Abstract:
:Previous studies have documented the ability of neural grafts to stimulate the recovery of lordosis from neurochemical deficits. However, it was unclear if grafts also could reverse deficits in lordosis caused by lesions at critical points in the neural circuit controlling this response. To address this question, female hamsters were subjected to unilateral lesions of the ventromedial hypothalamus (VMN), a structure well known for its mediation of hormonal effects on lordosis. The effects of these lesions were described by noting the ability of manual stimulation of one flank to reinstate a deteriorating lordosis response. Consistent with past results, unilateral VMN lesions decreased responsiveness to stimulation of just the contralateral flank. Females showing such lateralized decrements then received control treatments or implants into the lesioned area of basal hypothalamic tissue from a neonatal male or female hamster. Approximately 1 month later, tests of lordosis reinstatement by ipsi- or contralateral manual stimuli were repeated. Whereas lateralized decrements in responsiveness persisted in control subjects, implants of tissue from male or female neonates led to reliable improvements in lordosis, reversing the lesion-induced decrease in contralateral responsiveness. The mechanism responsible for this change is unclear, but could involve an elevation in a lordosis-facilitating neuromodulator. Alternatively, it could depend on the reinforcement or replacement of neural circuits for lordosis, possibly including those that connect the two VMNs with each other or with the periaqueductal gray of the midbrain.
journal_name
Horm Behavjournal_title
Hormones and behaviorauthors
Bartholomew MB,Floody ORdoi
10.1006/hbeh.1997.1421subject
Has Abstractpub_date
1997-12-01 00:00:00pages
192-200issue
3eissn
0018-506Xissn
1095-6867pii
S0018-506X(97)91421-5journal_volume
32pub_type
杂志文章abstract::The role of reproductive hormones in mediating sexual desire in healthy women is still unclear. Elucidation was sought in this study by comparing the hormonal milieu of two groups of subjects with markedly different levels of sexual desire. Seventeen women ages 27-39 who met DSM III-R criteria for severe, persistent, ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(89)90063-9
更新日期:1989-06-01 00:00:00
abstract::Testosterone plays a key role in the expression of male sex behavior by influencing cellular activity and synapses within the magnocellular medial preoptic nucleus (MPN mag), a sub-nucleus of the medial preoptic area (MPOA) in the Syrian hamster. Although the mechanisms underlying hormonally-induced synaptic plasticit...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2018.05.006
更新日期:2018-06-01 00:00:00
abstract::In vertebrates, the well established increase in plasma corticosterone in response to food shortage is thought to mediate adjustments of foraging behavior and energy allocation to environmental conditions. However, investigating the functional role of corticosterone is often constrained by the difficulty to track time...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2007.07.003
更新日期:2007-11-01 00:00:00
abstract::Relationships between testosterone plasma levels and evoked vocal responses of males of the leptodactylid frog Batrachyla taeniata from southern Chile were studied. Evoked vocal responses were elicited in the field with playbacks of a synthetic imitation of the conspecific advertisement call and variants of this signa...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1997.1366
更新日期:1997-04-01 00:00:00
abstract::Recognition memory and anxiety were examined in nulliparous (NP: 0 litters) and multiparous (MP: 5-6 litters) middle-aged female rats (12 months old) to assess possible enduring effects of multiparity at least 3 months after the last litter was weaned. MP females performed significantly better than NP females on the n...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2007.08.011
更新日期:2008-06-01 00:00:00
abstract::Social behavior plays a significant role in the formation of social structure and population regulation in both animals and humans. Oxytocin (OXT) and its receptor (OXTR) are well known for regulating social behaviors, but their upstream regulating factors are rarely investigated. We hypothesized that the phosphorylat...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2019.104638
更新日期:2020-03-01 00:00:00
abstract::Fetal programming is emerging as a major conceptual model for understanding developmental origins of health and disease, including behavioral outcomes. As part of a larger study of prenatal stress and child development, we examined the association between prenatal hormone exposure and fear reactivity, a temperament di...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2009.12.012
更新日期:2010-03-01 00:00:00
abstract::The aim of this study was to examine changes in rat emotional behavior and determine differences in the expression of GABA-A receptor alpha-2 subunits in brain structures of low- (LR) and high-anxiety (HR) rats after the repeated corticosterone administration. The animals were divided into LR and HR groups based on th...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2013.10.011
更新日期:2014-01-01 00:00:00
abstract::In vertebrates, glucocorticoid secretion occurs in response to energetic and psychosocial stressors that trigger the hypothalamic-pituitary-adrenal (HPA) axis. Measuring glucocorticoid concentrations can therefore shed light on the stressors associated with different social and environmental variables, including domin...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2020.104826
更新日期:2020-09-01 00:00:00
abstract::The objectives of these studies were to evaluate the influence of testosterone propionate (TP), estradiol cypionate (EC), dihydrotestosterone propionate (DHTP), EC + TP, EC + DHTP, and TP + DHTP on traits of masculine sexual behavior in castrated adult male pigs of different breeds. Masculine sexual behavior was resto...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(89)90052-4
更新日期:1989-09-01 00:00:00
abstract::Seasonal changes in the length of the daily photoperiod induce significant changes in social behavior. Hamsters housed in winter-like short photoperiods (SP) can express significantly higher levels of aggression than hamsters housed in long photoperiods (LP) that mimic summer. The mechanisms responsible for increasing...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2009.08.007
更新日期:2009-10-01 00:00:00
abstract::Ovarian steroid hormones, estradiol and progesterone, regulate cellular functions in the central nervous system, resulting in the alterations in physiology and reproductive behavior. One means by which steroid hormones exert their neural effects on reproductive behavior is via their intracellular receptors functioning...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1006/hbeh.2001.1687
更新日期:2001-09-01 00:00:00
abstract::Exposure of female rats to estradiol during the perinatal period has profound effects on GABAergic neurotransmission that are crucial to establish sexually dimorphic brain characteristics. We previously showed that neonatal β-estradiol 3-benzoate (EB) treatment decreases brain concentrations of the neurosteroid allopr...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2016.10.005
更新日期:2017-01-01 00:00:00
abstract::One brain region that has been implicated in the regulation of lordosis is the medial preoptic-anterior hypothalamic continuum (MPOA-AH). Previous studies have suggested that this zone may be part of the circuit mediating the effects of serotonin (5-HT) on sexual receptivity. In the present experiments, we investigate...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.2002.1803
更新日期:2002-08-01 00:00:00
abstract::Developmental plasticity of HPA and fear responses in rats has been proposed to be mediated by environment-dependent variation in active maternal care. Here, we review this maternal mediation hypothesis based on the postnatal manipulation literature and on our own recent research in rats. We show that developmental pl...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1016/j.yhbeh.2006.06.015
更新日期:2006-12-01 00:00:00
abstract::This paper reviews evidence that, in some cases, steroid hormones rapidly modulate behaviors by binding to specific cell-surface receptors on neurons. The evidence comes from research with an amphibian model, Taricha granulosa. In Taricha, stress and corticosterone inhibit reproductive behaviors with a rapidity that i...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1006/hbeh.1994.1049
更新日期:1994-12-01 00:00:00
abstract::The influence of neonatal androgen on the potential to exhibit feminine sexual behavior was investigated. Male rats castrated on Day 0 but not those castrated on Day 4 or later showed hop/darting, ear wiggling, and lordotic behavior in response to treatment with estrogen and progesterone in adulthood at a frequency eq...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(88)90008-6
更新日期:1988-09-01 00:00:00
abstract::Oxytocin is important for postnatal developmental experiences for mothers, infants, and transactions between them. Oxytocin is also implicated in adult affiliative behaviors, including social buffering of stress. There is evidence for connections between early life experience and adult oxytocin system functioning, but...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2020.104822
更新日期:2020-11-01 00:00:00
abstract::Many species, including humans, engage in a series of behaviors that are preparatory to the arrival of offspring. Such "nesting behaviors" are of obvious importance, but relevant neuroendocrine mechanisms remain little studied. We here focus on the potential roles of vasoactive intestinal polypeptide (VIP) in the perf...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2014.12.010
更新日期:2015-03-01 00:00:00
abstract::Avian eggs contain substantial amounts of maternal yolk androgens, which have been shown to modulate offspring phenotype. The first studies on the functional consequences of maternal yolk androgens have focused on early life stages and their role in sibling competition. However, recent longitudinal studies reported lo...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2008.02.005
更新日期:2008-06-01 00:00:00
abstract::In many species, females are more sexually attractive to males near ovulation. Some evidence suggests a similar pattern in humans, but methodological limitations prohibit firm conclusions at present, and information on physiological mechanisms underlying any such pattern is lacking. In 202 normally-cycling women, we e...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2012.11.007
更新日期:2013-01-01 00:00:00
abstract::Androgens act on the CNS to affect motor function through interaction with a widespread distribution of intracellular androgen receptors (AR). This review highlights our work on androgens and process outgrowth in motoneurons, both in vitro and in vivo. The actions of androgens on motoneurons involve the generation of ...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1016/j.yhbeh.2008.01.014
更新日期:2008-05-01 00:00:00
abstract::In a previous study we found that mother rats show more drinking responses than virgins in the punished drinking paradigm, an animal model for anxiety. The present investigation was carried out to determine the possible mechanisms underlying this naturally occurring anticonflict effect. In Experiment 1, we investigate...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/0018-506x(90)90004-h
更新日期:1990-06-01 00:00:00
abstract::Appropriate timing of migratory behavior is critical for migrant species. For many temperate zone birds in the spring, lengthening photoperiod is the initial cue leading to morphological, physiological and behavior changes that are necessary for vernal migration and breeding. Strong evidence has emerged in recent year...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2016.05.021
更新日期:2016-08-01 00:00:00
abstract::This article is part of a Special Issue "Energy Balance". The classical estrogen receptors, estrogen receptor-α and estrogen receptor-β are well established in the regulation of body weight and energy homeostasis in both male and female mice, whereas, the role for G protein-coupled estrogen receptor 1 (GPER) as a modu...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2014.02.004
更新日期:2014-06-01 00:00:00
abstract::In rodents, parts of the arginine-vasopressin (AVP) neuronal system are sexually dimorphic with males having more AVP-immunoreactive cells/fibers than females. This neuropeptide neuronal system is highly sensitive to steroids and has been proposed to play an important role in the processing of olfactory cues critical ...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2008.02.001
更新日期:2008-06-01 00:00:00
abstract::Glucocorticoids have wide-ranging effects on animals' behaviour, but many of these effects remain poorly understood because numerous confounding factors have often been neglected in previous studies. Here, we present data from a 2-year study of 7 groups of wild Verreaux's sifakas (Propithecus verreauxi), in which we e...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2020.104760
更新日期:2020-08-01 00:00:00
abstract::This article is part of a Special Issue "Puberty and Adolescence". This paper examines consistency of effects of pubertal timing (going through puberty earlier, later or at the same time one's cohort of peers) on the development of psychopathology during adolescence as well as the persistence of effects into adulthood...
journal_title:Hormones and behavior
pub_type: 杂志文章,评审
doi:10.1016/j.yhbeh.2013.04.003
更新日期:2013-07-01 00:00:00
abstract::Women are at higher risk of anxiety and mood disorders, especially at transitions across the reproductive life cycle (premenstruum, postpartum, menopause). Premenstrual dysphoric disorder (PMDD) is one of female mood disorders associated with changing ovarian hormone levels. Because anxiety and depression frequently o...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1016/j.yhbeh.2006.09.006
更新日期:2007-01-01 00:00:00
abstract::The effects on adult sexually dimorphic behavior of perinatal exposure to estrogen were examined by treating male and female gray opossums with estradiol (EST), an estrogen receptor antagonist (tamoxifen:TX) or oil control (OIL) during the first week of life, a time period corresponding in this marsupial to late gesta...
journal_title:Hormones and behavior
pub_type: 杂志文章
doi:10.1006/hbeh.1999.1561
更新日期:2000-02-01 00:00:00