Interpreting changes in measles genotype: the contribution of chance, migration and vaccine coverage.

Abstract:

BACKGROUND:In some populations, complete shifts in the genotype of the strain of measles circulating in the population have been observed, with given genotypes being replaced by new genotypes. Studies have postulated that such shifts may be attributable to differences between the fitness of the new and the old genotypes. METHODS:We developed a stochastic model of the transmission dynamics of measles, simulating the effects of different levels of migration, vaccination coverage and importation of new genotypes on patterns in the persistence and replacement of indigenous genotypes. RESULTS:The analyses illustrate that complete replacement in the genotype of the strain circulating in populations may occur because of chance. This occurred in >50% of model simulations, for levels of vaccination coverage and numbers of imported cases per year which are compatible with those observed in several Western European populations (>80% and >3 per million per year respectively) and for the given assumptions in the model. CONCLUSION:The interpretation of genotypic data, which are increasingly being collected in surveillance programmes, needs to take account of the underlying vaccination coverage and the level of the importation rate of measles cases into the population.

journal_name

BMC Infect Dis

journal_title

BMC infectious diseases

authors

Nojiri S,Vynnycky E,Gay N

doi

10.1186/1471-2334-8-44

subject

Has Abstract

pub_date

2008-04-11 00:00:00

pages

44

issn

1471-2334

pii

1471-2334-8-44

journal_volume

8

pub_type

杂志文章
  • Reproductive and genital health and risk of cervical human papillomavirus infection: results from the Ludwig-McGill cohort study.

    abstract:BACKGROUND:There are inconsistencies in the literature on reproductive and genital health determinants of human papillomavirus (HPV) infection, the primary cause of cervical cancer. We examined these factors in the Ludwig-McGill Cohort Study, a longitudinal, repeated-measurements investigation on the natural history of...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1446-x

    authors: Shaw E,Ramanakumar AV,El-Zein M,Silva FR,Galan L,Baggio ML,Villa LL,Franco EL,Ludwig-McGill Cohort Study.

    更新日期:2016-03-08 00:00:00

  • Infectious sacroiliitis: a retrospective, multicentre study of 39 adults.

    abstract:BACKGROUND:Non-brucellar and non-tuberculous infectious sacroiliitis (ISI) is a rare disease, with misleading clinical signs that delay diagnosis. Most observations are based on isolated case reports or small case series. Our aim was to describe the clinical, bacteriological, and radiological characteristics of ISI, as...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2334-12-305

    authors: Hermet M,Minichiello E,Flipo RM,Dubost JJ,Allanore Y,Ziza JM,Gaudin P,Thomas T,Dernis E,Glace B,Regnier A,Soubrier M

    更新日期:2012-11-15 00:00:00

  • Clinical outcomes of spontaneous bacterial peritonitis due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: a retrospective matched case-control study.

    abstract:BACKGROUND:Clinical outcomes of spontaneous bacterial peritonitis (SBP) due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species (ESBL-EK) have not been adequately investigated. METHODS:We conducted a retrospective matched case-control study to evaluate the outcomes of SBP due to ESBL-...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-9-41

    authors: Song KH,Jeon JH,Park WB,Park SW,Kim HB,Oh MD,Lee HS,Kim NJ,Choe KW

    更新日期:2009-04-12 00:00:00

  • Tuberculosis mortality and associated factors at King Abdulaziz Medical City Hospital.

    abstract:BACKGROUND:Tuberculosis (TB) continues to be a public health challenge in Saudi Arabia, particularly for the elderly. This study was conducted to estimate mortality per 1000 person-year among TB and resistant TB cases and to identifying factors associated with mortality. METHODS:This is a retrospective cohort study of...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4063-7

    authors: Aljadani R,Ahmed AE,Al-Jahdali H

    更新日期:2019-05-16 00:00:00

  • Colonization of toxigenic Clostridium difficile among ICU patients: a prospective study.

    abstract:BACKGROUND:A prospective study was performed to investigate the prevalence of colonization among ICU patients and to examine whether asymptomatic carriers were the source of subsequent C. difficile infection (CDI) and acquisition of toxigenic C. difficile. METHODS:Rectal swabs were collected from adult patients on adm...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1729-2

    authors: Zhang X,Wang X,Yang J,Liu X,Cai L,Zong Z

    更新日期:2016-08-09 00:00:00

  • Evaluating clinical effectiveness of 13-valent pneumococcal conjugate vaccination against pneumonia among middle-aged and older adults in Catalonia: results from the EPIVAC cohort study.

    abstract:BACKGROUND:Benefits using the 13-valent pneumococcal conjugate vaccine (PCV13) in adults are controversial. This study investigated clinical effectiveness of PCV13 vaccination in preventing hospitalisation from pneumonia among middle-aged and older adults. METHODS:Population-based cohort study involving 2,025,730 indi...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3096-7

    authors: Vila-Corcoles A,Ochoa-Gondar O,de Diego C,Satue E,Aragón M,Vila-Rovira A,Gomez-Bertomeu F,Magarolas R,Figuerola-Massana E,Raga X,Perez MO,Ballester F

    更新日期:2018-04-27 00:00:00

  • Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal.

    abstract:BACKGROUND:Acute inflammatory reactions are a frequently occurring, tissue destructing phenomenon in infectious- as well as autoimmune diseases, providing clinical challenges for early diagnosis. In leprosy, an infectious disease initiated by Mycobacterium leprae (M. leprae), these reactions represent the major cause o...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12879-015-1128-0

    authors: Khadge S,Banu S,Bobosha K,van der Ploeg-van Schip JJ,Goulart IM,Thapa P,Kunwar CB,van Meijgaarden KE,van den Eeden SJ,Wilson L,Kabir S,Dey H,Goulart LR,Lobato J,Carvalho W,Bekele Y,Franken KL,Aseffa A,Spencer JS,Osk

    更新日期:2015-10-28 00:00:00

  • Joint Bayesian modeling of time to malaria and mosquito abundance in Ethiopia.

    abstract:BACKGROUND:This paper studies the effect of mosquito abundance and malaria incidence in the last 3 weeks, and their interaction, on the hazard of time to malaria in a previously studied cohort of children in Ethiopia. METHODS:We model the mosquito abundance and time to malaria data jointly in a Bayesian framework. RE...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2496-4

    authors: Belay DB,Kifle YG,Goshu AT,Gran JM,Yewhalaw D,Duchateau L,Frigessi A

    更新日期:2017-06-12 00:00:00

  • Evaluation of alternative respiratory syndromes for specific syndromic surveillance of influenza and respiratory syncytial virus: a time series analysis.

    abstract:BACKGROUND:Syndromic surveillance is increasingly being evaluated for its potential for early warning of increased disease activity in the population. However, interpretation is hampered by the difficulty of attributing a causative pathogen. We described the temporal relationship between laboratory counts of influenza ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-9-190

    authors: Schindeler SK,Muscatello DJ,Ferson MJ,Rogers KD,Grant P,Churches T

    更新日期:2009-11-29 00:00:00

  • Genetic diversity of Leishmania donovani that causes cutaneous leishmaniasis in Sri Lanka: a cross sectional study with regional comparisons.

    abstract:BACKGROUND:Leishmania donovani is the etiological agent of visceral leishmaniasis (VL) in the Indian subcontinent. However, it is also known to cause cutaneous leishmaniasis (CL) in Sri Lanka. Sri Lankan L. donovani differs from other L. donovani strains, both at the molecular and biochemical level. To investigate the ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2883-x

    authors: Kariyawasam UL,Selvapandiyan A,Rai K,Wani TH,Ahuja K,Beg MA,Premathilake HU,Bhattarai NR,Siriwardena YD,Zhong D,Zhou G,Rijal S,Nakhasi H,Karunaweera ND

    更新日期:2017-12-22 00:00:00

  • Prolonged polyarthralgia in a German traveller with Mayaro virus infection without inflammatory correlates.

    abstract:BACKGROUND:Mayaro virus is endemic in South America and sporadic outbreaks have been described. It causes a dengue-like febrile illness accompanied by severe and long-lasting polyarthralgias. Outside endemic regions, however, the disease is not well known and can be misdiagnosed as dengue. International travellers are ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-369

    authors: Theilacker C,Held J,Allering L,Emmerich P,Schmidt-Chanasit J,Kern WV,Panning M

    更新日期:2013-08-08 00:00:00

  • Investigation of a cross-border case of Lassa fever in West Africa.

    abstract:BACKGROUND:Infectious disease prevention and control strategies require a coordinated, transnational approach. To establish core capacities of the International Health Regulations (IHR), the World Health Organization (WHO) developed the Integrated Diseases Surveillance and Response (IDSR) strategy. Epidemic-prone Lassa...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4240-8

    authors: Keïta M,Kizerbo GA,Subissi L,Traoré FA,Doré A,Camara MF,Barry A,Pallawo R,Baldé MO,Magassouba N,Djingarey MH,Fall IS

    更新日期:2019-07-10 00:00:00

  • Examining the online approaches used by hospitals in Sydney, Australia to inform patients about healthcare associated infections and infection prevention strategies.

    abstract:BACKGROUND:Provision of information plays a critical role in supporting patients to be engaged or empowered to be involved with infection prevention measures in hospitals. This explorative study evaluated the suitability, readability and accessibility of information on healthcare associated infections (HCAIs) and infec...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2899-2

    authors: Park J,Seale H

    更新日期:2017-12-21 00:00:00

  • Deep sequencing of hepatitis C virus hypervariable region 1 reveals no correlation between genetic heterogeneity and antiviral treatment outcome.

    abstract:BACKGROUND:Hypervariable region 1 (HVR1) contained within envelope protein 2 (E2) gene is the most variable part of HCV genome and its translation product is a major target for the host immune response. Variability within HVR1 may facilitate evasion of the immune response and could affect treatment outcome. The aim of ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-14-389

    authors: Cortés KC,Zagordi O,Perlejewski K,Laskus T,Maroszek K,Bukowska-Ośko I,Pawełczyk A,Płoski R,Berak H,Horban A,Radkowski M

    更新日期:2014-07-13 00:00:00

  • Resistance of Mycobacterium tuberculosis to antibiotics in Lao PDR: first multicentric study conducted in 3 hospitals.

    abstract:BACKGROUND:It is estimated that Lao People's Democratic Republic (Lao PDR) ranks fifth among the seven countries most affected by TB in the WHO Western Pacific Region. However, because of late implementation of mycobacterial culture, no study on resistance to anti-TB drugs had been performed yet. The objective of this ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2334-13-275

    authors: Iem V,Somphavong S,Buisson Y,Steenkeste N,Breysse F,Chomarat M,Sylavanh P,Nanthavong P,Rajoharison A,Berland JL,Paboriboune P

    更新日期:2013-06-19 00:00:00

  • The global effect of maternal education on complete childhood vaccination: a systematic review and meta-analysis.

    abstract:BACKGROUND:There is an established correlation between maternal education and reduction in childhood mortality. One proposed link is that an increase in maternal education will lead to an increase in health care access and vaccine uptake. Vaccinations are a central preventative child health tool, therefore demonstratin...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/s12879-017-2890-y

    authors: Forshaw J,Gerver SM,Gill M,Cooper E,Manikam L,Ward H

    更新日期:2017-12-28 00:00:00

  • Etiology and prognosis of acute viral encephalitis and meningitis in Chinese children: a multicentre prospective study.

    abstract:BACKGROUND:In China, there were few studies about the pathogens of acute viral encephalitis and meningitis in children in recent years. The aims of this study were to characterize the etiology and prognosis of acute viral encephalitis and meningitis in Chinese children. METHODS:This was a multicentre prospective study...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12879-017-2572-9

    authors: Ai J,Xie Z,Liu G,Chen Z,Yang Y,Li Y,Chen J,Zheng G,Shen K

    更新日期:2017-07-14 00:00:00

  • Comparison of viral and epidemiological profiles of hospitalized children with severe acute respiratory infection in Beijing and Shanghai, China.

    abstract:BACKGROUND:No comparison data have been reported on viral and epidemiological profiles of hospitalized children with severe acute respiratory infection (SARI) in Beijing or Shanghai, China. METHODS:We collected 700 nasopharyngeal aspirates (NPA) from hospitalized children with SARI in Beijing (northern China) and Shan...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4385-5

    authors: Zhao Y,Lu R,Shen J,Xie Z,Liu G,Tan W

    更新日期:2019-08-20 00:00:00

  • A retrospective serological survey of hepatitis B virus infection in Northeast China.

    abstract:BACKGROUND:Hepatitis B virus (HBV) infection is a major public health burden in China although it has steadily declined over the last two decades. A valid updated prevalence of HBV infection in China relies on a large sample size. Hence this study aimed to estimate HBV seroprevalence using a large inpatient population ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4091-3

    authors: Meng J,Xu H,Sui D,Jiang J,Li J,Gao Y,Niu J

    更新日期:2019-05-20 00:00:00

  • Differential expression and predictive value of monocyte scavenger receptor CD163 in populations with different tuberculosis infection statuses.

    abstract:BACKGROUND:Monocytes are the predominant innate immune cells at the early stage of Mycobacterium tuberculosis (M. tb) infection as the host defense against intracellular pathogens. Understanding the profile of different monocyte subpopulations and the dynamics of monocyte-related biomarkers may be useful for the diagno...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-4525-y

    authors: Liu Q,Ou Q,Chen H,Gao Y,Liu Y,Xu Y,Ruan Q,Zhang W,Shao L

    更新日期:2019-11-28 00:00:00

  • The impact of virus infections on pneumonia mortality is complex in adults: a prospective multicentre observational study.

    abstract:BACKGROUND:Various viruses are known to be associated with pneumonia. However, the impact of viral infections on adult pneumonia mortality remains unclear. This study aimed to clarify the effect of virus infection on pneumonia mortality among adults stratified by virus type and patient comorbidities. METHODS:This mult...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12879-017-2858-y

    authors: Katsurada N,Suzuki M,Aoshima M,Yaegashi M,Ishifuji T,Asoh N,Hamashige N,Abe M,Ariyoshi K,Morimoto K,Adult Pneumonia Study Group-Japan.

    更新日期:2017-12-06 00:00:00

  • Lymphocyte transformation assay for C neoformans antigen is not reliable for detecting cellular impairment in patients with neurocryptococcosis.

    abstract:BACKGROUND:Cryptococcus neoformans causes meningitis and disseminated infection in healthy individuals, but more commonly in hosts with defective immune responses. Cell-mediated immunity is an important component of the immune response to a great variety of infections, including yeast infections. We aimed to evaluate a...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-12-278

    authors: Rocha KC,Pinhal C,Cavalcanti S,Vidal MS,Toscano M,Moraes-Vasconcelos D,Duarte AJ,Fonseca FL,de Abreu LC,Valenti VE,Grumach AS

    更新日期:2012-10-30 00:00:00

  • Dengue type 4 in Rio de Janeiro, Brazil: case characterization following its introduction in an endemic region.

    abstract:BACKGROUND:Due to the populations' susceptibility, DENV-4 introduction in 2010 led to the occurrence of explosive epidemics in the following years in Brazil. In 2011, DENV-4 was identified in Rio de Janeiro (RJ) and it was prevalent in 2012 and 2013. Here, we aimed to characterize clinical, epidemiological and laborato...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2488-4

    authors: Heringer M,Souza TMA,Lima MDRQ,Nunes PCG,Faria NRDC,de Bruycker-Nogueira F,Chouin-Carneiro T,Nogueira RMR,Dos Santos FB

    更新日期:2017-06-09 00:00:00

  • The risk factors of intracranial infection in patients with intracerebral hemorrhage undergone hematoma puncture: what should we care.

    abstract:BACKGROUND:Intracranial infection after puncture of cerebral hematoma in patients with intracerebral hemorrhage is very common in the department of neurosurgery, yet the relevant risks remain unknown. We attempted to analyze the risk factors of intracranial infection after puncture of cerebral hematoma, to provide insi...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05630-2

    authors: Han H,Li Y,Liu L,Liu N,Wang Y,Zhang M

    更新日期:2020-12-11 00:00:00

  • Clonal dissemination of linezolid-resistant Staphylococcus capitis with G2603T mutation in domain V of the 23S rRNA and the cfr gene at a tertiary care hospital in China.

    abstract:BACKGROUND:The present study aims to investigate the potential mechanism of linezolid-resistant Staphylococcus capitis (LRSC) isolates collected from our hospital. METHODS:The susceptibilities of 5 Staphylococcus capitis isolates displaying resistance towards linezolid were determined by E-test. Polymerase chain react...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-015-0841-z

    authors: Zhou W,Niu D,Cao X,Ning M,Zhang Z,Shen H,Zhang K

    更新日期:2015-02-26 00:00:00

  • Temporal trends in hepatitis B and C infection in family blood donors from interior Sindh, Pakistan.

    abstract:BACKGROUND:Hepatitis B (HBV) and C (HCV) infections are a serious global and national public health problem. Earlier studies have reported increasing rates of hepatitis infection in Pakistan, particularly in rural areas. Pakistan has no active surveillance program to monitor trends of these infections. The objective of...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-8-43

    authors: Mujeeb SA,Pearce MS

    更新日期:2008-04-10 00:00:00

  • Healthcare-associated infections: bacteriological characterization of the hospital surfaces in the University Hospital of Abomey-Calavi/so-ava in South Benin (West Africa).

    abstract:BACKGROUND:Healthcare-associated infections have become a public health problem, creating a new burden on medical care in hospitals. The emergence of multidrug-resistant bacteria poses a difficult task for physicians, who have limited therapeutic options. The dissemination of pathogens depends on "reservoirs", the diff...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3648-x

    authors: Afle FCD,Agbankpe AJ,Johnson RC,Houngbégnon O,Houssou SC,Bankole HS

    更新日期:2019-01-07 00:00:00

  • Pressure ulcer-related pelvic osteomyelitis: evaluation of a two-stage surgical strategy (debridement, negative pressure therapy and flap coverage) with prolonged antimicrobial therapy.

    abstract:BACKGROUND:A two-stage surgical strategy (debridement-negative pressure therapy (NPT) and flap coverage) with prolonged antimicrobial therapy is usually proposed in pressure ulcer-related pelvic osteomyelitis but has not been widely evaluated. METHODS:Adult patients with pressure ulcer-related pelvic osteomyelitis tre...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3076-y

    authors: Andrianasolo J,Ferry T,Boucher F,Chateau J,Shipkov H,Daoud F,Braun E,Triffault-Fillit C,Perpoint T,Laurent F,Mojallal AA,Chidiac C,Valour F,Lyon BJI study group.

    更新日期:2018-04-10 00:00:00

  • First infection by all four non-severe acute respiratory syndrome human coronaviruses takes place during childhood.

    abstract:BACKGROUND:Non-severe acute respiratory syndrome (non-SARS)-related human coronaviruses (HCoVs), including HCoV-229E, -HKU1, -NL63, and -OC43, have been detected in respiratory tract samples from children and adults. However, the natural prevalence of antibodies against these viruses in serum among population is unknow...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-433

    authors: Zhou W,Wang W,Wang H,Lu R,Tan W

    更新日期:2013-09-16 00:00:00

  • Potential impact of infant feeding recommendations on mortality and HIV-infection in children born to HIV-infected mothers in Africa: a simulation.

    abstract:BACKGROUND:Although breast-feeding accounts for 15-20% of mother-to-child transmission (MTCT) of HIV, it is not prohibited in some developing countries because of the higher mortality associated with not breast-feeding. We assessed the potential impact, on HIV infection and infant mortality, of a recommendation for sho...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-8-66

    authors: Atashili J,Kalilani L,Seksaria V,Sickbert-Bennett EE

    更新日期:2008-05-16 00:00:00