Preadipocytes in the human subcutaneous adipose tissue display distinct features from the adult mesenchymal and hematopoietic stem cells.

abstract：:Dietary fiber has been suggested to suppress colorectal cancer development, although the mechanisms contributing to this beneficial effect remain elusive. Butyrate, a fermentation product of fiber, has been shown to have anti-proliferative and pro-apoptotic effects on colorectal cancer cells. The metabolic fate of but...

journal_title：Journal of cellular physiology

authors： Han A,Bennett N,MacDonald A,Johnstone M,Whelan J,Donohoe DR

更新日期：2016-08-01 00:00:00

abstract：:Breast cancer (BC) is the most prevalent malignant cancer in the world, is the leading cause of cancer-related death female. Recently, there is accumulating evidence that long noncoding RNAs (lncRNAs) might as an important role in the progression of BC. (epithelial-mesenchymal transition (EMT) is considered to play a ...

journal_title：Journal of cellular physiology

authors： Wang YY,Yan L,Yang S,Xu HN,Chen TT,Dong ZY,Chen SL,Wang WR,Yang QL,Chen CJ

更新日期：2019-12-01 00:00:00

abstract：:Identification of cellular proteins, in addition to already known transcription factors such as NF-κB, Sp1, C-EBPβ, NFAT, ATF/CREB, and LEF-1, which interact with the HIV-1 LTR, is critical in understanding the mechanism of HIV-1 replication in monocytes/macrophages. Our studies demonstrate upregulation of pyruvate ki...

journal_title：Journal of cellular physiology

authors： Sen S,Deshmane SL,Kaminski R,Amini S,Datta PK

更新日期：2017-03-01 00:00:00

abstract：:Addition of prostaglandin E1 (PGE1) to quiescent cultures of Swiss 3T3 cells rapidly elevates the intracellular levels of cAMP and increases the activity of adenylate cyclase in particulate fractions of these cells. In the presence of insulin, PGE1 stimulates the reinitiation of DNA synthesis. Both effects (increase i...

journal_title：Journal of cellular physiology

authors： Rozengurt E,Collins MK,Keehan M

更新日期：1983-09-01 00:00:00

abstract：:Colon cancer remains one of the lethal malignancies in the world. Aberrant activation of canonical Wnt/β-catenin signaling pathway has been observed in colon cancer. In contrast, the non-canonical Wnt signaling functions remain obscure. Wnt5a is a representative non-canonical Wnt ligand which has gained extensive atte...

journal_title：Journal of cellular physiology

authors： Cheng R,Sun B,Liu Z,Zhao X,Qi L,Li Y,Gu Q

更新日期：2014-12-01 00:00:00

abstract：:Bethanechol, a muscarinic agonist, inhibits the initial rate of amiloride-sensitive Na uptake by intact mucosa of avian small intestine as well as by isolated chicken villus enterocytes, an effect that is maximal at 90 seconds and reverses by 6 minutes. Bethanechol similarly decreases intracellular pH in isolated cell...

journal_title：Journal of cellular physiology

authors： Musch MW,Drabik-Arvans D,Rao MC,Chang EB

更新日期：1992-08-01 00:00:00

abstract：:Aberrant expressions of microRNAs have been reported to be strongly associated with the progression and prognosis of various tumors, including oral squamous cell carcinoma (OSCC). Recent studies on miRNA expression profiling have suggested that microRNA-16 (miR-16) may be dysregulated in OSCC. However, the tumorigenic...

journal_title：Journal of cellular physiology

authors： Wang X,Li GH

更新日期：2018-12-01 00:00:00

abstract：:Bone marrow mesenchymal stem cells (BMSC) can ameliorate ischemic injury of various tissues. However, the molecular mechanisms involved remain to be clarified. In this study, we intend to investigate the effects of BMSC-derived conditioned medium (BMSC-CM) on hypoxia/reoxygenation (H/R)-induced injury of H9c2 myocardi...

journal_title：Journal of cellular physiology

authors： Li X,Xie X,Yu Z,Chen Y,Qu G,Yu H,Luo B,Lei Y,Li Y

更新日期：2019-08-01 00:00:00

abstract：:This study was to explore a potential role of epithelium-derived cytokines in Th17 differentiation. Th17 induction was evaluated by murine CD4(+) T cells treated with different combinations of five inducing cytokines, or conditioned media of human corneal epithelial cells (HCECs) exposed to a variety of stimuli. Th17 ...

journal_title：Journal of cellular physiology

authors： Zheng X,Bian F,Ma P,De Paiva CS,Stern M,Pflugfelder SC,Li DQ

更新日期：2010-01-01 00:00:00

abstract：:An isoform of the Na(+)/Ca(2+) exchanger (SDNCX1.10) was cloned from mesangial cells of Sprague-Dawley rat. Regulation of this isoform was compared to two other clones that were derived from the Dahl/Rapp salt sensitive (SNCX) and salt resistant rat (RNCX). All isoforms differ at the alternative splice site and at ami...

journal_title：Journal of cellular physiology

authors： Williams I,Williams C,Siroky B,Bates E,Kovacs G,Peti-Peterdi J,Unlap MT,Bell PD

更新日期：2004-05-01 00:00:00

abstract：:We previously demonstrated that, in the MC615 cartilage cell line, the p38/NF-kB pathway is activated both during differentiation and in response to an inflammatory stimulus. In both cases, the p38/NF-kB pathway activation leads to the expression of the lipocalin SIP24 and of COX-2. Given the fact that, in the same ce...

journal_title：Journal of cellular physiology

authors： Ulivi V,Cancedda R,Cancedda FD

更新日期：2008-11-01 00:00:00

abstract：:Reactivation of dormant chick erythrocyte (CE) nuclei was studied by fusing chick red cells with rat myoblasts, HeLa cells, and chick fibroblasts. Heterokaryons representing different stages of nuclear reactivation were fixed and examined for nuclear antigens using polyclonal patient autoantisera reacting with mammali...

journal_title：Journal of cellular physiology

authors： Nyman U,Lanfranchi G,Bergman M,Ringertz NR

更新日期：1984-08-01 00:00:00

abstract：:Core binding factor β (Cbfβ) is a partner protein of Runx family transcription factors with minimally characterized function in cartilage. Here we address the role of Cbfβ in cartilage by generating chondrocyte-specific Cbfβ-deficient mice (Cbfb(Δch/Δch) ) from Cbfb-floxed mice crossed with mice expressing Cre from th...

journal_title：Journal of cellular physiology

authors： Park NR,Lim KE,Han MS,Che X,Park CY,Kim JE,Taniuchi I,Bae SC,Choi JY

更新日期：2016-01-01 00:00:00

abstract：:Stem cells are a unique class of cells that are capable of self-renewal and differentiation into multiple lineages. An increasing number of studies have suggested that both embryonic and adult stem cells possess primary cilia, antenna-like structures protruding from cell surfaces that are critical for sensing and tran...

journal_title：Journal of cellular physiology

authors： Lyu R,Zhou J

更新日期：2017-05-01 00:00:00

abstract：:The endocannabinoid system (ECS) is activated at the onset of obesity and diverse metabolic diseases. Endocannabinoids mediate their physiological and behavioral effects by activating specific cannabinoid receptors, mainly cannabinoid receptor 1 (CB(1)R). Diabetic nephropathy (DN) is induced by hyperlipidemia, and ren...

journal_title：Journal of cellular physiology

authors： Lim JC,Lim SK,Han HJ,Park SH

更新日期：2010-11-01 00:00:00

abstract：:Treatment of CEM-C7 cells with glucocorticoids produces a 2.5-fold increase in the activity of the enzyme glutamine synthetase (GS). This increase is specific for steroids with glucocorticoid activity adn occurs over a range of steroid concentrations consistent with a receptor-mediated mechanism. Half-maximal and maxi...

journal_title：Journal of cellular physiology

authors： Harmon JM,Thompson EB

更新日期：1982-02-01 00:00:00

abstract：:The differentiation of human keratinocytes in most culture systems is incomplete; e.g., lamellar bodies, the characteristic lipid-delivery organelles of epidermis, are not present. Moreover, their lipid profile does not reflect the distinctive composition found in cornifying epidermis. In contrast, keratinocytes that ...

journal_title：Journal of cellular physiology

authors： Williams ML,Brown BE,Monger DJ,Grayson S,Elias PM

更新日期：1988-07-01 00:00:00

abstract：:An unusual inward current which is slowly elicited in the Xenopus oocyte membrane during sustained depolarization is reportedly carried by Na+. It is thought that Na+ selective channels are in some way induced to become voltage-sensitive by the depolarization. Earlier studies report that the induction process involves...

journal_title：Journal of cellular physiology

authors： Charpentier G,Kado RT

更新日期：1999-02-01 00:00:00

abstract：:Serine racemase (SR) is responsible for the biosynthesis of D-serine (D-Ser), an endogenous co-agonist for the glycine (Gly)-binding site on N-methyl-D-aspartate (NMDA) receptors, from L-Ser in the brain. We have previously demonstrated high expression of SR by chondrocytes in cartilage. In this study, we attempted to...

journal_title：Journal of cellular physiology

authors： Takarada T,Takahata Y,Iemata M,Hinoi E,Uno K,Hirai T,Yamamoto T,Yoneda Y

更新日期：2009-09-01 00:00:00

abstract：:Copper, an essential trace element, can be toxic to some cells when present in excess. But thorough investigations into the cytotoxicity of copper and subsequent molecular mechanisms are rare, although the cytotoxicity of copper has been applied to cancer chemotherapy. The present study demonstrates that Cu(2+) inhibi...

journal_title：Journal of cellular physiology

authors： Zhai Q,Ji H,Zheng Z,Yu X,Sun L,Liu X

更新日期：2000-08-01 00:00:00

abstract：:Thymosin β4 (Tβ4), a G-actin-sequestering secreted peptide, improves neurovascular remodeling and central nervous system plasticity, which leads to neurological recovery in many neurological diseases. Inflammatory response adjustment and tissue inflammation consequences from neurological injury are vital for neurologi...

journal_title：Journal of cellular physiology

authors： Shomali N,Baradaran B,Deljavanghodrati M,Akbari M,Hemmatzadeh M,Mohammadi H,Jang Y,Xu H,Sandoghchian Shotorbani S

更新日期：2020-04-01 00:00:00

abstract：:Terminal deoxynucleotidyl transferase (TdT) is a template-independent DNA polymerase that is transiently expressed during the normal development of T and B lymphocytes. Phorbol 12-myristate 13-acetate (PMA) has been reported to induce maturation-like changes, including the loss of TdT, in many leukemic cell lines. We ...

journal_title：Journal of cellular physiology

authors： Beland JL,Yuille MA,Hugunin M,Zhang XM,Silverstone AE

更新日期：1990-03-01 00:00:00

abstract：:Characteristic features like self-renewal, multilineage differentiation potential, and immune-modulatory/anti-inflammatory properties, besides the ability to mobilize and home distant tissues make stem cells (SCs) a lifeline for an individual. Stem cells (SCs) if could be harvested and expanded without any abnormal ch...

journal_title：Journal of cellular physiology

authors： Gugjoo MB,Amarpal,Fazili MR,Shah RA,Sharma GT

更新日期：2019-06-01 00:00:00

abstract：:The actin- and myosin-binding protein, caldesmon (CaD) is an essential component of the cytoskeleton in smooth muscle and non-muscle cells and is involved in the regulation of cell contractility, division, and assembly of actin filaments. CaD is abundantly present in endothelial cells (EC); however, the contribution o...

journal_title：Journal of cellular physiology

authors： Mirzapoiazova T,Kolosova IA,Romer L,Garcia JG,Verin AD

更新日期：2005-06-01 00:00:00

abstract：:The development of atherosclerotic plaque is associated with neovascularization in the thickened intima and media of vascular walls. Neovascularization may have a role in the progression of atherosclerotic plaque as well as in the development of intraplaque hemorrhage. However, the mechanism and stimulus for neovascul...

journal_title：Journal of cellular physiology

authors： Kuzuya M,Satake S,Esaki T,Yamada K,Hayashi T,Naito M,Asai K,Iguchi A

更新日期：1995-09-01 00:00:00

abstract：:As a natural metabolite of limonoids from Dictamnus dasycarpus, fraxinellone has been reported to be neuroprotective and anti-inflammatory. However, its influence on cellular metabolism remains largely unknown. In the present study, we investigated the effect of fraxinellone on cellular senescence-induced by oxidative...

journal_title：Journal of cellular physiology

authors： Han X,Chen H,Zhou J,Tai H,Gong H,Wang X,Huang N,Qin J,Fang T,Wang F,Xiao H

更新日期：2018-05-01 00:00:00

abstract：:Glutathione S-transferases (GSTs) are enzymes that are involved in the detoxification of harmful electrophilic endogenous and exogenous compounds by conjugating with glutathione (GSH). The liver fluke GSTs have multifunctional roles in the host-parasite interaction, such as general detoxification and bile acid sequest...

journal_title：Journal of cellular physiology

authors： Kalita J,Shukla R,Tripathi T

更新日期：2019-04-01 00:00:00

abstract：:Migration and proliferation of smooth muscle cells (SMCs) are key events during neointimal formation in pathological conditions of vessels. Tenascin-C (TNC) is upregulated in the developing neointima of lesions. We evaluated the effects of TNC on responses of SMCs against platelet-derived growth factor (PDGF) stimulat...

journal_title：Journal of cellular physiology

authors： Ishigaki T,Imanaka-Yoshida K,Shimojo N,Matsushima S,Taki W,Yoshida T

更新日期：2011-10-01 00:00:00

abstract：:Recently improved culture conditions for human adult arterial endothelial and smooth muscle cells from a wide variety of donors have been used to study the effects of lipoproteins on proliferation of both cell types in low serum culture medium. Optimal growth of endothelial and smooth muscle cells in an optimal nutrie...

journal_title：Journal of cellular physiology

authors： Chen JK,Hoshi H,McClure DB,McKeehan WL

更新日期：1986-11-01 00:00:00

abstract：:In vitro bioluminescence components of the dinoflagellates Gonyaulax polyedra, G. tamarensis, Dissodinium lunual, and Pyrocystis noctiluca were studied. The luciferases and luciferins of the four species cross-react in all combinations. All of these species possess high-molecular weight luciferases (200,000-400,000 da...

journal_title：Journal of cellular physiology

authors： Schmitter RE,Njus D,Sulzman FM,Gooch VD,Hastings JW

更新日期：1976-01-01 00:00:00