Ubiquitin-specific protease 14 is a new therapeutic target for the treatment of diseases.

abstract：:Parathyroid hormone-related protein (PTHrP) (107-139), in contrast to the N-terminal fragment PTHrP (1-36), has been shown to interact with the vascular endothelial growth factor (VEGF) system to modulate human osteoblast differentiation. In this study, we evaluated whether this interaction might affect human osteobla...

journal_title：Journal of cellular physiology

authors： Alonso V,de Gortázar AR,Ardura JA,Andrade-Zapata I,Alvarez-Arroyo MV,Esbrit P

更新日期：2008-12-01 00:00:00

abstract：:Breast cancer, as the most common cancer in women which affects patients both mentally and physically, requires great attention in many areas and many levels as this cancer is known to be multifactorial. Single-stranded molecules called microRNAs with near 22 nucleotides are seen to act in central dogma of molecular b...

journal_title：Journal of cellular physiology

authors： Bahreini F,Rayzan E,Rezaei N

更新日期：2021-03-01 00:00:00

abstract：:The effects of adenosine and two analogs, L-phenylisopropyladenosine (L-PIA) and 5'-N-ethylcarboxamidoadenosine (NECA), on cAMP production and on platelet-derived growth factor (PDGF)-stimulated initiation of DNA synthesis in growth-arrested cultures of rat arterial smooth muscle cells (SMC) were studied. The intracel...

journal_title：Journal of cellular physiology

authors： Jonzon B,Nilsson J,Fredholm BB

更新日期：1985-09-01 00:00:00

abstract：:To test the hypothesis that football training would be accompanied by physiological adaptations and hormonal changes, we analyzed the effects of a whole football season on physical fitness and hormonal concentrations in youth football players. Male football players (n = 29, age 16.51 ± 0.7 years) in a regional profess...

journal_title：Journal of cellular physiology

authors： Muscella A,Vetrugno C,Spedicato M,Stefàno E,Marsigliante S

更新日期：2019-11-01 00:00:00

abstract：:Progesterone is an endogenous immunomodulator and can suppress T-cell activation during pregnancy. We have previously shown that the non-genomic effects of progesterone, especially acidification, are exerted via plasma membrane sites and suppress cellular genomic responses to mitogens. This study aimed to show that ac...

journal_title：Journal of cellular physiology

authors： Chien EJ,Liao CF,Chang CP,Pu HF,Lu LM,Shie MC,Hsieh DJ,Hsu MT

更新日期：2007-05-01 00:00:00

abstract：:The human cervical cancer (CC) has been identified as one of the most common tumors in women, and the molecular regulation in CC still remains unclear. The dysregulation of periostin has been found in a variety of cancers, but whether it is involved in the regulation of CC is unknown. The present study aimed to invest...

journal_title：Journal of cellular physiology

authors： Han X,Wang Q,Wang Y,Hu B,Dong X,Zhang H,Wang W

更新日期：2019-08-01 00:00:00

abstract：:Cultured preadipose 3T3 cells are able to undergo a process of differentiation through which they are converted into adipose cells. Growth hormone induces this conversion in resting cultures but not in growing cultures. It was of interest to determine the period of cell sensitivity to the hormone and the timing of the...

journal_title：Journal of cellular physiology

authors： Morikawa M

更新日期：1986-08-01 00:00:00

abstract：:Optimal stimulation of signal transduction and biological functions by IGF-I in porcine smooth muscle cells (pSMC) requires ligand occupancy of the alphaVbeta3 integrin. Binding of heparin-binding domain (HBD) of vitronectin (VN) to the cysteine loop (C-loop) region of beta3 is required for pSMC to respond optimally t...

journal_title：Journal of cellular physiology

authors： Xi G,Maile LA,Yoo SE,Clemmons DR

更新日期：2008-02-01 00:00:00

abstract：:The C3H/10T 1/2 embryo cell line, which is nontumorigenic when inoculated subcutaneously in saline suspension, produces tumors when implanted subcutaneously attached to 1 X 5 X 10 mm plastic plates. Under these in vivo conditions there is direct selection for "spontaneous" transformants that have undergone the specifi...

journal_title：Journal of cellular physiology

authors： Paranjpe M,del Ande Eaton S,Boone CW

更新日期：1978-07-01 00:00:00

abstract：:miR-222 participates in many cardiovascular diseases, but its effect on cardiac remodeling induced by diabetes is unclear. This study evaluated the functional role of miR-222 in cardiac fibrosis in diabetic mice. Streptozotocin (STZ) was used to establish a type 1 diabetic mouse model. After 10 weeks of STZ injection,...

journal_title：Journal of cellular physiology

authors： Wang Z,Wang Z,Gao L,Xiao L,Yao R,Du B,Li Y,Wu L,Liang C,Huang Z,Li P,Zhang Y

更新日期：2020-03-01 00:00:00

abstract：:Mice of the C3H/HeJ strain exhibit low inflammatory and immunological responses to certain bacterial lipopolysaccharide (LPS) preparations. Lymphocytes from C3H/HeJ mice also show defective LPS-induced mitogenesis. We tested the colony stimulating activity (CSA) response of C3H/HeJ mice. As controls we used mice of th...

journal_title：Journal of cellular physiology

authors： Russo M,Lutton JD

更新日期：1977-08-01 00:00:00

abstract：:Nitric oxide triggers cGMP-dependent kinase-mediated phosphorylation of the actin regulator vasodilator-stimulated phosphoprotein (VASP) at residue serine239. The function of this phosphorylation for smooth muscle cell (SMC) adhesion, spreading, matrix contraction, and invasion is not well understood. We reconstituted...

journal_title：Journal of cellular physiology

authors： Defawe OD,Kim S,Chen L,Huang D,Kenagy RD,Renné T,Walter U,Daum G,Clowes AW

更新日期：2010-01-01 00:00:00

abstract：:DEAH box protein DHX33 has been found to be necessary for cell proliferation and early development of multicellular organisms. It plays diverse roles in regulating gene transcription, ribosome RNA synthesis, and protein translation. Dysregulation of DHX33 has been observed in various human cancers. In this study, we i...

journal_title：Journal of cellular physiology

authors： Su D,Yuan B,Su C,Zhang Y

更新日期：2019-01-26 00:00:00

abstract：:Metabolic network modeling of microbial communities provides an in-depth understanding of community-wide metabolic and regulatory processes. Compared to single organism analyses, community metabolic network modeling is more complex because it needs to account for interspecies interactions. To date, most approaches foc...

journal_title：Journal of cellular physiology

authors： Henry CS,Bernstein HC,Weisenhorn P,Taylor RC,Lee JY,Zucker J,Song HS

更新日期：2016-11-01 00:00:00

abstract：:The p53 protein directly regulates the expression of the WAF1 (wild-type p53-activated fragment 1) protein which is a cyclin-dependent kinase inhibitor (CDK1). DNA damaging agents such as ionizing or UV radiation, and some chemical agents induce WAF1 in wild-type p53 containing cells, thereby halting cell cycle progre...

journal_title：Journal of cellular physiology

authors： Shiohara M,Akashi M,Gombart AF,Yang R,Koeffler HP

更新日期：1996-03-01 00:00:00

abstract：:The cells responsible for the long-term in vitro generation of murine mast cells have been examined. Sequential analysis of all colony types obtained from cultures of spleen or bone marrow cells showed that only colonies derived from multipotential cells (mixed-erythroid colonies) or mast cell progenitors, contained c...

journal_title：Journal of cellular physiology

authors： Li CL,Johnson GR

更新日期：1984-10-01 00:00:00

abstract：:Clones of Chinese hamster ovary (CHO) cells were isolated by single-step selection for resistance to killing Concanavalin A (ConA) and certain cellular and membrane properties were examined. The ConA-resistant isolates were only about 2-fold more resistant than wild type cells to the selecting lectin, but exhibited pl...

journal_title：Journal of cellular physiology

authors： Cifone MA,Hynes RO,Baker RM

更新日期：1979-07-01 00:00:00

abstract：:Hemodynamic forces influence many endothelial cell functions. The coupling between hemodynamic forces and cell function could be mediated by mechano-sensitive ion channels present in the plasma membrane of endothelial cells. Because one of these channels is permeable to Ca2+, we tested whether hemodynamic forces influ...

journal_title：Journal of cellular physiology

authors： Oliver JA,Chase HS Jr

更新日期：1992-04-01 00:00:00

abstract：:The possibility that one or both of the synthetic triamines, 1,3,6-triaminohexane and 1,4,7-triaminoheptane, could substitute for the naturally occurring polyamines in the growth of SV-3T3 cells was investigated. It was found that these triamines did lead to a restoration of growth in cells in which spermidine content...

journal_title：Journal of cellular physiology

authors： McGovern KA,Clark RS,Pegg AE

更新日期：1986-05-01 00:00:00

abstract：:Transforming growth factor-beta (TGFbeta) controls expression of plasminogen activator inhibitor type 1 (PAI-1), which regulates degradation of extracellular matrix proteins in fibrotic diseases. The TGFbeta receptor-specific Smad 3 has been implicated in the PAI-1 expression. The mechanism by which non-Smad signaling...

journal_title：Journal of cellular physiology

authors： Das F,Ghosh-Choudhury N,Venkatesan B,Li X,Mahimainathan L,Choudhury GG

更新日期：2008-02-01 00:00:00

abstract：:The herbicide 2,4,5 trichlorophenoxy acetic acid (245T) at concentrations from 0.5 to 0.9 mM, was found to inhibit respiration and then growth in exponentially growing cultures of Tetrahymena pyriformis. Cell division was stopped for periods up to 60 minutes after which the cells recovered and division resumed. Recove...

journal_title：Journal of cellular physiology

authors： Silberstein GB,Hooper AB

更新日期：1975-04-01 00:00:00

abstract：:Previously, we found that hypoxia can deeply affect the production of cytokines in human peripheral mononuclear cells (PBMC). Here, we demonstrated that the cycle progression of hypoxic PBMC, cultured in the presence or not of a specific T cell activator such as phytohaemagglutinin (PHA), was delayed when compared wit...

journal_title：Journal of cellular physiology

authors： Naldini A,Carraro F

更新日期：1999-12-01 00:00:00

abstract：:The expression of parathyroid hormone-related protein (PTHrP) was studied in a range of cell cultures representative of the osteoblast lineage and in rat calvarial sections. Primary newborn rat calvarial cells, a rat preosteoblastic cell line (UMR 201), a mouse stromal cell line (ST 2), a mouse calvaria-derived osteob...

journal_title：Journal of cellular physiology

authors： Suda N,Gillespie MT,Traianedes K,Zhou H,Ho PW,Hards DK,Allan EH,Martin TJ,Moseley JM

更新日期：1996-01-01 00:00:00

abstract：:Previous studies have indicated that intracellular Ca2+ is involved in fetal bovine serum (FBS)- or growth factor (GF)-stimulated Na+ influx in human foreskin fibroblasts (HSWP). In the present study, 45Ca2+ efflux from serum-deprived HSWP cells was measured in response to 10% FBS or GF [lys-bradykinin, vasopressin, e...

journal_title：Journal of cellular physiology

authors： Owen NE,Villereal ML

更新日期：1983-10-01 00:00:00

abstract：:Wnt/β-catenin signaling pathway plays a crucial role in diabetic cardiomyopathy (DCM), thus we aimed at investigating the effect of one therapeutic approach with resveratrol (RSV) given systemically and combined treatment of RSV with mesenchymal stem cells (MSCs) that was either RSV-preconditioned or not on Wnt/β-cate...

journal_title：Journal of cellular physiology

authors： ShamsEldeen AM,Ashour H,Shoukry HS,Fadel M,Kamar SS,Aabdelbaset M,Rashed LA,Ammar HI

更新日期：2019-07-01 00:00:00

abstract：:Short term, carrier mediated transport of D-glucose, L-leucine and L-lysine by guinea pig peritoneal macrophages was characterized. Analysis of the amino acid transport demonstrated two-limbed double reciprocal plots suggesting two transport systems for each amino acid. The low concentration limb of the curves establi...

journal_title：Journal of cellular physiology

authors： Straus DC,Imhoff JG,Bonventre PF

更新日期：1977-10-01 00:00:00

abstract：:Studies were conducted to explore hormonal and nutritional factors that might be involved in the regulation of retinol-binding protein (RBP) synthesis and secretion by the liver. The studies employed primary cultures of hepatocytes from normal rats. When cells were cultured in Dulbecco's modified Eagle's medium alone,...

journal_title：Journal of cellular physiology

authors： Dixon JL,Goodman DS

更新日期：1987-01-01 00:00:00

abstract：:Human neutrophils labeled with chlortetracycline (CTC), commonly used as a probe of membrane-bound calcium, release lysosomal enzymes and exhibit a rapid decrease in fluorescence when exposed to the chemotactic peptide fMet-Leu-Phe or the lectin Con A. This decrease has been attributed to the release of calcium from a...

journal_title：Journal of cellular physiology

authors： Smolen JE,Noble P,Freed R,Weissmann G

更新日期：1983-12-01 00:00:00

abstract：:Ack1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. It integrates signals from plethora of ligand-activated receptor tyrosine kinases (RTKs), for example, MERTK, EGFR, HER2, PDGFR and insulin receptor to initiate intra...

journal_title：Journal of cellular physiology

authors： Mahajan K,Mahajan NP

更新日期：2010-08-01 00:00:00

abstract：:Relative to their normal counterparts, transformed epithelial cells have a distinctive and quantifiable three-dimensional shape. Biophysical and mathematical methods are used to distinguish these extremes in cells from two lines, cultured from rat liver and tracheal epithelium, respectively. Cells adopted a more trans...

journal_title：Journal of cellular physiology

authors： Heckman CA,Plummer HK 3rd,Runyeon CS

更新日期：1996-01-01 00:00:00