Induction of angiogenesis by smooth muscle cell-derived factor: possible role in neovascularization in atherosclerotic plaque.

abstract：:Previous studies demonstrated that overexpression of the type-1 insulin-like growth factor (IGF) receptor (IGF-1R) in skeletal myogenic cell lines increased proliferation and differentiation responses to IGF. However, it was unclear if such manipulations in primary, untransformed skeletal myogenic cells would result i...

journal_title：Journal of cellular physiology

authors： Quinn LS,Haugk KL

更新日期：1996-07-01 00:00:00

abstract：:Mouse epidermal cells can be grown as a proliferating monolayer in medium containing 0.02-0.1 mM calcium. Terminal differentiation of these cells with formation of cornified cells and cell death is induced by elevating calcium in the medium to greater than 0.1 mM. A variety of agents were studied as potential modifier...

journal_title：Journal of cellular physiology

authors： Hennings H,Holbrook KA,Yuspa SH

更新日期：1983-09-01 00:00:00

abstract：:Transforming growth factor-beta (TGFbeta) controls expression of plasminogen activator inhibitor type 1 (PAI-1), which regulates degradation of extracellular matrix proteins in fibrotic diseases. The TGFbeta receptor-specific Smad 3 has been implicated in the PAI-1 expression. The mechanism by which non-Smad signaling...

journal_title：Journal of cellular physiology

authors： Das F,Ghosh-Choudhury N,Venkatesan B,Li X,Mahimainathan L,Choudhury GG

更新日期：2008-02-01 00:00:00

abstract：:In vitro generation of HSCs from pluripotent stem cells (PSCs) can be regarded as novel therapeutic approaches for replacing bone marrow (BM) transplantation without immune rejection or graft versus host disease(GVHD). To date, many differentiation approaches have been evaluated in terms of directing PSCs toward diffe...

journal_title：Journal of cellular physiology

authors： Shan W,Wang B,Xu Y,Li X,Li X,Wang H,Lin Y,Tie R,Zhao Q,Wang J,Zheng W,Hu Y,Shi J,Yu X,Huang H

更新日期：2018-01-31 00:00:00

abstract：:Cdk9/Cyclin T1 complex is very important in controlling specific differentiative pathways of several cell types. Limited data are available regarding the expression of Cdk9/Cyclin T1 in hematopoietic and lymphoid tissues. Cdk9/Cyclin T1 expression seems to be related to particular stages of lymphoid differentiation/ac...

journal_title：Journal of cellular physiology

authors： De Falco G,Leucci E,Onnis A,Bellan C,Tigli C,Wirths S,Cerino G,Cocco M,Crupi D,De Luca A,Lanzavecchia A,Tosi P,Leoncini L,Giordano A

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Surgical stress has been suggested to facilitate colon cancer growth and metastasis. However, the precise mechanisms by which surgical trauma promotes colon cancer progression remain poorly understood. METHODS:To unravel the mechanisms underlying surgery-induced colon cancer progression, a syngenic transpla...

journal_title：Journal of cellular physiology

authors： Sun Z,Du C,Xu P,Miao C

更新日期：2019-04-01 00:00:00

abstract：:Protein-DNA interactions within the promoter of a cell cycle-regulated human H4 histone gene were examined by binding of 5'-end-labeled DNA segments to Western blots of nuclear protein fractions. Specific protein interactions were observed with DNA segments located between -500 bp and -1,070 bp upstream of the ATG ini...

journal_title：Journal of cellular physiology

authors： Pauli U,Chiu JF,Ditullio P,Kroeger P,Shalhoub V,Rowe T,Stein G,Stein J

更新日期：1989-05-01 00:00:00

abstract：:The opossum kidney (OK) cell was used as a model to test the hypothesis that estrogen directly affects proximal renal tubular epithelial cells. To demonstrate the expression of estrogen receptor in OK cells, we developed an approach using reverse transcription and the polymerase chain reaction. Analysis of the DNA amp...

journal_title：Journal of cellular physiology

authors： Stock JL,Coderre JA,Burke EM,Danner DB,Chipman SD,Shapiro JR

更新日期：1992-03-01 00:00:00

abstract：:Elevated levels of follistatin-like protein 1 (FSTL1) have been found both in mouse models for human rheumatoid arthritis (RA) and collagen-induced arthritis (CIA). In this study, we elucidated the potential mechanisms by which FSTL1 contributes to the pathogenesis of RA. Fibroblast-like synoviocytes (FLSs) were estab...

journal_title：Journal of cellular physiology

authors： Ni S,Li C,Xu N,Liu X,Wang W,Chen W,Wang Y,van Wijnen AJ

更新日期：2018-01-01 00:00:00

abstract：:Cancer cells in poorly vascularized solid tumors are constantly or intermittently exposed to stressful microenvironments, including glucose deprivation, hypoxia, and other forms of nutrient starvation. These tumor-specific conditions, especially glucose deprivation, activate a signaling pathway called the unfolded pro...

journal_title：Journal of cellular physiology

authors： Kim JY,Hwang JH,Cha MR,Yoon MY,Son ES,Tomida A,Ko B,Song SW,Shin-ya K,Hwang YI,Park HR

更新日期：2010-07-01 00:00:00

abstract：:The nuclear Ki-67 protein (pKi-67) has previously been shown to be exclusively expressed in proliferating cells. As a result, antibodies against this protein are widely used as prognostic tools in cancer diagnostics. Here we show, that despite the strong downregulation of pKi-67 expression in non-proliferating cells, ...

journal_title：Journal of cellular physiology

authors： Bullwinkel J,Baron-Lühr B,Lüdemann A,Wohlenberg C,Gerdes J,Scholzen T

更新日期：2006-03-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is one of the main liver diseases today, and may progress to steatohepatitis, cirrhosis, and hepatocellular carcinoma. Some studies have shown the beneficial effects of aerobic exercise on reversing NAFLD. To verify whether chronic aerobic exercise improves the insulin resistan...

journal_title：Journal of cellular physiology

authors： Batatinha HA,Lima EA,Teixeira AA,Souza CO,Biondo LA,Silveira LS,Lira FS,Rosa Neto JC

更新日期：2017-05-01 00:00:00

abstract：:The mechanisms by which mature myeloid cells are released from the bone marrow into the peripheral blood are not clearly understood. Glycosylation is likely to play an important role, as has been shown in the homing of lymphocytes to lymph nodes and of neutrophils to inflamed endothelia. Cell surface sialylation is an...

journal_title：Journal of cellular physiology

authors： Le Marer N,Skacel PO

更新日期：1999-06-01 00:00:00

abstract：:The influence upon different cellular and humoral parameters of hemopoiesis of three structurally unrelated, highly purified bacterial cell-wall components (BCWC) was investigated. The spleens of C57BL/6 mice assayed 6 days after the injection of either lipid A or outer-membrane lipoportein, but not murein, showed a m...

journal_title：Journal of cellular physiology

authors： Staber FG,Johnson GR

更新日期：1980-10-01 00:00:00

abstract：:Chemotherapy resistance is the major issue of choriocarcinoma. Apoptosis always is the ultimate outcome of chemotherapeutic drugs, which considered one of the reasons of resistance. We investigated the role of STAT3/NFIL3 signaling-inhibited apoptosis in chemotherapy resistance and whether Raddeanin A (RA) could be a ...

journal_title：Journal of cellular physiology

authors： Peng Z,Zhang C,Zhou W,Wu C,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：:Lithium has been used or explored to treat psychiatric and neurodegenerative diseases that are frequently associated with an abnormal immune status. It is likely that lithium may work through modulation of immune responses in these patients. Because dendritic cells (DC) play a central role in regulating immune respons...

journal_title：Journal of cellular physiology

authors： Liu KJ,Lee YL,Yang YY,Shih NY,Ho CC,Wu YC,Huang TS,Huang MC,Liu HC,Shen WW,Leu SJ

更新日期：2011-02-01 00:00:00

abstract：:The aim of the yearly National Congress of the Italian Society of Virology (SIV) is to promote the discussion between senior and younger researchers to improve the knowledge and scientific collaboration among the various areas of Virology. The invited and selected lecturers of the fourth National Congress of SIV cover...

journal_title：Journal of cellular physiology

authors： Salata C,Parolin C,Palù G

更新日期：2005-09-01 00:00:00

abstract：:We have previously shown that knockout of fibroblast growth factor-2 (FGF-2) and potential compensatory effects of other growth factors result in amelioration of disease symptoms in a transgenic mouse model of amyotrophic lateral sclerosis (ALS). ALS is a rapidly progressive neurological disorder leading to degenerati...

journal_title：Journal of cellular physiology

authors： Kefalakes E,Böselt S,Sarikidi A,Ettcheto M,Bursch F,Naujock M,Stanslowsky N,Schmuck M,Barenys M,Wegner F,Grothe C,Petri S

更新日期：2019-05-01 00:00:00

abstract：:Long suspected, recently recognized, and increasingly studied, non protein-coding RNAs (ncRNAs) are emerging as key drivers of biological control and pathology. Since their discovery in 1993, microRNAs (miRNAs) have been the subject of intense research focus and investigations have revealed striking findings, establis...

journal_title：Journal of cellular physiology

authors： Tye CE,Gordon JA,Martin-Buley LA,Stein JL,Lian JB,Stein GS

更新日期：2015-03-01 00:00:00

abstract：:New compounds with promising antidiabetic activity were synthesized. For the first time, a portion of the glibenclamide molecule was bound to a part of the core structure of thiazolidinedione to evaluate insulin secretagogue activity. Following studies in our laboratory, 4-{2-[2-(3,4-dichlorophenyl)-4-oxo-1,3-thiazoli...

journal_title：Journal of cellular physiology

authors： Mendes CP,Postal BG,Oliveira GTC,Castro AJG,Frederico MJS,Moraes ALL,Neuenfeldt PD,Nunes RJ,Menegaz D,Silva FRMB

更新日期：2018-01-01 00:00:00

abstract：:Cellular growth has been found to be directly related to the amount of sodium pumping activity in mouse lymphoblasts (L5178-Y) cultured in varying concentrations of the cardiac glycoside, ouabain. No short-term adaptation (within one generation) occured; i.e., neither growth rate nor (Na+ + K+)-ATPase activity increas...

journal_title：Journal of cellular physiology

authors： Shank BB,Smith NE

更新日期：1976-03-01 00:00:00

abstract：:Derivation of insulin producing cells (IPCs) from embryonic stem (ES) cells provides a potentially innovative form of treatment for type 1 diabetes. Here, we discuss the current state of the art, unique challenges, and future directions on generating IPCs. ...

journal_title：Journal of cellular physiology

authors： Raikwar SP,Zavazava N

更新日期：2009-02-01 00:00:00

abstract：:Estrogen has been shown to protect osteoblastic cells from apoptosis. Similarly, estrogen treatment preceding heat shock elevates heat shock protein 27 (hsp27) expression and increases thermoresistance in the murine estrogen receptor-transformed SMER14 osteoblastic cell line. Forced expression of hsp27 expression in o...

journal_title：Journal of cellular physiology

authors： Cooper LF,Tiffee JC,Griffin JP,Hamano H,Guo Z

更新日期：2000-12-01 00:00:00

abstract：:Although the role of several protooncogenes, including sis, myc, and myb in the regulation of growth and differentiation of vascular cells has been examined in some detail, limited information is available on the contribution of ras genes to these processes. In the present studies the influence of oncogenic ras transf...

journal_title：Journal of cellular physiology

authors： Sadhu DN,Lundberg MS,Burghardt RC,Ramos KS

更新日期：1994-12-01 00:00:00

abstract：:CRSBP-1 (mammalian LYVE-1) is a membrane glycoprotein highly expressed in lymphatic endothelial cells (LECs). It has multiple ligands, including hyaluronic acid (HA) and growth factors/cytokines (e.g., PDGF-BB and VEGF-A) containing CRS motifs (clusters of basic amino-acid residues). The ligand binding activities are ...

journal_title：Journal of cellular physiology

authors： Huang SS,Li YW,Wu JL,Johnson FE,Huang JS

更新日期：2018-04-01 00:00:00

abstract：:There is strong evidence that thyroid hormones through triiodothyronine (T3) regulate Sertoli cell proliferation and differentiation in the neonatal testis. However, the mechanism(s) by which they are able to control Sertoli cell proliferation is unclear. In the present study in vivo approaches (PTU-induced neonatal h...

journal_title：Journal of cellular physiology

authors： Gilleron J,Nebout M,Scarabelli L,Senegas-Balas F,Palmero S,Segretain D,Pointis G

更新日期：2006-10-01 00:00:00

abstract：:Neuronal activity-dependent gene transcription is a key feature of long-lasting synaptic strengthening associated with learning and memory, as well as activity-dependent neuroprotection. To comprehensively determine the molecular alterations, we carried out genome-wide microarray analysis in cultured rat cortical neur...

journal_title：Journal of cellular physiology

authors： Xiang G,Pan L,Xing W,Zhang L,Huang L,Yu J,Zhang R,Wu J,Cheng J,Zhou Y

更新日期：2007-07-01 00:00:00

abstract：:Macrophages are heterogeneous and their phenotype and functions are regulated by the surrounding micro-environment. Macrophages commonly exist in two distinct subsets: 1) Classically activated or M1 macrophages, which are pro-inflammatory and polarized by lipopolysaccharide (LPS) either alone or in association with Th...

journal_title：Journal of cellular physiology

authors： Shapouri-Moghaddam A,Mohammadian S,Vazini H,Taghadosi M,Esmaeili SA,Mardani F,Seifi B,Mohammadi A,Afshari JT,Sahebkar A

更新日期：2018-09-01 00:00:00

abstract：:Maintenance of beta1 integrin-mediated cell adhesion in quiescent human mammary epithelial (HME) cells requires protein phosphatase (PP) 2A for not only dephosphorylation of beta1 integrin but also recruitment of IQGAP1 to Rac-bound beta1 integrin. However, how PP2A-dependent regulatory machinery of cell adhesion resp...

journal_title：Journal of cellular physiology

authors： Takahashi K,Suzuki K

更新日期：2006-07-01 00:00:00

abstract：:We have partially purified a mitogenic factor, termed colony stimulating factor, which is secreted from a human T lymphocytic cell line, and which stimulates in vitro formation of colonies of macrophages and granulocytes by human bone marrow cells. Colony stimulating factor (CSF) produced by cells grown in serum suppl...

journal_title：Journal of cellular physiology

authors： Frölich M

更新日期：1981-12-01 00:00:00