Abstract:
:The ventriculoatrial shunt (VAS) was developed to control hydrocephalic syndromes effectively. Several complications, however, have been described after the procedure. One of the most serious consequences is the development of severe pulmonary hypertension attributed to multiple and recurrent pulmonary embolization caused by the catheter of the VAS; however, the frequency is exceedingly low. Herein we describe the experience with three patients in whom severe pulmonary hypertension developed after a VAS procedure. In two patients, refractory heart failure developed, an outcome that caused death within a brief period. The third patient underwent atrial thrombectomy and then pulmonary thromboendarterectomy; recovery was complete. Scientific evidence shows that initial embolization predisposes pulmonary vessels to develop further in situ thrombosis; thus, the vascular lung disease progresses despite removal of the embolic source. A review of the literature revealed that in patients with a VAS, pulmonary embolism and pulmonary hypertension were clinically diagnosed in only 0.4% and 0.3% of the cases, respectively, whereas postmortem diagnoses of pulmonary embolism and pulmonary hypertension were established in 59.7% and 6.3%, respectively. These discrepancies point out the difficulty of establishing the diagnosis of these serious pulmonary vascular complications while the patient is alive.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Pascual JM,Prakash UBdoi
10.1016/s0025-6196(12)60069-xsubject
Has Abstractpub_date
1993-12-01 00:00:00pages
1177-82issue
12eissn
0025-6196issn
1942-5546pii
S0025-6196(12)60069-Xjournal_volume
68pub_type
杂志文章abstract:OBJECTIVE:To assess the efficacy and tolerability of weekly oral cyclophosphamide in combination with alternate-day prednisone (CP) as salvage therapy for patients with relapsed multiple myeloma (MM) after autologous stem cell transplantation (ASCT). PATIENTS AND METHODS:We retrospectively reviewed the medical records...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.4065/80.12.1578
更新日期:2005-12-01 00:00:00
abstract::In Olmsted County, Minnesota, population-based epidemiologic research studies are possible because of a unique medical records linkage system, the Rochester Epidemiology Project (REP), which has been in place for almost half a century. We present a summary of epidemiologic data describing the incidence of skin disease...
journal_title:Mayo Clinic proceedings
pub_type: 杂志文章,评审
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更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy of laparoscopy in the diagnosis of intra-abdominal lymphoma. PATIENTS AND METHODS:The medical records of patients with suspected primary or recurrent lymphoma who underwent laparoscopy between March 1991 and March 2003 were reviewed. Demographic, clinical, operative, and pathologic dat...
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.mayocp.2018.01.024
更新日期:2018-05-01 00:00:00
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:10.1016/s0025-6196(12)61764-9
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journal_title:Mayo Clinic proceedings
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pub_type: 杂志文章
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journal_title:Mayo Clinic proceedings
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1980-08-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Mayo Clinic proceedings
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更新日期:2018-08-01 00:00:00
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
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更新日期:1987-01-01 00:00:00
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journal_title:Mayo Clinic proceedings
pub_type: 杂志文章
doi:
更新日期:1976-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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更新日期:2019-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00