Polarity and motility of large polymer-actin complexes.

Abstract:

:The polarity of polymer-actin complexes obtained by mixing F-actin with synthetic polymers carrying positive charges such as poly(L-lysine), x,y-ionene bromide polymers, and poly(N-[3-(dimethylamino)propyl]acrylamide) (PDMAPAA-Q) have been investigated. Actin complexes formed with poly(L-lysine) and PDMAPAA-Q, which carry charges on their side chains, show a higher polarity than those formed with x,y-ionene bromide polymers, which have charges on their chain backbones. All these polymer-actin complex gels show motility on the surfaces coated with myosin by coupling to adenosine 5'-triphosphate hydrolysis. A linear correlation between the polarity of polymer-actin complex gels and the motility is observed.

journal_name

Biomacromolecules

journal_title

Biomacromolecules

authors

Kakugo A,Shikinaka K,Takekawa N,Sugimoto S,Osada Y,Gong JP

doi

10.1021/bm0494038

keywords:

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

845-9

issue

2

eissn

1525-7797

issn

1526-4602

journal_volume

6

pub_type

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