Generation of hematopoietic cells from mouse pluripotent stem cells in a 3D culture system of self-assembling peptide hydrogel.

abstract：:Chemokines play an important role in regulating the complex immune system at the maternal-fetal interface during pregnancy. Among various chemokines, CC motif chemokine ligand 2 (CCL2) plays a role in the recruitment of immune regulatory cells to implantation sites within the endometrium. In cattle, CCL2 is abundantl...

journal_title：Journal of cellular physiology

authors： Lim W,Bae H,Bazer FW,Kim SM,Song G

更新日期：2018-04-01 00:00:00

abstract：:Parathyroid hormone (PTH) greatly increased the level of adenosine 3', 5' cyclic monophosphate (cAMP) in rabbit costal chondrocytes in culture 2 minutes after its addition. PTH, as well as N6 O2' dibutyryl adenosine 3', 5' cyclic monophosphate (DBcAMP) and 8 Bromo adenosine 3', 5' cyclic monophosphate (8 Br-cAMP) indu...

journal_title：Journal of cellular physiology

authors： Takigawa M,Takano T,Suzuki F

更新日期：1981-02-01 00:00:00

abstract：:Wnt/β-catenin signaling pathway plays a crucial role in diabetic cardiomyopathy (DCM), thus we aimed at investigating the effect of one therapeutic approach with resveratrol (RSV) given systemically and combined treatment of RSV with mesenchymal stem cells (MSCs) that was either RSV-preconditioned or not on Wnt/β-cate...

journal_title：Journal of cellular physiology

authors： ShamsEldeen AM,Ashour H,Shoukry HS,Fadel M,Kamar SS,Aabdelbaset M,Rashed LA,Ammar HI

更新日期：2019-07-01 00:00:00

abstract：:The biological effects of the Corticotropin-releasing factor (CRF) family of neuropeptides are mediated by mobilization of [Ca(2+)]. Aim of the current work was to examine if the calcineurin/NFAT (nuclear factor of activated T-cells) signaling pathway is involved in the effect of CRF peptides in catecholamine synthesi...

journal_title：Journal of cellular physiology

authors： Dermitzaki E,Tsatsanis C,Gravanis A,Margioris AN

更新日期：2012-05-01 00:00:00

abstract：:The caspase recruitment domain (CARD)-containing proteins CARMA1-3 share high degree of sequence, structure and functional homology. Whereas CARMA1 and CARMA3 have been identified as crucial components of signal transduction pathways that lead to activation of NF-κB transcription factor, little is known about the func...

journal_title：Journal of cellular physiology

authors： Scudiero I,Zotti T,Ferravante A,Vessichelli M,Vito P,Stilo R

更新日期：2011-12-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF), a potent mediator of endothelial proliferation and migration, has an important role also in brain edema formation during hypoxia and ischemia. VEGF binds to the tyrosine kinase receptors Flt-1 and Flk-1. Yet, their relative importance for hypoxia-induced hyperpermeability is ...

journal_title：Journal of cellular physiology

authors： Vogel C,Bauer A,Wiesnet M,Preissner KT,Schaper W,Marti HH,Fischer S

更新日期：2007-07-01 00:00:00

abstract：:The purpose of this study was to evaluate the anti-head and neck squamous cell carcinoma (anti-HNSCC) cell activity by C6 ceramide and multikinase inhibitor PKC412. Experiments were performed on HNSCC cell lines (SQ20B and SCC-9) and primary human oral carcinoma cells. Results showed that PKC412 inhibited HNSCC cell p...

journal_title：Journal of cellular physiology

authors： Zhu Y,Wang C,Zhou Y,Ma N,Zhou J

更新日期：2018-12-01 00:00:00

abstract：:Galectin-1 is reported to be upregulated in various human cancers. However, the relationship between galectin-1 expression and cancer prognosis has not been systematically assessed. In this study, we searched PubMed, Web of Science, and Embase to collect all relevant studies and a meta-analysis was performed. We found...

journal_title：Journal of cellular physiology

authors： Huang MY,He JP,Zhang WQ,Liu JL

更新日期：2019-08-01 00:00:00

abstract：:Spiral artery remodeling at the maternal-fetal interface is crucial for successful pregnancy and requires the interaction between the first trimester trophoblast and the endothelial cells of the maternal vessels. However, the precise mechanism of this dialog has yet to be determined. The current study investigated whe...

journal_title：Journal of cellular physiology

authors： Beltrame JS,Scotti L,Sordelli MS,Cañumil VA,Franchi AM,Parborell F,Ribeiro ML

更新日期：2019-05-01 00:00:00

abstract：:The effects of the glucose supply on growth and metabolism of an SP2/0 derived recombinant myeloma cell line were studied in chemostat culture during growth on IMDM medium at a fixed dilution rate of 0.032 h-1. Lowering of the feed medium glucose concentration from 25.0 to 1.4 mmol/L resulted in a decrease of steady-s...

journal_title：Journal of cellular physiology

authors： Meijer JJ,van Dijken JP

更新日期：1995-02-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) cells are characterised by their extreme chemoresistance. The activity of multiple-drug resistance (MDR) transporters that extrude antitumor drugs from cells plays the most important role in this phenomenon. To date, the mechanism controlling the expression and activity of MDR transporter...

journal_title：Journal of cellular physiology

authors： Quezada C,Garrido W,Oyarzún C,Fernández K,Segura R,Melo R,Casanello P,Sobrevia L,San Martín R

更新日期：2013-03-01 00:00:00

abstract：:Ubiquitin-specific protease 14 (USP14) is a ubiquitin-specific protease that is associated with the proteasome and plays important roles in cellular functions, viral infection, inflammatory responses, neurodegenerative diseases, and tumorigenesis. USP14 appears to have a dual function in regulating intracellular prote...

journal_title：Journal of cellular physiology

authors： Wang D,Ma H,Zhao Y,Zhao J

更新日期：2020-11-01 00:00:00

abstract：:Autocrine activation of the epidermal growth factor (EGF) receptor on keratinocytes has been recognized as an important growth regulatory mechanism involved in epithelial homeostasis, and, possibly, hyperproliferative diseases. Insulin-like growth factor (IGF)-1 and insulin have been shown to be paracrine keratinocyte...

journal_title：Journal of cellular physiology

authors： Vardy DA,Kari C,Lazarus GS,Jensen PJ,Zilberstein A,Plowman GD,Rodeck U

更新日期：1995-05-01 00:00:00

abstract：:CRM197 is a naturally nontoxic diphtheria toxin mutant that binds and inhibits heparin-binding epidermal growth factor-like growth factor. CRM197 serves as carrier protein for vaccine and other therapeutic agents. CRM197 also inhibits the growth, migration, invasion, and induces apoptosis in various tumors. Vascular c...

journal_title：Journal of cellular physiology

authors： Hu Y,Lin X,Wang P,Xue YX,Li Z,Liu LB,Yu B,Feng TD,Liu YH

更新日期：2015-08-01 00:00:00

abstract：:Preincubation of human neutrophils with phorbol esters or soluble diglycerides enhances subsequent f-Met-Leu-Phe (fMLP)-stimulated arachidonate mobilization and leukotriene B4 (LTB4) synthesis. We have recently reported that 1,3-dioctanoylglycerol (1,3-diC8) is equipotent with 1,2-sn-dioctanoylglycerol (1,2-diC8) as p...

journal_title：Journal of cellular physiology

authors： Rosenthal MD,Franson RC

更新日期：1994-09-01 00:00:00

abstract：:Osteopontin (OPN) is a major non-collagenous bone matrix protein implicated in the regulation of cell function. Although OPN is rich in the cementum of the tooth, the significance of OPN in this tissue is not understood. Tooth root resorption is the most frequent complication of orthodontic tooth movement (TM). The ob...

journal_title：Journal of cellular physiology

authors： Chung CJ,Soma K,Rittling SR,Denhardt DT,Hayata T,Nakashima K,Ezura Y,Noda M

更新日期：2008-03-01 00:00:00

abstract：:Cultured preadipose 3T3 cells undergo a process of differentiation in which they convert to adipose cells. Growth hormone promotes this conversion. Since 3T3 sublines vary in their susceptibility to adipose conversion, it was of interest to examine the properties of the growth hormone receptors in relation to that sus...

journal_title：Journal of cellular physiology

authors： Nixon T,Green H

更新日期：1983-06-01 00:00:00

abstract：:Ankylosing spondylitis (AS) is a chronic immune-mediated inflammatory disease that affects both axial and peripheral skeletons as well as soft tissues. Recent investigations offer that disease pathogenesis is ascribed to a complex interplay of genetic, environmental, and immunological factors. Until now, there is no a...

journal_title：Journal of cellular physiology

authors： Mohammadi H,Hemmatzadeh M,Babaie F,Gowhari Shabgah A,Azizi G,Hosseini F,Majidi J,Baradaran B

更新日期：2018-08-01 00:00:00

abstract：:The single-copy gene of human basic fibroblast growth factor (bFGF) encodes four co-expressed isoforms, with an apparent molecular weight (M(r)) of 24 kD, 22.5 kD, 22 kD, and 18 kD, co-translated from a single mRNA. As a tool for the study of the role exerted by the different bFGF isoforms in the biology of endothelia...

journal_title：Journal of cellular physiology

authors： Gualandris A,Urbinati C,Rusnati M,Ziche M,Presta M

更新日期：1994-10-01 00:00:00

abstract：:Cyclosporine A (CyA) is a powerful nonsteroidal immunosuppressive agent used to prevent graft rejection of organ and bone marrow transplants. A major side effect observed can be attributed to the fibroblast and its functions: proliferation of fibroblasts and formation of fibrotic tissue in the gingiva (fibrous hyperpl...

journal_title：Journal of cellular physiology

authors： Willershausen-Zönnchen B,Lemmen C,Schumacher U

更新日期：1992-08-01 00:00:00

abstract：:As a natural metabolite of limonoids from Dictamnus dasycarpus, fraxinellone has been reported to be neuroprotective and anti-inflammatory. However, its influence on cellular metabolism remains largely unknown. In the present study, we investigated the effect of fraxinellone on cellular senescence-induced by oxidative...

journal_title：Journal of cellular physiology

authors： Han X,Chen H,Zhou J,Tai H,Gong H,Wang X,Huang N,Qin J,Fang T,Wang F,Xiao H

更新日期：2018-05-01 00:00:00

abstract：:The human chronic myeloid leukemia cell line K562 acquires several megakaryoblastoid features when cultured in the presence of the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). We observed strongly increased secretion of several proteins into the culture media of K562 cells within a few hours of TPA trea...

journal_title：Journal of cellular physiology

authors： Alitalo R,Andersson LC,Tapiovaara H,Sistonen L,Vaheri A,Stephens R

更新日期：1989-07-01 00:00:00

abstract：:The process of induction of human malignant T-lymphoblastic cell line MOLT-3 by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) was examined. It was found that the induction process by TPA, which included increase in cells with receptors to sheep red blood cells (E--rosette positive--E+) and decrease in t...

journal_title：Journal of cellular physiology

authors： Nagasawa K,Howatson A,Mak TW

更新日期：1981-10-01 00:00:00

abstract：:Cervical cancer is the fourth most frequent cancer in women worldwide. PDZ-binding kinase (PBK) is proven to promote the malignant behaviors of various carcinomas. However, its functional roles and oncogenic mechanisms in cervical cancer are poorly understood. In this study, we reported that PBK was highly expressed i...

journal_title：Journal of cellular physiology

authors： Ma H,Han F,Yan X,Qi G,Li Y,Li R,Yan S,Yuan C,Song K,Kong B

更新日期：2020-11-13 00:00:00

abstract：:alpha-Crystallins share structural and functional properties with the stress protein hsp27. These polypeptides are expressed at low constitutive levels in many tissues including brain, and alpha B-crystallin and hsp27 can accumulate in central nervous system glia in a variety of neurological conditions. We report here...

journal_title：Journal of cellular physiology

authors： Head MW,Corbin E,Goldman JE

更新日期：1994-04-01 00:00:00

abstract：:Autophagy is an evolutionarily conserved intracellular process and is considered one of the main catabolism pathways. In the process of autophagy, cells are digested nonselectively or selectively to recover nutrients and energy, so it is regarded as an antiaging process. In addition to the essential role of autophagy ...

journal_title：Journal of cellular physiology

authors： Guo YF,Su T,Yang M,Li CJ,Guo Q,Xiao Y,Huang Y,Liu Y,Luo XH

更新日期：2021-01-16 00:00:00

abstract：:The herbicide 2,4,5 trichlorophenoxy acetic acid (245T) at concentrations from 0.5 to 0.9 mM, was found to inhibit respiration and then growth in exponentially growing cultures of Tetrahymena pyriformis. Cell division was stopped for periods up to 60 minutes after which the cells recovered and division resumed. Recove...

journal_title：Journal of cellular physiology

authors： Silberstein GB,Hooper AB

更新日期：1975-04-01 00:00:00

abstract：:Sleep-disordered breathing with recurrent apnea (periodic cessation of breathing) results in chronic intermittent hypoxia (IH), which leads to cardiovascular and respiratory pathology. Molecular mechanisms underlying IH-evoked cardio-respiratory co-morbidities have not been delineated. Mice with heterozygous deficienc...

journal_title：Journal of cellular physiology

authors： Yuan G,Nanduri J,Khan S,Semenza GL,Prabhakar NR

更新日期：2008-12-01 00:00:00

abstract：:Guanine nucleotides and pertussis toxin were used to test for the involvement of a guanine nucleotide binding protein in the vasopressin V1 receptor-mediated stimulation of protein kinase C activity in Swiss 3T3 cells. Addition of vasopressin in the presence of [gamma-32P]ATP and digitonin caused a marked and rapid in...

journal_title：Journal of cellular physiology

authors： Erusalimsky JD,Rozengurt E

更新日期：1989-11-01 00:00:00

abstract：:Induction of apoptosis has been associated with a variety of exposures which result in inflammatory and fibrotic lung disorders. Macrophages are key regulatory cells in the lung; however, the role of apoptotic macrophages in those pulmonary disorders is not well characterized. In the present investigation, apoptotic m...

journal_title：Journal of cellular physiology

authors： Wang L,Antonini JM,Rojanasakul Y,Castranova V,Scabilloni JF,Mercer RR

更新日期：2003-02-01 00:00:00