the antiestrogen ICI 182,780 (ICI) on the display of sexual behaviors in female rats. ICI 182,780 is a pure anti-estrogen and when given systemically, ICI is thought to act only in the periphery, and is not believed to cross the blood brain barrier. The present study exami...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.2000.1638
更新日期:2001-03-01 00:00:00
abstract::Food restricting lactating rat dams over the first 2 weeks of lactation results in a prolongation of the period of lactational diestrus. Such food restriction has not only a direct effect on the dam but also the pups are undernourished, and the pattern of dam-litter contact is also changed. In a series of studies, we ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1995.1012
更新日期:1995-06-01 00:00:00
abstract::Melatonin has been suggested to affect human emotion, but conflicting evidence exists. Therefore, we tested the effect of a single dose of a 4 mg prolonged release formulation of melatonin on a biologically based model of emotional processing. Affective modulation of acoustic white noise startle (103 dB) by emotional ...
journal_title:Hormones and behavior
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.yhbeh.2008.03.013
更新日期:2008-08-01 00:00:00
abstract::The aim of this study was to examine changes in rat emotional behavior and determine differences in the expression of GABA-A receptor alpha-2 subunits in brain structures of low- (LR) and high-anxiety (HR) rats after the repeated corticosterone administration. The animals were divided into LR and HR groups based on th...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2013.10.011
更新日期:2014-01-01 00:00:00
abstract::There is recent evidence that cryoanesthesia, commonly used during neonatal hormone manipulations (e.g., gonadectomy), has deleterious effects on the morphology of the splenium of the corpus callosum and primary visual cortex in adult rats of both sexes. (Nuñez and Juraska, 1998; Nuñez, Kim, and Juraska, 1998). In the...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.2000.1572
更新日期:2000-05-01 00:00:00
abstract::The present studies assessed the extent to which heterosexual pairmates could buffer marmosets (Wied's black tufted-ear marmoset, Callithrix kuhli) against stress. Six male and six female marmosets from established groups were exposed to two experimental manipulations together with a control condition. Each condition ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1998.1469
更新日期:1998-12-01 00:00:00
abstract::Fetal programming is emerging as a major conceptual model for understanding developmental origins of health and disease, including behavioral outcomes. As part of a larger study of prenatal stress and child development, we examined the association between prenatal hormone exposure and fear reactivity, a temperament di...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2009.12.012
更新日期:2010-03-01 00:00:00
abstract::Sexual behavior of men with secondary hypogonadism was studied. Seven of the thirteen subjects presented with hypogonadism secondary to isolated gonadotropin (Gn) deficit, whereas the other six had idiopathic prepubertal anterior panhypopituitarism. Testosterone (T) levels were low and did not differ between the two g...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(90)90003-g
更新日期:1990-06-01 00:00:00
abstract::In previous studies, we showed for the first time that prenatal stress in rats produces long-term alterations of formalin-induced pain behavior that are dependent on age and sex, and we demonstrated an important role of the serotonergic system in mechanisms of prenatal stress (Butkevich, I.P. and Vershinina, E.A., 200...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2008.09.008
更新日期:2009-01-01 00:00:00
abstract::Aggressive interactions in Anolis carolinensis result in increased circulating levels of epinephrine (Epi) and norepinephrine (NE) and conspicuous color changes. This activation of the adrenergic component of an acute stress response is externally represented by the darkening of the postorbital eyespot of A. carolinen...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1994.1003
更新日期:1994-03-01 00:00:00
abstract::Lesions of the preoptic area and immediately adjacent septal area were made in female American toads, Bufo americanus. The ability to show mating call phonotaxis (MCP) was then tested for. The intensity of MCP was found to decrease as the degree of damage to the anterior tip of the anterior preoptic nucleus (APON) inc...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(89)90070-6
更新日期:1989-03-01 00:00:00
abstract::Since Arnold Adolph Berthold established in 1849 the critical role of the testes in the activation of male sexual behavior, intensive research has identified many sophisticated neurochemical and molecular mechanisms mediating this action. Studies in Japanese quail demonstrated the critical role of testosterone action ...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1016/j.yhbeh.2017.05.017
更新日期:2017-07-01 00:00:00
abstract::C-peptide of insulin presents a promising new tool for behavioral ecologists that allows for regular, non-invasive assessment of energetic condition in wild animals. C-peptide is produced on an equimolar basis with insulin, thus is indicative of the body's response to available glucose and, with repeated measurement, ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2008.11.005
更新日期:2009-02-01 00:00:00
abstract::Social relationships among spouses, family members, and friends are known to affect physical and mental health. In particular, long-lasting bonds between socio-sexual partners have profound effects on cognitive, social, emotional, and physical well-being. We have previously reported that pair bonding in monogamous pra...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2020.104685
更新日期:2020-04-01 00:00:00
abstract::These experiments were designed to investigate the role of neuronal protein synthesis in the hormonal activation of female sexual behavior using intracranial implants of the protein synthesis inhibitor, anisomycin. In the first experiment, female rats receiving bilateral cannulae implants in the medial preoptic area (...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(85)90024-8
更新日期:1985-09-01 00:00:00
abstract::Oxytocin is important for postnatal developmental experiences for mothers, infants, and transactions between them. Oxytocin is also implicated in adult affiliative behaviors, including social buffering of stress. There is evidence for connections between early life experience and adult oxytocin system functioning, but...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2020.104822
更新日期:2020-11-01 00:00:00
abstract::The effect of a high-fat diet on growth, sexual maturation, and developmental changes in serum levels of estradiol (E2), growth hormone (GH), somatomedin-C (Sm-C), and insulin were examined in outdoor-housed premenarchial rhesus monkeys. From 16 to 32 months of age, females were fed either a high-fat diet (HFD, N = 5)...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(88)90069-4
更新日期:1988-06-01 00:00:00
abstract::A series of six experiments was performed to examine the influence of postnatal-gonadal-hormone exposure on home-cage activity in Rockland-Swiss albino mice. Intact females were more active than their male counterparts and gonadectomy in adulthood, while reducing levels of the behavior in both sexes, did not eliminate...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(84)90051-5
更新日期:1984-03-01 00:00:00
abstract::Adolescence is a period during which many social behaviors emerge. One such behavior, flank marking, is a testosterone-modulated scent marking behavior that communicates dominance status between adult male Syrian hamsters. Testosterone modulates flank-marking behavior by altering neural transmission of vasopressin wit...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2006.06.006
更新日期:2006-09-01 00:00:00
abstract::Female hormonal contraceptive use has been associated with a variety of physical and psychological side effects. Women who use hormonal contraceptives report more intense affective responses to partner infidelity and greater overall sexual jealousy than women not using hormonal contraceptives. Recently, researchers ha...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2011.10.011
更新日期:2012-01-01 00:00:00
abstract::The intravenous injection of several corticosteroids in the spayed estrogen-primed rat resulted, 5 min later, in a remarkable induction of lordosis response for deoxycorticosterone and 11-deoxycortisol. A lower but important effect was induced with corticosterone and 17 alpha-hydroxyprogesterone. A chemical structure-...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(90)90033-t
更新日期:1990-12-01 00:00:00
abstract::Species with alternative reproductive tacts are good models to investigate the poorly understood question of whether individual variation within sexes results from the same physiological mechanisms that control variation between sexes. We have shown previously that adult male tree lizards, Urosaurus ornatus, of differ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(92)90023-o
更新日期:1992-12-01 00:00:00
abstract::A sequence of behaviours which we call courtship initiates reproduction in a large number of species. In vertebrates, as a component of male sexual behaviour courtship is strongly influenced by testicular androgen. Here I will review some salient issues about the regulation of courtship by testosterone in birds. The f...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1016/j.yhbeh.2008.04.004
更新日期:2008-08-01 00:00:00
abstract::Semelparous Pacific salmon (Onchorynchus spp.) serve as an excellent model for examining the relationships between life history, behavior and individual variation in glucocorticoid (GC) stress hormone levels because reproductive behaviors are highly variable between individuals and failure to reproduce results in zero...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2011.07.017
更新日期:2011-11-01 00:00:00
abstract::Perinatal treatment of female rats with androgen decreases the nuclear volume of the anteroventral periventricular nucleus of the preoptic area (AVPvN-POA). In order to examine the effect of androgen on neurogenesis, bromodeoxyuridine (BrdU) was given once on Day 15 of gestation (= E15) to pregnant rats that also rece...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1994.1027
更新日期:1994-12-01 00:00:00
abstract::The anti-estrogen tamoxifen (Tam), which has been shown to dramatically suppress offensive behavior in male rats without markedly influencing other aspects of the social encounter, was tested for its effectiveness in mice. TO strain albino mice were given control injections or 50 or 100 micrograms of Tam for 4 or 8 da...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(88)90064-5
更新日期:1988-06-01 00:00:00