Ligand-independent activation of progestin receptors in sexual receptivity.

Abstract:

:Ovarian steroid hormones, estradiol and progesterone, regulate cellular functions in the central nervous system, resulting in the alterations in physiology and reproductive behavior. One means by which steroid hormones exert their neural effects on reproductive behavior is via their intracellular receptors functioning as ligand-dependent transcription factors. Studies from our laboratory in the past few years have shown that in addition to their cognate ligands, neurotransmitters like dopamine can activate intracellular steroid receptors in a ligand-independent manner. Using biochemical and molecular approaches we have demonstrated that the effects of neurotransmitter dopamine, on reproductive behavior in female rats and mice, occur by means of cross talk between membrane receptors for dopamine and intracellular progestin receptors (PRs). In this article, our studies on the integration of intracellular signaling pathways leading to the activation of PRs and its impact on modulation of reproductive behavior are summarized.

journal_name

Horm Behav

journal_title

Hormones and behavior

authors

Mani S

doi

10.1006/hbeh.2001.1687

keywords:

subject

Has Abstract

pub_date

2001-09-01 00:00:00

pages

183-90

issue

2

eissn

0018-506X

issn

1095-6867

pii

S0018-506X(01)91687-3

journal_volume

40

pub_type

杂志文章,评审
  • Compatibility drives female preference and reproductive success in the monogamous California mouse (Peromyscus californicus) more strongly than male testosterone measures.

    abstract::Female assessment of male attractiveness and how preferred qualities impact reproductive success is central to the study of mate choice. Male attractiveness may depend on traits beneficial to the reproductive success (RS) of any female, termed 'universal quality', and/or on behavioral and biological interactions betwe...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2011.10.009

    authors: Gleason ED,Holschbach MA,Marler CA

    更新日期:2012-01-01 00:00:00

  • Short-day increases in aggression are independent of circulating gonadal steroids in female Siberian hamsters (Phodopus sungorus).

    abstract::Among the suite of adaptations displayed by seasonally-breeding rodents, individuals of most species display reproductive regression and concomitant decreases in gonadal steroids during the winter. In addition, some species display increased aggression in short "winter-like" days compared with long "summer-like" day l...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2007.03.029

    authors: Scotti MA,Place NJ,Demas GE

    更新日期:2007-08-01 00:00:00

  • Ecoimmunology and microbial ecology: Contributions to avian behavior, physiology, and life history.

    abstract::Bacteria have had a fundamental impact on vertebrate evolution not only by affecting the evolution of the immune system, but also generating complex interactions with behavior and physiology. Advances in molecular techniques have started to reveal the intricate ways in which bacteria and vertebrates have coevolved. He...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.yhbeh.2016.12.003

    authors: Evans JK,Buchanan KL,Griffith SC,Klasing KC,Addison B

    更新日期:2017-02-01 00:00:00

  • Increased sexual activity during the midcycle portion of the human menstrual cycle.

    abstract::Daily sexual activity of sexually active lesbian couples was recorded over a 14-week period. Significant peaks in sexual encounters and orgasms were found during the midcycle portion of the menstrual cycle. These results demonstrate a pattern of increased midcycle sexual activity independent of interactions with males...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/0018-506x(84)90014-x

    authors: Matteo S,Rissman EF

    更新日期:1984-09-01 00:00:00

  • Ovarian hormones mediate running-induced changes in high fat diet choice patterns in female rats.

    abstract::Physical inactivity and increased consumption of energy dense, high fat (HF) foods often leads to a state of positive energy balance. Regular exercise can facilitate the maintenance of a healthy body weight and mediate changes in dietary selection. Past studies using a two-diet choice (chow vs. HF) and voluntary wheel...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2018.02.010

    authors: Yang TY,Liang NC

    更新日期:2018-04-01 00:00:00

  • Testosterone, antiandrogen, and alloparental behavior in bobwhite quail foster fathers.

    abstract::Vasectomized male Texas bobwhite quail (Colinus virginianus texanus) are used as foster fathers in a program to reintroduce the endangered masked bobwhite quail to its native habitat. Less than half of the Texas bobwhite, however, show appropriate alloparental behavior toward the chicks. They also undergo a significan...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1006/hbeh.1993.1007

    authors: Vleck CM,Dobrott SJ

    更新日期:1993-03-01 00:00:00

  • Dynamics and determinants of glucocorticoid metabolite concentrations in wild Verreaux's sifakas.

    abstract::Glucocorticoids have wide-ranging effects on animals' behaviour, but many of these effects remain poorly understood because numerous confounding factors have often been neglected in previous studies. Here, we present data from a 2-year study of 7 groups of wild Verreaux's sifakas (Propithecus verreauxi), in which we e...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2020.104760

    authors: Rudolph K,Fichtel C,Heistermann M,Kappeler PM

    更新日期:2020-08-01 00:00:00

  • Hormonal regulation of chemosignals of female mice that elicit ultrasonic vocalizations from males.

    abstract::Two experiments examined the properties of vaginal, facial, salivary, and urinary odors from female house mice to elicit ultrasonic vocalizations from male mice. Experiment 1 demonstrated that facial and salivary secretions from hypophysectomized females were significantly less effective in eliciting ultrasonic vocali...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/0018-506x(86)90029-2

    authors: Byatt S,Nyby J

    更新日期:1986-03-01 00:00:00

  • Testosterone reactivity to competition and competitive endurance in men and women.

    abstract::Transient shifts in testosterone occur during competition and are thought to positively influence dominance behavior aimed at enhancing social status. However, individual differences in testosterone reactivity to status contests have not been well-studied in relation to real-time expressions of competitive behavior am...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2019.104665

    authors: Casto KV,Edwards DA,Akinola M,Davis C,Mehta PH

    更新日期:2020-07-01 00:00:00

  • Dihydrotestosterone treatment delays the conversion from mild cognitive impairment to Alzheimer's disease in SAMP8 mice.

    abstract::The senescence-accelerated-prone mouse 8 (SAMP8) has been proposed as a suitable, naturally derived animal model for Alzheimer's disease (AD). In the current study, we focus on the problem whether SAMP8 mice show abnormal behavioral and neuropathological signs before they present the characteristic of AD. Our results ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2014.03.017

    authors: Kang L,Li S,Xing Z,Li J,Su Y,Fan P,Wang L,Cui H

    更新日期:2014-05-01 00:00:00

  • Photoperiodic regulation of the orexigenic effects of ghrelin in Siberian hamsters.

    abstract::Animals living in temperate climates with predictable seasonal changes in food availability may use seasonal information to engage different metabolic strategies. Siberian hamsters decrease costs of thermoregulation during winter by reducing food intake and body mass in response to decreasing or short-day lengths (SD)...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2010.06.009

    authors: Bradley SP,Pattullo LM,Patel PN,Prendergast BJ

    更新日期:2010-09-01 00:00:00

  • CRF type 1 receptors of the medial amygdala modulate inhibitory avoidance responses in the elevated T-maze.

    abstract::Corticotropin-releasing factor (CRF) plays a critical role in the mediation of physiological and behavioral responses to stressors. In the present study, we investigated the role played by the CRF system within the medial amygdala (MeA) in the modulation of anxiety and fear-related responses. Male Wistar rats were bil...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2014.01.004

    authors: Vicentini JE,Céspedes IC,Nascimento JO,Bittencourt JC,Viana MB

    更新日期:2014-03-01 00:00:00

  • Oxytocin receptor antagonist reverses the blunting effect of pair bonding on fear learning in monogamous prairie voles.

    abstract::Social relationships among spouses, family members, and friends are known to affect physical and mental health. In particular, long-lasting bonds between socio-sexual partners have profound effects on cognitive, social, emotional, and physical well-being. We have previously reported that pair bonding in monogamous pra...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2020.104685

    authors: Hirota Y,Arai A,Young LJ,Osako Y,Yuri K,Mitsui S

    更新日期:2020-04-01 00:00:00

  • Testosterone, endurance, and Darwinian fitness: natural and sexual selection on the physiological bases of alternative male behaviors in side-blotched lizards.

    abstract::The mechanistic bases of natural and sexual selection on physiological and behavioral traits were examined in male morphs of three colors of the side-blotched lizard, Uta stansburiana. Orange-throated males are aggressive and defend large territories with many females. Blue-throated males defend smaller territories wi...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1006/hbeh.2000.1622

    authors: Sinervo B,Miles DB,Frankino WA,Klukowski M,DeNardo DF

    更新日期:2000-12-01 00:00:00

  • Guest editor's introduction: Energy homeostasis in context.

    abstract::This article is part of a Special Issue "Energy Balance". Energy homeostasis is achieved through neuroendocrine and metabolic control of energy intake, storage, and expenditure. Traditionally, these controls have been studied in an unrealistic and narrow context. The appetite for food, for example, is most often assum...

    journal_title:Hormones and behavior

    pub_type: 社论

    doi:10.1016/j.yhbeh.2014.05.001

    authors: Schneider JE

    更新日期:2014-06-01 00:00:00

  • Developmental exposure to environmental estrogens alters anxiety and spatial memory in female mice.

    abstract::Humans and wildlife are exposed to numerous anthropogenic drugs and pollutants. Many of these compounds are hormonally active, and recent evidence suggests that the presence of these endocrine disruptors permanently alters normal development and physiology in a variety of vertebrate species. Here, we report on the eff...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2006.01.007

    authors: Ryan BC,Vandenbergh JG

    更新日期:2006-06-01 00:00:00

  • Why we haven't died out yet: changes in women's mimic reactions to visual erotic stimuli during their menstrual cycles.

    abstract::From an evolutionary point of view, female sexual desire contributes greatly to the success of reproduction by coordinating sexual behavior. It is known that female sexual desire fluctuates with the menstrual cycle. However, little is known about the role of basic emotions during menstrual cycle. We designed a facial ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2008.06.007

    authors: Mass R,Hölldorfer M,Moll B,Bauer R,Wolf K

    更新日期:2009-02-01 00:00:00

  • Digit ratio (2D:4D) and physical fitness in males and females: Evidence for effects of prenatal androgens on sexually selected traits.

    abstract::It has been suggested that male achievement in sports and athletics is correlated with a putative measure of prenatal testosterone the 2nd to 4th digit ratio (2D:4D). It is not known whether this association also extends to females, or whether the association results from an effect of testosterone on behavior (such as...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2005.11.006

    authors: Hönekopp J,T Manning J,Müller C

    更新日期:2006-04-01 00:00:00

  • Sex differences and developmental effects of oxytocin on aggression and social behavior in prairie voles (Microtus ochrogaster).

    abstract::Various hormones, including sex steroids and neuropeptides, have been implicated in aggression. In this study we examined (1) sex differences in intrasexual aggression in naïve prairie voles; (2) the effects of developmental manipulations of oxytocin on intrasexual aggression; and (3) changes in patterns of intrasexua...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/s0018-506x(03)00154-5

    authors: Bales KL,Carter CS

    更新日期:2003-09-01 00:00:00

  • Thinking about networks in the control of male hamster sexual behavior.

    abstract::Motivated social behaviors such as mating are controlled by a complex network of limbic nuclei. Concepts of network organization derived from computational neuroscience may aid our understanding of the links between the neuroanatomical circuitry and what is represented by the anatomy. Research in my laboratory uses ma...

    journal_title:Hormones and behavior

    pub_type: 杂志文章,评审

    doi:10.1006/hbeh.1997.1403

    authors: Wood RI

    更新日期:1997-08-01 00:00:00

  • Involvement of orexin in the regulation of stress, depression and reward in alcohol dependence.

    abstract::There is growing evidence from preclinical studies for an involvement of orexins (ORX) in the regulation of stress, affectivity and addictive behavior. The aim of our study was to gather corresponding clinical data and to elucidate the relationships between alcohol withdrawal stress, ORX plasma concentration and psych...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2011.08.017

    authors: von der Goltz C,Koopmann A,Dinter C,Richter A,Grosshans M,Fink T,Wiedemann K,Kiefer F

    更新日期:2011-11-01 00:00:00

  • Effects of estradiol in adult neurogenesis and brain repair in zebrafish.

    abstract::The brain of the adult teleost fish exhibits intense neurogenic activity and an outstanding capability for brain repair. Remarkably, the brain estrogen-synthesizing enzyme, aromatase B, is strongly expressed, particularly in adult fishes, in radial glial cells, which act as progenitors. Using zebrafish, we tested the ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2012.04.003

    authors: Diotel N,Vaillant C,Gabbero C,Mironov S,Fostier A,Gueguen MM,Anglade I,Kah O,Pellegrini E

    更新日期:2013-02-01 00:00:00

  • Antiphonal duetting and sex hormones in the tropical bush shrike Laniarius funebris (HARTLAUB).

    abstract::We investigated changes in antiphonal duetting with phases of reproduction and circulating levels of luteinizing hormone, testosterone, and estradiol in slate-colored boubous (Laniarius funebris) breeding in aviaries. Frequency of overall male singing did not vary with reproductive phase while frequencies of female si...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/0018-506x(92)90001-c

    authors: Schwabl H,Sonnenschein E

    更新日期:1992-09-01 00:00:00

  • Does access to the bluestreak cleaner wrasse Labroides dimidiatus affect indicators of stress and health in resident reef fishes in the Red Sea?

    abstract::Interactions between the bluestreak cleaner wrasse Labroides dimidiatus and its client reef fish are a textbook example of interspecific mutualism. The fact that clients actively visit cleaners and invite inspection, together with evidence that cleaners eat many client ectoparasites per day, indeed strongly suggests a...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2010.11.006

    authors: Ros AF,Lusa J,Meyer M,Soares M,Oliveira RF,Brossard M,Bshary R

    更新日期:2011-01-01 00:00:00

  • The absence of maternal pineal melatonin rhythm during pregnancy and lactation impairs offspring physical growth, neurodevelopment, and behavior.

    abstract::Maternal melatonin provides photoperiodic information to the fetus and thus influences the regulation and timing of the offspring's internal rhythms and preparation for extra-uterine development. There is clinical evidence that melatonin deprivation of both mother and fetus during pregnancy, and of the neonate during ...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2018.08.006

    authors: Motta-Teixeira LC,Machado-Nils AV,Battagello DS,Diniz GB,Andrade-Silva J,Silva S Jr,Matos RA,do Amaral FG,Xavier GF,Bittencourt JC,Reiter RJ,Lucassen PJ,Korosi A,Cipolla-Neto J

    更新日期:2018-09-01 00:00:00

  • Effects of long-term treatment with 17 beta-estradiol and medroxyprogesterone acetate on water maze performance in middle aged female rats.

    abstract::Although previous research has indicated that hormone replacement therapy benefits memory in menopausal women, several recent studies have shown either detrimental or no effects of treatment. These inconsistencies emphasize the need to evaluate the role of ovarian hormones in protecting against age-related cognitive d...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2010.03.018

    authors: Lowry NC,Pardon LP,Yates MA,Juraska JM

    更新日期:2010-07-01 00:00:00

  • Hormones, sexual signals, and performance of green anole lizards (Anolis carolinensis).

    abstract::The evolutionary processes that result in reliable links between male signals and fighting capacity have received a great deal of attention, but the proximate mechanisms underlying such connections remain understudied. We studied a large sample of male green anole lizards (Anolis carolinensis) to determine whether tes...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2007.05.014

    authors: Husak JF,Irschick DJ,Meyers JJ,Lailvaux SP,Moore IT

    更新日期:2007-09-01 00:00:00

  • Regulation of vernal migration in Gambel's white-crowned sparrows: Role of thyroxine and triiodothyronine.

    abstract::Appropriate timing of migratory behavior is critical for migrant species. For many temperate zone birds in the spring, lengthening photoperiod is the initial cue leading to morphological, physiological and behavior changes that are necessary for vernal migration and breeding. Strong evidence has emerged in recent year...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2016.05.021

    authors: Pérez JH,Furlow JD,Wingfield JC,Ramenofsky M

    更新日期:2016-08-01 00:00:00

  • Individualities in a flock of free-roaming greylag geese: behavioral and physiological consistency over time and across situations.

    abstract::The concept of personality implies individual differences in behavior and physiology that show some degree of repeatability/consistency over time and across contexts. Most studies of animal personality, particularly studies of individuals' variation in physiological mechanisms, have been conducted on selected individu...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2006.10.006

    authors: Kralj-Fiser S,Scheiber IB,Blejec A,Moestl E,Kotrschal K

    更新日期:2007-02-01 00:00:00

  • The face of female dominance: Women with dominant faces have lower cortisol.

    abstract::The human face displays a wealth of information, including information about dominance and fecundity. Dominance and fecundity are also associated with lower concentrations of the stress hormone cortisol, suggesting that cortisol may negatively predict facial dominance and attractiveness. We digitally photographed 61 w...

    journal_title:Hormones and behavior

    pub_type: 杂志文章

    doi:10.1016/j.yhbeh.2015.03.006

    authors: Gonzalez-Santoyo I,Wheatley JR,Welling LL,Cárdenas RA,Jimenez-Trejo F,Dawood K,Puts DA

    更新日期:2015-05-01 00:00:00