Improvement of bioavailability and anti-inflammatory potential of curcumin in combination with emu oil.

abstract：:T cells adhere to human dermal fibroblasts (HDF). This cellular interaction leads to a pronounced secretion of the proinflammatory cytokines IL-6 and IL-8 via a juxtacrine stimulation induced by HDF-associated IL-1. Upon stimulation, fibroblasts express various surface proteins such as MCH-I molecules, which may inter...

journal_title：Inflammation

authors： Spörri B,Bickel M,Limat A,Waelti ER,Hunziker T,Wiesmann UN

更新日期：1997-08-01 00:00:00

abstract：:The respiratory burst is a series of metabolic events which result in the production of microbicidal oxidants by phagocytes. The enzyme responsible for the respiratory burst is a membrane-bound oxidase which catalyzes the production of O-2 by the NADPH-dependent reduction of oxygen. Activity of this oxidase is diminis...

journal_title：Inflammation

authors： Kaufman MR,Babior BM

更新日期：1983-09-01 00:00:00

abstract：:Icariin is a flavonoid isolated from the traditional Chinese herbal medicine Epimedium brevicornum Maxim and has been reported to be effective for the treatment of a variety of cardiovascular diseases. The aim of the present study was to investigate the effect and mechanism of icariin on atherosclerosis (AS) using a h...

journal_title：Inflammation

authors： Hu Y,Sun B,Liu K,Yan M,Zhang Y,Miao C,Ren L

更新日期：2016-02-01 00:00:00

abstract：:Baicalein shows anti-inflammatory effects in human rheumatoid arthritis fibroblast-like synoviocytes (RAFLS). Considering its anti-proliferatory effects on various cancer cells, we investigated the effects of baicalein on interleukin-1 beta (IL-1β)-induced proliferation of human RAFLS. Cell proliferation was examined ...

journal_title：Inflammation

authors： Chen S,Yang Y,Feng H,Wang H,Zhao R,Liu H

更新日期：2014-02-01 00:00:00

abstract：:Lipids from the sputum of patients with asthma and with cystic fibrosis were isolated and characterized. In both cases, lipids constituted approximately 30% of the dry material. Phosphatidlycholine was the most abundant lipid, Significant amounts of phosphatidylethanolamine and phosphatidylglycerol were present. Hexos...

journal_title：Inflammation

authors： Sahu S,Lynn WS

更新日期：1978-03-01 00:00:00

abstract：:The present study aimed at characterizing the phenotype and functions of adherent synovial fluid (SF) cells derived from rheumatoid arthritis (RA), comparing with fibroblast-like synoviocytes (FLS) derived from RA synovial tissue (ST). Adherent SF-derived cells were spindle-shaped from passages 1-6 under light microsc...

journal_title：Inflammation

authors： Ahn JK,Kim H,Lee J,Bae EK,Cha HS,Koh EM

更新日期：2008-12-01 00:00:00

abstract：:The widely used mouse air pouch model of acute inflammation is inducible in a variety of inbred strains, but the potential influence of genetic background and gender on inflammation severity has never been examined. We directly compared the degree of inflammation induced in the air pouch model across four commonly uti...

journal_title：Inflammation

authors： Delano DL,Montesinos MC,D'Eustachio P,Wiltshire T,Cronstein BN

更新日期：2005-02-01 00:00:00

abstract：:Postoperative ileus is a common complication after intra-abdominal surgery. Nitric oxide produced by macrophages in the inflamed gastrointestinal tract plays a crucial role in the pathogeny of postoperative ileus. Honokiol, extracted from the bark of Magnolia spp., is a natural compound with a biphenolic structure. In...

journal_title：Inflammation

authors： Mihara T,Mikawa S,Kaji N,Endo M,Oikawa T,Tong-Rong J,Ozaki H,Hori M

更新日期：2017-08-01 00:00:00

abstract：:It has been well established that diet high in cholesterol and saturated fatty acids could significantly elevate plasma cholesterol levels and also increase the risk of cardiovascular diseases. We hypothesize that repeated systemic Escherichia coli (E. coli) in conjunction with hypercholesterolemia, leads to developme...

journal_title：Inflammation

authors： Dutta K,Nandi D,Bishayi B

更新日期：2009-04-01 00:00:00

abstract：:Immune dysfunction contributes to secondary infection and worse outcomes in sepsis. Regulatory T cells (Tregs) have been implicated in sepsis-induced immunosuppression. Nevertheless, the role of Tregs in secondary infection after sepsis remains to be determined. In the present study, a two-hit model which mimics clini...

journal_title：Inflammation

authors： Hu ZQ,Yao YM,Chen W,Bian JL,Zhao LJ,Chen LW,Hong GL,Lu ZQ,Zhao GJ

更新日期：2018-10-01 00:00:00

abstract：:Slow translocation of protein kinase C was observed by both auranofin and gold sodium thiomalate pretreatment of neutrophils. Both gold compounds failed to influence the activity of this enzyme directly when cell-free studies were performed. In intact neutrophils incubated with 5.1-20.3 microM auranofin, protein kinas...

journal_title：Inflammation

authors： Parente JE,Davis P,Wong K

更新日期：1987-09-01 00:00:00

abstract：:Karyopherin-α2 (KPNA2) functions as an adaptor that transports several proteins to the nucleus. We investigated the function and possible mechanisms of KPNA2 involved in rheumatoid arthritis (RA). Western blotting and immunohistochemistry showed the protein expression of KPNA2 increased in synovial tissue of RA patien...

journal_title：Inflammation

authors： Liu Z,Zhang D,Sun C,Tao R,Xu X,Xu L,Cheng H,Xiao M,Wang Y

更新日期：2015-12-01 00:00:00

abstract：:This study aimed to investigate molecule B7-H3 expression profiles of patients with ankylosing spondylitis (AS) and the clinical significance of B7-H3 in the pathogenesis of AS. Serum B7-H3 levels were measured by ELISA in patients with AS and healthy controls. The expression of B7-H3 protein and mRNA on CD14+ monocyt...

journal_title：Inflammation

authors： Yan R,Hu Y,Yu P,Wen H,Feng P,Yang S

更新日期：2015-01-01 00:00:00

abstract：:To elucidate the role of major chemotactic factors, cytokine-induced neutrophil chemoattractant (CINC), leukotriene B4 (LTB4) and C5a in lipopolysaccharide (LPS)-induced acute lung injury in rat, we employed three reagents: anti-CINC-1 antibody, an LTB4 receptor antagonist (ONO-4057) and an anti-complementary agent (K...

journal_title：Inflammation

authors： Yamasawa H,Ishii Y,Kitamura S

更新日期：1999-06-01 00:00:00

abstract：:Rheumatoid synovial fluids generated significantly greater amounts of superoxide, lysosomal enzymes, and superoxide dismutase from neutrophils into extracellular fluid than osteoarthritic synovial fluids. Rheumatoid factors isolated from serum suppressed superoxide-generating activity of performed immune complexes, bu...

journal_title：Inflammation

authors： Shingu M,Todoroki T,Nobunaga M

更新日期：1987-06-01 00:00:00

abstract：:Tumour necrosis factor-α (TNFα) and polymorphonuclear neutrophils play key and interrelated roles in the inflammatory response against infectious agents. However, these entities can mediate significant tissue damage if their biological activity becomes deregulated. We have previously shown that canine hyperimmune froz...

journal_title：Inflammation

authors： Essien BE,Kotiw M

更新日期：2012-02-01 00:00:00

abstract：:Neurodegenerative diseases such as Alzheimer, Parkinson, amyotrophic lateral sclerosis, and Huntington are incurable and debilitating conditions that result in progressive death of the neurons. The definite diagnosis of a neurodegenerative disorder is disadvantaged by the difficulty in obtaining biopsies and thereby t...

journal_title：Inflammation

authors： Nuzzo D,Picone P,Caruana L,Vasto S,Barera A,Caruso C,Di Carlo M

更新日期：2014-06-01 00:00:00

abstract：:A rat sponge implant model was used to examine the role of protein kinase C (PKC) in angiogenesis. Neovascular response was determined by measurements of relative sponge blood flow by a 133Xe clearance technique and confirmed histologically. Morphometric analysis was used to quantitate the amount of fibrovascular grow...

journal_title：Inflammation

authors： Hu DE,Fan TP

更新日期：1995-02-01 00:00:00

abstract：:Comparison of the physiologic responses in rabbits to the intravenous infusion of two polymorphonuclear neutrophil (PMN) activators, N-formyl-methionyl-leucyl-phenylalanine (FMLP) and phorbol myristate acetate (PMA), has revealed marked differences in kinetics for activation between these agents. FMLP infusion was ass...

journal_title：Inflammation

authors： Lafuze JE,Baker MD,Oakes AL,Baehner RL

更新日期：1987-12-01 00:00:00

abstract：:The levels of mRNA for plasma proteins and for metallothionein in rat liver during the acute-phase response were studied by hybridization to specific cDNA probes. The mRNA for alpha 2-macroglobulin, the beta-chain of fibrinogen, alpha 1-acid glycoprotein (so-called acute-phase reactants) reached a maximum level betwee...

journal_title：Inflammation

authors： Schreiber G,Aldred AR,Thomas T,Birch HE,Dickson PW,Tu GF,Heinrich PC,Northemann W,Howlett GJ,de Jong FA

更新日期：1986-03-01 00:00:00

abstract：:Our study showed that S-methylisothiourea (SMT) had anti-inflammatory effects in treating herpes simplex encephalitis in mice, and SMT also induced apoptosis of herpes simplex virus (HSV-1)-infected microglial cells. Both animal and cell models were employed in this study. Both models included the following five group...

journal_title：Inflammation

authors： Guo YJ,Li W,Li XF,Zhao L,Zhang SL,Zhou Y,Dong JH,Mei YW

更新日期：2011-10-01 00:00:00

abstract：:Endoplasmic reticulum stress (ERS) plays an important role in cerebral ischemia-reperfusion injury (CIRI) by regulating apoptosis. Although the role of long non-coding RNA (LncRNA) KCNQ1OT1 in CIRI has been reported, the specific mechanism is still unclear. In this paper, the regulation of ERS by LncRNA KCNQ1OT1 in CI...

journal_title：Inflammation

authors： Li Y,Yi M,Wang D,Zhang Q,Yang L,Yang C

更新日期：2020-12-01 00:00:00

abstract：:Migration inhibitory factor (MIF) is associated with multiple organ dysfunction syndrome (MODS) in patients with systemic inflammatory response syndrome (SIRS). Our purposes were to determine the serum MIF, cortisol, and tumor narcosis factor-α (TNF-α) and to investigate the influences of the balance between the level...

journal_title：Inflammation

authors： Hayakawa M,Katabami K,Wada T,Minami Y,Sugano M,Shimojima H,Kubota N,Uegaki S,Sawamura A,Gando S

更新日期：2011-06-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is the predominant cause of irreversible blindness in the elderly population. Despite intensive basic and clinical research, its pathogenesis remains unclear. However, evidence suggests that immunological and inflammatory factors contribute to the pathogenesis of AMD. A newly ide...

journal_title：Inflammation

authors： Liu XC,Liu XF,Jian CX,Li CJ,He SZ

更新日期：2012-04-01 00:00:00

abstract：:Alveolar macrophages (AMs) can initiate lung inflammation by producing pro-inflammatory cytokines and chemokines, but they participate actively in the prevention of inflammation during acute lung injury (ALI). Heme oxygenase-1 (HO-1) is mainly expressed in AMs and has anti-inflammatory properties in ALI, but the anti-...

journal_title：Inflammation

authors： Hualin C,Wenli X,Dapeng L,Xijing L,Xiuhua P,Qingfeng P

更新日期：2012-06-01 00:00:00

abstract：:Inflammatory cells, macrophages induced by lipopolysaccharide (LPS) stimulation, lead to the production of inflammatory cytokines, which are crucial to host defense. MicroRNAs are short noncoding RNAs that regulate key biological processes via suppression of gene expression at posttranscriptional levels. Recently, miR...

journal_title：Inflammation

authors： He Y,Sun X,Huang C,Long XR,Lin X,Zhang L,Lv XW,Li J

更新日期：2014-02-01 00:00:00

abstract：:1,8-Cineol is a major monoterpene principally from eucalyptus essential oils and has been shown to exert anti-inflammatory, antiviral, and inhibitory of nuclear factor (NF)-kB effect. In the present study, we evaluated the effect of 1,8-cineol on mice infected with influenza A virus. We found that 1,8-cineol protects ...

journal_title：Inflammation

authors： Li Y,Lai Y,Wang Y,Liu N,Zhang F,Xu P

更新日期：2016-08-01 00:00:00

abstract：:The purpose of this study was to evaluate the rabbit anterior eye chamber as a quantitative measure of leukotaxis using 51Cr-labeled homologous leukocytes and then to determine the effects of ibuprofen on N-formyl-methionyl-leucyl-phenylalanine (FMLP) -induced leukotaxis. Leukocyte accumulation was assessed at various...

journal_title：Inflammation

authors： Shimanuki T,Nakamura RM,Dizerega GS

更新日期：1985-09-01 00:00:00

abstract：:Induction of hypoxia for 2.5 h in perfused cat livers resulted in a 10-fold increase in cathepsin D and a 15-fold increase in lactic dehydrogenase (LDH) activities in the perfusate and a 42% depression of the clearance rate of particles by the reticuloendothelial system (RES). Addition of 10(-3) M methylprednisolone (...

journal_title：Inflammation

authors： Carlson RP,Lefer AM

更新日期：1976-12-01 00:00:00

abstract：:CD4+ T cell subset imbalance plays an important role in the development of diabetic complications. Neutrophils have recently been known as the regulator of CD4+ T cell differentiation. However, whether neutrophils affect CD4+ T cell population in diabetes is still elusive. In this study, we investigated the effect of ...

journal_title：Inflammation

authors： Lu H,Xu S,Liang X,Dai Y,Huang Z,Ren Y,Lin J,Liu X

更新日期：2019-04-01 00:00:00