Abstract:
:These experiments were designed to investigate the role of neuronal protein synthesis in the hormonal activation of female sexual behavior using intracranial implants of the protein synthesis inhibitor, anisomycin. In the first experiment, female rats receiving bilateral cannulae implants in the medial preoptic area (POA), septal region (SEPT), ventromedial hypothalamus (VMH), or midbrain central gray (CG) were injected with 2.5 micrograms estradiol benzoate (EB), followed 48 hr later by 500 micrograms progesterone (P). Females receiving anisomycin in the VMH at the time of EB injection had lower levels of lordosis and darting compared to tests without anisomycin. Sexual behavior was unaffected in females receiving anisomycin implants in the POA, SEPT, or CG. In a second experiment, we replicated the finding that anisomycin could attenuate lordotic responsivity when placed in the VMH of female rats injected with 2.5 micrograms EB and 500 micrograms P. In addition, we found that POA implants of anisomycin could facilitate lordosis in females given a low dose of EB (1.25 microgram) plus 500 micrograms P. In a third experiment, we assessed the effects of anisomycin application to the VMH or POA of female rats receiving estradiol (E; diluted 1:250 with cholesterol) implants in the VMH and systemic P. Treatment of the VMH with anisomycin prior to E in the VMH suppressed lordotic responding, whereas anisomycin application to the POA prior to E in the VMH had no effect on lordosis. The results of these experiments suggest that reducing protein synthesis in the region of the VMH disrupts the action of estrogen on the VMH, and that the facilitative action of anisomycin in the POA of female rats requires more estrogen treatment than threshold stimulation of the VMH alone.
journal_name
Horm Behavjournal_title
Hormones and behaviorauthors
Meisel RL,Pfaff DWdoi
10.1016/0018-506x(85)90024-8subject
Has Abstractpub_date
1985-09-01 00:00:00pages
237-51issue
3eissn
0018-506Xissn
1095-6867pii
0018-506X(85)90024-8journal_volume
19pub_type
杂志文章abstract::Androgens are an important class of steroid hormones involved in modulating the expression and evolution of male secondary sex characters. Vocalizations used in the context of aggression and mate attraction are among the most elaborate and diverse androgen-dependent animal displays as reflected in a rich tradition of ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2010.10.011
更新日期:2011-01-01 00:00:00
abstract::This article is part of a Special Issue "Chemosignals and Reproduction". A rich variety of chemosignals have been identified that influence mammalian behaviour, including peptides, proteins and volatiles. Many of these elicit innate effects acting either as pheromones within species or allelochemicals between species....
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1016/j.yhbeh.2014.08.010
更新日期:2015-02-01 00:00:00
abstract::Glucocorticoids have wide-ranging effects on animals' behaviour, but many of these effects remain poorly understood because numerous confounding factors have often been neglected in previous studies. Here, we present data from a 2-year study of 7 groups of wild Verreaux's sifakas (Propithecus verreauxi), in which we e...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2020.104760
更新日期:2020-08-01 00:00:00
abstract::Primates develop slowly relative to their body size, a pattern posited to result from ecological risk aversion. Little is known, however, about how energy balance contributes to allostatic load in juveniles. Using data collected over 8 consecutive months, we examined variation in energy balance (as measured by urinary...
journal_title:Hormones and behavior
pub_type: 杂志文章,收录出版
doi:10.1016/j.yhbeh.2018.12.014
更新日期:2019-02-01 00:00:00
abstract::Women's ovulation is perceivable with different senses. Already subtle face shape differences are enough to trigger men's preference for the ovulatory female. The aim of the present study is to investigate if men's testosterone level can be linked to their preference for the ovulatory female. Thirty-nine heterosexual ...
journal_title:Hormones and behavior
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.yhbeh.2014.06.015
更新日期:2014-08-01 00:00:00
abstract::Reproductive success is maximized when female sexual motivation and behavior coincide with the time of optimal fertility. Both processes depend upon coordinated hormonal events, beginning with signaling by the gonadotropin-releasing hormone (GnRH) neuronal system. Two neuropeptidergic systems that lie upstream of GnRH...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2013.06.006
更新日期:2013-08-01 00:00:00
abstract::Animals living in temperate climates with predictable seasonal changes in food availability may use seasonal information to engage different metabolic strategies. Siberian hamsters decrease costs of thermoregulation during winter by reducing food intake and body mass in response to decreasing or short-day lengths (SD)...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2010.06.009
更新日期:2010-09-01 00:00:00
abstract::Among rodents that carry hantaviruses, males are more likely to engage in aggression and to be infected than females. One mode of hantavirus transmission is via the passage of virus in saliva during wounding. The extent to which hantaviruses cause physiological changes in their rodent host that increase aggression and...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2007.07.001
更新日期:2007-11-01 00:00:00
abstract::Conspicuous swellings of the perineal skin can be observed in females of many catharrine primate species particularly during the middle stages of the ovarian cycle. The functional significance of this trait remains poorly understood. Recently, two hypotheses, the "reliable indicator" hypothesis and the "graded signal"...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2004.03.013
更新日期:2004-08-01 00:00:00
abstract::The time of day at which mating occurs is dramatically different in diurnal compared to nocturnal rodents. We used a diurnal murid rodent, Arvicanthis niloticus, to determine if inverted rhythms in responsiveness to hormones contribute to this difference. Male and hormone-primed female grass rats were tested for matin...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2004.07.006
更新日期:2005-01-01 00:00:00
abstract::Among the suite of seasonal adaptations displayed by nontropical rodents, some species demonstrate increased territorial aggression in short compared with long day lengths despite basal levels of testosterone. The precise physiological mechanisms mediating seasonal changes in aggression, however, remain largely unknow...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2004.07.001
更新日期:2004-12-01 00:00:00
abstract::Previous studies have documented the ability of neural grafts to stimulate the recovery of lordosis from neurochemical deficits. However, it was unclear if grafts also could reverse deficits in lordosis caused by lesions at critical points in the neural circuit controlling this response. To address this question, fema...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1997.1421
更新日期:1997-12-01 00:00:00
abstract::The neuropeptide Oxytocin (OT) has been implicated in many aspects of mammalian social behavior. This study investigates how OT interacts with two well-studied determinants of cooperative behavior: incentives and social information. Participants received OT or a placebo and played two economic games: a Coordination Ga...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2010.01.006
更新日期:2010-03-01 00:00:00
abstract::Sex steroids were initially defined by their actions shaping sexually dimorphic behavioral patterns. More recently scientists have begun exploring the role of steroids in determining sex differences in behavioral plasticity. We investigated the role of androgens in potentiating circadian, pharmacological, and socially...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2009.05.005
更新日期:2009-08-01 00:00:00
abstract::In human females cyclic shifts in preference have been documented for odour and physical and behavioral male traits. Women prefer the smell of dominant males, more masculine male faces and men behaving more dominantly when at peak fertility than at other times in their menstrual cycle. Here we examine variation in pre...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2007.03.006
更新日期:2007-05-01 00:00:00
abstract::Among the suite of adaptations displayed by seasonally-breeding rodents, individuals of most species display reproductive regression and concomitant decreases in gonadal steroids during the winter. In addition, some species display increased aggression in short "winter-like" days compared with long "summer-like" day l...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2007.03.029
更新日期:2007-08-01 00:00:00
abstract::When ovariectomized/adrenalectomized female rats, injected with subthreshold doses of estradiol are given copulatory stimulation by a male rat at half hour intervals, the level of lordosis gradually increases over the course of a few hours. We tested the hypothesis that paracopulatory behaviors (behaviors that occur r...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2008.12.008
更新日期:2009-03-01 00:00:00
abstract::Half a century has passed since the first report of the influence of odors on mice. Odors are known to influence behavior (signaling effect) and affect the physiology (primer effect) of mice. This review focuses on summarizing the primer effects found so far in female and male mice. Odors from conspecifics of the oppo...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1016/j.yhbeh.2004.03.002
更新日期:2004-09-01 00:00:00
abstract::A meta-analysis of the literature shows that in adult male songbirds, brain mass, telencephalon volume and n. rotundus (a thalamic visual nucleus) volume increase from the nonbreeding season (low testosterone) to the breeding season (higher testosterone). These effects can at least partially be mimicked by photoperiod...
journal_title:Hormones and behavior
pub_type: 杂志文章,meta分析
doi:10.1006/hbeh.2001.1748
更新日期:2002-03-01 00:00:00
abstract::Testosterone is thought to be positively associated with "mating effort", or the initiation and establishment of sexual relationships (Wingfield et al., 1990). Yet, because testosterone is negatively associated with nurturance (van Anders et al., 2011), high levels of testosterone may be incompatible with relationship...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2014.03.003
更新日期:2014-04-01 00:00:00
abstract::In New World monkeys of the family Callitrichidae (marmosets and tamarins), females frequently give birth to dizygotic twins. Twins share a placental circulation throughout fetal development and are hemopoietic chimeras. Despite this, there is no masculinization (freemartinism) in females which develop next to a male ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1993.1016
更新日期:1993-06-01 00:00:00
abstract::The anti-estrogen tamoxifen (Tam), which has been shown to dramatically suppress offensive behavior in male rats without markedly influencing other aspects of the social encounter, was tested for its effectiveness in mice. TO strain albino mice were given control injections or 50 or 100 micrograms of Tam for 4 or 8 da...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(88)90064-5
更新日期:1988-06-01 00:00:00
abstract::Ghrelin, a hormone produced primarily by the stomach, has been associated with motivational processes that include reward-seeking behaviors. In male laboratory mice, elevation of ghrelin levels enhances some aspects of sexual motivation and behavior, whereas in other experiments with male mice, rats, and other species...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2017.10.012
更新日期:2018-01-01 00:00:00
abstract::Sexual behavior in female rats depends on the action of estradiol on estrogen receptors (ERs) found in particular brain regions. While hormonal regulation of female sexual behavior requires ERalpha, the possible functions of ERbeta remain to be clarified. Mating stimulation has several behavioral and physiological con...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/s0018-506x(03)00028-x
更新日期:2003-04-01 00:00:00
abstract::Previous experiments demonstrate that lesions of the septum produce opposite effects on intraspecific male aggression in the territorial field sparrow (Spizella pusilla) and the colonial zebra finch (Taeniopygia guttata; facilitate vs inhibit, respectively) and intraseptal infusions of arginine vasotocin (AVT) and vas...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1998.1467
更新日期:1998-08-01 00:00:00
abstract::From an evolutionary point of view, female sexual desire contributes greatly to the success of reproduction by coordinating sexual behavior. It is known that female sexual desire fluctuates with the menstrual cycle. However, little is known about the role of basic emotions during menstrual cycle. We designed a facial ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2008.06.007
更新日期:2009-02-01 00:00:00
abstract::Introducing an aggressive intruder into a cage of mice (social disruption, SDR) resulted in intense fighting and defeat of the cage residents. Defeat was accompanied by elevated levels of serum corticosterone and nerve growth factor (NGF). Repeated exposure to an intruder induced a state of glucocorticoid resistance i...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.2001.1653
更新日期:2001-06-01 00:00:00
abstract::cDNAs encoding for neuropeptide Y (NPY), cocaine and amphetamine regulated transcript (CART) and cholecystokinin (CCK) were cloned in winter flounder, a species that undergoes a period of natural fasting during the winter. Tissue distribution studies show that these peptides are present in several peripheral tissues, ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2009.03.002
更新日期:2009-06-01 00:00:00
abstract::Blood samples were taken from free-living male and female mockingbirds to determine correlations between plasma steroids and breeding behavior. Plasma levels of testosterone (T), estradiol (E2), progesterone (P), and corticosterone (B) were assessed during pre-breeding courtship, while males built nests, while females...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1995.1002
更新日期:1995-03-01 00:00:00
abstract::Daily sexual activity of sexually active lesbian couples was recorded over a 14-week period. Significant peaks in sexual encounters and orgasms were found during the midcycle portion of the menstrual cycle. These results demonstrate a pattern of increased midcycle sexual activity independent of interactions with males...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(84)90014-x
更新日期:1984-09-01 00:00:00