The roles of bone mineral density, bone turnover, and other properties in reducing fracture risk during antiresorptive therapy.

abstract：:Three case reports in this article illustrate the diagnostic methods used and the treatment course encountered for many patients with diabetic peripheral neuropathic pain (DPNP). Each case addresses an aspect of DPNP: pain that appears to be refractory to initial therapy, DPNP occurring with other medical conditions, ...

journal_title：Mayo Clinic proceedings

authors： Belgrade MJ,Cole BE,McCarberg BH,McLean MJ

更新日期：2006-04-01 00:00:00

abstract：:Vitamin K antagonists were the only class of oral anticoagulants available to clinicians for decades. However, with the US Food and Drug Administration approval of new oral anticoagulants, such as dabigatran, rivaroxaban, and apixaban, clinicians now have a broader choice. Given the recent approval and availability of...

journal_title：Mayo Clinic proceedings

authors： Gonsalves WI,Pruthi RK,Patnaik MM

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To describe the two variants of Castleman's disease--the hyaline-vascular type and the plasma-cell type--and discuss the associated histologic features. DESIGN:We present a case of the hyaline-vascular type and review the literature. RESULTS:Castleman's disease was once thought to be localized and self-limi...

journal_title：Mayo Clinic proceedings

authors： Shahidi H,Myers JL,Kvale PA

更新日期：1995-10-01 00:00:00

abstract：:The ventriculoatrial shunt (VAS) was developed to control hydrocephalic syndromes effectively. Several complications, however, have been described after the procedure. One of the most serious consequences is the development of severe pulmonary hypertension attributed to multiple and recurrent pulmonary embolization ca...

journal_title：Mayo Clinic proceedings

authors： Pascual JM,Prakash UB

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To assess whether amiodarone, as part of a strategy to achieve sinus rhythm, is safe and effective compared with a placebo or rate control drug in patients with persistent atrial fibrillation (AF) of more than 30 days' duration. METHODS:Randomized controlled trials comparing amiodarone with a placebo or rate...

journal_title：Mayo Clinic proceedings

authors： Doyle JF,Ho KM

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To examine the use of tests that measure ejection fraction (EF) and the use of coronary angiography among patients with an initial diagnosis of heart failure (HF). PATIENTS AND METHODS:All potential cases of incident HF in Olmsted County, Minnesota, between 1979 and 1999 were identifled. In a random sample o...

journal_title：Mayo Clinic proceedings

authors： Kurtz CE,Gerber Y,Weston SA,Redfield MM,Jacobsen SJ,Roger VL

更新日期：2006-07-01 00:00:00

abstract：:The platelets of a patient with the Bernard-Soulier syndrome were studied by electron microscopy. The main abnormalities were the presence of giant and often round platelets, hypertrophic and frequently widely dilated open canalicular system, disorganized microtubules, and platelets with sparse or absent granulation....

journal_title：Mayo Clinic proceedings

authors： Maldonado JE,Gilchrist GS,Brigden LP,Bowie EJ

更新日期：1975-07-01 00:00:00

abstract：:Millions of cigarette smokers require surgery each year. Those who quit smoking may reduce their risk of respiratory, cardiovascular, and wound-related complications. Scheduling of surgery may present a unique opportunity to help smokers quit permanently. Primary care providers can play an important role in helping th...

journal_title：Mayo Clinic proceedings

authors： Warner DO

更新日期：2005-02-01 00:00:00

abstract：:Risk stratification and risk-benefit ratios are extremely important in guiding patient-physician interactions as well as patient and family counseling. Risks associated with percutaneous transluminal coronary angioplasty are (1) compromise of the vessel lumen or vessel integrity, (2) unsuccessful procedure, and (3) re...

journal_title：Mayo Clinic proceedings

authors： Holmes DR Jr

更新日期：2003-12-01 00:00:00

abstract：:A follow-up study of 224 male patients from Rochester, Minnesota, diagnosed with cryptorchidism during the period from 1935 through 1974 was conducted to assess the frequency of subsequent testicular neoplasms. Age-specific rates for testicular neoplasm in this community were used to estimate an expected number for co...

journal_title：Mayo Clinic proceedings

authors： Benson RC Jr,Beard CM,Kelalis PP,Kurland LT

更新日期：1991-04-01 00:00:00

abstract：:The frequently encountered disorder of venous thromboembolism (VTE) can cause serious morbidity and even death. Nevertheless, in more than 70% of patients who die of pulmonary embolism (PE), the diagnosis is not considered before death. Thus, clinicians should have a high index of suspicion for VTE, especially in high...

journal_title：Mayo Clinic proceedings

authors： Rosenow EC 3rd

更新日期：1995-01-01 00:00:00

abstract：:Epilepsy is one of the most common and challenging neurologic disorders affecting children. Although various modalities exist to treat pediatric-onset seizures, seizures in 25% of children who are diagnosed as having epilepsy remain refractory to available therapies. Of the 8 new antiepileptic drugs (AEDs) (felbamate,...

journal_title：Mayo Clinic proceedings

authors： Jarrar RG,Buchhalter JR

更新日期：2003-03-01 00:00:00

abstract：:Many diseases, mainly infectious and inhalational, have been associated with the use of hot tubs. "Hot tub lung" is a recently described disease entity associated with Mycobacterium avium complex (MAC) and is thought to be either an infection or a hypersensitivity pneumonitis. We describe 2 patients with progressively...

journal_title：Mayo Clinic proceedings

authors： Rickman OB,Ryu JH,Fidler ME,Kalra S

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To comparatively assess the natural history of patients of different ages undergoing transcatheter aortic valve replacement (TAVR). PATIENTS AND METHODS:For this study, we used the YOUNG TAVR, an international, multicenter registry investigating mortality trends up to 2 years in patients with aortic valve st...

journal_title：Mayo Clinic proceedings

authors： Navarese EP,Andreotti F,Kołodziejczak M,Wanha W,Lauten A,Veulemans V,Frediani L,Kubica J,de Cillis E,Wojakowski W,Ochala A,Zeus T,Bortone A,Buffon A,Jung C,Pestrichella V,Gurbel PA

更新日期：2019-08-01 00:00:00

abstract：:The use of pacemakers and implantable cardioverter-defibrillators continues to increase for the management of cardiac dysrhythmias and, more recently, heart failure. Long-term complications associated with their use include infection, lead failure, and spurious shocks. Although the risk of infection with intracardiac ...

journal_title：Mayo Clinic proceedings

authors： Cook RJ,Orszulak TA,Nkomo VT,Shuford JA,Edwards WD,Ryu JH

更新日期：2004-04-01 00:00:00

abstract：:Recent experience with 40 patients with the Zollinger-Ellison syndrome at all Mayo Clinic suggests that traditional clinical criteria for diagnosis are often absent or invalid. Patients are younger have a shorter duration of symptoms, and often present without prior gastric surgery. Clinical, roentgenographic, and end...

journal_title：Mayo Clinic proceedings

authors： Regan PT,Malagelada JR

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:To quantify the impact of the severe acute respiratory syndrome coronavirus 2 pandemic on emergency department volumes and patient presentations and evaluate changes in community mortality for the purpose of characterizing new patterns of emergency care use. PATIENTS AND METHODS:This is an observational cros...

journal_title：Mayo Clinic proceedings

authors： Walker LE,Heaton HA,Monroe RJ,Reichard RR,Kendall M,Mullan AF,Goyal DG

更新日期：2020-11-01 00:00:00

abstract：:By identifying structural chromosome anomalies, the clinical cytogenetics laboratory can play a critical role in the diagnosis and treatment of patients with birth defects. Although many new staining techniques have been developed throughout the years to aid in the detection of anomalous chromosomes, some abnormalitie...

journal_title：Mayo Clinic proceedings

authors： Kraker WJ,Borell TJ,Schad CR,Pennington MJ,Karnes PS,Dewald GW,Jenkins RB

更新日期：1992-07-01 00:00:00

abstract：:The aim of this study was to determine whether the characteristics of esophageal symptoms may be of diagnostic utility in distinguishing dysphagia of various causes. Included in the study were a total of 499 patients with three types of dysphagia: 234 with dysphagia related to an obstructive lesion in the esophagus, 1...

journal_title：Mayo Clinic proceedings

authors： Kim CH,Weaver AL,Hsu JJ,Rainwater L,Zinsmeister AR

更新日期：1993-10-01 00:00:00

abstract：:All women who enter menopause experience amenorrhea unless they receive hormone replacement therapy. In younger women, amenorrhea unrelated to pregnancy and lactation can be a distressing symptom. In addition to its psychologic morbidity, amenorrhea may be the manifesting feature of a wide array of anatomic and endocr...

journal_title：Mayo Clinic proceedings

authors： McIver B,Romanski SA,Nippoldt TB

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To assess the frequency and clinical implications of positive autoimmune serologies in patients with biopsy-confirmed idiopathic pulmonary fibrosis (IPF). PATIENTS AND METHODS:We reviewed the records of patients at our institution with biopsy-confirmed usual interstitial pneumonia (UIP) from January 1, 1995,...

journal_title：Mayo Clinic proceedings

authors： Moua T,Maldonado F,Decker PA,Daniels CE,Ryu JH

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To ascertain the usefulness of bone marrow and cerebrospinal fluid (CSF) examinations in identifying or predicting relapse in children with acute lymphoblastic leukemia (ALL) before discontinuation of chemotherapy. MATERIAL AND METHODS:We retrospectively reviewed the medical records of 113 children with ALL ...

journal_title：Mayo Clinic proceedings

authors： Hutt PJ,Sabio H,Gilchrist GS,O'Brien C

更新日期：1996-09-01 00:00:00

abstract：:Dyspnea is a common symptom that is difficult to define and can result from a wide variety of causes. This complex sensation that arises from multiple stimuli involves both subjective perceptions and objective reactions. In the assessment of patients with dyspnea, use of a systematic approach to determine the precipit...

journal_title：Mayo Clinic proceedings

authors： Gillespie DJ,Staats BA

更新日期：1994-07-01 00:00:00

abstract：:The updated cervical cancer screening guidelines recommend that women at average risk who have negative screening results undergo cervical cytological testing every 3 to 5 years. These recommendations do not pertain to women at high risk for cervical cancer. This article reviews recommendations for cervical cancer scr...

journal_title：Mayo Clinic proceedings

authors： Vegunta S,Files JA,Wasson MN

更新日期：2017-08-01 00:00:00

abstract：:The evaluation of the patient with diarrhea can be complex and the treatment challenging. In this article, the definition of diarrhea and the pathophysiologic mechanisms that lead to diarrhea are reviewed. A simplified 5-step approach to the patient with diarrhea is provided and applied in a case-oriented manner appli...

journal_title：Mayo Clinic proceedings

authors： Sweetser S

更新日期：2012-06-01 00:00:00

abstract：:Data from animal experiments and human studies implicate added sugars (eg, sucrose and high-fructose corn syrup) in the development of diabetes mellitus and related metabolic derangements that raise cardiovascular (CV) risk. Added fructose in particular (eg, as a constituent of added sucrose or as the main component o...

journal_title：Mayo Clinic proceedings

authors： DiNicolantonio JJ,O'Keefe JH,Lucan SC

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To assess overall perioperative and anesthetic care-specific patient satisfaction. DESIGN:We mailed questionnaires postoperatively to three groups of surgical patients (those who underwent anesthesia without complications, those who experienced airway management difficulties, and those who had cardiovascular...

journal_title：Mayo Clinic proceedings

authors： Brown DL,Warner ME,Schroeder DR,Offord KP

更新日期：1997-01-01 00:00:00

abstract：:A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise, may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords exercise and cognition) and manuscript bibliographies to examine the published evidence of a cognitive neuroprotective effect of exercise. M...

journal_title：Mayo Clinic proceedings

authors： Ahlskog JE,Geda YE,Graff-Radford NR,Petersen RC

更新日期：2011-09-01 00:00:00

abstract：:Breast cancer is the most common noncutaneous malignancy among every major ethnic group of women in the United States. Anthracyclines and taxanes are the most active and widely used chemotherapeutic agents for breast cancer, but the increased use of these agents at an early stage of disease often renders tumors resist...

journal_title：Mayo Clinic proceedings

authors： Moreno-Aspitia A,Perez EA

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To Investigate the frequency of valvular heart disease in patients taking pergolide. PATIENTS AND METHODS:The medical records of patients seen at the Mayo Clinic in Jacksonville, Fla, between 1998 and 2003 were searched electronically for the word pergolide and the presence of a 2-dimensional echocardiogram....

journal_title：Mayo Clinic proceedings

authors： Waller EA,Kaplan J,Heckman MG

更新日期：2005-08-01 00:00:00