Different effects of melatonin on experimental granulomatous inflammation.

abstract：:Colchicine and methotrexate are commonly used in the treatment of gout and rheumatoid arthritis, respectively; however the mechanism(s) of action of these drugs remain(s) unknown. The objective of this study was to determine whether colchicine and methotrexate can modify the adhesion and emigration of leukocytes in po...

journal_title：Inflammation

authors： Asako H,Kubes P,Baethge BA,Wolf RE,Granger DN

更新日期：1992-02-01 00:00:00

abstract：:Macrophages are one of the most heterogenic immune cells involved in skeletal muscle regeneration. After skeletal muscle damage, M1 phenotypes exhibit pro-inflammatory reaction. In a later stage, they are converted to M2 phenotypes with anti-inflammatory properties. To study when gene expressions of macrophage polariz...

journal_title：Inflammation

authors： Minari AL,Oyama LM,Dos Santos RV

更新日期：2015-02-01 00:00:00

abstract：:Exacerbations in chronic obstructive pulmonary disease (COPD) reduce quality of life and are associated with a more rapid deterioration of the disease. Growth differentiation factor-15 (GDF-15) is a novel candidate exacerbation biomarker. In this study, we aimed to assess GDF-15 as a biomarker of acute exacerbation of...

journal_title：Inflammation

authors： Mutlu LC,Altintas N,Aydin M,Tulubas F,Oran M,Kucukyalin V,Kaplan G,Gurel A

更新日期：2015-10-01 00:00:00

abstract：:Postoperative ileus is a common complication after intra-abdominal surgery. Nitric oxide produced by macrophages in the inflamed gastrointestinal tract plays a crucial role in the pathogeny of postoperative ileus. Honokiol, extracted from the bark of Magnolia spp., is a natural compound with a biphenolic structure. In...

journal_title：Inflammation

authors： Mihara T,Mikawa S,Kaji N,Endo M,Oikawa T,Tong-Rong J,Ozaki H,Hori M

更新日期：2017-08-01 00:00:00

abstract：:The ability of peripheral blood neutrophils to injure elements of the alveolar septum was assessed. Experiments consisted of activating previously isolated neutrophils (PMNs) with a soluble (phorbol myristate acetate, PMA) and a particulate (zymosan) trigger, and measuring detachment of 51Cr-labeled epithelial cells. ...

journal_title：Inflammation

authors： Brown DM,Brown GM,Macnee W,Donaldson K

更新日期：1992-02-01 00:00:00

abstract：:The world's number one cause of death is cardiovascular diseases. The pathogenesis of different disease entities in the cardiovascular disease spectrum is complicated and multifactorial. Inflammation in these complicated etiologies serves as a key position and is a significant cause of atherosclerosis, which contribut...

journal_title：Inflammation

authors： Liaqat A,Asad M,Shoukat F,Khan AU

更新日期：2020-12-01 00:00:00

abstract：:CD4+ T cell subset imbalance plays an important role in the development of diabetic complications. Neutrophils have recently been known as the regulator of CD4+ T cell differentiation. However, whether neutrophils affect CD4+ T cell population in diabetes is still elusive. In this study, we investigated the effect of ...

journal_title：Inflammation

authors： Lu H,Xu S,Liang X,Dai Y,Huang Z,Ren Y,Lin J,Liu X

更新日期：2019-04-01 00:00:00

abstract：:Intervertebral disc degeneration (IVDD) is considered to be the fundamental cause of the occurrence and development of lumbar disc herniation (LDH). The degeneration of IVDD is mainly caused by the participation of inflammatory factors. Thus, it is of great significance to analyze the pathogenesis of IVDD, which may g...

journal_title：Inflammation

authors： Lin X,Lin Q

更新日期：2020-10-01 00:00:00

abstract：:We compared exhaled breath condensate (EBC) and induced sputum (IS) for assessing inflammation in pulmonary diseases in patients with obstructive lung disease (n = 20), persistent cough >6 months (n = 20), interstitial lung disease (n = 25) and controls (n = 10). EBC was collected by suspending a Teflon perfluoroalkox...

journal_title：Inflammation

authors： Fireman E,Shtark M,Priel IE,Shiner R,Mor R,Kivity S,Fireman Z

更新日期：2007-04-01 00:00:00

abstract：:To elucidate the role of major chemotactic factors, cytokine-induced neutrophil chemoattractant (CINC), leukotriene B4 (LTB4) and C5a in lipopolysaccharide (LPS)-induced acute lung injury in rat, we employed three reagents: anti-CINC-1 antibody, an LTB4 receptor antagonist (ONO-4057) and an anti-complementary agent (K...

journal_title：Inflammation

authors： Yamasawa H,Ishii Y,Kitamura S

更新日期：1999-06-01 00:00:00

abstract：:The purpose of the present study is to evaluate the effect of emu oil on bioavailability of curcumin when co-administered and to evaluate the property that enhances the anti-inflammatory potential of curcumin. Oral bioavailability of curcumin in combination with emu oil was determined by measuring the plasma concentra...

journal_title：Inflammation

authors： Jeengar MK,Shrivastava S,Nair K,Singareddy SR,Putcha UK,Talluri MV,Naidu VG,Sistla R

更新日期：2014-12-01 00:00:00

abstract：:Exposure to ultraviolet (UV) light impairs the function of inflammatory cells. Urocanic acid (UCA) in an stratum corneum has been suggested as a mediator in the immunosuppression of lymphoid cells detected after irradiation with UVB (UV wavelengths 280-320 nm). In this study, we examined the effects of the two UCA iso...

journal_title：Inflammation

authors： Kivistö K,Punnonen K,Toppari J,Leino L

更新日期：1996-10-01 00:00:00

abstract：:Previous studies indicate that aspirin can promote neutrophil (PMN) adhesion to endothelial cells and neutrophil-mediated endothelial cell detachment. The objectives of the present study were to determine whether PMN adhesion is a prerequisite for aspirin-induced, PMN-mediated endothelial cell detachment and whether n...

journal_title：Inflammation

authors： Yoshida N,Cepinskas G,Granger DN,Anderson DC,Wolf RE,Kvietys PR

更新日期：1995-06-01 00:00:00

abstract：:We aimed to compare serum levels of the inflammatory mediators including C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and asymmetric dimethylarginine (ADMA) in chronic obstructive pulmonary disease (COPD), obstructive sleep apnea syndrome (OSAS), and their coexistence called overlap syndrome (OVS). In ad...

journal_title：Inflammation

authors： Nural S,Günay E,Halici B,Celik S,Ünlü M

更新日期：2013-02-01 00:00:00

abstract：:Macrophage polarization is a dynamic and integral process of tissue inflammation and remodeling. Here we demonstrate an important role of Aurora kinase A in the regulation of inflammatory M1 macrophage polarization. We found that there was an elevated expression of Aurora-A in M1 macrophages and inhibition of Aurora-A...

journal_title：Inflammation

authors： Ding L,Gu H,Gao X,Xiong S,Zheng B

更新日期：2015-04-01 00:00:00

abstract：:Human neutrophils (PMNs) which have been incubated with lipoteichoic acid (LTA) from group A streptococci generated large amounts of superoxide (O2- chemiluminescence and hydrogen peroxide when challenged with anti-LTA antibodies. Cytochalasin B further enhanced O2- generation. The onset of O2- generation by the LTA-a...

journal_title：Inflammation

authors： Ginsburg I,Fligiel SE,Ward PA,Varani J

更新日期：1988-12-01 00:00:00

abstract：:It has been well established that diet high in cholesterol and saturated fatty acids could significantly elevate plasma cholesterol levels and also increase the risk of cardiovascular diseases. We hypothesize that repeated systemic Escherichia coli (E. coli) in conjunction with hypercholesterolemia, leads to developme...

journal_title：Inflammation

authors： Dutta K,Nandi D,Bishayi B

更新日期：2009-04-01 00:00:00

abstract：:In the present study the content of substance P (SP)-, neurokinin A (NKA)-, calcitonin gene-related peptide (CGRP)- and neuropeptide Y (NPY)-like immunoreactivity (-LI) was measured in rats cerebrospinal fluid (CSF), plasma and perfusates (PF) from both elbow enthesis during acute inflammation. Either substance P, SP,...

journal_title：Inflammation

authors： Haker E,Theodorsson E,Lundeberg T

更新日期：1997-02-01 00:00:00

abstract：:Nicotine has anti- and pro-inflammatory properties in various cells. Its role in aortic vascular smooth muscle cells (VSMC) was explored. Human aortic VSMC were cultured. After nicotine (1.0 μM) and/or pyrrolidinedithiocarbamic acid (PDTC, 50 μM) treatment, the activation of nuclear factor κB (NFκB) was investigated. ...

journal_title：Inflammation

authors： Wang Y,Zhang F,Yang W,Xue S

更新日期：2012-02-01 00:00:00

abstract：:This study investigates the mode of action of Neophytadiene (MT), a molecule isolated from a marine algae Turbinaria ornata in LPS-induced inflammation in both in vitro and in vivo conditions. Neophytadiene (25, 50, 100 μM/mL) was treated to LPS-stimulated RAW 264.7 macrophages cells to identify its anti-inflammatory ...

journal_title：Inflammation

authors： Bhardwaj M,Sali VK,Mani S,Vasanthi HR

更新日期：2020-06-01 00:00:00

abstract：:The present study evaluated the anti-inflammatory effect of nanoencapsulated curcuminoid preparations of poly(vinyl pyrrolidone) (Nano-cur) and free curcuminoids (Cur) in an experimental model of croton oil-induced cutaneous inflammation. Male Swiss mice, weighing 25-30 g, received oral treatment by gavage 1 h before ...

journal_title：Inflammation

authors： Lima EP,Gonçalves OH,Ames FQ,Castro-Hoshino LV,Leimann FV,Cuman RKN,Comar JF,Bersani-Amado CA

更新日期：2020-11-09 00:00:00

abstract：:The aim of this study is to investigate the effects of molecular hydrogen (H2) and suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, on paraquat (PQ)-stimulated production of reactive oxygen species (ROS) and tumor necrosis factor alpha (TNF-α) in macrophages. First, the PQ optimal concentration...

journal_title：Inflammation

authors： Li J,Wu X,Chen Y,Zeng R,Zhao Y,Chang P,Wang D,Zhao Q,Deng Y,Li Y,Alam HB,Chong W

更新日期：2016-12-01 00:00:00

abstract：:Both recombinant IL-1 alpha and -beta caused an upregulation of C3b receptors (CR1) on human neutrophils and caused a receptor-mediated enhancement of phagocytosis of C3b.IgG-coated microspheres by these leukocytes. The alpha and beta forms of the recombinant cytokine were of comparable potency regarding CR1 upregulat...

journal_title：Inflammation

authors： Ogle JD,Noel JG,Balasurbramaniam A,Sramkoski RM,Ogle CK,Alexander JW

更新日期：1990-04-01 00:00:00

abstract：:Diabetic retinopathy shares some similarity with chronic inflammation and Müller cells dysfunction may play an important role in its initiation and progression since these cells are thought to be a major source of inflammatory factors. The goal of this study was to examine the effect of cytokines on human retinal Müll...

journal_title：Inflammation

authors： Liu X,Ye F,Xiong H,Hu D,Limb GA,Xie T,Peng L,Yang W,Sun Y,Zhou M,Song E,Zhang DY

更新日期：2014-10-01 00:00:00

abstract：:To determine the effect of heat stress on histopathology of acute lung injury (ALI) caused by administration of lipopolysaccharide (LPS), and to determine the roles of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, interferon (IFN)-gamma, IL-10 and surfactants in heat-induced tolerance to ALI, we administe...

journal_title：Inflammation

authors： Koh Y,Lee YM,Lim CM,Lee SS,Shim TS,Lee SD,Kim WS,Kim DS,Kim WD

更新日期：2001-06-01 00:00:00

abstract：:The possibility of inflammation and neutrophil activation in response to indoor air pollution (IAP) from biomass fuel use has been investigated. For this, 142 premenopausal, never-smoking women (median age, 34 years) who cook exclusively with biomass (wood, dung, crop wastes) and 126 age-matched control women who cook...

journal_title：Inflammation

authors： Banerjee A,Mondal NK,Das D,Ray MR

更新日期：2012-04-01 00:00:00

abstract：:Isoliquiritigenin (ILG), a major ingredient of licorice, has been reported to have anti-oxidative and anti-inflammatory effects. The aim of this study was to investigate the protective effects of ILG on lung injury using an animal model of lipopolysaccharide (LPS)-induced acute lung injury (ALI). Male BALB/c mice were...

journal_title：Inflammation

authors： Zhang W,Wang G,Zhou S

更新日期：2018-08-01 00:00:00

abstract：:Human neutrophils were demonstrated to possess interleukin-2 receptor (IL-2R) beta and gamma chains, not alpha chain and the binding of IL-2 to the IL-2R beta chain on neutrophils plays an important regulatory role in neutrophil functions. We have investigated in this study the hypothesis that recombinant human IL-2 (...

journal_title：Inflammation

authors： Li J,Gyorffy S,Lee S,Kwok CS

更新日期：1996-08-01 00:00:00

abstract：:Current knowledge implicates pleural mesothelial cells as mainly responsible for inflammatory responses in the pleural space. However, a vast body of recent evidence underscores the important role of fibroblasts in the process of inflammation in several types of tissues. We hypothesize that HPFBs (human pleural fibrob...

journal_title：Inflammation

authors： Loghmani F,Mohammed KA,Nasreen N,Van Horn RD,Hardwick JA,Sanders KL,Antony VB

更新日期：2002-04-01 00:00:00

abstract：:Herein, we reported our experience in colchicine-resistant familial Mediterranean fever (FMF) patients who are treated with anti-interleukin-1 (IL-1) drugs. A retrospective review of medical records of anti-IL-1 recipients was performed. The main clinical characteristics of these patients and the evolution after anti-...

journal_title：Inflammation

authors： Cetin P,Sari I,Sozeri B,Cam O,Birlik M,Akkoc N,Onen F,Akar S

更新日期：2015-02-01 00:00:00